Hitoshi Oshitani

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. pmc Evolutionary analyses on the HA gene ofpandemic H1N1/09: early findings
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi Aoba ku, Sendai, Japan
    Bioinformation 5:7-10. 2010
  2. pmc Measles outbreaks in displaced populations: a review of transmission, morbidity and mortality associated factors
    Isidore K Kouadio
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    BMC Int Health Hum Rights 10:5. 2010
  3. ncbi request reprint [Influenza pandemic (H1N1) 2009]
    Hitoshi Oshitani
    Department of Virology Tohoku University Graduate School of Medicine
    Uirusu 59:139-44. 2009
  4. pmc Major issues and challenges of influenza pandemic preparedness in developing countries
    Hitoshi Oshitani
    Tohoku University Graduate School of Medicine, Sendai, Japan
    Emerg Infect Dis 14:875-80. 2008
  5. ncbi request reprint Potential benefits and limitations of various strategies to mitigate the impact of an influenza pandemic
    Hitoshi Oshitani
    Tohoku University Graduate School of Medicine, Department of Virology, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Infect Chemother 12:167-71. 2006
  6. doi request reprint Genetic characterization of human respiratory syncytial virus detected in hospitalized children in the Philippines from 2008 to 2012
    Ayumu Ohno
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi, Aoba, Sendai, Miyagi 980 8575, Japan
    J Clin Virol 57:59-65. 2013
  7. doi request reprint Reassortment between amantadine-resistant and -sensitive H1N1 influenza A viruses generated an amantadine-sensitive virus during the 2007-2008 season
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Infect Dis 200:1766-73. 2009
  8. pmc Antigenic and receptor binding properties of enterovirus 68
    Tadatsugu Imamura
    Tohoku University Graduate School of Medicine, Sendai, Japan
    J Virol 88:2374-84. 2014
  9. pmc Detection of human rhinovirus C viral genome in blood among children with severe respiratory infections in the Philippines
    Naoko Fuji
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    PLoS ONE 6:e27247. 2011
  10. pmc Molecular evolution of enterovirus 68 detected in the Philippines
    Tadatsugu Imamura
    Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 8:e74221. 2013

Collaborators

  • Akira Suzuki
  • Taro Kamigaki
  • Yuki Furuse
  • Mariko Saito
  • Beatriz P Quiambao
  • Satoshi Inoue
  • Takashi Okada
  • Xiang Huo
  • Mary E Miranda
  • Yasuo Suzuki
  • Katsumi Mizuta
  • Dai Yamamoto
  • Tatsuo Omura
  • Yoshifumi Masago
  • Yoko Matsuzaki
  • Hiroshi Suzuki
  • B Olowokure
  • Gina Samaan
  • Isidore K Kouadio
  • Hirokazu Kimura
  • Tadatsugu Imamura
  • Naoko Fuji
  • Socorro Lupisan
  • Raita Tamaki
  • Remigio Olveda
  • Nao Nukiwa
  • Kentaro Tohma
  • Michiko Okamoto
  • Hazel Galang
  • Chandra Nath Roy
  • Lydia Sombrero
  • Rapunzel Aniceto
  • Alexanderyn Burmaa
  • Pagbajabyn Nymadawa
  • Reiko Saito
  • Ayumu Ohno
  • Mihyun Kim
  • Lea Necitas Apostol
  • Nao Nukiwa-Souma
  • Lea Necitas G Apostol
  • Tatsuya Ikeda
  • Sosorbaramyn Tsatsral
  • Ishiin Od
  • Badarchiin Darmaa
  • Takashi Odagiri
  • Ned Stafford
  • Philippe Calain
  • Takatsugu Sakai
  • Hiroaki Hiramatsu
  • Shin ichi Nakakita
  • S Perlman
  • Catalino S Demetria
  • Daria L Manalo
  • Kan Etsu Sugawara
  • Jun Ryan C Orbina
  • Laarni T Tuason
  • Akira Noguchi
  • Jaime M Opinion
  • Satoshi Mimura
  • Hirono Otomaru
  • Arlene V Santo
  • Amado Tandoc
  • Edgardo E Daya
  • Rutchie J Egos
  • Noel G Macalalad
  • Chieko Abiko
  • Tsutomu Itagaki
  • Fem Julia Paladin
  • Yuriko Katsushima
  • Kanako Otani
  • Fumio Katsushima
  • Hiroshi Nakagawa
  • Namuuntsetsegiin Bayasgalan
  • Yoko Aoki
  • Namuutsetsegiin Bayasgalan
  • Tomifumi Imagawa
