Kazuhiro Tateda

Summary

Affiliation: Toho University
Country: Japan

Publications

  1. ncbi request reprint Efficacy of beta-lactam antibiotics combined with gentamicin against penicillin-resistant pneumococcal pneumonia in CBA/J mice
    K Tateda
    Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    J Antimicrob Chemother 43:367-71. 1999
  2. ncbi request reprint Semi-quantitative analysis of Streptococcus pneumoniae urinary antigen: kinetics of antigen titers and severity of diseases
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, Ohmori Nishi, Tokyo, Japan
    Scand J Infect Dis 38:166-71. 2006
  3. ncbi request reprint Suppression of Pseudomonas aeruginosa quorum-sensing systems by macrolides: a promising strategy or an oriental mystery?
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo, 143 8540, Japan
    J Infect Chemother 13:357-67. 2007
  4. pmc Legionella pneumophila evades gamma interferon-mediated growth suppression through interleukin-10 induction in bone marrow-derived macrophages
    Sadako Yoshizawa
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Infect Immun 73:2709-17. 2005
  5. ncbi request reprint Regulatory effects of macrolides on bacterial virulence: potential role as quorum-sensing inhibitors
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Curr Pharm Des 10:3055-65. 2004
  6. ncbi request reprint 'Break-point Checkerboard Plate' for screening of appropriate antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ohtaku, Tokyo, Japan
    Scand J Infect Dis 38:268-72. 2006
  7. pmc The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils
    Kazuhiro Tateda
    Department of Microbiology, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Infect Immun 71:5785-93. 2003
  8. ncbi request reprint [Antibiotic-resistant bacteria and new directions of antimicrobial chemotherapy]
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ota ku, Tokyo 143 8540, Japan
    Rinsho Byori 60:443-8. 2012
  9. ncbi request reprint Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia
    K Tateda
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Immunol 166:3355-61. 2001
  10. ncbi request reprint Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response
    K Tateda
    Department of Microbiology, Toho University School of Medicine, 5 21 16 Ohmori nishi, Ohta ku, Tokyo 143 8540, Japan
    J Infect Chemother 6:1-7. 2000

Detail Information

Publications74

  1. ncbi request reprint Efficacy of beta-lactam antibiotics combined with gentamicin against penicillin-resistant pneumococcal pneumonia in CBA/J mice
    K Tateda
    Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    J Antimicrob Chemother 43:367-71. 1999
    ..5 and 10 mg/kg) was used with gentamicin. Our results suggest that gentamicin, when combined with beta-lactam antibiotics, especially imipenem, may be potentially useful against PRSP pneumonia in noncompromised individuals...
  2. ncbi request reprint Semi-quantitative analysis of Streptococcus pneumoniae urinary antigen: kinetics of antigen titers and severity of diseases
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, Ohmori Nishi, Tokyo, Japan
    Scand J Infect Dis 38:166-71. 2006
    ..pneumoniae antigen titer determination in urine and serum, which may be crucial not only for diagnostic measures, but also may provide a better understanding of the pathogenesis of S. pneumoniae infection...
  3. ncbi request reprint Suppression of Pseudomonas aeruginosa quorum-sensing systems by macrolides: a promising strategy or an oriental mystery?
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo, 143 8540, Japan
    J Infect Chemother 13:357-67. 2007
    ..aeruginosa, particularly the potential activity of this antibiotic to suppress the bacterial quorum-sensing system...
  4. pmc Legionella pneumophila evades gamma interferon-mediated growth suppression through interleukin-10 induction in bone marrow-derived macrophages
    Sadako Yoshizawa
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Infect Immun 73:2709-17. 2005
    ..These data provide new insights not only into the cellular mechanisms of Th1-Th2 cross talk in Legionella-infected macrophages but also into the pathogenesis of L. pneumophila pneumonia in humans...
