Y Nakaya

Summary

Affiliation: The University of Tokushima
Country: Japan

Publications

  1. ncbi request reprint BCAA-enriched snack improves nutritional state of cirrhosis
    Yutaka Nakaya
    University of Tokushima Graduate School, Tokushima, Japan
    Nutrition 23:113-20. 2007
  2. ncbi request reprint Cilostazol, a phosphodiesterase inhibitor, improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty Rat, a model of spontaneous NIDDM
    Y Nakaya
    Department of Nutrition, School of Medicine, University of Tokushima, Tokushima City, Japan
    Diabetes Obes Metab 1:37-41. 1999
  3. ncbi request reprint Taurine improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2 diabetes
    Y Nakaya
    Department of Nutrition, Tokushima University, School of Medicine, Tokushima, Japan
    Am J Clin Nutr 71:54-8. 2000
  4. ncbi request reprint Respiratory quotient in patients with non-insulin-dependent diabetes mellitus treated with insulin and oral hypoglycemic agents
    Y Nakaya
    Department of Nutrition, University of Tokushima, School of Medicine, Aichi Medical School, Tokushima, Japan
    Ann Nutr Metab 42:333-40. 1998
  5. ncbi request reprint Does prolonged exercise alter diet-induced thermogenesis?
    M Ohnaka
    Department of Nutrition, School of Medicine, Faculty of Integrated Arts, University of Tokushima, Japan
    Ann Nutr Metab 42:311-8. 1998
  6. ncbi request reprint Is autonomic dysfunction a necessary condition for chronic peptic ulcer formation?
    M Nomura
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    Aliment Pharmacol Ther 14:82-6. 2000
  7. ncbi request reprint Age-related changes in the magnitude of ventricular depolarization vector: analyses by magnetocardiogram
    H Miyajima
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    J Electrocardiol 33:31-5. 2000
  8. ncbi request reprint The nutritional status of elderly bed-ridden patients receiving tube feeding
    K Okada
    Department of Nutrition, School of Medicine, University of Tokushima, Japan
    J Nutr Sci Vitaminol (Tokyo) 47:236-41. 2001
  9. ncbi request reprint Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats
    K Ishizawa
    Department of Pharmacology, University of Tokushima School of Medicine, 3-18-15 Kuramoto, 770-8503, Tokushima, Japan
    Eur J Pharmacol 430:359-67. 2001
  10. ncbi request reprint Activation of Ca2+-activated K+ channels in human myometrium by nitric oxide
    M Shimano
    Department of Obstetrics and Gynecology, Tokushima University, Tokushima, Japan
    Gynecol Obstet Invest 49:249-54. 2000

