Kaijun Niu

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. pdf Home blood pressure is associated with depressive symptoms in an elderly population aged 70 years and over: a population-based, cross-sectional analysis
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 31:409-16. 2008
  2. ncbi request reprint Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Clin Nutr 84:223-9. 2006
  3. doi request reprint Green tea consumption is associated with depressive symptoms in the elderly
    Kaijun Niu
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
    Am J Clin Nutr 90:1615-22. 2009
  4. doi request reprint Serum C-reactive protein even at very low (<1.0 mg/l) concentration is associated with physical performance in a community-based elderly population aged 70 years and over
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
    Gerontology 54:260-7. 2008
  5. ncbi request reprint Influence of leisure-time physical activity on the relationship between C-reactive protein and hypertension in a community-based elderly population of Japan: the Tsurugaya project
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 28:747-54. 2005
  6. doi request reprint The predictive power of physical function assessed by questionnaire and physical performance measures for subsequent disability
    Masayuki Hoshi
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Seiryo machi, Aobaku, Sendai, Japan
    Aging Clin Exp Res 24:345-53. 2012
  7. doi request reprint Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells
    Mutsuo Yamaya
    Dept of Advanced Preventive Medicine for Infectious Disease, Tohoku Univ School of Medicine, Seiryo machi, Aoba ku, Sendai, Japan
    Am J Physiol Lung Cell Mol Physiol 299:L160-8. 2010
  8. doi request reprint C-reactive protein (CRP) is a predictor of high medical-care expenditures in a community-based elderly population aged 70 years and over: the Tsurugaya project
    Kaijun Niu
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
    Arch Gerontol Geriatr 54:e392-7. 2012
  9. doi request reprint Adiponectin pathway attenuates malignant mesothelioma cell growth
    Kaijun Niu
    Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
    Am J Respir Cell Mol Biol 46:515-23. 2012
  10. pmc Dietary patterns associated with fall-related fracture in elderly Japanese: a population based prospective study
    Yasutake Monma
    Center for Asian Traditional Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    BMC Geriatr 10:31. 2010

Detail Information

Publications44

  1. pdf Home blood pressure is associated with depressive symptoms in an elderly population aged 70 years and over: a population-based, cross-sectional analysis
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 31:409-16. 2008
    ..Further study is required to clarify the causality of this relationship...
  2. ncbi request reprint Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Clin Nutr 84:223-9. 2006
    ..Therefore, it is still unclear whether a greater consumption of n-3 PUFAs is associated with lower serum CRP concentrations...
  3. doi request reprint Green tea consumption is associated with depressive symptoms in the elderly
    Kaijun Niu
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
    Am J Clin Nutr 90:1615-22. 2009
    ..Although these functions might be associated with the development and progression of depressive symptoms, no studies have investigated the relation between green tea consumption and depressive symptoms in a community-dwelling population...
  4. doi request reprint Serum C-reactive protein even at very low (<1.0 mg/l) concentration is associated with physical performance in a community-based elderly population aged 70 years and over
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
    Gerontology 54:260-7. 2008
    ..Therefore, it is still unclear whether a lower CRP is favorably associated with physical performance even within a very low range...
  5. ncbi request reprint Influence of leisure-time physical activity on the relationship between C-reactive protein and hypertension in a community-based elderly population of Japan: the Tsurugaya project
    Kaijun Niu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 28:747-54. 2005
    ..This is the first study to clarify that the positive significant relation between CRP and hypertension was independent of LTPA levels among Japanese elderly...
  6. doi request reprint The predictive power of physical function assessed by questionnaire and physical performance measures for subsequent disability
    Masayuki Hoshi
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Seiryo machi, Aobaku, Sendai, Japan
    Aging Clin Exp Res 24:345-53. 2012
    ..To compare the predictive power of physical function assessed by questionnaire and physical performance measures for subsequent disability in community-dwelling elderly persons...
  7. doi request reprint Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells
    Mutsuo Yamaya
    Dept of Advanced Preventive Medicine for Infectious Disease, Tohoku Univ School of Medicine, Seiryo machi, Aoba ku, Sendai, Japan
    Am J Physiol Lung Cell Mol Physiol 299:L160-8. 2010
    ..l-carbocisteine may reduce airway inflammation in influenza virus infection...