  • Badarchiin Darma
  • Analisa Bautista
  • Kazuhisa Kawamura
  • Masahiro Noda
  • Tadayuki Ahiko
  • Rex Centeno
  • Soccoro Lupisan
  • Jigjidsurengiin Od
  • Hitoshi Oshitan
  • Rentsengiin Tuul
  • Tsedenbalyn Naranzul
  • Luvsanbaldangiin Enkhbaatar
  • Baataryn Gantsooj
  • Kozue Shimabukuro

Detail Information

Publications54

  1. pmc Evolutionary analyses on the HA gene ofpandemic H1N1/09: early findings
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi Aoba ku, Sendai, Japan
    Bioinformation 5:7-10. 2010
    ..Among them, position 206 is located in an antigenic site. We did not find significant negative selection on any of the receptor binding sites. The virus has been evolving under unique selective pressure...
  2. pmc Measles outbreaks in displaced populations: a review of transmission, morbidity and mortality associated factors
    Isidore K Kouadio
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    BMC Int Health Hum Rights 10:5. 2010
    ..In recent years, refugees and internally displaced persons have been increasing. Our study aims to define the epidemiological characteristics and risk factors associated with measles outbreaks in displaced populations...
  3. ncbi request reprint [Influenza pandemic (H1N1) 2009]
    Hitoshi Oshitani
    Department of Virology Tohoku University Graduate School of Medicine
    Uirusu 59:139-44. 2009
    ..Many aspects of pandemic (H1N1) 2009 are different from what we had been expecting. We should reconsider the concepts and the strategies for influenza pandemic by reviewing current pandemic (H1N1)...
  4. pmc Major issues and challenges of influenza pandemic preparedness in developing countries
    Hitoshi Oshitani
    Tohoku University Graduate School of Medicine, Sendai, Japan
    Emerg Infect Dis 14:875-80. 2008
    ..Such an event will inevitably have a global effect. Therefore, improving pandemic preparedness in every country, particularly developing ones, is urgently needed...
  5. ncbi request reprint Potential benefits and limitations of various strategies to mitigate the impact of an influenza pandemic
    Hitoshi Oshitani
    Tohoku University Graduate School of Medicine, Department of Virology, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Infect Chemother 12:167-71. 2006
    ..There are still significant gaps in the scientific evidence of the way in which influenza viruses are transmitted. Further studies should be conducted to define the basic transmission patterns of influenza viruses...
  6. doi request reprint Genetic characterization of human respiratory syncytial virus detected in hospitalized children in the Philippines from 2008 to 2012
    Ayumu Ohno
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi, Aoba, Sendai, Miyagi 980 8575, Japan
    J Clin Virol 57:59-65. 2013
    ..Human respiratory syncytial virus (HRSV) is the leading cause of acute lower respiratory tract infection in infants and young children. However, molecular characteristic of HRSV is still unknown in the Philippines...
  7. doi request reprint Reassortment between amantadine-resistant and -sensitive H1N1 influenza A viruses generated an amantadine-sensitive virus during the 2007-2008 season
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Infect Dis 200:1766-73. 2009
    ..The results suggest that it is necessary to monitor genome dynamics to understand the evolution and mechanism of the emergence and spread of antiviral resistance among influenza A viruses...
  8. pmc Antigenic and receptor binding properties of enterovirus 68
    Tadatsugu Imamura
    Tohoku University Graduate School of Medicine, Sendai, Japan
    J Virol 88:2374-84. 2014
    ..Additionally, we revealed that EV68 preferably binds to α2-6 SAs. This is the first report describing the properties of EV68 receptor binding to the specific types of sialic acids...
