T Yasui

Summary

Affiliation: The University of Tokushima
Country: Japan

Publications

  1. ncbi request reprint The herbal medicine Unkei-to stimulates the secretion of a cytokine-induced neutrophil chemoattractant, CINC/gro, in the rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima, Japan
    Am J Reprod Immunol 49:14-20. 2003
  2. doi request reprint Associations of interleukin-6 with interleukin-1beta, interleukin-8 and macrophage inflammatory protein-1beta in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Cytokine 41:302-6. 2008
  3. ncbi request reprint Differences in sensitivity to cold in Japanese men and postmenopausal women aged > or =50 years
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Gend Med 4:359-66. 2007
  4. doi request reprint Effects of Japanese traditional medicines on circulating cytokine levels in women with hot flashes
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Menopause 18:85-92. 2011
  5. ncbi request reprint Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Clin Chim Acta 386:69-75. 2007
  6. ncbi request reprint Stimulatory effect of the herbal medicine Keishi-bukuryo-gan on a cytokine-induced neutrophil chemoattractant, in rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima 770 8503, Japan
    Am J Reprod Immunol 50:90-7. 2003
  7. ncbi request reprint Association of serum cytokine concentrations with psychological symptoms in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto, Tokushima, Japan
    J Reprod Immunol 75:56-62. 2007
  8. ncbi request reprint Association of serum undercarboxylated osteocalcin with serum estradiol in pre-, peri- and early post-menopausal women
    T Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    J Endocrinol Invest 29:913-8. 2006
  9. ncbi request reprint Serum estradiol concentration as measured by HPLC-RIA and bone mineral density in postmenopausal women during hormone replacement therapy
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Horm Res 61:117-25. 2004
  10. ncbi request reprint Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Maturitas 50:19-29. 2005

Collaborators

Detail Information

Publications74

  1. ncbi request reprint The herbal medicine Unkei-to stimulates the secretion of a cytokine-induced neutrophil chemoattractant, CINC/gro, in the rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima, Japan
    Am J Reprod Immunol 49:14-20. 2003
    ....
  2. doi request reprint Associations of interleukin-6 with interleukin-1beta, interleukin-8 and macrophage inflammatory protein-1beta in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Cytokine 41:302-6. 2008
    ..The aim of the present study was to determine the associations of interleukin (IL)-6 with other cytokines and chemokines and to compare these associations in peri- and postmenopausal women...
  3. ncbi request reprint Differences in sensitivity to cold in Japanese men and postmenopausal women aged > or =50 years
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Gend Med 4:359-66. 2007
    ..However, no previous studies have examined the differences in sensitivity to cold in men and women or the association of hormonal levels with sensitivity to cold...
  4. doi request reprint Effects of Japanese traditional medicines on circulating cytokine levels in women with hot flashes
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Menopause 18:85-92. 2011
    ..The effects of the Japanese traditional medicines keishibukuryogan and kamishoyosan on circulating cytokines were examined to clarify the difference in the actions of Japanese traditional medicines in women with hot flashes...
  5. ncbi request reprint Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Clin Chim Acta 386:69-75. 2007
    ..We examined the relationships of serum adiponectin concentrations with serum concentrations of hormones and SHBG in men and women...
  6. ncbi request reprint Stimulatory effect of the herbal medicine Keishi-bukuryo-gan on a cytokine-induced neutrophil chemoattractant, in rat ovarian cell culture
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima 770 8503, Japan
    Am J Reprod Immunol 50:90-7. 2003
    ..The contents of CINC/gro, IL-1beta and TNFalpha in the cultured media were determined by enzyme-linked immunosorbent assay (ELISA)...
  7. ncbi request reprint Association of serum cytokine concentrations with psychological symptoms in midlife women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Kuramoto, Tokushima, Japan
    J Reprod Immunol 75:56-62. 2007
    ..The purpose of the present study was to clarify the association of serum cytokine concentrations, determined using a multiplexed cytokine assay, with psychological symptoms in midlife women...