  5. ncbi request reprint Regulatory effects of macrolides on bacterial virulence: potential role as quorum-sensing inhibitors
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Curr Pharm Des 10:3055-65. 2004
    ..aeruginosa, particularly the ability of this antibiotic to suppress quorum-sensing systems, which may be crucial in the pathogenesis of chronic P. aeruginosa infection...
  6. ncbi request reprint 'Break-point Checkerboard Plate' for screening of appropriate antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ohtaku, Tokyo, Japan
    Scand J Infect Dis 38:268-72. 2006
    ..Our data suggest a usefulness of 'Break-point Checkerboard Plate' to screen appropriate antibiotic combinations against drug resistant organisms, including MDRP...
  7. pmc The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils
    Kazuhiro Tateda
    Department of Microbiology, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Infect Immun 71:5785-93. 2003
    ..Our data suggest that the quorum-sensing molecule 3-oxo-C(12)-HSL has critical roles in the pathogenesis of P. aeruginosa infection, not only in the induction of bacterial virulence factors but also in the modulation of host responses...
  8. ncbi request reprint [Antibiotic-resistant bacteria and new directions of antimicrobial chemotherapy]
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ota ku, Tokyo 143 8540, Japan
    Rinsho Byori 60:443-8. 2012
    ..In this article, recent topics regarding antibiotic-resistant organisms are briefly reviewed and the directions of antibiotic chemotherapy against these organisms are discussed...
  9. ncbi request reprint Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia
    K Tateda
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Immunol 166:3355-61. 2001
    ..pneumophila infection, not via direct killing but more immunomodulatory effects. Our results suggest that the early recruitment of neutrophils may contribute to T1 polarization in a murine model of L. pneumophila pneumonia...
  10. ncbi request reprint Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response
    K Tateda
    Department of Microbiology, Toho University School of Medicine, 5 21 16 Ohmori nishi, Ohta ku, Tokyo 143 8540, Japan
    J Infect Chemother 6:1-7. 2000
    ..Moreover, it is likely that the macrolides may sensitize bacteria to stresses, as these antibiotics induced alterations in a major stress protein, Gro-EL, in constitutive and inducible states...
  11. doi request reprint Interleukin-1 deficiency in combination with macrophage depletion increases susceptibility to Pseudomonas aeruginosa bacteremia
    Tetsuya Horino
    Department of Infectious Disease and Infection Control, The Jikei University School of Medicine, 3 19 18 Nishi Shimbashi, Minato ku, Tokyo, Japan
    Microbiol Immunol 53:502-11. 2009
    ..Thus, IL-1 deficiency becomes disadvantageous during P. aeruginosa bacteremia when it is accompanied by immunosuppression, particularly when macrophage functions are seriously impaired...
  12. ncbi request reprint Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model
    Etsu T Fuse
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143 8540, Japan
    J Med Microbiol 56:305-12. 2007
    ..pneumophila pneumonia in mice. The results showed that TLR2-mediated recognition of Legionella LPS and subsequent chemokine-dependent cellular recruitment may be a crucial host innate response in L. pneumophila pneumonia...
  13. doi request reprint Hyperoxia exaggerates bacterial dissemination and lethality in Pseudomonas aeruginosa pneumonia
    Yoshiaki Kikuchi
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo, Japan
    Pulm Pharmacol Ther 22:333-9. 2009
    ..aeruginosa pneumonia. Our data identify the potential of macrolides to protect individuals with P. aeruginosa pneumonia in the setting of hyperoxia...
  14. pmc Molecular characterization of extraintestinal Escherichia coli isolates in Japan: relationship between sequence types and mutation patterns of quinolone resistance-determining regions analyzed by pyrosequencing
    Nozomi Aoike
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
    J Clin Microbiol 51:1692-8. 2013
    ..coli isolates. This high-throughput method for analyzing QRDR mutations by pyrosequencing is a powerful tool for epidemiological studies of fluoroquinolone resistance in bacteria...
  15. doi request reprint Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa
    Nobumasa Aoki
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
    J Antimicrob Chemother 63:534-42. 2009
    ..Recent data demonstrate that colistin may be effective for these patients, although limited in vitro and in vivo data are available. Our aim was to identify further characteristics of colistin for the therapy of pneumonia caused by MDRP...
