Shin Fukudo

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. pmc Effects of personality traits on the manifestations of irritable bowel syndrome
    Jun Tayama
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Tohoku, Japan
    Biopsychosoc Med 6:20. 2012
  2. doi request reprint Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: a randomized, placebo-controlled and dose-finding study
    S Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Neurogastroenterol Motil 23:544-e205. 2011
  3. doi request reprint Gene, environment, and brain-gut interactions in irritable bowel syndrome
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Aoba, Sendai, Japan
    J Gastroenterol Hepatol 26:110-5. 2011
  4. doi request reprint Neural substrates of decision making as measured with the Iowa Gambling Task in men with alexithymia
    Michiko Kano
    Tohoku University Graduate School of Medicine, Japan
    Psychosom Med 73:588-97. 2011
  5. ncbi request reprint Personality and body mass index: a cross-sectional analysis from the Miyagi Cohort Study
    Masako Kakizaki
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Seiryo machi, Aoba ku, Sendai, Miyagi, Japan
    J Psychosom Res 64:71-80. 2008
  6. doi request reprint Serotonin transporter gene promoter polymorphism and alexithymia
    Michiko Kano
    Department of Behavioral Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan
    Neuropsychobiology 65:76-82. 2012
  7. ncbi request reprint Corticotropin-releasing hormone receptor 1 antagonist blocks brain-gut activation induced by colonic distention in rats
    Kumi Saito
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Gastroenterology 129:1533-43. 2005
  8. pmc Corticotropin-releasing hormone receptor 1 gene variants in irritable bowel syndrome
    Naoko Sato
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 7:e42450. 2012
  9. doi request reprint Effect of autogenic training on general improvement in patients with irritable bowel syndrome: a randomized controlled trial
    Masae Shinozaki
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai, 980 8575, Japan
    Appl Psychophysiol Biofeedback 35:189-98. 2010
  10. ncbi request reprint Alcohol consumption and mortality in Japan: the Miyagi Cohort Study
    Naoki Nakaya
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980 8575, Japan
    J Epidemiol 14:S18-25. 2004

Collaborators

Detail Information

Publications47

  1. pmc Effects of personality traits on the manifestations of irritable bowel syndrome
    Jun Tayama
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Tohoku, Japan
    Biopsychosoc Med 6:20. 2012
    ..abstract:..
  2. doi request reprint Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: a randomized, placebo-controlled and dose-finding study
    S Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Neurogastroenterol Motil 23:544-e205. 2011
    ..The aim of this work was to perform a dose-finding study for lubiprostone for the treatment of constipation with or without irritable bowel syndrome (IBS) in Japan...
  3. doi request reprint Gene, environment, and brain-gut interactions in irritable bowel syndrome
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Aoba, Sendai, Japan
    J Gastroenterol Hepatol 26:110-5. 2011
    ..In conclusion, gene x environment interaction together with brain-gut interactions may play crucial roles in IBS development. Further fundamental research on this issue is warranted...
  4. doi request reprint Neural substrates of decision making as measured with the Iowa Gambling Task in men with alexithymia
    Michiko Kano
    Tohoku University Graduate School of Medicine, Japan
    Psychosom Med 73:588-97. 2011
    ....
  5. ncbi request reprint Personality and body mass index: a cross-sectional analysis from the Miyagi Cohort Study
    Masako Kakizaki
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Seiryo machi, Aoba ku, Sendai, Miyagi, Japan
    J Psychosom Res 64:71-80. 2008
    ....
  6. doi request reprint Serotonin transporter gene promoter polymorphism and alexithymia
    Michiko Kano
    Department of Behavioral Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan
    Neuropsychobiology 65:76-82. 2012
    ..We investigated the possibility that polymorphism of the 5-HT transporter-linked promoter region (5-HTTLPR) is associated with alexithymia...
  7. ncbi request reprint Corticotropin-releasing hormone receptor 1 antagonist blocks brain-gut activation induced by colonic distention in rats
    Kumi Saito
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Gastroenterology 129:1533-43. 2005
    ..We also investigated whether pretreatment with JTC-017 blocks acute or chronic colorectal distention-induced adrenocorticotropic hormone release, anxiety, and stress-induced changes in colonic motility...
