Susumu Ogawa

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. ncbi request reprint Effects of monotherapy of temocapril or candesartan with dose increments or combination therapy with both drugs on the suppression of diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, Sendai, Japan
    Hypertens Res 30:325-34. 2007
  2. doi request reprint Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure
    Susumu Ogawa
    Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Hospital, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Hypertension 56:471-6. 2010
  3. doi request reprint Combination therapy with renin-angiotensin system inhibitors and the calcium channel blocker azelnidipine decreases plasma inflammatory markers and urinary oxidative stress markers in patients with diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Aoba ku, Sendai, Japan
    Hypertens Res 31:1147-55. 2008
  4. pmc Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1 1 Seiryo cho, Aoba ku, Sendai 980 8574, Japan
    Clin J Am Soc Nephrol 3:362-8. 2008
  5. ncbi request reprint Spironolactone further reduces urinary albumin excretion and plasma B-type natriuretic peptide levels in hypertensive type II diabetes treated with angiotensin-converting enzyme inhibitor
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Hypertension, Tohoku University Hospital, Sendai, Japan
    Clin Exp Pharmacol Physiol 33:477-9. 2006
  6. ncbi request reprint Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, Sendai 980 8574, Japan
    Hypertension 47:699-705. 2006
  7. pmc Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats
    Xianguang Chen
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 36:361-7. 2013
  8. doi request reprint Blockade of angiotensin II type-1 receptor increases salt sensitivity in Sprague-Dawley rats
    Satoshi Endo
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Tohoku University, Sendai, Japan
    Hypertens Res 32:513-9. 2009
  9. pmc Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats
    Qi Guo
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 35:48-54. 2012
  10. doi request reprint Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation
    Chunyan Hu
    Division of Nephrology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Hypertens 30:1620-31. 2012

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Effects of monotherapy of temocapril or candesartan with dose increments or combination therapy with both drugs on the suppression of diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, Sendai, Japan
    Hypertens Res 30:325-34. 2007
    ..Even among patients treated with an ACEI and/or ARB, lowering BP is important...
  2. doi request reprint Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure
    Susumu Ogawa
    Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Hospital, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Hypertension 56:471-6. 2010
    ..DG is an independent risk factor for the percentage change of ACR. MG is a predictor in type 2 diabetic patients of intima-media thickening, of increase of PWV, and of elevation of SBP...
  3. doi request reprint Combination therapy with renin-angiotensin system inhibitors and the calcium channel blocker azelnidipine decreases plasma inflammatory markers and urinary oxidative stress markers in patients with diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Aoba ku, Sendai, Japan
    Hypertens Res 31:1147-55. 2008
    ....
  4. pmc Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1 1 Seiryo cho, Aoba ku, Sendai 980 8574, Japan
    Clin J Am Soc Nephrol 3:362-8. 2008
    ....
  5. ncbi request reprint Spironolactone further reduces urinary albumin excretion and plasma B-type natriuretic peptide levels in hypertensive type II diabetes treated with angiotensin-converting enzyme inhibitor
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Hypertension, Tohoku University Hospital, Sendai, Japan
    Clin Exp Pharmacol Physiol 33:477-9. 2006
    ..Blood pressure levels in both groups were comparable. 5. In conclusion, additional therapy with spironolactone in ACEI treatment exerts a renoprotective, as well as cardioprotective, effect in hypertensive diabetes...
  6. ncbi request reprint Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, Sendai 980 8574, Japan
    Hypertension 47:699-705. 2006
    ..Our results may help to explain the clinical observation that ARB reduces urinary albumin excretion very efficiently in some patients but not in others...
  7. pmc Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats
    Xianguang Chen
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 36:361-7. 2013
    ..These results suggest that MG-induced hypertension and cardio-renal injury and increased inflammation and carbonyl and oxidative stress, which were partially preventable by an ARB...
  8. doi request reprint Blockade of angiotensin II type-1 receptor increases salt sensitivity in Sprague-Dawley rats
    Satoshi Endo
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Tohoku University, Sendai, Japan
    Hypertens Res 32:513-9. 2009
    ..We conclude that OLM and HCTZ could be a useful combination for reduction of blood pressure even under high salt intake without changes in urinary oxidative stress levels...
  9. pmc Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats
    Qi Guo
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 35:48-54. 2012
    ..These results indicate that losartan reverses HCTZ-exacerbated insulin resistance, which can be mediated through the modulation of muscular circulation in rats with impaired glucose metabolism...
  10. doi request reprint Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation
    Chunyan Hu
    Division of Nephrology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Hypertens 30:1620-31. 2012
    ..Studies were designed to determine the effects of a specific TCC blocker, R(-) efonidipine [R(-)EFO], on the regulation of renal circulation...