  16. doi request reprint Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species
    Soichiro Kimura
    Department of Microbiology and Infectious Diseases, Toho University Faculty of Medicine, Ota ku, Tokyo 143 8540, Japan
    Microbiology 155:1934-9. 2009
    ..pneumophila exposed to 3-oxo-C(12)-HSL. Our results suggest that the Pseudomonas QS autoinducer 3-oxo-C(12)-HSL exerts both bacteriostatic and virulence factor-suppressive activities on L. pneumophila alone...
  17. ncbi request reprint Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate
    Takao Kobayashi
    Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    J Antimicrob Chemother 50:59-66. 2002
    ..Accumulating data have demonstrated that macrolide antibiotics suppress Pseudomonas aeruginosa virulence, which may explain the efficacy of macrolides in clinical settings. We examined the virulence of macrolide-treated bacteria in vivo...
  18. ncbi request reprint Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches
    Natsue Hosono Honda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143 8530, Japan
    Microbes Environ 26:160-4. 2011
    ..Tetramic acid and disinfectants acted synergistically to kill P. aeruginosa. These results suggest the AHL-degradation product tetramic acid to be useful for bacterial control...
  19. ncbi request reprint Legionella-induced acute lung injury in the setting of hyperoxia: protective role of tumour necrosis factor-alpha
    Chiharu Nara
    Department of Microbiology, Toho University School of Medicine, Tokyo 143 8540, Japan
    J Med Microbiol 53:727-33. 2004
    ..pneumophila pneumonia. The data suggest that TNF-alpha may be a potential therapeutic candidate for these individuals, not only through modulating host antibacterial systems, but also by mediating induction of the antioxidant GSH...
  20. pmc In vitro antibacterial activity of modithromycin, a novel 6,11-bridged bicyclolide, against respiratory pathogens, including macrolide-resistant Gram-positive cocci
    Takafumi Sato
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ota ku, Tokyo 143 8540, Japan
    Antimicrob Agents Chemother 55:1588-93. 2011
    ....
  21. pmc Virulence-suppressing effects of linezolid on methicillin-resistant Staphylococcus aureus: possible contribution to early defervescence
    Sadako Yoshizawa
    Department of Infection Control, Toho University Omori Medical Center, Tokyo, Japan
    Antimicrob Agents Chemother 56:1744-8. 2012
    ..These data may explain at least in part early defervescence observed in LZD-treated individuals...
  22. doi request reprint Molecular characterization of carbapenem-non-susceptible Acinetobacter spp. in Japan: predominance of multidrug-resistant Acinetobacter baumannii clonal complex 92 and IMP-type metallo-β-lactamase-producing non-baumannii Acinetobacter species
    Yuichi Kouyama
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Omori Nishi, Ota ku, Tokyo, 1438540, Japan
    J Infect Chemother 18:522-8. 2012
    ..This is the first report describing the nationwide molecular epidemiology of carbapenem-non-susceptible Acinetobacter spp. with genomic species-level identification in Japan...
  23. ncbi request reprint Interleukin-1-deficient mice exhibit high sensitivity to gut-derived sepsis caused by Pseudomonas aeruginosa
    Tetsuya Horino
    Department of Internal Medicine, Jikei University School of Medicine, Nishi Shimbashi, Minato ku, Tokyo, Japan
    Cytokine 30:339-46. 2005
    ..We evaluated the role of endogenous IL-1 in gut-derived sepsis caused by Pseudomonas aeruginosa, by comparing IL-1-deficient mice and wild-type (WT) mice...
  24. doi request reprint Sequential changes of Legionella antigens and bacterial load in the lungs and urines of a mouse model of pneumonia
    Yu Chen
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143 8540, Japan
    Diagn Microbiol Infect Dis 66:253-60. 2010
    ..The present data suggested prolonged and compartmentalized deposition of antigen in the lungs, which may have an impact on the diagnosis of L. pneumophila pneumonia, especially in missed cases even after recovery from disease...
