K Ando

Summary

Affiliation: Tokai University
Country: Japan

Publications

  1. ncbi request reprint Expression of CD90 on keratinocyte stem/progenitor cells
    Y Nakamura
    Division of Hematopoiesis, Research Center for Regenerative Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259 1193, Japan
    Br J Dermatol 154:1062-70. 2006
  2. ncbi request reprint Extensive generation of human cord blood CD34(+) stem cells from Lin(-)CD34(-) cells in a long-term in vitro system
    K Ando
    Department of Hematology, Tokai University School of Medicine, Kanagawa, Japan
    Exp Hematol 28:690-9. 2000
  3. ncbi request reprint The efficient generation of CD83 positive immunocompetent dendritic cells from CD14 positive acute myelomonocytic or monocytic leukemia cells in vitro
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Leuk Res 25:249-58. 2001
  4. ncbi request reprint Extensive and long-term ex vivo production of dendritic cells from CD34 positive umbilical cord blood or bone marrow cells by novel culture system using mouse stroma
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Bohseidai, Kanagawa, 259 1193, Isehara, Japan
    J Immunol Methods 253:45-55. 2001
  5. ncbi request reprint Successful in vitro generation of Epstein-Barr virus-specific cytotoxic T lymphocytes from severe chronic active EBV patients
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Med Microbiol Immunol 189:137-45. 2001
  6. ncbi request reprint Efficient lentiviral transduction of human cord blood CD34(+) cells followed by their expansion and differentiation into dendritic cells
    M Oki
    Division of Hematology and Rheumatology, Department of Medicine, Research Center for Genetic Engineering and Cell Transplantation, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Exp Hematol 29:1210-7. 2001
  7. ncbi request reprint Humanizing bone marrow in immune-deficient mice
    K Ando
    Division of Hematopoiesis, Department of Hematology, Research Center of Regenerative Medicine, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Curr Top Microbiol Immunol 324:77-86. 2008
  8. doi request reprint C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene
    H Matsushita
    Department of Laboratory Medicine, Tokai University School of Medicine, Kanagawa, Japan
    Oncogene 27:6749-60. 2008
  9. ncbi request reprint Overexpression of a minor component of myelin basic protein isoform (17.2 kDa) can restore myelinogenesis in transgenic shiverer mice
    M Kimura
    Division of Molecular Life Science, School of Medicine, Tokai University, Bohseidai, Isehara, Kanagawa 259 11, Japan
    Brain Res 785:245-52. 1998
  10. ncbi request reprint Acute lethal injury of lung and liver in mice transplanted with ex vivo-expanded CTLs
    T Sato
    Research Center for Genetic Engineering and Cell Transplantation, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Cell Transplant 10:409-12. 2001

