Keitarou Saiki

Summary

Affiliation: The Nippon Dental University
Country: Japan

Publications

  1. ncbi request reprint Identification of a Porphyromonas gingivalis novel protein sov required for the secretion of gingipains
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Chiyoda ku, Tokyo 102 8159, Japan
    Microbiol Immunol 51:483-91. 2007
  2. ncbi request reprint Deletion and purification studies to elucidate the structure of the Actinobacillus actinomycetemcomitans cytolethal distending toxin
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Dentistry at Tokyo, Chiyoda ku, Tokyo 102 8159, Japan
    J Biochem 136:335-42. 2004
  3. doi request reprint The role of Sov protein in the secretion of gingipain protease virulence factors of Porphyromonas gingivalis
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 302:166-74. 2010
  4. doi request reprint Identification of a novel Porphyromonas gingivalis outer membrane protein, PG534, required for the production of active gingipains
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 310:168-74. 2010
  5. doi request reprint PG27 is a novel membrane protein essential for a Porphyromonas gingivalis protease secretion system
    Ikumi Ishiguro
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 292:261-7. 2009
  6. ncbi request reprint [Structure, function, and stability of cytolethal distending toxin]
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University, School of Life Dentistry at Tokyo, Fujimi 1 9 20, Tokyo 102 8159, Japan
    Seikagaku 79:350-4. 2007
  7. pmc Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans
    Taro Yamada
    Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045 7534, USA
    Protein Sci 15:362-72. 2006
  8. pmc p53-independent expression of p21(CIP1/WAF1) in plasmacytic cells during G(2) cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin
    Tsuyoshi Sato
    Department of Oral Science, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    Infect Immun 70:528-34. 2002

Collaborators

  • Kiyoshi Konishi
  • Ikumi Ishiguro
  • Taro Yamada
  • Tsuyoshi Sato
  • Fusao Takusagawa
  • Junichi Komoto
  • Isao Ishikawa
  • Tatsuji Nishihara
  • Masanosuke Yoshikawa
  • Kenji Yamato
  • Takeyoshi Koseki

Detail Information

Publications8

  1. ncbi request reprint Identification of a Porphyromonas gingivalis novel protein sov required for the secretion of gingipains
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Chiyoda ku, Tokyo 102 8159, Japan
    Microbiol Immunol 51:483-91. 2007
    ..Taken together, our findings indicated that Sov is a novel protein required for the secretion of gingipains and suggested that the secretion system for gingipains is different from the conserved secretion systems...
  2. ncbi request reprint Deletion and purification studies to elucidate the structure of the Actinobacillus actinomycetemcomitans cytolethal distending toxin
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Dentistry at Tokyo, Chiyoda ku, Tokyo 102 8159, Japan
    J Biochem 136:335-42. 2004
    ..Furthermore, this study describes an effective protocol for the purification of a native rather than reconstituted CDT, and clarifies the subunit composition of the active CDT holotoxin...
  3. doi request reprint The role of Sov protein in the secretion of gingipain protease virulence factors of Porphyromonas gingivalis
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 302:166-74. 2010
    ..In conclusion, we found that Sov is an outer membrane protein participating in the secretion of gingipains and that the C-terminal region of Sov is exposed to the extracellular milieu and involved in the modulation of Sov function...
  4. doi request reprint Identification of a novel Porphyromonas gingivalis outer membrane protein, PG534, required for the production of active gingipains
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 310:168-74. 2010
    ..Subcellular fractionation and immunoblot analysis using anti-PG534 antiserum localized PG534 to the outer membrane. In conclusion, we identified PG534 as a novel outer membrane protein required for the biogenesis of gingipains...
  5. doi request reprint PG27 is a novel membrane protein essential for a Porphyromonas gingivalis protease secretion system
    Ikumi Ishiguro
    Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo, Japan
    FEMS Microbiol Lett 292:261-7. 2009
    ..Taken together, we suggest that PG27 is a unique membrane protein essential for a novel secretion pathway...
  6. ncbi request reprint [Structure, function, and stability of cytolethal distending toxin]
    Keitarou Saiki
    Department of Microbiology, Nippon Dental University, School of Life Dentistry at Tokyo, Fujimi 1 9 20, Tokyo 102 8159, Japan
    Seikagaku 79:350-4. 2007
  7. pmc Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans
    Taro Yamada
    Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045 7534, USA
    Protein Sci 15:362-72. 2006
    ..Another analysis of crystal structures of aCDT and hCDT suggests that the receptor contact area is in the deep groove between CdtA and CdtC, and the characteristic "aromatic patch" on CdtA...
  8. pmc p53-independent expression of p21(CIP1/WAF1) in plasmacytic cells during G(2) cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin
    Tsuyoshi Sato
    Department of Oral Science, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    Infect Immun 70:528-34. 2002
    ....