  25. ncbi request reprint Efficacies of calcium-EDTA in combination with imipenem in a murine model of sepsis caused by Escherichia coli with NDM-1 β-lactamase
    Ayumi Yoshizumi
    Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University School of Medicine, Tokyo, 143 8540, Japan
    J Infect Chemother 19:992-5. 2013
    ..These data demonstrated the possibility of Ca-EDTA for clinical applications. In our understanding, this is the first report examining the effect of Ca-EDTA on a mouse sepsis model caused by NDM-1-producing bacteria. ..
  26. doi request reprint Protective effect of procysteine on Acinetobacter pneumonia in hyperoxic conditions
    Keisuke Saito
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143 8540, Japan
    J Antimicrob Chemother 68:2305-10. 2013
    ..In this study, we examined the effect of the antioxidant procysteine on Acinetobacter murine pneumonia in hyperoxic conditions in order to simulate VAP...
  27. doi request reprint A peptide based on homologous sequences of the β-barrel assembly machinery component BamD potentiates antibiotic susceptibility of Pseudomonas aeruginosa
    Nobuaki Mori
    Department of Microbiology and Infectious Diseases, Toho University Faculty of Medicine, Tokyo, Japan
    J Antimicrob Chemother 67:2173-81. 2012
    ..This study aimed to identify effects of a synthetic peptide based on conserved sequences in the putative BamA-binding region of BamD, focusing on antibiotic susceptibility and OMP characteristics in P. aeruginosa...
  28. ncbi request reprint [Quorum-sensing system of Pseudomonas aeruginosa--a novel target for antibacterial agents]
    Kazuhiro Tateda
    Department of Microbiology and Infectious Disease, Toho University School of Medicine
    Nihon Saikingaku Zasshi 59:543-9. 2004
  29. ncbi request reprint [Analysis of period of positive urinary antigen detection kit for Streptococcus pneumoniae in patients with pneumococcal pneumonia]
    Kanako Yoshida
    Second Department of Internal Medicine, Toho University School of Medicine, 6 11 1 Omori Nishi, Ota ku, Tokyo, 143 8541, Japan
    Nihon Kokyuki Gakkai Zasshi 41:521-5. 2003
    ..However, because the positive test kit results are prolonged after recovery from pneumonia in some cases, this kit is not suitable for the evaluation of therapeutic effect...
  30. pmc Efficacy of calcium-EDTA as an inhibitor for metallo-β-lactamase in a mouse model of Pseudomonas aeruginosa pneumonia
    Nobumasa Aoki
    Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 143 8540, Japan
    Antimicrob Agents Chemother 54:4582-8. 2010
    ..These data suggest the therapeutic potential of Ca-EDTA not only by the blocking of MBLs but also by neutralizing tissue-damaging metalloproteases in P. aeruginosa infections...
  31. pmc In vitro intracellular activity and in vivo efficacy of modithromycin, a novel bicyclolide, against Legionella pneumophila
    Takafumi Sato
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Ota ku, Tokyo 143 8540, Japan
    Antimicrob Agents Chemother 55:1594-7. 2011
    ..pneumophila. Modithromycin should be a useful agent for treatment of pulmonary infections caused by this pathogen...
  32. ncbi request reprint Predictive analysis of ceftazidime hydrolysis in CTX-M-type beta-lactamase family members with a mutational substitution at position 167
    Soichiro Kimura
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 1438540, Japan
    Int J Antimicrob Agents 29:326-31. 2007
    ..73-2.21 times higher than those of their respective wild-type enzymes. These results indicate that the CTX-M-type beta-lactamase family can hydrolyse ceftazidime more efficiently because of the point mutation at position 167...
  33. doi request reprint Genotyping of skin and soft tissue infection (SSTI)-associated methicillin-resistant Staphylococcus aureus (MRSA) strains among outpatients in a teaching hospital in Japan: application of a phage-open reading frame typing (POT) kit
    Tadashi Maeda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 143 8540, Japan
    J Infect Chemother 18:906-14. 2012
    ..These data also underscore the utility of the POT-kit for non-outbreak surveillance through its simple platform consisting of two multiplex PCRs without sequencing...
