Yasuhiro Nakamura

Summary

Affiliation: St. Mary's Hospital
Country: Japan

Publications

  1. ncbi request reprint A variant very low density lipoprotein receptor lacking 84 base pairs of O-linked sugar domain in the human brain myelin
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon machi 422, Kurume, Japan
    Brain Res 793:47-53. 1998
  2. ncbi request reprint D2-40 antibody immunoreactivity in developing human brain, brain tumors and cultured neural cells
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon Machi, Kurume shi, and Department of Pathology and Biodefense, Saga Medical School, Japan
    Mod Pathol 19:974-85. 2006
  3. ncbi request reprint A tetraploid liveborn neonate: cytogenetic and autopsy findings
    Yasuhiro Nakamura
    Department of Clinical Laboratories, St Mary s Hospital, Kurume, Japan
    Arch Pathol Lab Med 127:1612-4. 2003
  4. ncbi request reprint Expression of tubulin beta II in neural stem/progenitor cells and radial fibers during human fetal brain development
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Kurume University School of Medicine, Kurume, Japan
    Lab Invest 83:479-89. 2003
  5. ncbi request reprint Architectural changes in the developing human brain based on the matrix cell theory
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Kurume 830 8543, Japan
    Congenit Anom (Kyoto) 42:167-74. 2002
  6. ncbi request reprint A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, 422, Tsubukuhon Machi, Kurume shi, Japan 830 8543
    J Histochem Cytochem 53:423-30. 2005
  7. ncbi request reprint Significance of the variant and full-length forms of the very low density lipoprotein receptor in brain
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon machi 422, Kurume 830 8543, Japan
    Brain Res 922:209-15. 2001
  8. ncbi request reprint Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Kurume University, Japan
    J Histochem Cytochem 49:439-44. 2001
  9. ncbi request reprint Very low-density lipoprotein receptor in fetal intestine and gastric adenocarcinoma cells
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon Machi, Kurume, Japan
    Arch Pathol Lab Med 124:119-22. 2000
  10. doi request reprint Androgen and androgen-metabolizing enzymes in metastasized lymph nodes of breast cancer
    Yukiko Shibahara
    Department of Pathology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aobaku, Sendai, Miyagi, Japan, 980 8575 Electronic address
    Hum Pathol 44:2338-45. 2013

Collaborators

Detail Information

Publications68

  1. ncbi request reprint A variant very low density lipoprotein receptor lacking 84 base pairs of O-linked sugar domain in the human brain myelin
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon machi 422, Kurume, Japan
    Brain Res 793:47-53. 1998
    ..However, no variant form of VLDLR was found in any tissues of mouse. This variant form of VLDLR should thus be studied in greater detail using human tissues or cells...
  2. ncbi request reprint D2-40 antibody immunoreactivity in developing human brain, brain tumors and cultured neural cells
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon Machi, Kurume shi, and Department of Pathology and Biodefense, Saga Medical School, Japan
    Mod Pathol 19:974-85. 2006
    ..As D2-40 antibody recognizes cell surface antigen M2A, it might be a candidate cell surface marker for isolation of human neural stem cells/neuronal lineage cells in the fluorescence-activated cell sorting technique...
  3. ncbi request reprint A tetraploid liveborn neonate: cytogenetic and autopsy findings
    Yasuhiro Nakamura
    Department of Clinical Laboratories, St Mary s Hospital, Kurume, Japan
    Arch Pathol Lab Med 127:1612-4. 2003
    ..Therefore, it is most likely that the tetraploidy was caused by a cytoplasmic cleavage failure at the first mitotic division...
  4. ncbi request reprint Expression of tubulin beta II in neural stem/progenitor cells and radial fibers during human fetal brain development
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Kurume University School of Medicine, Kurume, Japan
    Lab Invest 83:479-89. 2003
    ..Expression cloning and immunoblot analysis demonstrated the antigen to be tubulin beta II, which would thus be a good marker for studying RFs and neural stem/progenitor cells in the early developing human brain...