  11. ncbi request reprint Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Tohoku J Exp Med 223:133-5. 2011
    ..The hypotensive effect is apparent with the alternate-day regimen of sitagliptin at a lower dose compared to the everyday medication...
  12. doi request reprint Identification of the stages of diabetic nephropathy at which angiotensin II receptor blockers most effectively suppress albuminuria
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai, Japan
    Am J Hypertens 26:1064-9. 2013
    ..We sought to define the relationship between ROS and ACR and establish the stage at which ARBs exert maximal AAEs...
  13. ncbi request reprint A decline in glomerular filtration rate rather than renal arterial stenotic lesions, per se, predicts cardiovascular-renal events in type 2 diabetic patients
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital
    Circ J 77:2816-22. 2013
    ..Hence, the features to determine which best predicts the onset of CVREs in such patients were compared...
  14. ncbi request reprint The glucagon-like peptide-1 analog liraglutide suppresses ghrelin and controls diabetes in a patient with Prader-Willi syndrome
    Miho Senda
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai 980 8574, Japan
    Endocr J 59:889-94. 2012
    ....
  15. doi request reprint Role of renal medullary oxidative and/or carbonyl stress in salt-sensitive hypertension and diabetes
    Takefumi Mori
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Clin Exp Pharmacol Physiol 39:125-31. 2012
    ..Oxidative and/or carbonyl stress may be the next target of drug discovery to protect against salt-sensitive hypertension and associated end-organ damage...
  16. doi request reprint Methylglyoxal contributes to the development of insulin resistance and salt sensitivity in Sprague-Dawley rats
    Qi Guo
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai 980 8574, Japan
    J Hypertens 27:1664-71. 2009
    ..The present study was designed to investigate whether methylglyoxal could directly induce insulin resistance and salt sensitivity in Sprague-Dawley rats...
  17. ncbi request reprint [Elevated plasma concentration of IP-10 in patients with type 2 diabetes mellitus]
    Honglan Xu
    Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan
    Nihon Jinzo Gakkai Shi 47:524-30. 2005
    ..05, respectively) in consistent with previous reports. These results suggested that IP-10 may have an etiopathogenic role in type2 DM and diabetic nephropathy as one of the downstream effectors of proinflammatory cytokines...
  18. ncbi request reprint Eicosapentaenoic acid improves glycemic control in elderly bedridden patients with type 2 diabetes
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
    Tohoku J Exp Med 231:63-74. 2013
    ..EPA/DHA-rich diet might improve glucose metabolism in elderly type 2 diabetic patients on a liquid diet. This phenomenon may be due to the improved insulin resistance mediated by the rise in serum EPA concentrations. ..
  19. pmc Effects of the Great East Japan Earthquake and huge tsunami on glycaemic control and blood pressure in patients with diabetes mellitus
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, Sendai, Japan
    BMJ Open 2:e000830. 2012
    ..To examine the effects of a huge tsunami resulting from the Great East Japan Earthquake on blood pressure (BP) control and glycaemic control in diabetic patients...
  20. doi request reprint Characteristics of the antibodies of two patients who developed daytime hyperglycemia and morning hypoglycemia because of insulin antibodies
    Tsuneo Ishizuka
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University School of Medicine, 1 1 Seiryo cho, Aoba ku, Sendai 980 8574, Japan
    Diabetes Res Clin Pract 84:e21-3. 2009
    ....
  21. ncbi request reprint Regulation of cytochrome P-450 4A activity by peroxisome proliferator-activated receptors in the rat kidney
    Tsuneo Ishizuka
    Department of Nephrology, Endocrinology, and Hypertension, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 26:929-36. 2003
    ....
  22. ncbi request reprint Plasma BNP levels in the treatment of type 2 diabetes with pioglitazone
    Susumu Ogawa
    Division of Nephrology, Endocrinology and Vascular Biology, Tohoku University Graduate School of Medicine, Sendai 980 8574, Japan
    J Clin Endocrinol Metab 88:3993-6. 2003
    ..In conclusion, BNP levels are suggested to be a good marker of Pio-induced LVD, and the Pio treatment of DM2 patients with BNP levels above the normal limit should be carefully carried out by monitoring BNP levels...
  23. pmc Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic Nephropathy
    Susumu Ogawa
    Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Japan
    Biomark Insights 4:97-102. 2009
    ....
  24. ncbi request reprint Beneficial role of tolvaptan in the control of body fluids without reductions in residual renal function in patients undergoing peritoneal dialysis
    Takefumi Mori
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Adv Perit Dial 29:33-7. 2013
    ..Hence, tolvaptan could be a beneficial tool for the control of body fluid and maintenance of RRF in PD patients...