  34. pmc Efficacy of bacteriophage therapy against gut-derived sepsis caused by Pseudomonas aeruginosa in mice
    Ryohei Watanabe
    Third Department of Surgery, Toho University School of Medicine, Tokyo, Japan
    Antimicrob Agents Chemother 51:446-52. 2007
    ..In conclusion, our findings suggest that oral administration of phage may be effective against gut-derived sepsis caused by P. aeruginosa...
  35. pmc Roles of interleukin-17 in an experimental Legionella pneumophila pneumonia model
    Yoshifumi Kimizuka
    Department of Microbiology and Infectious Disease, Toho University School of Medicine, Tokyo, Japan
    Infect Immun 80:1121-7. 2012
    ..These results demonstrate that IL-17A/F plays a critical role in L. pneumophila pneumonia, probably through induction of proinflammatory cytokines and accumulation of neutrophils at the infection site...
  36. ncbi request reprint Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study
    Sadatomo Tasaka
    Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo
    Intern Med 49:273-81. 2010
    ..Although PCP in patients with acquired immunodeficiency syndrome (AIDS) has been extensively described, its characteristics in non-AIDS patients, such as those with malignancies, are not thoroughly documented...
  37. ncbi request reprint Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae
    Masaaki Tanabe
    Department of Microbiology, Omori Hospital, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku Tokyo, Japan
    J Med Microbiol 54:7-13. 2005
    ..The data suggest that compensatory production of TNF-alpha in IL-1 KO mice contributes to the host defence against K. pneumoniae infection...
  38. ncbi request reprint Use of culture-independent analysis to reveal alteration of intestinal microflora by heat-killed Lactobacillus pentosus in a mouse model of endogenous sepsis
    Yasuyuki Sugasawa
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo, 143 8540, Japan
    J Infect Chemother 19:673-6. 2013
    ....
  39. doi request reprint Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis
    Masato Tashiro
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
    Med Mycol 50:353-60. 2012
    ..albicans infections. Synergistic antifungal activity and suppression of HMG-CoA reductase-associated Candida virulence factors, including farnesol, may explain, at least in part, the in vivo efficacy of pravastatin...
  40. pmc Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate
    Sohei Harada
    Department of Microbiology and Infectious Diseases, School of Medicine, Faculty of Medicine, Toho University, Omori Nishi, Ota ku, 143 8540 Tokyo, Japan
    Antimicrob Agents Chemother 54:3545-50. 2010
    ....
  41. ncbi request reprint High frequency of erythromycin A resistance and distribution of mefE and ermB genes in clinical isolates of Streptococcus pneumoniae in Japan
    Hiroki Okamoto
    Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    J Infect Chemother 8:28-32. 2002
    ..pneumoniae in Japan. In addition, it is likely that ermB-positive isolates with low-level resistance show heterogeneous high-level resistance...
  42. ncbi request reprint [In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007]
    Keizo Yamaguchi
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine
    Jpn J Antibiot 62:346-70. 2009
    ..coli, P. aeruginosa, and N. gonorrhoeae showed resistance tendencies, and other species maintained high susceptibility rates more than 90% against FQs, which have been used clinically for over 15 years...
  43. ncbi request reprint Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection
    Wan C Tsai
    Department of Pediatrics, Division of Pediatric Pulmonary Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109 0642, USA
    Am J Respir Crit Care Med 170:1331-9. 2004
    ....
  44. doi request reprint Evidence of intravenous immunoglobulin as a critical supportive therapy against Clostridium difficile toxin-mediated lethality in mice
    Tomoaki Saito
    Department of Microbiology and Infectious Diseases, Toho University Faculty of Medicine, Tokyo, Japan
    J Antimicrob Chemother 66:1096-9. 2011
    ..difficile infections, but the clinical evidence is still limited. We examined the efficacy of intravenous immunoglobulin (IVIg) in C. difficile toxin (CDT)-mediated lethality and cellular injury in mice...