  8. doi request reprint C-reactive protein (CRP) is a predictor of high medical-care expenditures in a community-based elderly population aged 70 years and over: the Tsurugaya project
    Kaijun Niu
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
    Arch Gerontol Geriatr 54:e392-7. 2012
    ..Further study is required to clarify whether reducing CRP by intervention is a cost-effective measure...
  9. doi request reprint Adiponectin pathway attenuates malignant mesothelioma cell growth
    Kaijun Niu
    Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
    Am J Respir Cell Mol Biol 46:515-23. 2012
    ..These findings suggest that the induction or supplementation of adiponectin is an important tactic for developing therapeutic strategies against MM...
  10. pmc Dietary patterns associated with fall-related fracture in elderly Japanese: a population based prospective study
    Yasutake Monma
    Center for Asian Traditional Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    BMC Geriatr 10:31. 2010
    ..Therefore we investigated the relationship between dietary patterns and fall-related fractures in the elderly...
  11. doi request reprint Impact of nocturia on bone fracture and mortality in older individuals: a Japanese longitudinal cohort study
    Haruo Nakagawa
    Department of Urology, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Urol 184:1413-8. 2010
    ..We evaluated the association of nocturia with fracture and death in a large, community based sample of Japanese individuals 70 years old or older...
  12. ncbi request reprint Granulocyte colony-stimulating factor promotes tumor angiogenesis via increasing circulating endothelial progenitor cells and Gr1+CD11b+ cells in cancer animal models
    Tatsuma Okazaki
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    Int Immunol 18:1-9. 2006
    ..We conclude that G-CSF promotes tumor growth by activating tumor angiogenesis via increasing circulating EPCs and Gr1+CD11b+ cells in cancer animal models...
  13. doi request reprint A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: a population-based, cross-sectional analysis
    Kaijun Niu
    Department of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin, China
    J Affect Disord 144:165-70. 2013
    ..The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population...
  14. doi request reprint Impact of physical activity and performance on medical care costs among the Japanese elderly
    Guang Yang
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
    Geriatr Gerontol Int 11:157-65. 2011
    ..The aim of this study was to ascertain the impact of PA on medical care expenditure by considering the physical performance in an elderly community-dwelling population...
  15. ncbi request reprint Association between physical activity and urinary incontinence in a community-based elderly population aged 70 years and over
    Akio Kikuchi
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Eur Urol 52:868-74. 2007
    ..The objective of the present study was to evaluate the association between physical activity (PA) levels and urinary incontinence (UI) in a community-based elderly population aged > or =70 yr...
  16. doi request reprint Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade
    Shinsuke Yamanda
    Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Aoba ku, Sendai, Japan
    Blood 113:3631-9. 2009
    ..These results suggest that ephrinB2 plays a crucial role in nonproductive angiogenesis caused by DLL4 blockade...
  17. doi request reprint l-carbocisteine inhibits respiratory syncytial virus infection in human tracheal epithelial cells
    Masanori Asada
    Department of Infectious Disease, Sendai City Hospital, Sendai, Japan
    Respir Physiol Neurobiol 180:112-8. 2012
    ..These findings suggest that l-carbocisteine may inhibit RS virus infection by reducing the expression of ICAM-1. It may also modulate airway inflammation during RS virus infection...
  18. doi request reprint Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells
    Mutsuo Yamaya
    Department of Advanced Preventive Medicine for Infectious Disease, Tohoku University Graduate School of Medicine, Japan
    Eur J Pharmacol 650:431-44. 2011
    ..ICI 118551 also reversed the effects of procaterol on cAMP levels. Procaterol may inhibit rhinovirus infection by reducing ICAM-1 and acidic endosomes as well as modulate airway inflammation in rhinovirus infection...
  19. doi request reprint Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter
    Masanori Asada
    Department of Geriatrics and Gerontology, Tohoku University School of Medicine, Sendai, Japan
    Int J Cancer 123:511-8. 2008
    ..In addition, DAT-/- mice had less D(1)R. Both pharmacological and genetic interruption of D(1)R showed inhibited tumor growth. These results suggest that modulation of the dopaminergic system may contribute to cancer therapy...