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Expression of CD90 on keratinocyte stem/progenitor cells
    Y Nakamura
    Division of Hematopoiesis, Research Center for Regenerative Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259 1193, Japan
    Br J Dermatol 154:1062-70. 2006
    ..Here, we report the detection of CD90(+) cells in cultured normal human epidermal keratinocytes and adult skin...
  2. ncbi request reprint Extensive generation of human cord blood CD34(+) stem cells from Lin(-)CD34(-) cells in a long-term in vitro system
    K Ando
    Department of Hematology, Tokai University School of Medicine, Kanagawa, Japan
    Exp Hematol 28:690-9. 2000
    ..This system provides a novel and potentially useful procedure to generate CD34(+) cells for clinical transplantation and gene therapy...
  3. ncbi request reprint The efficient generation of CD83 positive immunocompetent dendritic cells from CD14 positive acute myelomonocytic or monocytic leukemia cells in vitro
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Leuk Res 25:249-58. 2001
    ..They also stimulated not only allo- but auto-T lymphocytes, which thereafter became cytotoxic T lymphocytes (CTLs)...
  4. ncbi request reprint Extensive and long-term ex vivo production of dendritic cells from CD34 positive umbilical cord blood or bone marrow cells by novel culture system using mouse stroma
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Bohseidai, Kanagawa, 259 1193, Isehara, Japan
    J Immunol Methods 253:45-55. 2001
    ..In conclusion, a novel culture system using HESS-5 is useful to support a rapid and sustained generation of primitive myeloid cells which can develop into functional DCs...
  5. ncbi request reprint Successful in vitro generation of Epstein-Barr virus-specific cytotoxic T lymphocytes from severe chronic active EBV patients
    M Hagihara
    Department of Hematology and Rheumatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Med Microbiol Immunol 189:137-45. 2001
    ..These CTL lines were predominantly composed of CD4+ cells, and autologous EBCL killing was largely inhibited by an antibody against HLA-DR. These findings support the possibility of adoptive immune therapy to treat SCAEBV patients...
  6. ncbi request reprint Efficient lentiviral transduction of human cord blood CD34(+) cells followed by their expansion and differentiation into dendritic cells
    M Oki
    Division of Hematology and Rheumatology, Department of Medicine, Research Center for Genetic Engineering and Cell Transplantation, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Exp Hematol 29:1210-7. 2001
    ..CONCLUSION: Gene-modified DCs derived from ex vivo expanded CB CD34(+) cells transduced by lentiviral vector will be useful in future immunotherapy protocols...
  7. ncbi request reprint Humanizing bone marrow in immune-deficient mice
    K Ando
    Division of Hematopoiesis, Department of Hematology, Research Center of Regenerative Medicine, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Curr Top Microbiol Immunol 324:77-86. 2008
    ..These humanized mouse models are essential for testing whether the insights on hematopoiesis from mouse studies are applicable to humans before clinical application...
  8. doi request reprint C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene
    H Matsushita
    Department of Laboratory Medicine, Tokai University School of Medicine, Kanagawa, Japan
    Oncogene 27:6749-60. 2008
    ....
  9. ncbi request reprint Overexpression of a minor component of myelin basic protein isoform (17.2 kDa) can restore myelinogenesis in transgenic shiverer mice
    M Kimura
    Division of Molecular Life Science, School of Medicine, Tokai University, Bohseidai, Isehara, Kanagawa 259 11, Japan
    Brain Res 785:245-52. 1998
    ..2-kDa MBP isoform is present, has the ability to elicit CNS myelination in transgenic shi mice. This transgenic strategy will be useful for elucidating the role of each type of MBP isoform in CNS myelinogenesis...
  10. ncbi request reprint Acute lethal injury of lung and liver in mice transplanted with ex vivo-expanded CTLs
    T Sato
    Research Center for Genetic Engineering and Cell Transplantation, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    Cell Transplant 10:409-12. 2001
    ..Therefore, this protocol was shown to be effective to produce alloantigen-specific CTLs and applicable to in vitro manipulation such as retrovirus-mediated gene transfer...
  11. ncbi request reprint Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients
    M Onizuka
    Department of Hematology and Oncology, Tokai University School of Medicine, Kanagawa, Japan
    Bone Marrow Transplant 46:1113-7. 2011
    ..0010 and P=0.0021, respectively). In this study, we show that genetic variation has a predictable effect on the pharmacological responses to calcineurin inhibitors in HSCT patients...
  12. ncbi request reprint Serum stem cell growth factor for monitoring hematopoietic recovery following stem cell transplantation
    C Ito
    1Department of Hematology, Oncology and Rheumatology, Tokai University School of Medicine, Kanagawa, Japan
    Bone Marrow Transplant 32:391-8. 2003
    ..The cell population expressing SCGF in BM possess the colony-forming cell activity. Therefore, serum SCGF can be an indicator of hematopoietic recovery following SCT...
  13. ncbi request reprint Reconstitution of immune systems in RAG2-/- mice by transfer with interleukin-12-induced splenic hematopoietic progenitor cells
    T Yahata
    Department of Immunology, Tokai University School of Medicine, Bohseidai, Isehara, Japan
    Immunol Lett 62:165-70. 1998
    ..Thus, the evidence that IL-12 has a capability of inducing hematopoietic progenitor cells possessing stem cell-like activity in vivo, indicated another important immunomodulating activity of IL-12 in immunotherapy...
  14. pmc Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation
    K Schindowski
    INSERM, U837, Place de Verdun, Lille Cedex, France
    Genes Brain Behav 7:92-100. 2008