  8. ncbi request reprint Association of serum undercarboxylated osteocalcin with serum estradiol in pre-, peri- and early post-menopausal women
    T Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    J Endocrinol Invest 29:913-8. 2006
    ....
  9. ncbi request reprint Serum estradiol concentration as measured by HPLC-RIA and bone mineral density in postmenopausal women during hormone replacement therapy
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Horm Res 61:117-25. 2004
    ....
  10. ncbi request reprint Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Maturitas 50:19-29. 2005
    ..The objective of this study was to determine the relationships of serum estrogen levels after hormone replacement therapy (HRT) every other day and every day with body mass index (BMI) in postmenopausal and bilaterally ovariectomized women...
  11. ncbi request reprint Biological effects of hormone replacement therapy in relation to serum estradiol levels
    T Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokyo, Japan
    Horm Res 56:38-44. 2001
    ....
  12. doi request reprint Association of N-terminal pro B-type natriuretic peptide and sex hormone-binding globulin in non-obese peri- and postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Clin Chim Acta 411:280-4. 2010
    ..We also examined the change in circulating NT-proBNP caused by a gonadotrophin-releasing hormone (GnRH) agonist in order to clarify the effect of acute hormone deficiency on NT-proBNP...
  13. ncbi request reprint Changes in serum cytokine concentrations during the menopausal transition
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, University of Tokushima, Kuramoto cho 3 18 15, Tokushima 770 8503, Japan
    Maturitas 56:396-403. 2007
    ....
  14. doi request reprint Effects of oral and transdermal estrogen therapies on circulating cytokines and chemokines in postmenopausal women with hysterectomy
    Toshiyuki Yasui
    Department of Obstetrics, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima, Japan
    Eur J Endocrinol 161:267-73. 2009
    ....
  15. ncbi request reprint Different effects of oral conjugated equine estrogens and transdermal estrogen on undercarboxylated osteocalcin concentration in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 13:651-9. 2006
    ..We also examined the associations of ucOC concentration with estradiol concentration and TG...
  16. doi request reprint Changes in circulating cytokine levels in midlife women with psychological symptoms with selective serotonin reuptake inhibitor and Japanese traditional medicine
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Course of Human Development, Human Development and Health Science, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Maturitas 62:146-52. 2009
    ....
  17. ncbi request reprint Effect of vitamin K2 treatment on carboxylation of osteocalcin in early postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Gynecol Endocrinol 22:455-9. 2006
    ....
  18. doi request reprint Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Atherosclerosis 204:471-5. 2009
    ..The aim of the present study was to determine the effects of raloxifene on changes in circulating levels of cytokines and chemokines in relation to changes in lipid profiles and markers of inflammation in postmenopausal women...
  19. ncbi request reprint Association of interleukin-8 with hot flashes in premenopausal, perimenopausal, and postmenopausal women and bilateral oophorectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Clin Endocrinol Metab 91:4805-8. 2006
    ..The purpose of this study was to identify serum cytokine concentrations in premenopausal, perimenopausal, and postmenopausal women and bilateral oophorectomized women with hot flashes...
  20. doi request reprint Interleukin-7 is associated with monocyte chemoattractant protein-1 and soluble E-selectin levels in peripheral blood of newly post-menopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Human Development and Health Science, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    J Reprod Immunol 81:97-102. 2009
    ..We conclude that there is a relationship between circulating IL-7, MCP-1 and soluble E-selectin, and that IL-7 may be involved in regulating inflammatory cell adhesion together with MCP-1 and E-selectin in post-menopausal women...
  21. doi request reprint Associations of endogenous sex hormones and sex hormone-binding globulin with lipid profiles in aged Japanese men and women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Clin Chim Acta 398:43-7. 2008
    ..We determined the associations of serum estradiol level and free estradiol index (FEI) with lipid profiles and insulin resistance in aged Japanese men and women...