  5. ncbi request reprint Architectural changes in the developing human brain based on the matrix cell theory
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, Kurume 830 8543, Japan
    Congenit Anom (Kyoto) 42:167-74. 2002
    ..Particularly, the existence of glial fibrillary acidic protein is re-evaluated in the developing human brain. The commonly used terms and concepts "radial glial fiber" or "subventricular zone" are also re-evaluated...
  6. ncbi request reprint A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum
    Yasuhiro Nakamura
    Department of Pathology, St Mary s Hospital, 422, Tsubukuhon Machi, Kurume shi, Japan 830 8543
    J Histochem Cytochem 53:423-30. 2005
    ..The antigenicity of the KIAA0864 protein was confirmed using human cDNA of the KIAA0864 protein, a protein expression vector, and an HFB-16 antibody...
  7. ncbi request reprint Significance of the variant and full-length forms of the very low density lipoprotein receptor in brain
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon machi 422, Kurume 830 8543, Japan
    Brain Res 922:209-15. 2001
    ..This suggests that the variant VLDLR is important for the developing human brain and the full length VLDLR has modified functions in aged and Alzheimer brains...
  8. ncbi request reprint Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Kurume University, Japan
    J Histochem Cytochem 49:439-44. 2001
    ..In conclusion, there is a possibility of complex formation and functional cooperation of CD9 with HB-EGF and/or integrin alpha3beta1 in several tissues...
  9. ncbi request reprint Very low-density lipoprotein receptor in fetal intestine and gastric adenocarcinoma cells
    Y Nakamura
    Department of Pathology, St Mary s Hospital, Tsubukuhon Machi, Kurume, Japan
    Arch Pathol Lab Med 124:119-22. 2000
    ..This receptor reportedly binds specifically to very low-density lipoproteins; however, its distribution and functions in vivo have yet to be elucidated. We investigated the expression and regulation of VLDLR in fetal and carcinoma cells...
  10. doi request reprint Androgen and androgen-metabolizing enzymes in metastasized lymph nodes of breast cancer
    Yukiko Shibahara
    Department of Pathology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aobaku, Sendai, Miyagi, Japan, 980 8575 Electronic address
    Hum Pathol 44:2338-45. 2013
    ....
  11. doi request reprint Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1
    Yukiko Shibahara
    Department of Pathology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575, Japan
    J Pathol 227:357-66. 2012
    ..Therefore, AIs may exert tumour-suppressing effects upon breast cancer cells by suppressing aromatase gene expression via restoration of let-7f...
  12. ncbi request reprint Nuclear receptor DAX1 in human prostate cancer: a novel independent biological modulator
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Endocr J 56:39-44. 2009
    ..DAX1 immunoreactivity is considered a new biological modulator of human prostate cancer, but independent to the status of sex steroid receptors in human prostate cancer tissues...
  13. doi request reprint Immunohistochemical analysis of aromatase in metastatic lymph nodes of breast cancer
    Yukiko Shibahara
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Pathol Int 63:20-8. 2013
    ..In conclusion, aromatase status in primary tumors generally represents its status in metastatic lymph nodes. This indicates that the endocrine environment of estrogen receptor positive tumors remain stable during the metastatic process...
  14. doi request reprint Cyclin D1 (CCND1) expression is involved in estrogen receptor beta (ERβ) in human prostate cancer
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Prostate 73:590-5. 2013
    ..This interaction is of particular interest as CCND1 has been implicated in the development of prostate cancer...
  15. ncbi request reprint Immunolocalization of liver receptor homologue-1 (LRH-1) in human breast carcinoma: possible regulator of insitu steroidogenesis
    Yasuhiro Miki
    Department of Pathology, Tohoku University, Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Cancer Lett 244:24-33. 2006
    ..These results suggest that LRH-1 is frequently detected in breast carcinoma tissues, and plays important roles including the regulation of in situ steroidogenesis...