Collaborators

Detail Information

Publications34

  1. ncbi request reprint BCAA-enriched snack improves nutritional state of cirrhosis
    Yutaka Nakaya
    University of Tokushima Graduate School, Tokushima, Japan
    Nutrition 23:113-20. 2007
    ....
  2. ncbi request reprint Cilostazol, a phosphodiesterase inhibitor, improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty Rat, a model of spontaneous NIDDM
    Y Nakaya
    Department of Nutrition, School of Medicine, University of Tokushima, Tokushima City, Japan
    Diabetes Obes Metab 1:37-41. 1999
    ..The present study aimed to clarify whether cilostazol, a phosphodiesterase inhibitor, improves insulin sensitivity in a model of spontaneous non-insulin dependent diabetes mellitus (NIDDM), Otsuka Long-Evans Tokushima Fatty (OLETF) rat...
  3. ncbi request reprint Taurine improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2 diabetes
    Y Nakaya
    Department of Nutrition, Tokushima University, School of Medicine, Tokushima, Japan
    Am J Clin Nutr 71:54-8. 2000
    ..However, taurine also increases the excretion of cholesterol via conversion to bile acid and would be expected to improve insulin resistance...
  4. ncbi request reprint Respiratory quotient in patients with non-insulin-dependent diabetes mellitus treated with insulin and oral hypoglycemic agents
    Y Nakaya
    Department of Nutrition, University of Tokushima, School of Medicine, Aichi Medical School, Tokushima, Japan
    Ann Nutr Metab 42:333-40. 1998
    ..These results suggest that a high RQ results from excess insulin and excess food. The RQ is a good predictor of weight gain in diabetic patients treated with either insulin or oral hypoglycemic agents...
  5. ncbi request reprint Does prolonged exercise alter diet-induced thermogenesis?
    M Ohnaka
    Department of Nutrition, School of Medicine, Faculty of Integrated Arts, University of Tokushima, Japan
    Ann Nutr Metab 42:311-8. 1998
    ..05). These findings suggest that changes in DIT are affected by many factors and may be related to the balance between these counteracting factors...
  6. ncbi request reprint Is autonomic dysfunction a necessary condition for chronic peptic ulcer formation?
    M Nomura
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    Aliment Pharmacol Ther 14:82-6. 2000
    ..The relationship between 1/f fluctuation of the heart rate variability and Helicobacter pylori infection was evaluated, in order to clarify whether autonomic nervous dysfunction is a necessary condition for chronic peptic ulcer formation...
  7. ncbi request reprint Age-related changes in the magnitude of ventricular depolarization vector: analyses by magnetocardiogram
    H Miyajima
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    J Electrocardiol 33:31-5. 2000
    ..The results additionally suggest that no effects of aging were observed in the actual heart current of the heart during the depolarization phase...
  8. ncbi request reprint The nutritional status of elderly bed-ridden patients receiving tube feeding
    K Okada
    Department of Nutrition, School of Medicine, University of Tokushima, Japan
    J Nutr Sci Vitaminol (Tokyo) 47:236-41. 2001
    ..These findings raise a problem concerning nutritional management of bed-ridden patients...
  9. ncbi request reprint Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats
    K Ishizawa
    Department of Pharmacology, University of Tokushima School of Medicine, 3-18-15 Kuramoto, 770-8503, Tokushima, Japan
    Eur J Pharmacol 430:359-67. 2001
    ..The enhancing effect of angiotensin AT(1) receptor antagonist on skeletal muscle glucose uptake may be attributable to MAP kinase activation or other mechanisms rather than phosphatidylinositol 3-kinase activation...
  10. ncbi request reprint Activation of Ca2+-activated K+ channels in human myometrium by nitric oxide
    M Shimano
    Department of Obstetrics and Gynecology, Tokushima University, Tokushima, Japan
    Gynecol Obstet Invest 49:249-54. 2000
    ..These results indicate that nitric oxide should control human myometrial relaxation during pregnancy via activation of Ca2+-activated K+ channels...
  11. ncbi request reprint Age-related endothelium-dependent vascular relaxation in rat thoracic aorta in response to colforsin
    K Mori
    Department of Pediatrics, School of Medicine, University of Tokushima, Japan
    Pediatr Int 41:673-81. 1999
    ..However, it is not known whether colforsin causes nitric oxide (NO) release and enhances endothelium-dependent vascular relaxation...
  12. ncbi request reprint Involvement of Ca2+ -activated K+ channels in ginsenosides-induced aortic relaxation in rats
