Eiji Nemoto


Affiliation: Tohoku University
Country: Japan


  1. Sakisaka Y, Tsuchiya M, Nakamura T, Tamura M, Shimauchi H, Nemoto E. Wnt5a attenuates Wnt3a-induced alkaline phosphatase expression in dental follicle cells. Exp Cell Res. 2015;336:85-93 pubmed publisher
    ..These findings suggest the existence of a feedback mechanism between canonical and noncanonical Wnt signaling during the differentiation of dental follicle cells. ..
  2. Nemoto E, Ebe Y, Kanaya S, Tsuchiya M, Nakamura T, Tamura M, et al. Wnt5a signaling is a substantial constituent in bone morphogenetic protein-2-mediated osteoblastogenesis. Biochem Biophys Res Commun. 2012;422:627-32 pubmed publisher
    ..Taken together, our results suggest that Wnt5a/Ror2 signaling appears to be involved in BMP-2-mediated osteoblast differentiation in a Smad independent pathway. ..
  3. Nemoto E, Gotoh K, Tsuchiya M, Sakisaka Y, Shimauchi H. Extracellular ATP inhibits IL-1-induced MMP-1 expression through the action of CD39/nucleotidase triphosphate dephosphorylase-1 on human gingival fibroblasts. Int Immunopharmacol. 2013;17:513-8 pubmed publisher
    ..The present findings suggest the existence of an endogenous anti-tissue destructive mechanism in gingival tissue via the CD39-adenosinergic axis. ..
  4. Suzuki R, Nemoto E, Shimauchi H. Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells. Exp Cell Res. 2014;323:232-41 pubmed publisher
  5. Sakisaka Y, Kanaya S, Nakamura T, Tamura M, Shimauchi H, Nemoto E. p38 MAP kinase is required for Wnt3a-mediated osterix expression independently of Wnt-LRP5/6-GSK3? signaling axis in dental follicle cells. Biochem Biophys Res Commun. 2016;478:527-32 pubmed publisher
    ..These findings expand our knowledge of the mechanisms controlling periodontal development and regeneration. ..