  16. ncbi request reprint Progesterone receptor subtypes in vascular smooth muscle cells of human aorta
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Seiryomachi, Sendai, Japan
    Endocr J 52:245-52. 2005
    ..PR-B was equally expressed between male and female aorta, but PR-A was more abundant in female than in male aorta. This finding demonstrated that the status of PR subtype expression was associated with the difference of genders...
  17. pmc MDM2: a novel mineralocorticoid-responsive gene involved in aldosterone-induced human vascular structural remodeling
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Am J Pathol 169:362-71. 2006
    ....
  18. ncbi request reprint Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane
    Yasuhiro Miki
    Department of Pathology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, Miyagi, 980 8575, Japan
    Bone 40:876-87. 2007
    ..These results indicated that the steroidal aromatase inhibitor, EXE, stimulated hFOB cell proliferation via both AR dependent and independent pathways...
  19. doi request reprint Oestrogen-induced genes in ductal carcinoma in situ: their comparison with invasive ductal carcinoma
    Akiko Ebata
    Department of Pathology, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aobaku, Sendai, Japan
    Endocr Relat Cancer 19:485-96. 2012
    ....
  20. ncbi request reprint Expression of tubulin beta II in neuroepithelial tumors: reflection of architectural changes in the developing human brain
    Yasuo Sugita
    Department of Pathology and Biodefense, Saga Medical School, Nabeshima 5 1 1, 849 8501, Saga, Japan
    Acta Neuropathol 110:127-34. 2005
    ....
  21. ncbi request reprint 3beta-Hydroxysteroid dehydrogenase in human aorta
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Seiryo machi, Sendai, Japan
    Endocr J 52:111-5. 2005
    ..These findings all indicated that steroidogenesis via 3beta-HSD may occur in VSMCs of human aorta, possibly related to gender differences and/or the degree of atherosclerosis...
  22. doi request reprint Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor
    Shinya Iida
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Mol Cell Endocrinol 350:99-106. 2012
    ..These results suggest the potential therapeutic efficacy of the combined therapy of mTOR and MEK inhibitors or a dual inhibitor for the treatment of NET patients...
  23. pmc E4F1, a novel estrogen-responsive gene in possible atheroprotection, revealed by microarray analysis
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Aoba ku, Sendai 980 8575, Japan
    Am J Pathol 165:2019-31. 2004
    ..E4F1 is therefore considered one of the estrogen-responsive genes involving ER alpha-mediated inhibition of VSMC proliferation and may play an important role in estrogen-related atheroprotection of human aorta...
  24. doi request reprint Development of the human adrenal zona reticularis: morphometric and immunohistochemical studies from birth to adolescence
    Xiao Gang Hui
    Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Endocrinol 203:241-52. 2009
    ..Results of our present study support the theory of age-dependent adrenocortical cell migration and also indicated that ZR development is not only associated with adrenarche, but may play important roles in an initiation of puberty...
  25. ncbi request reprint Expression of Myc target gene mina53 in subtypes of human lymphoma
    Kwesi Teye
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume 830 0011, Japan
    Oncol Rep 18:841-8. 2007
    ..These results suggest that although Mina53 expression is not prominent in lymphoma in general, it may be related to tumor progression of B cell lymphoma...
  26. ncbi request reprint Immunolocalization of nuclear transcription factors, DAX-1 and Ad4BP/SF-1, in human common epithelial ovarian tumors: correlations with StAR and steroidogenic enzymes in epithelial ovarian carcinoma
    Manar Abd-Elaziz
    Department of Pathology, Tohoku University School of Medicine and Tohoku University Hospital, Sendai, Japan
    Int J Gynecol Pathol 24:153-63. 2005
    ..The status of intratumoral DAX-1, Ad4BP/SF-1, and StAR and steroidogenic enzymes in epithelial cells and intratumoral stromal cells of epithelial ovarian carcinoma may contribute in the progression and/or aggressiveness of these tumors...
