N Kimura

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. ncbi Immunohistochemical expression of chromogranins A and B, prohormone convertases 2 and 3, and amidating enzyme in carcinoid tumors and pancreatic endocrine tumors
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, Tohoku Rosai Hospital, Sendai, Japan
    Mod Pathol 13:140-6. 2000
  2. ncbi Immunohistochemical expression of somatostatin type 2A receptor in neuroendocrine tumors
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, and Tohoku Rosai Hospital, Sendai, Japan
    Clin Cancer Res 5:3483-7. 1999
  3. ncbi HMB-45 and tuberin in hamartomas associated with tuberous sclerosis
    N Kimura
    Department of Histopathology, Tohoku University School of Medicine, Sendai, Japan
    Mod Pathol 10:952-9. 1997
  4. ncbi Angiodestruction and tissue necrosis of skin-involving CD56+ NK/T-cell lymphoma are influenced by expression of cell adhesion molecules and cytotoxic granule and apoptosis-related proteins
    M Takeshita
    Department of Pathology, National Kyushu Medical Center Hospital, Fukuoka, Japan
    Am J Clin Pathol 113:201-11. 2000
  5. ncbi Plasma chromogranin A in pheochromocytoma, primary hyperparathyroidism and pituitary adenoma in comparison with catecholamine, parathyroid hormone and pituitary hormones
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Endocr J 44:319-27. 1997
  6. ncbi Immunohistochemical localization of somatostatin receptor type 2A in rat and human tissues
    N Kimura
    Department of Pathology and Laboratory Medicine, Tohoku Rosai Hospital, Sendai, Japan
    Endocr J 48:95-102. 2001
  7. ncbi The loss of E-cadherin, alpha- and beta-catenin expression is associated with metastasis and poor prognosis in invasive breast cancer
    R Yoshida
    Department of Surgical Oncology, Tohoku University School of Medicine, Sendai, Japan
    Int J Oncol 18:513-20. 2001
  8. ncbi Cases of cutaneous and nasal CD56 (NCAM)-positive lymphoma in Japan have differences in immunohistology, genotype, and etiology
    M Takeshita
    Department of Pathology, National Kyushu Medical Center Hospital, Fukuoka, Japan
    Hum Pathol 30:1024-34. 1999
  9. pmc Expression of platelet-derived endothelial cell growth factor and its potential role in up-regulation of angiogenesis in scarred kidneys secondary to urinary tract diseases
    R Konda
    Department of Urology, Tohoku University School of Medicine, Sendai, Japan
    Am J Pathol 155:1587-97. 1999
  10. ncbi Genotype analysis of prepro-vasopressin signal peptide in vasopressin-producing and -non-producing lung tumors
    M Shoji
    The Second Department of Internal Medicine, Tohoku University, Sendai, Japan
    Life Sci 61:2561-6. 1997