    Z Li
    Department of Nutrition, School of Medicine, The University of Tokushima, Tokushima City, Japan
    J Cardiovasc Pharmacol 37:41-7. 2001
    ..In addition, the GS-induced activity of KCa channels was partially inhibited by MB or H-8. These results indicate that the activation of KCa channels involved, at least in part, the GS-induced vasorelaxation of rat aorta...
  13. ncbi request reprint Involvement of adenosine in vascular contractile preconditioning
    N Harada
    Department of Nutrition, School of Medicine, University of Tokushima, Tokushima City, 770-8503 Japan
    Am J Physiol Heart Circ Physiol 280:H2911-9. 2001
    ..Our results suggest that during vasocontraction, endothelium-derived adenosine acquires an ability to protect vascular tone against subsequent repeated contractions by mediating a delayed, possibly indirect, opening of K(ATP) channels...
  14. doi request reprint Cortactin, an actin binding protein, regulates GLUT4 translocation via actin filament remodeling
    H Nazari
    Department of Nutrition and Metabolism, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan
    Biochemistry (Mosc) 76:1262-9. 2011
    ....
  15. ncbi request reprint Relationship among gastric motility, autonomic activity, and portal hemodynamics in patients with liver cirrhosis
    H Miyajima
    Second Department of Internal Medicine; Department of Radiology and; Department of Nutrition, University of Tokushima, Tokushima, Japan
    J Gastroenterol Hepatol 16:647-59. 2001
    ..In addition, gastric motility was decreased, at least in part, by the ingestion of food in cirrhotic patients because of abnormalities in autonomic functions and portal blood flow following a meal...
  16. ncbi request reprint Impaired retention of technetium-99m tetrofosmin in hypertrophic cardiomyopathy
    S Morishita
    Second Department of Internal Medicine, University of Tokushima, Japan
    Am J Cardiol 87:743-7. 2001
    ..The dysfunction of myocardial cells was limited to the hypertrophied region in the apical HC group...
  17. ncbi request reprint Impairment of gastrointestinal motility by nitrate administration: evaluation based on electrogastrographic changes and autonomic nerve activity
    M Nomura
    Department of Digestive Medicine, School of Medicine, Graduate School University of Tokushima, Tokushima, Japan
    Aliment Pharmacol Ther 20:118-24. 2004
    ..Nitrates decrease the tone of the lower oesophageal sphincter, and may thus induce gastro-oesophageal reflux...
  18. ncbi request reprint Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein
    A Takahashi
    Department of Nutrition, School of Medicine, University of Tokushima, Japan
    FEBS Lett 508:484-8. 2001
    ..We conclude that FliC increased [Ca(2+)](in) via inositol 1,4,5-trisphosphate, which was followed by up-regulating hBD-2 mRNA expression via an NF-kappaB-dependent pathway...
  19. ncbi request reprint Blockade of adenosine triphosphate-sensitive potassium channels by thiamylal in rat ventricular myocytes
    Y Tsutsumi
    Department of Anesthesiology, Tokushima University School of Medicine, Japan
    Anesthesiology 92:1154-9. 2000
    ..This study investigated the effects of thiamylal on the activities of KATP channels in isolated rat ventricular myocytes during simulated ischemia...
  20. ncbi request reprint Lidocaine and mexiletine inhibit mitochondrial oxidation in rat ventricular myocytes
    Y Tsutsumi
    Department of Anesthesiology, Tokushima University School of Medicine, Japan
    Anesthesiology 95:766-70. 2001
    ..Because both lidocaine and mexiletine are frequently used antiarrhythmic drugs during myocardial ischemia, it is important to investigate whether they affect mitochondrial K(ATP) channel activities...
  21. ncbi request reprint Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil
    M Li
    Department of Dermatology, School of Medicine, The University of Tokushima, Tokushima, Japan
    J Invest Dermatol 117:1594-600. 2001
    ....
  22. ncbi request reprint Evaluation of the total health promotion plan in Japan, as related to health promotion effects and the prevention of lifestyle-related diseases
    R Oura
    Second Department of Internal Medicine, Tokushima Industrial Promotion Center, University of Tokushima, Japan
    J Med 32:365-79. 2001
    ..These results suggest that such efforts may help prevent the development of lifestyle-related diseases...
  23. ncbi request reprint Autonomic nervous activity before and after eradication of Helicobacter pylori in patients with chronic duodenal ulcer
    K Katoh
    Second Department of Internal Medicine, and Department of Nutrition, School of Medicine, University of Tokushima, Kuramoto Cho, Tokushima, Japan
