Toshiyuki Yasui

Summary

Affiliation: The University of Tokushima
Country: Japan

Publications

  1. ncbi request reprint Factors associated with premature ovarian failure, early menopause and earlier onset of menopause in Japanese women
    Toshiyuki Yasui
    Department of Reproductive Technology, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto Cho, Tokushima, Japan
    Maturitas 72:249-55. 2012
  2. doi request reprint Association of endometriosis-related infertility with age at menopause
    Toshiyuki Yasui
    Department of Reproductive Technology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Maturitas 69:279-83. 2011
  3. ncbi request reprint Associations of endogenous sex hormones and sex hormone-binding globulin with lipid profiles in aged Japanese men and women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Clin Chim Acta 398:43-7. 2008
  4. doi request reprint Changes in insulin sensitivity during GnRH agonist treatment in premenopausal women with leiomyoma
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Clin Chim Acta 413:960-5. 2012
  5. doi request reprint Interleukin-7 is associated with monocyte chemoattractant protein-1 and soluble E-selectin levels in peripheral blood of newly post-menopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    J Reprod Immunol 81:97-102. 2009
  6. ncbi request reprint Change in serum undercarboxylated osteocalcin concentration in bilaterally oophorectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Maturitas 56:288-96. 2007
  7. ncbi request reprint Undercarboxylated osteocalcin concentration in postmenopausal women receiving hormone therapy daily and on alternate days
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 13:314-22. 2006
  8. doi request reprint Differences in bone metabolism between singleton pregnancy and twin pregnancy
    Soichiro Nakayama
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Bone 49:513-9. 2011
  9. doi request reprint Effect of immune stress on body weight regulation is altered by ovariectomy in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    J Reprod Immunol 91:41-7. 2011
  10. doi request reprint Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Atherosclerosis 204:471-5. 2009

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Factors associated with premature ovarian failure, early menopause and earlier onset of menopause in Japanese women
    Toshiyuki Yasui
    Department of Reproductive Technology, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto Cho, Tokushima, Japan
    Maturitas 72:249-55. 2012
    ....
  2. doi request reprint Association of endometriosis-related infertility with age at menopause
    Toshiyuki Yasui
    Department of Reproductive Technology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Maturitas 69:279-83. 2011
    ..The purpose of this study was to clarify the association of reproductive factors, including past history of infertility, with menopause in Japanese women...
  3. ncbi request reprint Associations of endogenous sex hormones and sex hormone-binding globulin with lipid profiles in aged Japanese men and women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Clin Chim Acta 398:43-7. 2008
    ..We determined the associations of serum estradiol level and free estradiol index (FEI) with lipid profiles and insulin resistance in aged Japanese men and women...
  4. doi request reprint Changes in insulin sensitivity during GnRH agonist treatment in premenopausal women with leiomyoma
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Clin Chim Acta 413:960-5. 2012
    ....
  5. doi request reprint Interleukin-7 is associated with monocyte chemoattractant protein-1 and soluble E-selectin levels in peripheral blood of newly post-menopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    J Reprod Immunol 81:97-102. 2009
    ..We conclude that there is a relationship between circulating IL-7, MCP-1 and soluble E-selectin, and that IL-7 may be involved in regulating inflammatory cell adhesion together with MCP-1 and E-selectin in post-menopausal women...
  6. ncbi request reprint Change in serum undercarboxylated osteocalcin concentration in bilaterally oophorectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Maturitas 56:288-96. 2007
    ..We investigated changes in serum undercarboxylated osteocalcin (ucOC) concentrations, bone turnover markers and spine bone mineral density (BMD) in women who had undergone bilateral oophorectomy during the premenopausal period...
  7. ncbi request reprint Undercarboxylated osteocalcin concentration in postmenopausal women receiving hormone therapy daily and on alternate days
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 13:314-22. 2006
    ....
  8. doi request reprint Differences in bone metabolism between singleton pregnancy and twin pregnancy
    Soichiro Nakayama
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Bone 49:513-9. 2011
    ....