  20. pmc A comparison of the effects of unfractionated heparin, dalteparin and danaparoid on vascular endothelial growth factor-induced tumour angiogenesis and heparanase activity
    Hidenori Takahashi
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Aoba ku, Sendai, Japan
    Br J Pharmacol 146:333-43. 2005
    ..Hence, UFH and dalteparin may be more effective than danaparoid at inhibiting cancer progression in DIC patients with solid tumours, due at least in part to their ability to suppress VEGF and heparanase in tumours...
  21. ncbi request reprint Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small-cell lung cancer
    Hiroyasu Yasuda
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi, Aoba ku, Sendai, Japan
    J Clin Oncol 24:688-94. 2006
    ..To investigate the efficacy and safety of nitroglycerin plus vinorelbine and cisplatin in patients with previously untreated stage IIIB/IV non-small-cell lung cancer (NSCLC) as the experimental arm for the next phase III trial...
  22. ncbi request reprint Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma
    Hiroyasu Yasuda
    Department of Translational Clinical Oncology, Kyoto University Graduate School of Medicine, Kyoto, and Department of Internal Medicine, Sendai City Hospital, Sendai, Japan
    Clin Cancer Res 12:6748-57. 2006
    ..The effects and mechanisms of nitroglycerin on the enhancement of chemosensitivity to docetaxel and carboplatin regimen (DCb) in patients with lung adenocarcinoma have not been reported...
  23. pmc Frequent alcohol drinking is associated with lower prevalence of self-reported common cold: a retrospective study
    Eriko Ouchi
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, 980 8575, Japan
    BMC Public Health 12:987. 2012
    ..This study aimed to investigate the association between the amount and frequency of alcohol drinking and the retrospective prevalence of common cold in Japanese men...
  24. pmc An inverted J-shaped association of serum uric acid with muscle strength among Japanese adult men: a cross-sectional study
    Cong Huang
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai 980 8575, Japan
    BMC Musculoskelet Disord 14:258. 2013
    ..The purpose of this study was to examine the association of serum UA concentration with grip strength and leg extension power in adult men...
  25. pmc Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis
    Tatsuma Okazaki
    Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Neoplasia 10:932-9. 2008
    ..Lewis lung carcinoma cells and MCA-induced fibrosarcomas did not express EpoR. These results suggest that Epo accelerates the growth of tumors that lack EpoR expression by promoting tumor angiogenesis...
  26. pmc Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia
    Takae Ebihara
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Aoba ku, Sendai, Japan
    Br J Clin Pharmacol 62:369-71. 2006
    ..To investigate the effect of menthol on swallowing reflex sensitivity in elderly patients with dysphagia...
  27. doi request reprint Intranasal HGF administration ameliorates the physiologic and morphologic changes in lung emphysema
    Ahmed E Hegab
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Aobaku, Sendai, Japan
    Mol Ther 16:1417-26. 2008
    ....
  28. doi request reprint Green tea consumption is associated with lower psychological distress in a general population: the Ohsaki Cohort 2006 Study
    Atsushi Hozawa
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Clin Nutr 90:1390-6. 2009
    ..Although green tea or its constituents might reduce psychological stress, the relation between green tea consumption and psychological distress has not been investigated in a large-scale study...
  29. ncbi request reprint C-reactive protein and peripheral artery disease among Japanese elderly: the Tsurugaya Project
    Atsushi Hozawa
    Department of Public Health and Forensic Medicine, Graduate School of Medicine, Tohoku University, Seiryo machi, Sendai, Japan
    Hypertens Res 27:955-61. 2004
    ..Thus, a high level of CRP is related to a low ankle brachial index among Japanese elderly as well as Western subjects. This is the first study to report the relationship between CRP and low ankle brachial index among Japanese elderly...
  30. pmc Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation
    Masanori Asada
    Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Neoplasia 11:408-17. 2009
    ..These results suggest that regulation of 5-HT and 5-HT receptors, especially the 5-HT(2B) receptor, may serve as a therapeutic strategy in cancer therapy...
  31. doi request reprint Olfactory stimuli and enhanced postural stability in older adults
    Shannon Freeman
    Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Gait Posture 29:658-60. 2009
    ..Decreases in RMS displacements were small and mostly insignificant. The study suggests that olfactory stimulation may improve posture stability in older adults through decreasing the velocities of postural adjustments during normal sway...