  27. doi request reprint Androgenic pathway in triple negative invasive ductal tumors: its correlation with tumor cell proliferation
    Keely M McNamara
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Cancer Sci 104:639-46. 2013
    ..These results suggest that the presence of androgen synthesizing pathways in addition to AR expression in tumor cells could confer a better clinical outcome through suppression of cell proliferation...
  28. doi request reprint Estrogen-related receptor α in normal adrenal cortex and adrenocortical tumors: involvement in development and oncogenesis
    Saulo J A Felizola
    Tohoku University Graduate School of Medicine, Department of Pathology, Sendai, Japan
    Mol Cell Endocrinol 365:207-11. 2013
    ..Therefore, we examined ERRα expression in both normal adrenal cortex (NAC) and adrenocortical tumor (ACT) in order to study the possible correlation of ERRα with adrenal development and tumor development...
  29. doi request reprint Peroxisome proliferator-activated receptor gamma in human prostate carcinoma
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Pathol Int 59:288-93. 2009
    ..036), and serum concentration of prostate-specific antigen (P = 0.0004). In conclusion, PPARgamma immunoreactivity is considered to be a new clinicopathological parameter of human prostate cancer...
  30. doi request reprint Retinoid receptors in human esophageal squamous cell carcinoma: retinoid X receptor as a potent prognostic factor
    Fumiyoshi Fujishima
    Department of Pathology, Tohoku University School of Medicine, Japan
    Pathol Int 61:401-8. 2011
    ..0187). These findings all indicate the important roles of retinoid receptors, especially, RXR in the esophageal squamous cell carcinoma...
  31. ncbi request reprint Somatostatin receptor subtypes in human non-functioning neuroendocrine tumors and effects of somatostatin analogue SOM230 on cell proliferation in cell line NCI-H727
    Katsuhiko Ono
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Anticancer Res 27:2231-9. 2007
    ..Therefore, SOM230 has advantages in controlling the cell proliferation of these tumors but the status of sstr subtypes should be determined, possibly using immunohistochemistry, in order to confer its maximum benefits...
  32. ncbi request reprint Immunohistochemical distribution of tubulin beta II in human normal and neoplastic tissues
    Eriko Oda
    Department of Chemistry, Kurume University School of Medicine, Kurume 830 0011, Japan
    Kurume Med J 52:117-25. 2005
    ....
  33. doi request reprint Human adrenal cells that express both 3β-hydroxysteroid dehydrogenase type 2 (HSD3B2) and cytochrome b5 (CYB5A) contribute to adrenal androstenedione production
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Steroid Biochem Mol Biol 123:122-6. 2011
    ....
  34. ncbi request reprint Estrogen actions and in situ synthesis in human vascular smooth muscle cells and their correlation with atherosclerosis
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Steroid Biochem Mol Biol 93:263-8. 2005
    ..They indicate that both abundance of these estrogen-metabolizing enzymes in female aorta and relative levels of ER in VSMCs of female neointima may be associated with the status of atherosclerotic changes...
  35. ncbi request reprint Steroid sulfatase and estrogen sulfotransferase in human prostate cancer
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Prostate 66:1005-12. 2006
    ..Estrogen sulfotransferase (EST) and steroid sulfatase (STS) are known to be involved in in situ estrogen production in estrogen dependent human cancer such as breast cancer, but unknown in prostate cancer...
  36. doi request reprint Glutamate receptors and the regulation of steroidogenesis in the human adrenal gland: the metabotropic pathway
    Saulo J A Felizola
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Mol Cell Endocrinol 382:170-7. 2014
    ..However, details regarding the expression levels and functions of these receptors in human adrenocortical tissues remain unknown...