    Aliment Pharmacol Ther 16:180-6. 2002
    ..Helicobacter pylori infection is involved in the formation of chronic peptic ulcer. However, a previously reported hypothesis concerning the involvement of central autonomic nervous disorder in this condition cannot be ruled out...
  24. ncbi request reprint Autonomic nervous function in patients with peptic ulcer studied by spectral analysis of heart rate variability
    T Nada
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    J Med 32:333-47. 2001
    ..These results suggest that the nocturnal acceleration of LF, HF, and LF/HF is related to peptic ulcer diseases...
  25. ncbi request reprint Novel 31-amino-acid-length endothelins cause constriction of vascular smooth muscle
    F Kishi
    School of Medicine, University of Tokushima, Tokushima, 770, Japan
    Biochem Biophys Res Commun 248:387-90. 1998
    ..Therefore, trachea-constricting peptides ETs(1-31) play roles as vasoconstrictors in a different manner from ETs(1-21)...
  26. ncbi request reprint Lactate stimulates insulin secretion without blocking the K+ channels in HIT-T15 insulinoma cells
    H Akiyoshi
    Department of Nutrition, School of Medicine, The University of Tokushima, Tokushima City, Japan
    Horm Metab Res 31:257-61. 1999
    ..These results suggest that the lactate-induced Ca2+ increase is not due to the closing of K+ channels, but at least in part, to the suppression of Ca2+ efflux from HIT cells...
  27. ncbi request reprint Altered sensitivity to a novel vasoconstrictor endothelin-1 (1-31) in myometrium and umbilical artery of women with severe preeclampsia
    Y Saijo
    Department of Obstetrics and Gynecology, University of Tokushima, Tokushima, 770 8503, Japan
    Biochem Biophys Res Commun 286:964-7. 2001
    ..The stronger contraction of myometrium by ET-1 (1-31) in patients with severe preeclampsia observed for the first time in the present study suggests that ET-1 (1-31) might be involved in the development of preeclampsia...
  28. ncbi request reprint Ischaemic electrocardiographic changes after massive blood transfusion: findings based on myocardial scintigraphy using 99mTc-MIBI and 123I-MIBG
    Y Kondo
    Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
    Acta Cardiol 53:279-83. 1998
    ..Myocardial scintigraphy using 99mTc-MIBI or 123I-MIBG can be useful for the evaluation of myocardial dysfunction with reversible myocardial infarction...
  29. ncbi request reprint Evaluation of myocardial sympathetic nerve function in patients with mitral valve prolapse using iodine-123-metaiodobenzylguanidine myocardial scintigraphy
    F Kishi
    Department of Digestive and Cardiovascular Medicine, University of Tokushima Graduate School, Tokushima 770 8053, Japan
    J Med 35:187-99. 2004
    ..There was no significant difference in the H/M ratio between MVP patients and the control group. These results indicate that MIBG can be used to evaluate localized myocardial sympathetic nerve function in MVP...
  30. ncbi request reprint A 90-year old patient with atrial septal defect and sinus rhythm
    M Nomura
    Second Department of Internal Medicine, University of Tokushima, Japan
    Acta Cardiol 51:377-80. 1996
    ..Literature searches revealed no similar report of such a case. In addition, this patient represents the oldest documented patients with ASD associated and sinus rhythm...
  31. ncbi request reprint Catecholamine-induced stimulation of growth in Vibrio species
    M Nakano
    Department of Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Lett Appl Microbiol 44:649-53. 2007
    ....
  32. ncbi request reprint Changes in hemodynamics and autonomic nervous activity in patients undergoing laparoscopic cholecystectomy: differences between the pneumoperitoneum and abdominal wall-lifting method
    N Uemura
    Department of Gastroenterology, National Kochi Hospital, Kochi, Japan
    Endoscopy 34:643-50. 2002
    ..Intraoperative changes in circulatory hemodynamics and autonomic nervous activity were evaluated in 33 patients with cholelithiasis who underwent laparoscopic cholecystectomy...
  33. ncbi request reprint K(Ca) channel-opening activity of Ginkgo Biloba extracts and ginsenosides in cultured endothelial cells
    Z Li
    Department of Pharmacology, Hunan Medical University, Changsha, China
    Clin Exp Pharmacol Physiol 28:441-5. 2001
    ..These compounds may regulate nitric oxide release by changing the cell membrane potential in vascular endothelial cells...
  34. ncbi request reprint Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I)
    Y Nakaya
    Biochem Biophys Res Commun 95:1168-72. 1980