  9. pmc Detection of human rhinovirus C viral genome in blood among children with severe respiratory infections in the Philippines
    Naoko Fuji
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    PLoS ONE 6:e27247. 2011
    ..This finding suggests that the 5'NCR region may be associated with viremia...
  10. pmc Molecular evolution of enterovirus 68 detected in the Philippines
    Tadatsugu Imamura
    Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 8:e74221. 2013
    ..Detection of Enterovirus 68 (EV68) has recently been increased. However, underlying evolutionary mechanism of this increasing trend is not fully understood...
  11. pmc Respiratory viruses from hospitalized children with severe pneumonia in the Philippines
    Akira Suzuki
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    BMC Infect Dis 12:267. 2012
    ..Pneumonia remains a leading cause of child death in developing countries. The viruses in severe pneumonia remain poorly defined...
  12. pmc Occurrence of mixed populations of influenza A viruses that can be maintained through transmission in a single host and potential for reassortment
    Yuki Furuse
    Department of Virology, Tohoku University, Graduate School of Medicine, 2 1 Seiryou machi, Aoba ku, Sendai, 980 8575, Japan
    J Clin Microbiol 48:369-74. 2010
    ..However, the proportion of these, which can be less than 1%, is too low to be detected by conventional methods. Such mixed populations in which reassortment occurs may have a significant role in the evolution of viruses...
  13. pmc Detection of non-polio enteroviruses from 17 years of virological surveillance of acute flaccid paralysis in the Philippines
    Lea Necitas Apostol
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Med Virol 84:624-31. 2012
    ..Despite some limitations in this study, plural NPEVs with multiple patterns of circulation in the Philippines for 17 years were identified...
  14. doi request reprint Comparison of selection pressures on the HA gene of pandemic (2009) and seasonal human and swine influenza A H1 subtype viruses
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, 980 8575, Japan
    Virology 405:314-21. 2010
    ..The evolutionary characteristics of the H1 gene of the 2009 H1N1 virus differed from those of seasonal and swine viruses...
  15. ncbi request reprint Monitoring of influenza viruses in the aftermath of the Great East Japan earthquake
    Kentaro Tohma
    Department of Virology, Tohoku University School of Medicine, Sendai, Japan
    Jpn J Infect Dis 65:542-4. 2012
    ..The Yamagata lineage of influenza B was detected in one patient from western Japan, indicating the importing of viruses into the affected area...
  16. pmc Genetic diversity and molecular characterization of enteroviruses from sewage-polluted urban and rural rivers in the Philippines
    Lea Necitas G Apostol
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Virus Genes 45:207-17. 2012
    ....
  17. ncbi request reprint Phylogeographic analysis of rabies viruses in the Philippines
    Kentaro Tohma
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan Electronic address
    Infect Genet Evol 23:86-94. 2014
    ....
  18. pmc Large-scale sequence analysis of M gene of influenza A viruses from different species: mechanisms for emergence and spread of amantadine resistance
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine 2 1 Seiryou mach, Aoba ku, Sendai, 980 8575, Japan
    Antimicrob Agents Chemother 53:4457-63. 2009
    ..Because the recent rapid increase in drug-resistant virus is associated with the substitution at position 31, the resistance may not be related to drug use...
  19. pmc Enterovirus 68 among children with severe acute respiratory infection, the Philippines
    Tadatsugu Imamura
    Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Emerg Infect Dis 17:1430-5. 2011
    ..All 21 patients we identified had severe illness, and 2 died, possibly the first reported fatal cases associated with EV68 infection. Our study suggests that EV68 may be a possible causative agent of severe respiratory illnesses...
  20. ncbi request reprint Differentiation of human influenza A viruses including the pandemic subtype H1N1/2009 by conventional multiplex PCR
    Yuki Furuse
    Tohoku University Graduate School of Medicine, Department of Virology, 2 1 Seiryou machi Aoba ku Sendai 980 8575, Japan
    J Virol Methods 168:94-7. 2010
    ..This is a highly sensitive method and its cost is low. Influenza surveillance using this assay would provide significant information on the epidemiology of both pandemic and seasonal influenza...
