Research Topics
| Norihiro IkomaSummaryAffiliation: Tokai University Country: Japan Publications
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Detail Information
Publications
Random skin biopsy of intravascular large B-cell lymphoma: a case reportNorihiro Ikoma
Department of Dermatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259 1193, Japan
Tokai J Exp Clin Med 37:75-6. 2012..Immunohistochemical analysis showed that these cells were positive for CD20, CD79a, bcl-2, bcl-6 and MUM-1. From these findings, a diagnosis of intravascular large B cell lymphoma was made...- A case of atypical benign fibrous histiocytomaNorihiro Ikoma
Department of Dermatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
Tokai J Exp Clin Med 29:49-51. 2004..Clear distinction has not been made between ABFH, a variant of benign fibrous histiocytoma, and atypical fibroxanthoma, which is a variant of malignant fibrous histiocytoma. Here we report a case of ABFH with a diagnosis of the neoplasm... - Lentigo maligna occurring in a patient with the past history of laser therapyNorihiro Ikoma
Department of Dermatology, Tokai University School of Medicine, Shimokasuya 143, Isehara, Kanagawa, Japan
Tokai J Exp Clin Med 33:75-7. 2008.... - S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in the NOD/SCID/gammaCnull (NOG) mouse modelNorihiro Ikoma
Department of Dermatology, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan
Oncol Rep 14:633-7. 2005..E-cadherin gene expression was conversely inhibited in these cell lines. The increased expression of S100A4 combined with inhibited E-cadherin expression resulted in high metastatic potentials of the human melanoma cell lines in vivo... - Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/gammaCnull (NOG) miceTsuyoshi Chijiwa
Department of Pathology, Tokai University School of Medicine, Shimokasuya, Isehara, Kanagawa 259 1193, Japan
Int J Oncol 34:5-13. 2009..96+/-0.61% in A375/V, p<0.01, Welch test). These results suggest that TSP2 suppresses hematogenous metastasis through microenvironment-modification including PAI up-regulation and anti-vascularization in human malignant melanoma... - Multiple Bowen's disease in a patient with a history of possible arsenic exposure: a case reportHanako Yamaoka
Department of Dermatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259 1193, Japan
Tokai J Exp Clin Med 36:53-7. 2011..During the inquiry, we learned that since birth, he has resided in Hiratsuka City and had often used water from wells. We researched the possibilities of water and soil contaminations in the Hiratsuka area... - Protein oxidative damage and heme oxygenase in sunlight-exposed human skin: roles of MAPK responses to oxidative stressEmiko Akasaka
Department of Dermatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
Tokai J Exp Clin Med 35:152-64. 2010..Taken together, our results suggest (1) antioxidative effects of heme oxygenase-2 in chronically sunlight-exposed human skin, and that (2) activation of p38 MAPK may be responsible for oxidative stress... - Psoriasis affects patient's quality of life more seriously in female than in male in JapanTomotaka Mabuchi
Department of Dermatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259 1193, Japan
Tokai J Exp Clin Med 37:84-8. 2012..The aim of this study was to assess the quality of life (QOL) of patients with psoriasis in Japan using Dermatology Life Quality Index (DLQI). Furthermore, we had evaluated the correlation between DLQI and clinical severity of psoriasis... - A case of chromomycosis treated by surgical therapy combined with preceded oral administration of terbinafine to reduce the size of the lesionKana Tamura
Department of Dermatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
Tokai J Exp Clin Med 37:6-10. 2012..The patient was initially treated with oral terbinafine (250 mg/day) as the lesion was very large. After the 18 months treatment, the size of the lesion reduced to 1 cm, then the remaining lesion was excised... - The incidence of internal malignancies in autoimmune bullous diseasesKenichi Iwashita
Tokai University School of Medicine, Isehara, Kanagawa, Japan
Tokai J Exp Clin Med 32:42-7. 2007..Therefore it is clinically important to carry out a detailed screening for internal malignancies in patients with pemphigus as well as in patients with BP... 
A novel case of nocardiosis with skin lesion due to Nocardia araoensisEmiko Akasaka
Department of Dermatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
J Dermatol 38:702-6. 2011..Minocycline and co-trimoxazole were co-administrated, and her condition improved. To our knowledge, this is the first case in which N. araoensis was detected by analysis on rRNA base sequence in skin lesions...- A case of epidermal cyst with pilomatrical differentiationNorihiro Ikoma
Department of Dermatology, Tokai University School of Medicine, Kanagawa, Japan
Tokai J Exp Clin Med 29:127-30. 2004..We diagnosed this case as epidermal cyst with pilomatrical differentiation... - The modifier subunit of glutamate cysteine ligase relates to cisplatin resistance in human small cell lung cancer xenografts in vivoMasatake Nishi
Department of Pathology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259-1193, Japan
Oncol Rep 14:421-4. 2005..0289, correlations = 0.975), while the GCLC gene expression level was not associated with T/C%. These results suggest that the overexpression of GCLM is correlated with CDDP-resistance in SCLC xenografts in vivo...