  9. doi request reprint Effect of immune stress on body weight regulation is altered by ovariectomy in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    J Reprod Immunol 91:41-7. 2011
    ..It is possible that these alterations are caused by OVX-induced obesity rather than the direct effects of gonadal steroid deficiency...
  10. doi request reprint Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Atherosclerosis 204:471-5. 2009
    ..The aim of the present study was to determine the effects of raloxifene on changes in circulating levels of cytokines and chemokines in relation to changes in lipid profiles and markers of inflammation in postmenopausal women...
  11. ncbi request reprint Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact adult female rats
    Toshiya Matsuzaki
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Endocr J 58:1003-12. 2011
    ..Thus, lower kiss1 mRNA levels in the ARC appear to be responsible for the fasting-induced inhibition of gonadotrophin secretion and subsequent prolongation of the estrous cycle...
  12. doi request reprint Neonatal LPS injection alters the body weight regulation systems of rats under non-stress and immune stress conditions
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 28:119-24. 2010
    ..Changes in the endocrine, neuropeptide, and cytokine regulation systems might be involved in these alterations...
  13. ncbi request reprint Changes in central and peripheral inflammatory responses to lipopolysaccharide in ovariectomized female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan Electronic address
    Cytokine 65:65-73. 2014
    ..As supplementation of E and P could not attenuate the anorectic and cytokine responses to LPS, the deficiency of gonadal steroids might not be directly involved in the increase of inflammatory responses in OVX. ..
  14. doi request reprint Different circulating levels of monocyte chemoattractant protein-1 and interleukin-8 during the menopausal transition
    Anna Tani
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto cho 3 18 15, Tokushima 770 8503, Japan
    Cytokine 62:86-90. 2013
    ..The aim of the present study was to clarify the changes in circulating cytokines and chemokines in women during the menopausal transition by using a detailed classification...
  15. doi request reprint Associations of circulating adiponectin with estradiol and monocyte chemotactic protein-1 in postmenopausal women
    Yuka Miyatani
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Menopause 15:536-41. 2008
    ..In addition, the associations of serum adiponectin with serum concentrations of proinflammatory and anti-inflammatory cytokines were examined in women during the menopausal transition...
  16. ncbi request reprint Effects of postmenopausal hormone therapy every day and every other day on lipid levels according to difference in body mass index
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 12:223-31. 2005
    ....
  17. ncbi request reprint Different effects of oral conjugated equine estrogens and transdermal estrogen on undercarboxylated osteocalcin concentration in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 13:651-9. 2006
    ..We also examined the associations of ucOC concentration with estradiol concentration and TG...
  18. doi request reprint Effects of Japanese traditional medicines on circulating cytokine levels in women with hot flashes
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Menopause 18:85-92. 2011
    ..The effects of the Japanese traditional medicines keishibukuryogan and kamishoyosan on circulating cytokines were examined to clarify the difference in the actions of Japanese traditional medicines in women with hot flashes...
  19. doi request reprint Association of circulating adiponectin with testosterone in women during the menopausal transition
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima, Japan
    Maturitas 73:255-60. 2012
    ....
  20. doi request reprint Effects of lipopolysaccharide exposure at different postnatal time points on the response of LH to homotypic stress in adulthood
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    J Reprod Immunol 94:155-60. 2012
    ....
  21. ncbi request reprint Changes in circulating cytokine levels in midlife women with psychological symptoms with selective serotonin reuptake inhibitor and Japanese traditional medicine
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Maturitas 62:146-52. 2009
    ....
  22. ncbi request reprint Changes in serum cytokine concentrations during the menopausal transition
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, University of Tokushima, Kuramoto cho 3 18 15, Tokushima 770 8503, Japan
    Maturitas 56:396-403. 2007
    ....