  21. ncbi request reprint Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes
    Tadatsugu Imamura
    Tohoku University School of Medicine, Sendai, Japan
    Influenza Other Respir Viruses 8:21-4. 2014
    ..Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations. ..
  22. ncbi request reprint [Researches on virology at the Tohoku University Research Center in the Philippines]
    Hitoshi Oshitani
    Department of Virology, Tohoku University Graduate School of Medicine
    Uirusu 63:45-50. 2013
    ..Based on these studies, we initiated more comprehensive researches in the Philippines since 2010. ..
  23. ncbi request reprint Detection and serotyping of human adenoviruses from patients with influenza-like illness in mongolia
    Kentaro Tohma
    Department of Virology, Tohoku University School of Medicine, Sendai, Japan
    Jpn J Infect Dis 65:289-94. 2012
    ..There was no difference between the amino acid sequences of the hexon and fiber genes that may affect tissue tropism in Mongolian strains and those in EKC-causing strains...
  24. doi request reprint Simplified screening method for detecting oseltamivir resistant pandemic influenza A (H1N1) 2009 virus by a RT-PCR/restriction fragment length polymorphism assay
    Nao Nukiwa
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    J Virol Methods 170:165-8. 2010
    ..This RT-PCR/RFLP assay is a simple method and also very specific and sensitive for detecting the H275Y mutation of pandemic influenza A (H1N1) 2009 viruses, and can be used in resource-limited settings...
  25. pmc Interruption of the circulation of an indigenous measles genotype and the introduction of other genotypes after a mass vaccination campaign in the Philippines
    Naoko Fuji
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    J Med Virol 83:1424-7. 2011
    ..However, a re-emergence of measles cases occurred in 2007, which was caused by other genotypes and the previous circulating genotype had disappeared...
  26. doi request reprint Reassortment between swine influenza A viruses increased their adaptation to humans in pandemic H1N1/09
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi Aoba ku, Sendai 980 8575, Japan
    Infect Genet Evol 10:569-74. 2010
    ..We indicate the sites that probably contributed to the acquisition of efficient human-to-human transmission...
  27. doi request reprint Viruses that cross borders: factors responsible for global dissemination of viral infections
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Intervirology 54:246-52. 2011
    ..In contrast, for some other viruses, genetically similar strains can spread and circulate all over the world. This study addresses global dissemination of various viral infections...
  28. pmc Genetic diversity and geographic distribution of genetically distinct rabies viruses in the Philippines
    Mariko Saito
    Tohoku University Graduate School of Medicine, Sendai City, Miyagi, Japan
    PLoS Negl Trop Dis 7:e2144. 2013
    ..Understanding the phylogeography of rabies viruses is important for establishing a more effective and feasible control strategy...
  29. pmc Evaluating influenza disease burden during the 2008-2009 and 2009-2010 influenza seasons in Mongolia
    Nao Nukiwa
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Western Pac Surveill Response J 2:16-22. 2011
    ..Although mortality impact also should be considered, we believe that our findings can be useful in formulating an influenza control strategy during influenza epidemic periods in Mongolia. ..
  30. doi request reprint Cumulative incidence of pandemic influenza A (H1N1) 2009 by a community-based serological cohort study in Selenghe Province, Mongolia
    Alexanderyn Burmaa
    National Influenza Center, National Center of Communicable Diseases, Ulaanbaatar, Mongolia
    Influenza Other Respir Viruses 6:e97-e104. 2012
    ..None of the study participants had been vaccinated for pandemic A (H1N1) 2009 before the second samples were collected...
  31. pmc Influenza transmission in a community during a seasonal influenza A(H3N2) outbreak (2010-2011) in Mongolia: a community-based prospective cohort study
    Nao Nukiwa-Souma
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 7:e33046. 2012
    ..However, the overall picture of community transmission is not well defined during actual outbreaks. We conducted a community-based prospective cohort study to describe the transmission characteristics of influenza in Mongolia...
  32. pmc Origin of measles virus: divergence from rinderpest virus between the 11th and 12th centuries
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai City, Japan
    Virol J 7:52. 2010
    ..In such cases, investigating measles would give important information about the course of emerging infectious diseases...