  32. doi request reprint Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells
    Masanori Asada
    Department of Geriatrics and Gerontology, Tohoku University School of Medicine, Sendai, Japan
    Antiviral Res 83:191-200. 2009
    ....
  33. pmc Multiplex PCR-identified cutaneous tuberculosis evoked by Mycobacterium bovis BCG vaccination in a healthy baby
    Tatsuma Okazaki
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    J Clin Microbiol 43:523-5. 2005
    ..A healthy baby with a developing abscess is described. A multiplex PCR identified the abscess as originating from M. bovis BCG Tokyo 172...
  34. ncbi request reprint Macrophage colony-stimulating factor induces vascular endothelial growth factor production in skeletal muscle and promotes tumor angiogenesis
    Tatsuma Okazaki
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai, Japan
    J Immunol 174:7531-8. 2005
    ..These results suggest that M-CSF promotes tumor growth by increasing endothelial progenitor cells and activating angiogenesis, and the effects of M-CSF are largely based on the induction of systemic VEGF from skeletal muscles...
  35. doi request reprint Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells
    Mutsuo Yamaya
    Department of Advanced Preventive Medicine for Infectious Disease, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku 980 8575, Japan
    J Pharmacol Exp Ther 333:81-90. 2010
    ..Clarithromycin may modulate airway inflammation in influenza virus infection...
  36. doi request reprint Coffee treatment prevents the progression of sarcopenia in aged mice in vivo and in vitro
    Yinting Guo
    Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin, China Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Exp Gerontol 50:1-8. 2014
    ..These findings suggest that the coffee treatment had a beneficial effect on age-related sarcopenia. ..
  37. ncbi request reprint [Prevention of decline in subjectively perceived physical function of the elderly by regular participation in a community-based exercise group]
    Tomomi Gotou
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine
    Nihon Ronen Igakkai Zasshi 47:601-10. 2010
    ..The objective of this study was to evaluate the effect of a community-based group exercise program on physical functioning among elderly people...
  38. pmc Skin advanced glycation end product accumulation and muscle strength among adult men
    Haruki Momma
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
    Eur J Appl Physiol 111:1545-52. 2011
    ..A long-term prospective study is required to clarify the causality...
  39. pmc Macrophage colony-stimulating factor improves cardiac function after ischemic injury by inducing vascular endothelial growth factor production and survival of cardiomyocytes
    Tatsuma Okazaki
    Department of Geriatrics and Gerontology, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    Am J Pathol 171:1093-103. 2007
    ..These results suggest M-CSF might be a novel therapeutic agent for ischemic heart disease...
  40. ncbi request reprint [Effectiveness of ability grouping in structured fall prevention exercise program for frail elderly people]
    Hidenori Yano
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine
    Nihon Ronen Igakkai Zasshi 43:390-7. 2006
    ..To assess the effectiveness of ability grouping in a fall prevention structured exercise program for elderly people...
  41. ncbi request reprint Increased arterial carboxyhemoglobin concentrations in chronic obstructive pulmonary disease
    Hiroyasu Yasuda
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai, 980 8574, Japan
    Am J Respir Crit Care Med 171:1246-51. 2005
    ..Exhaled carbon monoxide (CO) and arterial blood carboxyhemoglobin concentrations (Hb-CO) increase in inflammatory pulmonary diseases...
  42. doi request reprint Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study
    Kaijun Niu
    Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, 2 1 Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
    J Bone Miner Metab 28:568-77. 2010
    ..These finding suggested that office-based brief HIE can be recommended for premenopausal women for preventing bone mineral loss...
  43. ncbi request reprint A pilot study of banxia houpu tang, a traditional Chinese medicine, for reducing pneumonia risk in older adults with dementia
    Koh Iwasaki
    Center for Asian Traditional Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan
    J Am Geriatr Soc 55:2035-40. 2007
    ..To evaluate whether the traditional Chinese herbal medicine banxia houpu tang (BHT, formula magnolia et pinelliae) prevents aspiration pneumonia and pneumonia-related mortality in elderly people...
  44. ncbi request reprint Daily oral care and cough reflex sensitivity in elderly nursing home patients
    Aya Watando
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    Chest 126:1066-70. 2004
    ..Intensive oral care can reduce the incidence of pneumonia in elderly nursing home patients, but the mechanism is unknown...