  23. ncbi request reprint Association of N-terminal pro B-type natriuretic peptide and sex hormone-binding globulin in non-obese peri- and postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Clin Chim Acta 411:280-4. 2010
    ..We also examined the change in circulating NT-proBNP caused by a gonadotrophin-releasing hormone (GnRH) agonist in order to clarify the effect of acute hormone deficiency on NT-proBNP...
  24. doi request reprint Changes in responsiveness of appetite, leptin and hypothalamic IL-1β and TNF-α to lipopolysaccharide in developing rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Neuroimmunol 236:10-6. 2011
    ..In addition, hypothalamic IL-1β mRNA levels were not affected by leptin administration. In conclusion, the absence of a leptin response may act to prevent immune stress-induced anorexia during the early neonatal period...
  25. ncbi request reprint Neuropeptide Y mediates orexin A-mediated suppression of pulsatile gonadotropin-releasing hormone secretion in ovariectomized rats
    Machiko Kiyokawa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    J Med Invest 58:11-8. 2011
    ..To investigate whether neuropeptide Y (NPY) is involved in the orexin A-mediated suppression of pulsatile LH secretion, we evaluated the effects of NPY antibody on the suppressive effect of orexin A...
  26. ncbi request reprint Developmental changes in the responsiveness of hypothalamic ER alpha mRNA levels to food deprivation
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Neuro Endocrinol Lett 34:543-8. 2013
    ..In undernourished rodents, hypothalamic ER alpha mRNA expression are decreased. Responses of some hypothalamic factors to negative energy balance develop during the early neonatal period...
  27. ncbi request reprint Differences in sensitivity to cold in Japanese men and postmenopausal women aged > or =50 years
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Gend Med 4:359-66. 2007
    ..However, no previous studies have examined the differences in sensitivity to cold in men and women or the association of hormonal levels with sensitivity to cold...
  28. doi request reprint Prepubertal exposure to glucocorticoid delays puberty independent of the hypothalamic Kiss1-GnRH system in female rats
    Riyo Kinouchi
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Int J Dev Neurosci 30:596-601. 2012
    ..These results suggest that the delayed onset of puberty induced by prepubertal dexamethasone administration occurs independent of the hypothalamic Kiss1-GnRH system...
  29. doi request reprint Effects of oral and transdermal estrogen therapies on circulating cytokines and chemokines in postmenopausal women with hysterectomy
    Toshiyuki Yasui
    Department of Obstetrics, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima, Japan
    Eur J Endocrinol 161:267-73. 2009
    ....
  30. ncbi request reprint Circulating osteoprotegerin is associated with age and systolic blood pressure, but not with lipid profile or fasting glucose, in postmenopausal women
    Hirokazu Uemura
    Department of Preventive Medicine, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Menopause 15:180-4. 2008
    ..The aim of this study was to clarify the relationships between circulating OPG and the risk factors for vascular disorders in postmenopausal women...
  31. doi request reprint Estradiol suppresses NMU mRNA expression during sexual maturation in the female rat pituitary
    Fumi Shimizu
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Int J Dev Neurosci 26:381-4. 2008
    ..Additionally, the reduction of NMU expression in the pituitary may be related to the increases in serum estradiol and insulin levels that occur during the pubertal period, which may negate NMU suppression of gonadotropin secretion...
  32. doi request reprint Neonatal immune challenge affects the regulation of estrus cyclicity and feeding behavior in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 27:111-4. 2009
    ..Increased expression of UCN2 and CRH-R2 might enhance the sensitivity of the estrous cycle in suppressing the effects of LPS...
  33. doi request reprint Delayed puberty in prenatally glucocorticoid administered female rats occurs independently of the hypothalamic Kiss1-Kiss1r-GnRH system
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Int J Dev Neurosci 29:183-8. 2011
    ..These results suggested that the delayed onset of puberty induced by maternal dexamethasone administration would occur independently of hypothalamic Kiss1-Kiss1r-GnRH system...