  22. ncbi request reprint Change in serum undercarboxylated osteocalcin concentration in bilaterally oophorectomized women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Maturitas 56:288-96. 2007
    ..We investigated changes in serum undercarboxylated osteocalcin (ucOC) concentrations, bone turnover markers and spine bone mineral density (BMD) in women who had undergone bilateral oophorectomy during the premenopausal period...
  23. ncbi request reprint Effects of postmenopausal hormone therapy every day and every other day on lipid levels according to difference in body mass index
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 12:223-31. 2005
    ....
  24. ncbi request reprint Transient increase in the levels of T-helper 1 cytokines in postmenopausal women and the effects of hormone replacement therapy
    M Kamada
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Gynecol Obstet Invest 52:82-8. 2001
    ..HRT prevents this increase, thereby improving the aberration of Th1/Th2 balance that is implicated in an inadequate immune response and pathological conditions...
  25. ncbi request reprint Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis
    M Irahara
    Department of Obstetrics and Gynecology, University of Tokushima, School of Medicine, Tokushima, Japan
    Gynecol Obstet Invest 52:217-22. 2001
    ..These findings led to a conclusion that GnRH-a therapy added back by every-other-day administration of 0.625 mg CEE and 2.5 mg MPA was a safe and effective treatment for Japanese women with endometriosis...
  26. ncbi request reprint Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand in post-menopausal women
    H Uemura
    Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, 770 8503 Japan
    J Endocrinol Invest 31:163-8. 2008
    ..The aim of this study was to elucidate the detail profiles of circulating osteoprotegerin (OPG) and soluble receptor activator of nuclear factor kappaB ligand (sRANKL) in post-menopausal women...
  27. ncbi request reprint Postmenopausal changes in production of type 1 and type 2 cytokines and the effects of hormone replacement therapy
    K Deguchi
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan
    Menopause 8:266-73. 2001
    ..CONCLUSIONS: Production of IL-10 is augmented in postmenopausal women. HRT probably prevents postmenopausal women from an aberration of the immune system by improving the balance of type 1 and type 2 immune reactions...
  28. ncbi request reprint Postmenopausal changes in serum cytokine levels and hormone replacement therapy
    M Kamada
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, and the Cellular Technology Institute, Otsuka Pharmaceutical Company, Ltd, Tokushima, Japan
    Am J Obstet Gynecol 184:309-14. 2001
    ..Inducing the production of macrophage colony-stimulating factor is a possible additional mechanism of hormone replacement therapy in mediating the antiatherogenic effect...
  29. ncbi request reprint B cell subsets in postmenopausal women and the effect of hormone replacement therapy
    M Kamada
    Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, 3 18 15 Kuramoto cho, 770 8503, Tokushima, Japan
    Maturitas 37:173-9. 2001
    ..The effect of hormone replacement therapy (HRT) on B cell subsets was examined to establish whether the administration of gonadal hormones influence humoral immunity in postmenopausal women...
  30. ncbi request reprint Effect of hormone replacement therapy on the production of bone-resorbing cytokines by peripheral blood cells in postmenopausal women
    H Uemura
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Horm Metab Res 37:226-30. 2005
    ..These results show that estrogen decreases the accelerated production of IL-1beta and reduces the production of TNFalpha in postmenopausal women at each postmenopausal stage, even in late-postmenopausal women...
  31. ncbi request reprint Close correlation between estrogen treatment and renal phosphate reabsorption capacity
    H Uemura
    Department of Obstetrics and Gynecology, The University of Tokushima, School of Medicine, Japan
    J Clin Endocrinol Metab 85:1215-9. 2000
    ..These results suggest that estrogen could act directly to suppress sodium-dependent Pi reabsorption in the renal proximal tubules...
  32. ncbi request reprint Lipolytic activity of anemia-inducing substance from tumor-bearing rabbits
    O Ishiko
    Department of Obstetrics and Gynecology, Osaka City University Medical School, Japan
    Nutr Cancer 33:201-5. 1999
    ..These results strongly suggest that AIS might be one of the substances involved in the enhanced lipolytic activity in advanced tumor-bearing subjects...