  37. doi request reprint Case reports of primary pulmonary adenocarcinoma with pleural spread: so-called pseudomesotheliomatous adenocarcinoma
    Ryoko Saito
    Department of Pathology, Tohoku University School of Medicine, Miyagi, Japan
    Pathol Int 62:709-15. 2012
    ..Additionally, we performed quantitative analysis of asbestos bodies in pseudomesotheliomatous adenocarcinoma...
  38. ncbi request reprint Sex steroid-producing enzymes in human breast cancer
    Takashi Suzuki
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Endocr Relat Cancer 12:701-20. 2005
    ....
  39. ncbi request reprint A case of prostatic adenocarcinoma with Paneth cell-like appearance
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Pol J Pathol 62:60-4. 2011
    ..Paneth cell-like appearance of prostatic carcinoma cells should be recognized and considered as a sign of neuroendocrine differentiation due to the possible association with resistance to hormone therapy...
  40. ncbi request reprint A case of cutaneous bronchogenic cyst in the scapular area
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Pol J Pathol 62:120-1. 2011
    ..Histopathological examination of this tumour revealed a subcutaneous cystic legion formed by ciliated columnar epithelium with smooth muscle bundles and squamous epithelium with sebaceous glands...
  41. doi request reprint Expression of KIAA 0864 protein in neuroepithelial tumors: an analysis based on the presence of monoclonal antibody HFB-16
    Yasuo Sugita
    Department of Pathology, Kurume University School of Medicine, Asahimachi 67, Kurume, Fukuoka, 830 0011, Japan
    J Neurooncol 89:151-8. 2008
    ..In addition, it could be a useful tool for performing the differential diagnosis between GBs and CNS supratentorial PNET...
  42. ncbi request reprint Transcription factor GATA-6 in the human adrenocortex: association with adrenal development and aging
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Endocr J 54:783-9. 2007
    ....
  43. pmc Increased expression of a Myc target gene Mina53 in human colon cancer
    Kwesi Teye
    Department of Forensic Medicine, Kurume University School of Medicine, Kurume, Japan
    Am J Pathol 164:205-16. 2004
    ..Together, our results indicate that the elevated expression of Mina53 is a characteristic feature in colon cancer, one that may have therapeutic applications...
  44. ncbi request reprint Immunohistochemical distribution of CD9 in parotid gland tumors
    Kikuo Sakamoto
    Department of Otolaryngology, Head and Neck Surgery, Kurume University School of Medicine, Asahi machi 67, Kurume shi 830 0011, Japan
    Auris Nasus Larynx 31:49-55. 2004
    ..CD9 is a member of the tetra-membrane-spanning glycoprotein family called tetraspanin. CD9 suppresses breeding and motion in some types of cancer cells. At present, the expression of CD9 in the salivary gland has not yet been elucidated...
  45. ncbi request reprint In situ androgen production in human gastric carcinoma--androgen synthesizing and metabolizing enzymes
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Anticancer Res 26:1935-9. 2006
    ..5Alpha-reductase (5alpha-reductase) types 1 and 2 and 17beta-hydroxysteroid dehydrogenase type 5 (17beta-HSD type 5) are considered important local regulators of androgen production in human androgen-responsive tissues and cancer...
  46. ncbi request reprint Rapid quantitative analysis of human cytomegalovirus DNA by the real-time polymerase chain reaction method
    Sanae Numata
    First Department of Pathology, Kurume University School of Medicine, Kurume shi, Fukuoka, Japan
    Arch Pathol Lab Med 129:200-4. 2005
    ..Therefore, early and accurate treatment based on rapid and certain detection is needed to prevent fatal CMV infection diseases...
  47. ncbi request reprint [A case of medullomyoblastoma]
    Yukari Aramaki
    Department of Neurosurgery, St Mary s Hospital, Our Lady of the Snow Social Medical Corporation, Kurume City, Fukuoka, Japan
    No Shinkei Geka 39:1073-7. 2011
    ..Immunohistochemical studies confirmed the presence of both a primitive neuroectodermal component and rhabdomyoblastic differentiation, consistent with the diagnosis of medullomyoblastoma...