  8. pmc Corticotropin-releasing hormone receptor 1 gene variants in irritable bowel syndrome
    Naoko Sato
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 7:e42450. 2012
    ..We tested the hypothesis that genetic polymorphisms and haplotypes of CRH-R1 moderate the IBS phenotype and negative emotion in IBS patients...
  9. doi request reprint Effect of autogenic training on general improvement in patients with irritable bowel syndrome: a randomized controlled trial
    Masae Shinozaki
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai, 980 8575, Japan
    Appl Psychophysiol Biofeedback 35:189-98. 2010
    ..05) as compared to the control group. Role emotional (p = 0.051) and general health (p = 0.068) showed a tendency for improvement in the AT group. AT may be useful in the treatment of IBS by enhancing self-control...
  10. ncbi request reprint Alcohol consumption and mortality in Japan: the Miyagi Cohort Study
    Naoki Nakaya
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980 8575, Japan
    J Epidemiol 14:S18-25. 2004
    ..We examined the association between alcohol consumption and all-cause mortality in Japanese men and women...
  11. doi request reprint Altered cognitive function of prefrontal cortex during error feedback in patients with irritable bowel syndrome, based on FMRI and dynamic causal modeling
    Emiko Aizawa
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Gastroenterology 143:1188-98. 2012
    ..We investigated whether they have latent impairments in cognitive flexibility because of dysfunction in the DLPFC and insula and altered connectivity between brain regions...
  12. ncbi request reprint Validation of the Japanese version of the Rome II modular questionnaire and irritable bowel syndrome severity index
    Masae Shinozaki
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Seiryo, Aoba, Sendai, Japan
    J Gastroenterol 41:491-4. 2006
    ..The aim of this study was to develop, validate, and confirm the reliability of the Japanese version of the Rome II modular questionnaire for IBS (RIIMQ-J) and the IBS severity index (IBSSI-J)...
  13. doi request reprint Brain activation associated with changes in heart rate, heart rate variability, and plasma catecholamines during rectal distention
    Hideaki Suzuki
    Department of Behavioral Medicine, Tohoku University, Aoba, Sendai, Japan
    Psychosom Med 71:619-26. 2009
    ..How the human brain processes interoceptive signals and forms initial autonomic arousal is one of the key questions to be answered in research on emotion...
  14. doi request reprint High prevalence of irritable bowel syndrome in medical outpatients in Japan
    Masae Shinozaki
    Tohoku University, Aoba, Sendai, Japan
    J Clin Gastroenterol 42:1010-6. 2008
    ..We tested the hypotheses that the prevalence of IBS in medical outpatients clinics in Japan is high, and that IBS patients feel more psychosocial stress than patients without IBS...
  15. ncbi request reprint Preliminary study: psychological effects of muscle relaxation on juvenile delinquents
    Naoki Nakaya
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Int J Behav Med 11:176-80. 2004
    ..1, P=0.007). There were no significant interactions in the other psychological subscales. Thus, muscle relaxation therapy may improve frustration tolerance among juvenile delinquents...
  16. ncbi request reprint Validation of the Japanese version of comorbid conditions questionnaire (CCQ-J) and recent physical symptoms questionnaire (RPSQ-J)
    Masae Shinozaki
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Japan
    Intern Med 50:375-80. 2011
    ..The purpose of this study was to validate the Japanese versions created, the CCQ-J and RPSQ-J...
  17. pmc Neural basis of impaired cognitive flexibility in patients with anorexia nervosa
    Yasuhiro Sato
    Department of Psychosomatic Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
    PLoS ONE 8:e61108. 2013
    ....
  18. ncbi request reprint Personality and mortality from ischemic heart disease and stroke
    Naoki Nakaya
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Clin Exp Hypertens 27:297-305. 2005
    ..The role of personality in the causation of circulatory diseases has been controversial...
  19. doi request reprint Long sleep duration and cause-specific mortality according to physical function and self-rated health: the Ohsaki Cohort Study
    Masako Kakizaki
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Sleep Res 22:209-16. 2013
    ..We conclude that, with the exception of stroke mortality, the association between long sleep duration and mortality is not modified by physical function or health status...
  20. doi request reprint Visceral hypersensitivity in irritable bowel syndrome
    Motoyori Kanazawa
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Gastroenterol Hepatol 26:119-21. 2011
    ..In conclusion, visceral hypersensitivity is common in IBS patients and probably plays a major role in development of the symptoms and both central and peripheral factors may enhance the pain sensitivity...