  33. ncbi request reprint Decreased expression of kisspeptin mediates acute immune/inflammatory stress-induced suppression of gonadotropin secretion in female rat
    T Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Endocrinol Invest 31:656-9. 2008
    ..These results suggest that KiSS-1 systems are sensitive to immune/inflammatory challenge conditions and transmit these signals into the central reproductive system...
  34. ncbi request reprint Effects of leptin on secretion of LH and FSH from primary cultured female rat pituitary cells
    K Ogura
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, 3-18-15, Kuramoto-cho, Tokushima City, Tokushima 770-8503, Japan
    Eur J Endocrinol 144:653-8. 2001
    ..Leptin may be involved in the onset of puberty. It is also conceivable that leptin may be a cause of ovulatory failure, not only in weight loss but also in weight gain...
  35. ncbi request reprint Regulatory factors on parathyroid hormone-related peptide production by primary culture of lactating rat mammary gland
    H Uemura
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, 3 18 15 Kuramoto cho, Tokushima, Japan
    Horm Metab Res 37:463-7. 2005
    ..Progesterone dramatically falls after delivery, thus possibly accelerating PTHrP production by lactating mammary glands and resulting in considerable amounts of PTHrP secreted into the milk...
  36. ncbi request reprint Orexin-A suppresses the pulsatile secretion of luteinizing hormone via beta-endorphin
    M Irahara
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, Tokushima, Japan
    Biochem Biophys Res Commun 281:232-6. 2001
    ..These results indicate that orexin-A, but not orexin-B, suppresses GnRH secretion via beta-endorphin...
  37. ncbi request reprint [Clinical application of undercarboxylated osteocalcin]
    Toshiyuki Yasui
    The University of Tokushima Graduate School, Institutes of Health Biosciences, Department of Obstetrics and Gynecology
    Clin Calcium 17:1709-16. 2007
    ..Additionally, the effect of HT with transdermal estradiol on ucOC concentration in women is weaker than the effect of HT with oral CEE...
  38. pmc Effects of intrauterine undernutrition on hypothalamic Kiss1 expression and the timing of puberty in female rats
    T Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Physiol 588:821-9. 2010
    ..Increased leptin resistance in the kisspeptin system might be involved in these alterations...
  39. ncbi request reprint Serum osteoprotegerin/osteoclastogenesis-inhibitory factor during pregnancy and lactation and the relationship with calcium-regulating hormones and bone turnover markers
    H Uemura
    Department of Obstetrics and Gynecology, University of Tokushima, School of Medicine, 3 18 15, Kuramoto Cho, Tokushima 770 8503, Japan
    J Endocrinol 174:353-9. 2002
    ..87+/-0.27 ng/ml at 4 days postpartum and had fallen further by 1 month postpartum. These results suggest that the fall in OPG/OCIF levels may be partially connected with the marked acceleration of bone resorption after delivery...
  40. ncbi request reprint The type 2 corticotrophin-releasing hormone receptor mediates orexin A-induced luteinising hormone suppression in ovariectomised rats
    T Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Neuroendocrinol 19:732-8. 2007
    ..These findings suggest that CRH-R2 mediates orexin A-induced LH suppression and it is possible that CRH and UcnII in the hypothalamus are involved in this pathway...
  41. ncbi request reprint Expression of ovarian prolactin receptor in relation to hormonal changes during induction of ovulation in the rat
    H Kinoshita
    Department of Obstetrics and Gynecology, The University of Tokushima, School of Medicine, Tokushima, Japan
    Gynecol Obstet Invest 52:132-8. 2001
    ..It is thought that the long form of PRLR mRNA is involved in folliculogenesis, while the short form of PRLR mRNA may play an important role in the formation and maintenance of the corpus luteum in the rat ovulatory cycle...
