Tomio Arai


Affiliation: Tokyo Metropolitan Institute of Gerontology
Country: Japan


  1. Arai T, Matsuda Y, Aida J, Takubo K, Ishiwata T. Solid-type poorly differentiated adenocarcinoma of the stomach: clinicopathological and molecular characteristics and histogenesis. Gastric Cancer. 2018;: pubmed publisher
    ..In addition, from the viewpoint of histogenesis, MSI-positive solid-type PDA may originate from differentiated-type adenocarcinoma. ..
  2. Aida J, Ishizaki T, Arai T, Takubo K. Prognostication of superficial Barrett's carcinoma: a Japanese multicenter study. Hum Pathol. 2018;76:156-166 pubmed publisher
    ..Detailed histopathologic evaluation of thin-slice preparations of ER specimens is considered highly important for prognostication. ..
  3. Zhao C, Ikeda S, Arai T, Naka Mieno M, Sato N, Muramatsu M, et al. Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population. BMC Cardiovasc Disord. 2014;14:6 pubmed publisher
    ..75 [0.58-0.98], p = 0.034). rs877087 and rs2229116 of RYR3 gene are associated with atherosclerosis severity in Japanese. The functional difference caused by rs2229116 needs to be investigated. ..
  4. Arai T, Sawabe M, Hosoi T, Tanaka N. Role of DNA repair systems in malignant tumor development in the elderly. Geriatr Gerontol Int. 2008;8:65-72 pubmed publisher
  5. Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, et al. Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Mol Brain. 2015;8:50 pubmed publisher
  6. Nonaka K, Matsuda Y, Okaniwa A, Kasajima A, Sasano H, Arai T. Pancreatic gangliocytic paraganglioma harboring lymph node metastasis: a case report and literature review. Diagn Pathol. 2017;12:57 pubmed publisher
    ..Pancreatic GP is associated with a higher incidence of metastasis and larger tumor size than duodenal GPs, suggesting that the primary organ of GP is an important prognostic factor. ..
  7. Arai T, Kasahara I, Sawabe M, Honma N, Aida J, Tabubo K. Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly. Geriatr Gerontol Int. 2010;10 Suppl 1:S207-12 pubmed publisher