Shinji Deguchi

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. pmc Mechanism of and threshold biomechanical conditions for falsetto voice onset
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Aramaki Aoba, Sendai, Japan
    PLoS ONE 6:e17503. 2011
  2. doi Cooperative regulation of vocal fold morphology and stress by the cricothyroid and thyroarytenoid muscles
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    J Voice 25:e255-63. 2011
  3. doi Simultaneous contraction and buckling of stress fibers in individual cells
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    J Cell Biochem 113:824-32. 2012
  4. doi The position and size of individual focal adhesions are determined by intracellular stress-dependent positive regulation
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    Cytoskeleton (Hoboken) 68:639-51. 2011
  5. doi Measurement and finite element modeling of the force balance in the vertical section of adhering vascular endothelial cells
    Shinji Deguchi
    CRESS Center for Research Strategy and Support, Tohoku University, 6 6 11 1306 2, Aramaki Aoba, Sendai 980 8579, Japan
    J Mech Behav Biomed Mater 2:173-85. 2009
  6. doi Theoretical consideration of the flow behavior in oscillating vocal fold
    Shinji Deguchi
    Graduate School of Biomedical Engineering, Tohoku University, 6 6 11 1306 2 Aramaki Aoba, Sendai 980 8579, Japan
    J Biomech 42:824-9. 2009
  7. doi A versatile micro-mechanical tester for actin stress fibers isolated from cells
    Tsubasa S Matsui
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Sendai, Japan
    Biorheology 46:401-15. 2009
  8. ncbi Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells
    Shinji Deguchi
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Sendai 9808579, Japan
    J Biomech 39:2603-10. 2006
  9. ncbi Computer-aided technique for automatic determination of the relationship between transglottal pressure change and voice fundamental frequency
    Shinji Deguchi
    Center for Research Strategy and Support, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan
    Ann Otol Rhinol Laryngol 117:876-80. 2008
  10. doi Actin stress fibers are at a tipping point between conventional shortening and rapid disassembly at physiological levels of MgATP
    Tsubasa S Matsui
    Department of Biomedical Engineering, Tohoku University, Japan
    Biochem Biophys Res Commun 395:301-6. 2010

Collaborators

Detail Information

Publications15

  1. pmc Mechanism of and threshold biomechanical conditions for falsetto voice onset
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Aramaki Aoba, Sendai, Japan
    PLoS ONE 6:e17503. 2011
    ..Understanding of the voice onset mechanism and the explicit mathematical descriptions of thresholds would be beneficial for the diagnosis and treatment of voice diseases and the development of artificial vocal folds...
  2. doi Cooperative regulation of vocal fold morphology and stress by the cricothyroid and thyroarytenoid muscles
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    J Voice 25:e255-63. 2011
    ..Thus, the present analyses demonstrate quantitative relationships between the two muscles in their cooperative regulation of vocal fold morphology and stress...
  3. doi Simultaneous contraction and buckling of stress fibers in individual cells
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    J Cell Biochem 113:824-32. 2012
    ....
  4. doi The position and size of individual focal adhesions are determined by intracellular stress-dependent positive regulation
    Shinji Deguchi
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    Cytoskeleton (Hoboken) 68:639-51. 2011
    ..These results suggest that a positive regulation (i.e., force and cell adhesion enhance each other) functions in the organization of individual FAs in nonmigrating cells...
  5. doi Measurement and finite element modeling of the force balance in the vertical section of adhering vascular endothelial cells
    Shinji Deguchi
    CRESS Center for Research Strategy and Support, Tohoku University, 6 6 11 1306 2, Aramaki Aoba, Sendai 980 8579, Japan
    J Mech Behav Biomed Mater 2:173-85. 2009
    ..These results indicate that the nuclear/cytoplasmic mechanical properties and degrees of prestress determine the vertical section structure of adhering cells...
  6. doi Theoretical consideration of the flow behavior in oscillating vocal fold
    Shinji Deguchi
    Graduate School of Biomedical Engineering, Tohoku University, 6 6 11 1306 2 Aramaki Aoba, Sendai 980 8579, Japan
    J Biomech 42:824-9. 2009
    ..These explicit descriptions containing flow-related variables are useful for understanding of the glottal aerodynamics particularly at high frequency range of the falsetto voice register...
  7. doi A versatile micro-mechanical tester for actin stress fibers isolated from cells
    Tsubasa S Matsui
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Sendai, Japan
    Biorheology 46:401-15. 2009
    ..The technique described here is useful for examining the quantitative relationship between mechanical behavior and related structural changes of biomaterials...
  8. ncbi Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells
    Shinji Deguchi
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Sendai 9808579, Japan
    J Biomech 39:2603-10. 2006
    ..These results suggest that SFs can bear intracellular stresses that may affect overall cell mechanical properties and will impact interpretation of intracellular stress distribution and force-transmission mechanism in adherent cells...
  9. ncbi Computer-aided technique for automatic determination of the relationship between transglottal pressure change and voice fundamental frequency
    Shinji Deguchi
    Center for Research Strategy and Support, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan
    Ann Otol Rhinol Laryngol 117:876-80. 2008
    ..Here, we provide a computer-aided technique that enables one to carry out the determination easily and accurately...
  10. doi Actin stress fibers are at a tipping point between conventional shortening and rapid disassembly at physiological levels of MgATP
    Tsubasa S Matsui
    Department of Biomedical Engineering, Tohoku University, Japan
    Biochem Biophys Res Commun 395:301-6. 2010
    ..The present study thus describes a putative mechanism for rapid SF disassembly caused by decreased myosin activity or sudden cell shortening...
  11. pmc Non-muscle myosin II induces disassembly of actin stress fibres independently of myosin light chain dephosphorylation
    Tsubasa S Matsui
    Department of Biomedical Engineering, Tohoku University, Sendai 980 8579, Japan
    Interface Focus 1:754-66. 2011
    ..Thus, the present study suggests that reducing the number of actin-myosin crossbridges promotes rapid and orientation-dependent disassembly of SFs after cell shortening...
  12. ncbi Flow-induced hardening of endothelial nucleus as an intracellular stress-bearing organelle
    Shinji Deguchi
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, Sendai 9808579, Japan
    J Biomech 38:1751-9. 2005
    ..Based of these results and a transmission electron microscopy, a possibility of the nucleus as an intracellular compression-bearing organelle was proposed, which will impact interpretation of stress distribution in adherent cells...
  13. doi Biomechanical properties of actin stress fibers of non-motile cells
    Shinji Deguchi
    Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan Graduate School of Engineering, Tohoku University, Sendai, Japan
    Biorheology 46:93-105. 2009
    ....
  14. doi Aligning cells in arbitrary directions on a membrane sheet using locally formed microwrinkles
    Akira C Saito
    Department of Biomedical Engineering, Tohoku University, Sendai, Japan
    Biotechnol Lett 36:391-6. 2014
    ..This technique potentially enables a versatile design of microwrinkles for target-compatible cell alignments. ..
  15. doi High extensibility of stress fibers revealed by in vitro micromanipulation with fluorescence imaging
    Tsubasa S Matsui
    Department of Biomolecular Sciences, Tohoku University, Japan
    Biochem Biophys Res Commun 434:444-8. 2013
    ....