  45. ncbi request reprint [Evaluation of Streptococcus pneumoniae-urinary antigen detection kit in patients with community acquired pneumonia]
    Takao Kobayashi
    Department of Microbiology, Toho University School of Medicine
    Kansenshogaku Zasshi 76:995-1002. 2002
    ..Since it is not technically complex, does not require equipment, and detects within as quickly as in 15 minutes, the S. pneumoniae urinary antigen kit is useful for rapid diagnosis of community acquired pneumonia in adults...
  46. pmc Chromosomal integration and location on IncT plasmids of the blaCTX-M-2 gene in Proteus mirabilis clinical isolates
    Sohei Harada
    Department of Microbiology and Infectious Diseases, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan
    Antimicrob Agents Chemother 56:1093-6. 2012
    ..In all four isolates with chromosomal bla(CTX-M-2), ISEcp1 was responsible for the integration of the gene into the chromosome. Three different sites in the P. mirabilis genomic sequence were utilized as integration sites...
  47. pmc Anti-Clostridium difficile potential of tetramic acid derivatives from Pseudomonas aeruginosa quorum-sensing autoinducers
    Chihiro Ueda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Ohmorinishi, Ohtaku, Tokyo 143 8540, Japan
    Antimicrob Agents Chemother 54:683-8. 2010
    ..These results suggest the potential for tetramic acid derivatives to be novel agents with activity against C. difficile...
  48. ncbi request reprint Hyperoxia mediates acute lung injury and increased lethality in murine Legionella pneumonia: the role of apoptosis
    Kazuhiro Tateda
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Immunol 170:4209-16. 2003
    ..pneumophila pneumonia. Exaggerated apoptosis, in part through Fas-mediated signaling, may accelerate hyperoxia-induced acute lung injury in Legionella pneumonia...
  49. doi request reprint Paradoxically high resistance of natural killer T (NKT) cell-deficient mice to Legionella pneumophila: another aspect of NKT cells for modulation of host responses
    Kayoko Hayakawa
    Department of Microbiology and Infectious Diseases, Toho University, School of Medicine, Tokyo, Japan
    J Med Microbiol 57:1340-8. 2008
    ..The regulation of IL-1beta, IL-18 and caspase-1 may be associated with the modulating effect of host responses by NKT cells...
  50. ncbi request reprint Sepsis caused by food-borne infection with Escherichia coli
    Keiko Wachi
    Respiratory Disease Center, Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    Intern Med 44:1316-9. 2005
    ..Serotype O-143 is recognized in enteroinvasive E. coli (EIEC) as well as in Shigella dysenteriae. The pathogen in the present case is suspected of being EIEC although the isolated E. coli strain was negative for the inv and ipa genes...
  51. ncbi request reprint Evaluation of antimicrobial susceptibility for beta-lactams using the Etest method against clinical isolates from 100 medical centers in Japan (2006)
    Yoshikazu Ishii
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Faculty of Medicine, Tokyo 1438540, Japan
    Diagn Microbiol Infect Dis 60:177-83. 2008
    ....
  52. ncbi request reprint [Quorum-sensing systems in bacteria]
    Kazuhiro Tateda
    Department of Microbiology, Toho University School of Medicine
    Nihon Rinsho 61:272-9. 2003
  53. pmc Characterization of qnrB-like genes in Citrobacter species of the American Type Culture Collection
    Tomoo Saga
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Oota ku, Tokyo, Japan
    Antimicrob Agents Chemother 57:2863-6. 2013
    ..freundii ATCC 8090(T) and ATCC 43864. No qnrB-like sequence was found in Citrobacter koseri ATCC 27028(T). These findings underscore the close relationship between this species and qnrB...