  33. pmc Evolution of the M gene of the influenza A virus in different host species: large-scale sequence analysis
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Virol J 6:67. 2009
    ..Besides, novel vaccines targeting M1 or M2 protein to confer cross subtype protection have been under development. We conducted the present study to investigate the evolution of the M gene by analyzing its sequence in different species...
  34. doi request reprint Detection of novel respiratory viruses from influenza-like illness in the Philippines
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Med Virol 82:1071-4. 2010
    ..Human metapneumovirus, human bocavirus, human coronavirus HKU1, KI virus, and WU virus were detected for the first time in the Philippines; Melaka virus was not found...
  35. pmc Reversion of influenza A (H3N2) virus from amantadine resistant to amantadine sensitive by further reassortment in Japan during the 2006-to-2007 influenza season
    Yuki Furuse
    Tohoku University Graduate School of Medicine, Aoba ku, Sendai 980 8575, Japan
    J Clin Microbiol 47:841-4. 2009
    ..Whole-genome sequencing results indicated that this was due to a further reassortment event...
  36. pmc Investigation of an Influenza A (H3N2) outbreak in evacuation centres following the Great East Japan earthquake, 2011
    Taro Kamigaki
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 9808575, Japan
    BMC Public Health 14:34. 2014
    ..At the time of the Great East Japan Earthquake on 11 March 2011, influenza A (H3N2) was still circulating and there was a heightened concern regarding severe outbreaks due to influenza A (H3N2)...
  37. ncbi request reprint [Lessons learned from pandemic (H1N1) 2009: Japan and global prospective]
    Taro Kamigaki
    Department of Virology, Tohoku University Graduate School of Medicine
    Nihon Rinsho 68:1605-10. 2010
    ..It is important to identify some gaps in the implementation of interventions for further preparedness...
  38. ncbi request reprint [Epidemiological study of health impact on influenza outpatients during 2008-2009 influenza season, Shonai, Yamagata]
    Nao Nukiwa
    Department of Virology, Tohoku University Graduate School of Medicine
    Kansenshogaku Zasshi 84:52-8. 2010
    ..This in turns means that an urgent need will arise for appropriate measures reducing this potentially huge burden during pandemic (H1N1) 2009 outbreak in Japan...
  39. ncbi request reprint [Encephalitis and encephalopathy associated with pandemic flu]
    Raita Tamaki
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Brain Nerve 61:153-60. 2009
    ..In addition, we have also reviewed a few human cases of avian influenza A (H5N1) infection where the central nervous system (CNS) are involved...
  40. ncbi request reprint Analysis of medical consultation interval between the symptom onset and consultation observed in multiple medical facilities in Odate city, Japan, 2011/2012 and 2012/2013 seasons
    Xiang Huo
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan Department of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China
    J Infect Chemother 20:370-4. 2014
    ..And the predictors or determinants for longer medical consultation interval have not been well-defined...
  41. doi request reprint Evolution of the influenza A virus untranslated regions
    Yuki Furuse
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryou machi Aoba ku, Sendai 980 8575, Japan
    Infect Genet Evol 11:1150-4. 2011
    ..In the future, clarifying the detailed mechanisms of packaging as well as the function of the RNA sequence in the untranslated region will increase the understanding of viral life cycles and evolution...
  42. doi request reprint Lancet Conferences: Influenza in the Asia-Pacific
    Taro Kamigaki
    Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Expert Rev Vaccines 8:1527-9. 2009
    ..In this article, the authors have tried to summarize this conference and discuss future prospects of pandemic preparedness and response...
  43. ncbi request reprint [Infectious disease surveillance in Miyagi after the Great East Japan Earthquake]
    Mihyun Kim
    Department of Virology, Tohoku University Graduate School of Medicine
    Nihon Koshu Eisei Zasshi 60:659-64. 2013
    ..In this study, we summarized the monitoring activities of infectious diseases through this surveillance after the earthquake...
