K Yasutomo

Summary

Affiliation: The University of Tokushima
Country: Japan

Publications

  1. ncbi request reprint Mutation of DNASE1 in people with systemic lupus erythematosus
    K Yasutomo
    Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Nat Genet 28:313-4. 2001
  2. ncbi request reprint Fas system-mediated apoptosis suppresses lymphopoiesis
    K Yasutomo
    Department of Pediatrics, Univerity of Tokushima, Japan
    J Immunol 157:1981-6. 1996
  3. ncbi request reprint The Fas-deficient SCID mouse exhibits the development of T cells in the thymus
    K Yasutomo
    Department of Pediatrics, University of Tokushima School of Medicine, Tokushima City, Japan
    J Immunol 158:4729-33. 1997
  4. ncbi request reprint Pathological lymphocyte activation by defective clearance of self-ligands in systemic lupus erythematosus
    K Yasutomo
    Department of Immunology and Parasitology, School of Medicine, The University of Tokushima, 3 18 15 Kuramoto, Japan
    Rheumatology (Oxford) 42:214-22. 2003
  5. ncbi request reprint A monoclonal antibody (1F3) to human glomerular epithelial cells: a new marker for renal epithelial cell injury
    S Kagami
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    Nephron 75:65-71. 1997
  6. ncbi request reprint Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB
    S Kagami
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    J Am Soc Nephrol 10:779-89. 1999
  7. ncbi request reprint Defective T cells from gld mice play a pivotal role in development of Thy-1.2+B220+ cells and autoimmunity
    K Yasutomo
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    J Immunol 153:5855-64. 1994
  8. ncbi request reprint TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type
    K Yasutomo
    Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 165:3015-22. 2000

Detail Information

Publications8

  1. ncbi request reprint Mutation of DNASE1 in people with systemic lupus erythematosus
    K Yasutomo
    Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Nat Genet 28:313-4. 2001
    ..These data are consistent with the hypothesis that a direct connection exists between low activity of DNASE1 and progression of human SLE...
  2. ncbi request reprint Fas system-mediated apoptosis suppresses lymphopoiesis
    K Yasutomo
    Department of Pediatrics, Univerity of Tokushima, Japan
    J Immunol 157:1981-6. 1996
    ..Furthermore, the Fas ligand overexpression sufficient to impair lymphopoiesis appears to require MHC-restricted T cell activation. These results suggest that the Fas system suppresses lymphopoiesis in vivo...
  3. ncbi request reprint The Fas-deficient SCID mouse exhibits the development of T cells in the thymus
    K Yasutomo
    Department of Pediatrics, University of Tokushima School of Medicine, Tokushima City, Japan
    J Immunol 158:4729-33. 1997
    ..These results suggest that the Fas system plays an essential role in regulating the development of intrathymic T cells as well as peripheral T cells...
  4. ncbi request reprint Pathological lymphocyte activation by defective clearance of self-ligands in systemic lupus erythematosus
    K Yasutomo
    Department of Immunology and Parasitology, School of Medicine, The University of Tokushima, 3 18 15 Kuramoto, Japan
    Rheumatology (Oxford) 42:214-22. 2003
    ..Thus, here we review current findings about the association of the defective clearance of autoantigens and SLE, focusing on mutations in the DNase I locus and their relationship to SLE...
  5. ncbi request reprint A monoclonal antibody (1F3) to human glomerular epithelial cells: a new marker for renal epithelial cell injury
    S Kagami
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    Nephron 75:65-71. 1997
    ..These results indicate that Mab, 1F3 marks phenotypic changes of renal epithelial cells under disease conditions and may be a useful marker for progressive kidney diseases...
  6. ncbi request reprint Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB
    S Kagami
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    J Am Soc Nephrol 10:779-89. 1999
    ..Alpha1 integrin-mediated mesangial matrix remodeling induced by TGF-beta or PDGF-BB may be a pathogenic mechanism leading to glomerular scarring...
  7. ncbi request reprint Defective T cells from gld mice play a pivotal role in development of Thy-1.2+B220+ cells and autoimmunity
    K Yasutomo
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    J Immunol 153:5855-64. 1994
    ..g., lymphoproliferation, immune-based nephritic disease, and autoantibody production. These findings also suggest that the Fas ligand is selectively expressed on T cells...
  8. ncbi request reprint TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type
    K Yasutomo
    Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 165:3015-22. 2000
    ....