  42. ncbi request reprint Differences in insulin sensitivity in pregnant women with overweight and gestational diabetes mellitus
    Satoko Endo
    Departments of Obstetrics and Gynecology, The University of Tokushima School of Medicine, Tokushima, Japan
    Gynecol Endocrinol 22:343-9. 2006
    ....
  43. ncbi request reprint Hormone replacement therapy in postmenopausal women
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, The University of Tokushima School of Medicine, Tokushima, Japan
    J Med Invest 50:136-45. 2003
    ..Selection of the most appropriate regimen of HRT (dose, route of administration and schedule) for the needs of the individual are important factors to increase the rate of continuation with HRT...
  44. doi request reprint Associations of circulating adiponectin with estradiol and monocyte chemotactic protein-1 in postmenopausal women
    Yuka Miyatani
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Menopause 15:536-41. 2008
    ..In addition, the associations of serum adiponectin with serum concentrations of proinflammatory and anti-inflammatory cytokines were examined in women during the menopausal transition...
  45. doi request reprint Difference in the ratio of high-molecular weight (HMW) to total adiponectin and HMW adiponectin in late post-menopausal women
    S Matsui
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    J Endocrinol Invest 36:982-5. 2013
    ..We examined the changes in circulating levels of HMWadiponectin and ratios of HMWto total adiponectin in women during the menopausal transition...
  46. ncbi request reprint Effect of bed rest during pregnancy on bone turnover markers in pregnant and postpartum women
    Takashi Kaji
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Bone 40:1088-94. 2007
    ....
  47. doi request reprint Neonatal lipopolysaccharide exposure attenuates the homotypic stress-induced suppression of LH secretion in adulthood in male rat
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 27:345-9. 2009
    ..Attenuation of proinflammatory cytokine synthesis in the hypothalamus might be involved in this alteration...
  48. doi request reprint Neonatal immune challenge affects the regulation of estrus cyclicity and feeding behavior in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 27:111-4. 2009
    ..Increased expression of UCN2 and CRH-R2 might enhance the sensitivity of the estrous cycle in suppressing the effects of LPS...
  49. ncbi request reprint Undercarboxylated osteocalcin concentration in postmenopausal women receiving hormone therapy daily and on alternate days
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima, Japan
    Menopause 13:314-22. 2006
    ....
  50. ncbi request reprint Randomized trial comparing low-dose hormone replacement therapy and HRT plus 1alpha-OH-vitamin D3 (alfacalcidol) for treatment of postmenopausal bone loss
    Hideki Mizunuma
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    J Bone Miner Metab 24:11-5. 2006
    ..It suggests that the combination therapy can be considered to be a promising mode of treatment for bone loss after menopause...
  51. ncbi request reprint Circulating osteoprotegerin in women during GnRH-agonist treatment and their relationships with mineral components and biomarkers of bone turnover
    Hirokazu Uemura
    Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Tokushima 770 8503, Japan
    Bone 33:860-6. 2003
    ....
  52. doi request reprint Hypothalamic Ghrelin suppresses pulsatile secretion of luteinizing hormone via beta-endorphin in ovariectomized rats
    Rie Ogata
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan r ogata pop21 odn ne jp
    Neuroendocrinology 90:364-70. 2009
    ..We examined the effects of naloxone (NAL), a specific opioid antagonist, on the suppression of pulsatile LH secretion by ghrelin to determine whether beta-endorphin (beta-END) is involved in this suppressive effect...
  53. doi request reprint Reproducibility of luteinizing hormone hypersecretion in different phases of the menstrual cycle in polycystic ovary syndrome
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    J Obstet Gynaecol Res 35:514-9. 2009
    ..Furthermore, we evaluated the influence of cycle days and body mass index on LH levels using different days from menses or withdrawal bleeding...
  54. doi request reprint Neonatal LPS injection alters the body weight regulation systems of rats under non-stress and immune stress conditions
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Int J Dev Neurosci 28:119-24. 2010
    ..Changes in the endocrine, neuropeptide, and cytokine regulation systems might be involved in these alterations...