  54. ncbi request reprint Evaluation of Camellia sinensis catechins as a swine antimicrobial feed additive that does not cause antibiotic resistance
    Akira Ohno
    Department of Microbiology and Infectious Diseases, Toho University, Japan
    Microbes Environ 28:81-6. 2013
    ..Thus, it can be concluded that green tea leaves are a safe feed additive alternative to AGPs...
  55. doi request reprint Nationwide surveillance of bacterial respiratory pathogens conducted by the Surveillance Committee of Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Clinical Microbiology in 2009: general view of t
    Akira Watanabe
    The Surveillance Committee of Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology, c o Japanese Society of Chemotherapy, Nichinai Kaikan B1, 3 28 8 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    J Infect Chemother 18:609-20. 2012
    ..Continuous national surveillance of the antimicrobial susceptibility of respiratory pathogens is crucial to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis...
  56. doi request reprint Evaluation of antimicrobial susceptibility for β-lactams against clinical isolates from 51 medical centers in Japan (2008)
    Yoshikazu Ishii
    Faculty of Medicine, Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 1438540, Japan
    Diagn Microbiol Infect Dis 69:443-8. 2011
    ..3%), and imipenem (23.5%). The proportion of strains resistant to β-lactam antimicrobials has decreased compared with data from 2006 (Diagn. Microbiol. Infect. Dis. 60:177-183), reflecting the reduced consumption of β-lactams in Japan...
  57. pmc Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
    Ari B Molofsky
    Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Exp Med 203:1093-104. 2006
    ..Accordingly, macrophages respond to cytosolic flagellin by a mechanism that requires Naip5 and caspase 1 to restrict bacterial replication and release proinflammatory cytokines that control L. pneumophila infection...
  58. ncbi request reprint The in vitro and in vivo antibacterial characterization of vancomycin and linezolid against vancomycin-susceptible and -resistant enterococci
    Shuichi Miyazaki
    Department of Microbiology, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 143, Japan
    J Antimicrob Chemother 50:971-4. 2002
    ..faecalis because this drug had potent in vitro activity against the organisms. Our results indicate that linezolid is suitable for the treatment of VRE and VSEF bacteraemia, and vancomycin is suitable for VSEF bacteraemia...
  59. ncbi request reprint Identification of biochemically atypical Staphylococcus aureus clinical isolates with three automated identification systems
    Yoshikazu Ishii
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 1438540, Japan
    J Med Microbiol 55:387-92. 2006
    ..This study shows that it is possible to identify these physiologically atypical S. aureus isolates correctly by using the Phoenix and AutoScan-4 fully automatic identification systems...
  60. ncbi request reprint [Streptococcus pneumoniae infection]
    Kazuhiro Tateda
    Department of Microbiology, Toho University School of Medicine
    Nihon Rinsho 61:323-9. 2003
  61. ncbi request reprint A case of NDM-1-producing Acinetobacter baumannii transferred from India to Japan
    Yasushi Nakazawa
    Department of Infection Control and Infectious Disease, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minatoku ku, Tokyo, Japan
    J Infect Chemother 19:330-2. 2013
    ..Our case suggests that NDM-1-producing bacteria could be introduced into our country easily. There is concern that various resistant bacteria may be transferred from epidemic countries as a result of international medical care...
  62. pmc Diagnostic usefulness of ribosomal protein l7/l12 for pneumococcal pneumonia in a mouse model
    Tomoka Sawa
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
    J Clin Microbiol 51:70-6. 2013
    ..Bacterial RP-L7/L12 may be a promising target for the development of new methods to diagnose infectious disease. Further studies are warranted to determine whether such a test could be useful in children...
  63. ncbi request reprint [Isolation rate and susceptibilities of Candida species from blood, vascular catheter, urine and stool]
    Masato Tashiro
    Department of Microbiology, Toho University School of Medicine
    Kansenshogaku Zasshi 84:187-92. 2010
    ..Both C. albicans and non-Candida spp. isolated from urine increased slightly over the past 7 years. Flucytosine, fluconazole, itraconazole and micafungin still have strong activity against Candida isolates...