  21. doi request reprint Effect of repetitive transcranial magnetic stimulation on rectal function and emotion in humans
    Yuuichi Aizawa
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai 980 8575, Japan
    J Gastroenterol 46:1071-80. 2011
    ..We hypothesized that functional modulation of the right DLPFC by repetitive transcranial magnetic stimulation (rTMS) can reveal the actual role of right DLPFC in brain-gut interactions in humans...
  22. doi request reprint Effects of preceding stimulation on brain activation in response to colonic distention in humans
    Toyohiro Hamaguchi
    Department of Behavioral Medicine, Graduate School of Medicine, Tohoku University, Aoba, Sendai, Japan
    Psychosom Med 75:453-62. 2013
    ..Nevertheless, how the pattern of stimulation affects sensitization and/or desensitization to visceral stimulation remains unknown...
  23. ncbi request reprint Specific brain processing of facial expressions in people with alexithymia: an H2 15O-PET study
    Michiko Kano
    Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan
    Brain 126:1474-84. 2003
    ....
  24. pmc Brain activity following esophageal acid infusion using positron emission tomography
    Shigeyuki Kobayashi
    Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8574, Japan
    World J Gastroenterol 16:5481-9. 2010
    ..To investigate symptoms and brain activity following esophageal acid infusion...
  25. pmc Enhanced auditory brainstem response and parental bonding style in children with gastrointestinal symptoms
    Shizuka Seino
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    PLoS ONE 7:e32913. 2012
    ..We hypothesized that children with chronic gastrointestinal (GI) symptoms like IBS may show exaggerated brainstem auditory evoked potential (BAEP) responses and receive more inadequate parental bonding...
  26. ncbi request reprint Brain responses to cardiac electrical stimulation: a new EEG method for evaluating cardiac sensation
    Hideaki Suzuki
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Tohoku J Exp Med 226:3-10. 2012
    ..This new method should be useful for examining pathophysiology of cardiac diseases with pathological cardiac sensation, including cardiac anxiety and silent myocardial ischemia...
  27. ncbi request reprint Relationship of health status and social support to the life satisfaction of older adults
    Chih Wen Wang
    Department of Rehabilitation Medicine for People with Physical Disability, Tohoku University Graduate School of Medicine, Tohoku University Graduate School of Medicine, Sendai 980 8575, Japan
    Tohoku J Exp Med 198:141-9. 2002
    ..When preparing health promotion strategies for older adults, results of gender differences as they related to social support and life satisfaction should be applied in practice...
  28. ncbi request reprint Can personality traits predict pathological responses to audiovisual stimulation?
    Tomoyuki Yambe
    Department of Medical Engineering and Cardiology, Institute of Development, Aging and Cancer, Tohoku University, 4 1 Seiryo machi, Aoba ku, Sendai 980 stH5, Japan
    Biomed Pharmacother 57:83s-86s. 2003
    ..By examining such directivity, it is expected that subjects, which show morbid reaction to an audiovisual stimulation, can be screened beforehand...
  29. doi request reprint The features of adolescent irritable bowel syndrome in Japan
    Yuka Endo
    Department of Psychosomatic Medicine, Tohoku University Hospital, Japan
    J Gastroenterol Hepatol 26:106-9. 2011
    ..The onset of IBS is in adolescence in many cases. However, the features of adolescent IBS were generally lacking. The objective of this research was to know the features of adolescent IBS in Japan...
  30. ncbi request reprint [Development of neuroimaging research on human emotion]
    Manabu Tashiro
    Nihon Yakurigaku Zasshi 125:88-96. 2005
  31. ncbi request reprint Exaggerated motility of the descending colon with repetitive distention of the sigmoid colon in patients with irritable bowel syndrome
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai 980 8575, Japan
    J Gastroenterol 37:145-50. 2002
    ..e., altered bowel habit with abdominal pain relieved by defecation. We tested our hypothesis that an abnormal link between luminal stimulation and mural response may have some role in the pathophysiology of IBS...
  32. ncbi request reprint Role of corticotropin-releasing hormone in irritable bowel syndrome and intestinal inflammation
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai, 980 8575, Japan
    J Gastroenterol 42:48-51. 2007
    ..These findings suggest the major role of CRH in stress-related pathophysiology of IBS and possibly in inflammation of the intestinal mucosa...