  55. doi request reprint Estradiol suppresses NMU mRNA expression during sexual maturation in the female rat pituitary
    Fumi Shimizu
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Int J Dev Neurosci 26:381-4. 2008
    ..Additionally, the reduction of NMU expression in the pituitary may be related to the increases in serum estradiol and insulin levels that occur during the pubertal period, which may negate NMU suppression of gonadotropin secretion...
  56. ncbi request reprint Myeloid-related protein-8/14 is associated with proinflammatory cytokines in cervical mucus
    Kotaro Kunimi
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770 8503, Japan
    J Reprod Immunol 71:3-11. 2006
    ..MRP-8/14 was mainly detected in human cervical mucus and showed a positive correlation with proinflammatory cytokines. The MRP-8/14 level in cervical mucus may be useful as a marker of inflammation of the uterine cervix...
  57. ncbi request reprint Circulating osteoprotegerin is associated with age and systolic blood pressure, but not with lipid profile or fasting glucose, in postmenopausal women
    Hirokazu Uemura
    Department of Preventive Medicine, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Menopause 15:180-4. 2008
    ..The aim of this study was to clarify the relationships between circulating OPG and the risk factors for vascular disorders in postmenopausal women...
  58. ncbi request reprint Effects of leptin on gonadotropin secretion in juvenile female rat pituitary cells
    Michiko Tezuka
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, 3 18 15, Kuramoto Cho, Tokushima, 770 8503, Japan
    Eur J Endocrinol 146:261-6. 2002
    ..In a study using adult male or female rats, it was found that leptin stimulated the secretion of gonadotropin directly from the pituitary in a dose-related manner. However, there is no study in juvenile female rats before puberty...
  59. doi request reprint Delayed puberty in prenatally glucocorticoid administered female rats occurs independently of the hypothalamic Kiss1-Kiss1r-GnRH system
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Int J Dev Neurosci 29:183-8. 2011
    ..These results suggested that the delayed onset of puberty induced by maternal dexamethasone administration would occur independently of hypothalamic Kiss1-Kiss1r-GnRH system...
  60. ncbi request reprint Late recurrence of malignant melanoma mimicking primary peritoneal cancer
    M Sano
    Department of Obstetrics and Gynecology, Osaka City University, Graduate School of Medicine, Osaka, Japan
    Eur J Gynaecol Oncol 34:265-8. 2013
    ..Malignant melanoma is an extremely malignant tumor with an unpredictable metastatic profile with variable periods of remission...
  61. ncbi request reprint The obesity in bilateral ovariectomized rats is related to a decrease in the expression of leptin receptors in the brain
    Mitsuhiro Kimura
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, Tokushima, Japan
    Biochem Biophys Res Commun 290:1349-53. 2002
    ....
  62. ncbi request reprint Comparison and problems of measured values of LH, FSH, and PRL among measurement systems
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, University of Tokushima School of Medicine, Japan
    Endocr J 53:101-9. 2006
    ..96-0.99, but the value showed large differences among the systems. For the diagnosis of hyperprolactinemia, the higher limit of the normal range may be 15 ng/mL for SPAC-S, 30 ng/mL for ARCHITECT, and 24 ng/mL for Centaur...
  63. ncbi request reprint Transition of leptin receptor expression during pubertal development in female rat pituitary
    Fumi Shimizu
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Endocr J 55:191-8. 2008
    ..05, p<0.01, respectively). In conclusion, since the pituitary gonadotroph is a potential target of leptin, the juvenile rat pituitary might prepare for a subsequent increase of serum leptin concentration by expressing Ob-Rb...
  64. ncbi request reprint Chemotherapy-related hypersensitivity reaction in Japanese patients with gynecologic malignancy
    K Kitada
    Department of Obstetrics and Gynecology, Osaka City University, Graduate School of Medicine, Osaka, Japan
    Eur J Gynaecol Oncol 33:252-4. 2012
    ..Chemotherapy-related hypersensitivity reaction seems to be problematic in the safe management of chemotherapy. In this study we investigated chemotherapy-related hypersensitivity reaction in patients with gynecologic malignancy...