Detail Information

Publications19

  1. ncbi Immunohistochemical expression of chromogranins A and B, prohormone convertases 2 and 3, and amidating enzyme in carcinoid tumors and pancreatic endocrine tumors
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, Tohoku Rosai Hospital, Sendai, Japan
    Mod Pathol 13:140-6. 2000
    ..In conclusion, expression of CgA and CgB was different depending on the tumor location. High frequency of PCs and PGM may explain why even nonfunctioning tumors produce some inconspicuous peptides...
  2. ncbi Immunohistochemical expression of somatostatin type 2A receptor in neuroendocrine tumors
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, and Tohoku Rosai Hospital, Sendai, Japan
    Clin Cancer Res 5:3483-7. 1999
    ....
  3. ncbi HMB-45 and tuberin in hamartomas associated with tuberous sclerosis
    N Kimura
    Department of Histopathology, Tohoku University School of Medicine, Sendai, Japan
    Mod Pathol 10:952-9. 1997
    ....
  4. ncbi Angiodestruction and tissue necrosis of skin-involving CD56+ NK/T-cell lymphoma are influenced by expression of cell adhesion molecules and cytotoxic granule and apoptosis-related proteins
    M Takeshita
    Department of Pathology, National Kyushu Medical Center Hospital, Fukuoka, Japan
    Am J Clin Pathol 113:201-11. 2000
    ..CAMs and the 3 cytotoxic granule proteins and an apoptosis pathway might be important factors in the paracrine and autocrine mechanisms of tissue necrosis in cutaneous CD56+ NK/T cell lymphoma...
  5. ncbi Plasma chromogranin A in pheochromocytoma, primary hyperparathyroidism and pituitary adenoma in comparison with catecholamine, parathyroid hormone and pituitary hormones
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Endocr J 44:319-27. 1997
    ..Plasma CgA is a useful tumor marker for pheochromocytoma, even for malignant pheochromocytoma without elevated CA level, but not for hyperparathyroidism, or pituitary adenoma...
  6. ncbi Immunohistochemical localization of somatostatin receptor type 2A in rat and human tissues
    N Kimura
    Department of Pathology and Laboratory Medicine, Tohoku Rosai Hospital, Sendai, Japan
    Endocr J 48:95-102. 2001
    ..In the kidney, the glomerular capillaries and collecting tubules, but not proximal tubules, showed immunoreactivity. SSTR2A immunoreactivity was observed not only in endocrine cells but also in non-endocrine cells...
  7. ncbi The loss of E-cadherin, alpha- and beta-catenin expression is associated with metastasis and poor prognosis in invasive breast cancer
    R Yoshida
    Department of Surgical Oncology, Tohoku University School of Medicine, Sendai, Japan
    Int J Oncol 18:513-20. 2001
    ..Reduction or loss of E-cadherin and catenin expression may be associated with distant and lymph node metastases in invasive breast cancer, and the heterogeneous type may be associated with poor prognosis...
  8. ncbi Cases of cutaneous and nasal CD56 (NCAM)-positive lymphoma in Japan have differences in immunohistology, genotype, and etiology
    M Takeshita
    Department of Pathology, National Kyushu Medical Center Hospital, Fukuoka, Japan
    Hum Pathol 30:1024-34. 1999
    ..Thus, two types of cutaneous CD56-positive lymphoma were found, each having a unique cell characteristic, genotype, and EBV infection pattern that differed from that of nasal-type lymphoma...
  9. pmc Expression of platelet-derived endothelial cell growth factor and its potential role in up-regulation of angiogenesis in scarred kidneys secondary to urinary tract diseases
    R Konda
    Department of Urology, Tohoku University School of Medicine, Sendai, Japan
    Am J Pathol 155:1587-97. 1999
    ..These results suggest that angiogenesis may play a critical role in the progression of tubulointerstitial injuries and that up-regulation of PD-ECGF may contribute to neovascularization...
  10. ncbi Genotype analysis of prepro-vasopressin signal peptide in vasopressin-producing and -non-producing lung tumors
    M Shoji
    The Second Department of Internal Medicine, Tohoku University, Sendai, Japan
    Life Sci 61:2561-6. 1997
    ..These results suggest that similar to the hypothalamus the normal signal peptide is functional in tumor cells and that the variant signal peptide is not a prerequisite for AVP secretion from SCLC cells...
  11. ncbi Immunohistochemical expression of gonadotropin releasing hormone receptor in human breast carcinoma
    T Moriya
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Pathol Int 51:333-7. 2001
    ..Breast carcinomas positive for GnRH-R maintain some hormonal regulatory mechanisms, and GnRH actions may lead to a low proliferative rate in human breast carcinoma...
  12. ncbi Müller cells in developing rats with inherited retinal dystrophy
    N Kimura
    Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan
    Tohoku J Exp Med 191:157-66. 2000
    ..Müller cells might be affected following the progressive degeneration of photoreceptor cells and react to the glio-neuronal relationship...
  13. ncbi Immunohistochemical study of Muc1, Muc2 and human gastric mucin in breast carcinoma: relationship with prognostic factors
    Y Xu
    Department of Pathology, Tohoku Rosai Hospital, Sendai, Japan
    Oncol Rep 8:1177-82. 2001
    ..Muc 2 expression correlated with lymph node metastasis. HGM was found in the tumors without lymph node metastasis and lower levels of serum CA153...
  14. ncbi Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues
    N Kimura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    J Histochem Cytochem 41:671-8. 1993
    ..Cells immunoreactive for AR were ubiquitously distributed throughout the entire body. The present study demonstrated the diversity of androgen effects on many target tissues...
  15. ncbi Demonstration of neuroendocrine cells in ovarian mucinous tumors
    E Sasaki
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
    Int J Gynecol Pathol 8:189-200. 1989
    ..Based on the high frequency of endocrine cells, borderline tumors seemed to be unique in the spectrum of mucinous ovarian tumors...
  16. ncbi Twenty-six-years' survival with multiple bone metastasis of malignant pheochromocytoma
    S Yoshida
    Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan
    Arch Orthop Trauma Surg 121:598-600. 2001
    ..The metastatic lesion in the ilium was left untouched. After 26 years, she is well despite a recurrence of the tumors in the skull and a new metastasis in the left abdomen...
  17. ncbi Synaptotagmin I expression in mast cells of normal human tissues, systemic mast cell disease, and a human mast cell leukemia cell line
    N Kimura
    Department of Pathology, Second Department of Internal Medicine, First Department of Pharmacology, Tohoku University, Sendai, Japan
    J Histochem Cytochem 49:341-6. 2001
    ..STG I immunoreactivity was weaker than NB-1 or PC12 immunoreactivity. However, it increased in the stimulated HMC-1 cells. Mast cells expressed STG I in various states. STG I may mediate exocytosis of large granules in mast cells...
  18. ncbi Decreased sensitivity of distal nephron and collecting duct to parathyroid hormone in pseudohypoparathyroidism type I
    M Goto
    Miyagi Social Insurance Hospital, Sendai, Japan
    J Am Soc Nephrol 12:1965-70. 2001
    ..These observations suggest that the preservation of renal tubular sensitivity to PTH in this disorder may be confined to PTH-dependent calcium resorption in distal tubules...
  19. ncbi Renin containing cells are present predominantly in scarred areas but not in dysplastic regions in multicystic dysplastic kidney
    R Konda
    Department of Urology, Tohoku University School of Medicine, Sendai, Japan
    J Urol 166:1910-4. 2001
    ..Renin producing cells in the juxtaglomerular apparatus of mature glomeruli and interlobular arteries in the scarred areas may be the predominant source of renin production in this organ...