    ..Altogether, these data suggest that cell cycle events in THY-Tau22 are resulting from neurogenesis in young animals and cell death in older ones. It suggests that neuronal cell death in such models is much more complex than believed...
  15. ncbi request reprint Gracile axonal dystrophy (GAD), a new neurological mutant in the mouse
    K Yamazaki
    Laboratory of Animal Genetics, Faculty of Agriculture, Nagoya University, Japan
    Proc Soc Exp Biol Med 187:209-15. 1988
    ..The mutation is inherited as an autosomal recessive trait. It was, therefore, named gracile axonal dystrophy (GAD) with the gene symbol gad. The mice could be a new pathological model for the study of neuroaxonal dystrophy...
  16. ncbi request reprint Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5
    K Iijima
    Laboratory of Neurobiophysics, School of Pharmaceutical Sciences, The University of Tokyo, Japan
    J Neurochem 75:1085-91. 2000
    ..The expression of APP was unaffected in antisense-treated neurons. These results indicate that in neurons APP is phosphorylated by Cdk5, and that this may play a role in its localization...
  17. ncbi request reprint [Elevated immunoreactive-somatostatin levels in the brain of ataxic mutant mice]
    K Matsui
    National Institute of Neuroscience, N C N P, Tokyo, Japan
    Jikken Dobutsu 37:263-8. 1988
    ..The present results suggest that elevated levels of IR-SRIF in the brain may play a role in the mechanism underlying the manifestation of ataxia in ataxic mutant mice, especially in Rolling Mouse Nagoya and PCD...
  18. ncbi request reprint [Fundamental study on ataxic mice (wriggle mouse Sagami)]
    K Matsui
    Jikken Dobutsu 36:185-9. 1987
    ..These results indicate that the mechanism inducing ataxia and abnormal gait pattern in WMS may be different from those in other genetically-determined ataxic mice, e. g., Rolling mouse Nagaya (RMN), PCD, Staggerer and Reeler...
  19. ncbi request reprint Maturation-dependent change and regional variations in acoustic stiffness of rabbit articular cartilage: an examination of the superficial collagen-rich zone of cartilage
    H Kuroki
    Department of Physical Therapy, School of Health Sciences, Faculty of Medicine, Kyoto University, 53 Kawahara cho, Shogoin, Sakyo ku, Kyoto, Japan
    Osteoarthritis Cartilage 14:784-92. 2006
    ..The purpose of the study was to investigate maturation-dependent changes of acoustic (ultrasound) stiffness and other ultrasound features of articular cartilage in healthy rabbit knees...
  20. ncbi request reprint Transplantation of human neural stem cells for spinal cord injury in primates
    A Iwanami
    Department of Physiology, Keio University School of Medicine, Shinjuku, Tokyo, Japan
    J Neurosci Res 80:182-90. 2005
    ..These findings show that NSPC transplantation was effective for SCI in primates and suggest that human NSPC transplantation could be a feasible treatment for human SCI...
  21. ncbi request reprint Complex chromosomal rearrangements induced in vivo by heavy ions
    M Durante
    Department of Physics, University Federico II, Naples, Italy
    Cytogenet Genome Res 104:240-4. 2004
    ..Complex chromosomal rearrangements do not represent a practical biomarker of radiation quality in our test subjects...
  22. ncbi request reprint Isolation and characterization of an alternatively spliced variant of transcription factor Islet-1
    K Ando
    Frontier Collaborative Research Center, Tokyo Institute of Technology, Yokohama 226 8503, Japan
    J Mol Endocrinol 31:419-25. 2003
    ..Therefore, the transcriptional activity of Isl1 is potentially regulated by the alternative splicing of its mRNA and by phosphorylation...
  23. ncbi request reprint Washout measurement of radioisotope implanted by radioactive beams in the rabbit
    H Mizuno
    Department of Quantum Science and Energy Engineering, Tohoku University Graduate School of Engineering, Aoba yama 4, Sendai 980 8579, Japan
    Phys Med Biol 48:2269-81. 2003
    ..0 s), 30% (140 s) and 35% (10 191 s) for brain and 30% (10 s), 19% (195 s) and 52% (3175 s) for thigh muscle. The washout effect must be taken into account for the verification of treatment plans by means of positron camera measurements...
  24. ncbi request reprint Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells
    C Shao
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Inage, Chiba, Japan
    Int J Radiat Biol 78:837-44. 2002
    ..To investigate the signal factor and its function in the medium-mediated bystander effect during heavy-ion irradiation of human salivary gland (HSG) neoplastic cells...
  25. ncbi request reprint Absence of a CD34- hematopoietic precursor population in recipients of CD34+ stem cell transplantation
    S Kato
    Research Center for Cell Transplantation, Tokai University, School of Medicine, Kanagawa, Japan
    Bone Marrow Transplant 28:587-95. 2001
    ..We conclude that recipients of CD34-enriched transplantation appear to have defects in their CD34(-) precursor population. The clinical significance of these defects will be determined in a life-long follow-up of these patients...
  26. ncbi request reprint Neurotransmitter abnormality in Rolling mouse Nagoya, an ataxic mutant mouse
    O Muramoto
    Brain Res 215:295-304. 1981
    ....
  27. ncbi request reprint Anaplastic large-cell lymphoma which showed severe inflammatory status and myelodysplasia with increased VEGF and IL-6 serum levels after long-term immunosuppressive therapy
    T Shimamoto
    First Department of Internal Medicine, Tokyo Medical University, Japan
    Am J Hematol 66:49-52. 2001
    ..We assumed that ALCL resulted from long-term immunosuppressive therapy and that the up-regulation of IL-6 and VEGF played a role in pathogenesis of this type of lymphoma...
  28. ncbi request reprint Pro-thyrotropin-releasing hormone concentrations in the brain of ataxic mice
    T Mitsuma
    Fourth Department of Internal Medicine, Aichi Medical University, Japan
    J Neurol Sci 98:163-7. 1990
    ..These findings suggest that changes in pro-TRH concentrations in the brain may play a pathophysiological role in ataxic mice...