  64. pmc In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates
    Yoshikazu Ishii
    Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University School of Medicine, 5 21 16 Omori nishi, Ota ku, Tokyo 143 8540, Japan
    Antimicrob Agents Chemother 54:3625-9. 2010
    ..Results of this study indicate that ME1071 can potentiate the activity of ceftazidime and carbapenems against MBL-producing strains of P. aeruginosa...
  65. ncbi request reprint In vitro antibacterial activities of new fluoroquinolones against clinical isolates of haemophilus influenzae with ciprofloxacin-resistance-associated alterations in GyrA and ParC
    Satoshi Yoshizumi
    Department of Microbiology, Toho University School of Medicine, Tokyo, Japan
    Chemotherapy 50:265-75. 2004
    ..The in vitro antimicrobial activities of new fluoroquinolones were tested against quinolone-resistant Haemophilus influenzae of clinical isolates...
  66. pmc Familial spread of a virulent clone of Klebsiella pneumoniae causing primary liver abscess
    Sohei Harada
    Department of Microbiology and Infectious Diseases, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan
    J Clin Microbiol 49:2354-6. 2011
    ..The causative isolates had identical pulsed-field gel electrophoresis patterns and were determined to be sequence type 23. An additional member of the family was found to carry the same strain without clinical manifestation...
  67. ncbi request reprint [Antibiotic-resistant Streptococcus pneumoniae]
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine
    Nihon Rinsho 65:410-3. 2007
  68. ncbi request reprint A case of Legionella pneumophila pneumonia complicated by miliary tuberculosis
    Kou Uchida
    Second Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
    Respirology 8:249-51. 2003
    ..A diagnosis of miliary tuberculosis was confirmed. The present case should alert physicians to this potentially confusing combination of respiratory pathogens...
  69. ncbi request reprint Prevalence of Chlamydophila pneumoniae among Bangladeshi children under age 5 years with acute respiratory infections
    Tetsuya Matsumoto
    Department of Microbiology, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo, 160 8402, Japan
    J Infect Chemother 12:139-44. 2006
    ..pneumoniae kit) indicated that 13 children (20.3%) were infected with C. pneumoniae. Our results indicate a high prevalence rate of C. pneumoniae, suggesting it is as an important causative pathogen of childhood pneumonia in Bangladesh...
  70. ncbi request reprint [A case of falciparum malaria successfully treated with intravenous artesunate]
    Sadako Yoshizawa
    Department of Microbiology, Toho University School of Medicine
    Kansenshogaku Zasshi 76:888-92. 2002
    ..In Japan, very few cases treated with intravenous Artesunate were reported and our results showed its safe and excellent effect for a Japanese malaria patient...
  71. ncbi request reprint Evaluation of a rapid antigen detection test for Neisseria gonorrhoeae in urine sediment for diagnosis of gonococcal urethritis in males
    Kuri Suzuki
    Department of Urology, Sakura Hospital, Toho University School of Medicine, Sakura, Japan
    J Infect Chemother 10:208-11. 2004
    ..Considering the rapidity and ease of this method, our results suggest that the NOW method might be a useful and reliable diagnostic screening tool for gonococcal urethritis...
  72. ncbi request reprint [Macrolides and ketolides]
    Kazuhiro Tateda
    Department of Microbiology and Infectious Diseases, Toho University School of Medicine
    Nihon Rinsho 65:343-7. 2007
  73. pmc Multicenter study to evaluate bloodstream infection by Helicobacter cinaedi in Japan
    Tetsuya Matsumoto
    Department of Microbiology, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo 160 8402, Japan
    J Clin Microbiol 45:2853-7. 2007
    ..Therefore, our results suggest that bacteremia with H. cinaedi is rare but can occur in compromised hosts other than those with HIV infection in Japan...
  74. ncbi request reprint Computed tomographic features of Legionella pneumophila pneumonia in 38 cases
    Fumikazu Sakai
    Department of Diagnostic Radiology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    J Comput Assist Tomogr 31:125-31. 2007
    ..To characterize the imaging features of Legionella pneumophila pneumonia (LPP)...