  34. ncbi request reprint Association of interleukin-8 with hot flashes in premenopausal, perimenopausal, and postmenopausal women and bilateral oophorectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Clin Endocrinol Metab 91:4805-8. 2006
    ..The purpose of this study was to identify serum cytokine concentrations in premenopausal, perimenopausal, and postmenopausal women and bilateral oophorectomized women with hot flashes...
  35. ncbi request reprint Associations of interleukin-6 with interleukin-1beta, interleukin-8 and macrophage inflammatory protein-1beta in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Cytokine 41:302-6. 2008
    ..The aim of the present study was to determine the associations of interleukin (IL)-6 with other cytokines and chemokines and to compare these associations in peri- and postmenopausal women...
  36. ncbi request reprint Effect of vitamin K2 treatment on carboxylation of osteocalcin in early postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Gynecol Endocrinol 22:455-9. 2006
    ....
  37. ncbi request reprint Effect of bed rest during pregnancy on bone turnover markers in pregnant and postpartum women
    Takashi Kaji
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Bone 40:1088-94. 2007
    ....
  38. doi request reprint Changes in the responsiveness of serum leptin and hypothalamic neuropeptide Y mRNA levels to food deprivation in developing rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Int J Dev Neurosci 29:377-80. 2011
    ..These findings indicate that the sensitivity of hypothalamic NPY mRNA expression to food deprivation and hypoleptinemia has developed by postnatal day 25...
  39. ncbi request reprint Association of serum cytokine concentrations with psychological symptoms in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto, Tokushima, Japan
    J Reprod Immunol 75:56-62. 2007
    ..The purpose of the present study was to clarify the association of serum cytokine concentrations, determined using a multiplexed cytokine assay, with psychological symptoms in midlife women...
  40. ncbi request reprint Delay in the onset of puberty of intrauterine growth retarded female rats cannot be rescued with hypernutrition after birth
    Ganbat Gereltsetseg
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Endocr J 59:963-72. 2012
    ..Interestingly, the age of VO did not differ between the IUGR-NN and IUGR-HN groups. In conclusion, maternal undernutrition delays puberty in female offspring, and this delay in puberty cannot be rescued with hypernutrition after birth...
  41. ncbi request reprint Hypothalamic Ghrelin suppresses pulsatile secretion of luteinizing hormone via beta-endorphin in ovariectomized rats
    Rie Ogata
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan r ogata pop21 odn ne jp
    Neuroendocrinology 90:364-70. 2009
    ..We examined the effects of naloxone (NAL), a specific opioid antagonist, on the suppression of pulsatile LH secretion by ghrelin to determine whether beta-endorphin (beta-END) is involved in this suppressive effect...
  42. doi request reprint Induction of circulating monocyte chemoattractant protein-1 in women with gonadotropin-releasing hormone agonist
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    J Reprod Immunol 90:227-34. 2011
    ..We conclude that a hypo-estrogenic state due to administration of a GnRH agonist increases circulating levels of cytokines and chemokines, especially MCP1...
  43. doi request reprint Sensitivities of mRNA expression levels of Kiss1 and its receptor, Kiss1r, to nutritional status are changed during the developmental period in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    J Endocrinol 207:195-202. 2010
    ..These data also show that hypoleptinemia plays a role in the reduction of hypothalamic Kiss1r mRNA expression under subnutritional conditions...
  44. ncbi request reprint Prenatal exposure to glucocorticoids affects body weight, serum leptin levels, and hypothalamic neuropeptide-Y expression in pre-pubertal female rat offspring
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan Electronic address
    Int J Dev Neurosci 36:1-4. 2014
    ....
  45. ncbi request reprint Pre-pubertal serum leptin levels and sensitivity to central leptin injection of prenatally undernourished female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan Electronic address
    Int J Dev Neurosci 35:52-4. 2014
    ..These results suggest that prenatal undernutrition induces leptin resistance until the neonatal to pre-pubertal period and that these alterations might be caused by impaired transportation of leptin to central tissues. ..