  44. doi request reprint Acute respiratory infections due to enterovirus 68 in Yamagata, Japan between 2005 and 2010
    Tatsuya Ikeda
    Department of Microbiology, Yamagata Prefectural Institute of Public Health, Yamagata, Japan
    Microbiol Immunol 56:139-43. 2012
    ..Phylogenetic analysis indicated that plural genetically distinct clusters co-circulated. These results suggest that that difficulty in EV68 isolation leads to an underestimation of the prevalence of EV68 infections...
  45. pmc Epidemiological characteristics and low case fatality rate of pandemic (H1N1) 2009 in Japan
    Taro Kamigaki
    Department of Virology, Tohoku University Graduate School of Medicine
    PLoS Curr 1:RRN1139. 2009
    ..However, CFRs are higher in small children (<5 years) and adults. The transmission to these age groups may possibly have been minimized through aggressive suspension of classes in schools...
  46. ncbi request reprint Mucosal immunity against influenza induced by attenuated recombinant Sendai virus
    Tadatsugu Imamura
    Department of Virology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575, Japan
    Expert Rev Vaccines 10:1393-5. 2011
    ..Intranasal immunization of mice with GP42-H1 induced HA-specific IgG and IgA antibodies in sera and mucosal sites without causing any disease symptoms. Immunized mice were also protected from lethal dose challenge of influenza A virus...
  47. pmc Detection of amantadine-resistant influenza A virus strains in nursing homes by PCR-restriction fragment length polymorphism analysis with nasopharyngeal swabs
    Reiko Saito
    Department of Public Health, Niigata University, School of Medicine, Niigata City, Niigata, 951 8510, Japan
    J Clin Microbiol 40:84-8. 2002
    ....
  48. ncbi request reprint The effectiveness of influenza vaccine against influenza a (H3N2) virus infections in nursing homes in Niigata, Japan, during the 1998-1999 and 1999-2000 seasons
    Reiko Saito
    Department of Public Health, Niigata University School of Medicine, Niigata City, Japan
    Infect Control Hosp Epidemiol 23:82-6. 2002
    ..To evaluate the effectiveness of influenza vaccines against influenza-like illness (ILI) among nursing home residents...
  49. pmc Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2
    Reiko Saito
    Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata City, Niigata Prefecture 951 8510, Japan
    J Clin Microbiol 41:2164-5. 2003
    ..Predominant amino acid substitutions in M2 protein occurred at position 31 (serine to asparagine) in H3N2 strains and at position 27 (valine to alanine) in H1N1 strains...
  50. ncbi request reprint Emergence of amantadine-resistant influenza A viruses: epidemiological study
    Hiroshi Suzuki
    Department of Public Health, Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata 951 8510, Japan
    J Infect Chemother 9:195-200. 2003
    ..Measures should be taken to reduce contact, as much as possible, between persons taking and those not taking antiviral drugs for treatment or chemoprophylaxis...
  51. ncbi request reprint Can oral cholera vaccination play a role in controlling a cholera outbreak?
    Philippe Calain
    WHO Western Pacific Regional Office, Manila, Philippines
    Vaccine 22:2444-51. 2004
    ..Retrospective analysis suggests that mass vaccination with oral cholera vaccines can be a useful adjunct tool for controlling outbreaks, particularly if implemented early in association with other standard control measures...
  52. ncbi request reprint Hitoshi Oshitani: watching out for an influenza pandemic
    Ned Stafford
    Lancet 366:1601. 2005
  53. pmc Rumor surveillance and avian influenza H5N1
    Gina Samaan
    Western Pacific Regional Office of the World Health Organization, Manila, Philippines
    Emerg Infect Dis 11:463-6. 2005
    ..The World Health Organization's Western Pacific Regional Office identified 40 rumors; 9 were verified to be true. Rumor surveillance informed immediate public health action and prevented unnecessary and costly responses...
  54. ncbi request reprint Implementing the new International Health Regulations in the Pacific--challenges and opportunities
    Hitoshi Oshitani
    Communicable Disease Surveillance and Response, WHO Regional Office for the Western Pacific, Manila, Philippines
    Pac Health Dialog 12:135-43. 2005
    ....