  65. ncbi request reprint Probucol decreases total body fat loss in VX2-carcinoma-induced cachectic rabbits
    Y Hyun
    Department of Obstetrics and Gynecology, Osaka City University Medical School, Abeno-ku, Osaka 545-8585, Japan
    Oncol Rep 8:1309-11. 2001
    ..Similarly serum lipolytic activity showed no differences, whether probucol was administered or not, while the decrease in total body fat was significantly less when probucol was administered...
  66. doi request reprint FKBP5, SERT and COMT mRNA expressions in the peripheral leukocytes during menstruation cycle in healthy reproductive females
    Sawako Kinouchi
    Department of Psychiatry, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    Neurosci Lett 434:124-8. 2008
    ..In conclusion, there are differences of HADS anxiety score and FKBP5 mRNA expression in the leukocytes across the menstrual cycle but there is no correlation between anxiety scores and FKBP5 mRNA...
  67. ncbi request reprint Diagnostic performance of serum total testosterone for Japanese patients with polycystic ovary syndrome
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Endocr J 54:233-8. 2007
    ....
  68. doi request reprint Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats
    Masahiro Murakami
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School, Institute of Health Biosciences, Tokushima 770 8503, Japan
    J Endocrinol 199:105-12. 2008
    ..These results suggest that RFRP-3 does not affect LH secretion via the release of GnRH, and that RFRP-3 directly acts upon the pituitary to suppress GnRH-stimulated LH secretion in female rats...
  69. doi request reprint MAPKs, activator protein-1 and nuclear factor-κB mediate production of interleukin-1β-stimulated cytokines, prostaglandin E₂ and MMP-1 in human periodontal ligament cells
    R Murayama
    Department of Periodontology, Showa University, School of Dentistry, Tokyo, Japan
    J Periodontal Res 46:568-75. 2011
    ....
  70. ncbi request reprint Vascular endothelial growth factor in monochorionic twins with twin-twin transfusion syndrome
    M Morine
    Department of Obstetrics and Gynecology, University of Tokushima, School of Medicine, Tokushima, Japan
    J Endocrinol Invest 31:966-70. 2008
    ....
  71. ncbi request reprint [Prolactin in reproduction]
    Toshiyuki Yasui
    Department of Obstetrics and Gynecology, The University of Tokushima Graduate School
    Nihon Rinsho 64:258-63. 2006
  72. doi request reprint Sensitivities of mRNA expression levels of Kiss1 and its receptor, Kiss1r, to nutritional status are changed during the developmental period in female rats
    Takeshi Iwasa
    Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
    J Endocrinol 207:195-202. 2010
    ..These data also show that hypoleptinemia plays a role in the reduction of hypothalamic Kiss1r mRNA expression under subnutritional conditions...
  73. doi request reprint Involvement of cytokine-induced neutrophil chemoattractant in hypothalamic thermoregulation of luteinizing hormone-releasing hormone
    Masamichi Noguchi
    Tsumura Research Laboratory, 3586 Yoshiwara, Ami Machi, Inashiki Gun, Ibaraki 300 1192, Japan
    Endocrinology 149:2899-906. 2008
    ..Disturbance of the thermoregulatory mechanism involving LHRH and CINC may be related to the pathoetiology of hot flashes...
  74. ncbi request reprint [Successfully treated case with microscopic polyangiitis complicated severe varicella zoster virus infection including encephalitis and disseminated varicella zoster]
    Junko Matsumoto
    Division of Rheumatic Diseases, Tokyo Metropolitan Otsuka Hospital, Tokyo
    Ryumachi 43:703-9. 2003
    ..Combination of corticosteroid and acyclovir therapies for MPA and varicella zoster encephalitis under hemodialysis were successful. The diagnostic process and therapies to these complicated contexts were thought to be very important...