  46. ncbi request reprint Effects of raloxifene on the production of cytokines in stimulated whole blood in ex vivo and in vitro studies
    Yuka Kasai
    Department of Obstetrics and Gynecology, Tokushima Prefectural Central Hospital, Tokushima, Japan
    J Med Invest 58:110-7. 2011
    ..The aims of this study were to determine the effects of raloxifene therapy on production of cytokines and in vitro effects of raloxifene on production of cytokines by whole blood cultures...
  47. ncbi request reprint Transition of leptin receptor expression during pubertal development in female rat pituitary
    Fumi Shimizu
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Endocr J 55:191-8. 2008
    ..05, p<0.01, respectively). In conclusion, since the pituitary gonadotroph is a potential target of leptin, the juvenile rat pituitary might prepare for a subsequent increase of serum leptin concentration by expressing Ob-Rb...
  48. ncbi request reprint Androgen in postmenopausal women
    Toshiyuki Yasui
    Department of Reproductive Technology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    J Med Invest 59:12-27. 2012
    ..An appropriate level of androgen may play important roles in metabolic, psychological and sexual functions in women. In addition, the roles of testosterone and DHEA-S in women's health may be different...
  49. ncbi request reprint Reproducibility of luteinizing hormone hypersecretion in different phases of the menstrual cycle in polycystic ovary syndrome
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    J Obstet Gynaecol Res 35:514-9. 2009
    ..Furthermore, we evaluated the influence of cycle days and body mass index on LH levels using different days from menses or withdrawal bleeding...
  50. ncbi request reprint Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Clin Chim Acta 386:69-75. 2007
    ..We examined the relationships of serum adiponectin concentrations with serum concentrations of hormones and SHBG in men and women...
  51. doi request reprint Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats
    Masahiro Murakami
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, Tokushima 770 8503, Japan
    J Endocrinol 199:105-12. 2008
    ..These results suggest that RFRP-3 does not affect LH secretion via the release of GnRH, and that RFRP-3 directly acts upon the pituitary to suppress GnRH-stimulated LH secretion in female rats...
  52. ncbi request reprint Hypothalamic Kiss1 and RFRP gene expressions are changed by a high dose of lipopolysaccharide in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan Electronic address
    Horm Behav 66:309-16. 2014
    ..As reproduction needs a large amount of energy, dysfunction of gonadotropin secretion under immune stress may be a biophylatic mechanism by which more energy is saved for the immune response. ..
  53. pmc Associations of estrogen and testosterone with insulin resistance in pre- and postmenopausal women with and without hormone therapy
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan, Tokushima 770 8503, Japan
    Int J Endocrinol Metab 11:65-70. 2013
    ..However, to date, the associations of estradiol, testosterone and SHBG with insulin resistance according to estrogen level have not been clarified...
  54. doi request reprint Neonatal lipopolysaccharide exposure attenuates the homotypic stress-induced suppression of LH secretion in adulthood in male rat
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 27:345-9. 2009
    ..Attenuation of proinflammatory cytokine synthesis in the hypothalamus might be involved in this alteration...
  55. doi request reprint High adiponectin level in late postmenopausal women with normal renal function
    Sumika Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan Electronic address
    Clin Chim Acta 430:104-8. 2014
    ..We examined whether high circulating adiponectin level is associated with renal function and is favorable for lipid and glucose metabolism in late postmenopausal women with normal renal function...
  56. ncbi request reprint Changes in the responsiveness of hypothalamic prokineticin 2 mRNA expression to food deprivation in developing female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan Electronic address
    Int J Dev Neurosci 34:76-8. 2014
    ..These results suggest that the sensitivity of hypothalamic PK2 expression to undernutrition develops during the early neonatal period, when the responses of other appetite regulatory factors to such pressures remain immature. ..
  57. ncbi request reprint Effect of semen characteristics on pregnancy rate following intrauterine insemination
    Uranchimeg Dorjpurev
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    J Med Invest 58:127-33. 2011
    ..To assess the effects of semen characteristics on the success of intrauterine insemination (IUI)...