  33. ncbi request reprint Gender difference in association between polymorphism of serotonin transporter gene regulatory region and anxiety
    Tomoko Mizuno
    Tohoku University Graduate School of Medicine, Sendai, Japan
    J Psychosom Res 60:91-7. 2006
    ..The objective of this study was to verify the hypothesis that variation of the serotonin transporter gene promoter region (5-HTTLPR) is associated with sensitivity to stress...
  34. ncbi request reprint [Effects of gender on irritable bowel syndrome]
    Tomomi Hattori
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
    Nihon Rinsho 64:1549-51. 2006
    ..It is also indicated that males with IBS have greater sympathovagal balance in response to visceral stimulation. Further elucidation of gender differences in IBS may contribute to treatment of IBS...
  35. ncbi request reprint Effects of fasting therapy on irritable bowel syndrome
    Motoyori Kanazawa
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Int J Behav Med 13:214-20. 2006
    ..03), abdominal distension (p < .01), and interference with life (p = .01). Our results suggest that FT may have beneficial effects on intractable patients with IBS...
  36. ncbi request reprint Laterality and imbalance of muscle stiffness relate to personality
    Naoki Nakaya
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Behav Med 30:5-9. 2004
    ..The findings suggest that laterality and imbalance of muscle stiffness relate to personality...
  37. ncbi request reprint [Epidemiological studies in irritable bowel syndrome]
    Motoyori Kanazawa
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
    Nihon Rinsho 64:1420-4. 2006
    ..It should be necessary to know these diverse aspects of such 'difficult' patients with IBS considering a bio- psycho- social model in clinical practice...
  38. ncbi request reprint Abnormal relationship between dissociation and hypnotic susceptibility in irritable bowel syndrome
    Satoshi Watanabe
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
    Scand J Gastroenterol 41:757-8. 2006
  39. ncbi request reprint [Use of Rome III criteria for diagnosing irritable bowel syndrome]
    Tomomi Hattori
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
    Nihon Rinsho 64:1425-8. 2006
    ..Besides, Rome III criteria was recently published. Because IBS is a frequent disease, the spread of Rome III criteria will play an important role of pathophysiological study and new therapy in gastrointestinal medical care...
  40. pmc Biopsychosocial model of irritable bowel syndrome
    Yukari Tanaka
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Neurogastroenterol Motil 17:131-9. 2011
    ....
  41. pmc The alexithymic brain: the neural pathways linking alexithymia to physical disorders
    Michiko Kano
    Behavioral Medicine, Tohoku University Graduate School of Medicine, Tohoku University, 2 1 Seiryo cho, Aoba ku, Sendai, 980 8575, Japan
    Biopsychosoc Med 7:1. 2013
    ..Deficient development of emotional neural structures may lead to hypersensitivity to bodily sensations and unhealthy behaviors, a possible mechanism linking alexithymia to psychosomatic disorders...
  42. doi request reprint Management and pathophysiology of functional gastrointestinal disorders
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan
    Digestion 85:85-9. 2012
    ....
  43. ncbi request reprint Colorectal distention induces hippocampal noradrenaline release in rats: an in vivo microdialysis study
    Kumi Saito
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
    Brain Res 947:146-9. 2002
    ..Abdominal contractions were induced only by colorectal distention. Our results suggest that noradrenaline levels increase in the hippocampus under colorectal distention and this may relate to behavioral changes...
  44. ncbi request reprint [Brain-gut interactions]
    Tomomi Hattori
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
    Nihon Rinsho 64:1406-8. 2006
  45. ncbi request reprint Personality and the risk of cancer
    Naoki Nakaya
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Natl Cancer Inst 95:799-805. 2003
    ..The role of personality in the causation of cancer has been controversial. We examined this question in a large, prospective study...
  46. ncbi request reprint [Epidemiological data of irritable bowel syndrome]
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
    Nihon Rinsho 60:179-85. 2002
  47. ncbi request reprint Clinical significance of blood pressure response triggered by a doctor's visit in patients with essential hypertension
    Masanori Munakata
    Division of Hypertension and Cardiology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Hypertens Res 25:343-9. 2002
    ..003, p=0.05). These data suggest that the pressor response triggered by a doctor's visit has clinical significance in never-before treated hypertensive patients, possibly because it mirrors real-life stress reactivity in men...