  58. doi request reprint FKBP5, SERT and COMT mRNA expressions in the peripheral leukocytes during menstruation cycle in healthy reproductive females
    Sawako Kinouchi
    Department of Psychiatry, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Neurosci Lett 434:124-8. 2008
    ..In conclusion, there are differences of HADS anxiety score and FKBP5 mRNA expression in the leukocytes across the menstrual cycle but there is no correlation between anxiety scores and FKBP5 mRNA...
  59. ncbi request reprint Diagnostic performance of serum total testosterone for Japanese patients with polycystic ovary syndrome
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Endocr J 54:233-8. 2007
    ....
  60. ncbi request reprint Stimulatory effect of the herbal medicine Keishi-bukuryo-gan on a cytokine-induced neutrophil chemoattractant, in rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima 770 8503, Japan
    Am J Reprod Immunol 50:90-7. 2003
    ..The contents of CINC/gro, IL-1beta and TNFalpha in the cultured media were determined by enzyme-linked immunosorbent assay (ELISA)...
  61. ncbi request reprint Circulating osteoprotegerin in women during GnRH-agonist treatment and their relationships with mineral components and biomarkers of bone turnover
    Hirokazu Uemura
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Bone 33:860-6. 2003
    ....
  62. ncbi request reprint The herbal medicine Unkei-to stimulates the secretion of a cytokine-induced neutrophil chemoattractant, CINC/gro, in the rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima, Japan
    Am J Reprod Immunol 49:14-20. 2003
    ....
  63. ncbi request reprint Effects of leptin on gonadotropin secretion in juvenile female rat pituitary cells
    Michiko Tezuka
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, 3 18 15, Kuramoto Cho, Tokushima, 770 8503, Japan
    Eur J Endocrinol 146:261-6. 2002
    ..In a study using adult male or female rats, it was found that leptin stimulated the secretion of gonadotropin directly from the pituitary in a dose-related manner. However, there is no study in juvenile female rats before puberty...
  64. ncbi request reprint Serum estradiol concentration as measured by HPLC-RIA and bone mineral density in postmenopausal women during hormone replacement therapy
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Horm Res 61:117-25. 2004
    ....
  65. ncbi request reprint Myeloid-related protein-8/14 is associated with proinflammatory cytokines in cervical mucus
    Kotaro Kunimi
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Reprod Immunol 71:3-11. 2006
    ..MRP-8/14 was mainly detected in human cervical mucus and showed a positive correlation with proinflammatory cytokines. The MRP-8/14 level in cervical mucus may be useful as a marker of inflammation of the uterine cervix...
  66. doi request reprint Roscovitine in combination with calcium ionophore induces oocyte activation through reduction of M-phase promoting factor activity in mice
    Tomomi Iba
    Graduate School of Health Science, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima, Japan
    Zygote 20:321-5. 2012
    ..Roscovitine with calcium ionophore is effective for induction of oocyte activation through suppression of MPF activity in mice...
  67. ncbi request reprint Does the bromocriptine-rebound method improve embryo quality?
    Naoko Moride
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    J Med Invest 58:63-6. 2011
    ..Both procedures were similar, except that in the BR method, bromocriptine was administered daily from day 5 of the preceding cycle until 7 days before ovarian stimulation...
  68. ncbi request reprint Differences in insulin sensitivity in pregnant women with overweight and gestational diabetes mellitus
    Satoko Endo
    Departments of Obstetrics and Gynecology, The University of Tokushima School of Medicine, Tokushima, Japan
    Gynecol Endocrinol 22:343-9. 2006
    ....
  69. ncbi request reprint Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Maturitas 50:19-29. 2005
    ..The objective of this study was to determine the relationships of serum estrogen levels after hormone replacement therapy (HRT) every other day and every day with body mass index (BMI) in postmenopausal and bilaterally ovariectomized women...