  48. ncbi request reprint A case of villous adenoma of the urinary bladder with tubulovillous architecture: characterization by immunohistochemical analysis
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Pol J Pathol 62:179-82. 2011
    ..Transurethral resection was performed and histopathological examination revealed predominantly tubulovillous architecture, and showed an identical immunohistochemical profile to villous adenoma associated with cystitis glandularis...
  49. ncbi request reprint Autopsy case of disseminated Trichosporon inkin infection identified with molecular biological and biochemical methods
    Takahiro Koyanagi
    Department of Pathology, St Mary s Hospital, Kurume, Japan
    Pathol Int 56:738-43. 2006
    ..It is difficult to make a diagnosis of Trichosporon infection on only histological examination; therefore, molecular biological and biochemical methods are needed in a diagnosis of disseminated trichosporonosis...
  50. doi request reprint Malignant melanoma arising in a plaque-type blue nevus
    Sakiko Sanada
    Department of Pathology, Kurume University School of Medicine, St Mary s Hospital, Kurume, Japan
    Pathol Int 62:749-53. 2012
    ..We also discuss the histological features and clinical course in our patient in context with previous related literature...
  51. ncbi request reprint Estrogen receptors in atherosclerotic human aorta: inhibition of human vascular smooth muscle cell proliferation by estrogens
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Mol Cell Endocrinol 219:17-26. 2004
    ..Our study also indicates that decreased levels of ER, especially ERalpha, in the female atherosclerotic neointima may be associated with progression of atherosclerotic changes...
  52. ncbi request reprint Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy
    Yasuhiro Nakamura
    Department of Pathology, Tohoku Graduate University School of Medicine, 2 1 Seiryo machi, Sendai 980 8575, Japan
    Int J Clin Oncol 10:348-52. 2005
    ..Clinically, the primary tumor and lymph node metastases were markedly reduced. Subsequently the patient underwent curative surgery and was alive without recurrence for more than 3 years after the surgery...
  53. pmc Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta
    Yasuhiro Nakamura
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Am J Pathol 163:1329-39. 2003
    ....
  54. ncbi request reprint Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes
    Xuezhu Xu
    Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    J Invest Dermatol 123:1120-6. 2004
    ..Furthermore, we demonstrated that forced expression of YY1 in differentiated keratinocytes results in specific downregulation of expression of other early and late differentiation markers...
  55. ncbi request reprint Expression of the Neural RNA-binding protein Musashi1 in pediatric brain tumors
    Aya Nakano
    Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan
    Pediatr Neurosurg 43:279-84. 2007
    ..This test could be easily applied to routine clinical diagnosis...
  56. doi request reprint Paraneoplastic dermatomyositis triggered and exacerbated by oral 5-fluorouracil administration
    Yasuhiro Kawachi
    Eur J Dermatol 18:195-6. 2008
  57. ncbi request reprint Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis
    Ayako Hirota
    Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    J Invest Dermatol 124:825-32. 2005
    ..These findings thus demonstrate that the Nrf2-Keap1 pathway plays an important role in the protection of the skin against UVA irradiation...
  58. ncbi request reprint Transmitral inflow pattern assessed by Doppler echocardiography in angiotensin II type 1A receptor knockout mice with myocardial infarction
    Yasuhiro Nakamura
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Circ J 66:192-6. 2002
    ..05). mRNA expressions of ANP, BNP, collagen I and collagen III in the non-infarcted LV and RV of KO-MI were significantly lower than WT-MI. In conclusion, transmitral inflow abnormalities in KO-MI were attenuated compared with WT-MI...
  59. ncbi request reprint The role of the sca-1+/CD31- cardiac progenitor cell population in postinfarction left ventricular remodeling
    Xiaohong Wang
    Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, 55455, USA
    Stem Cells 24:1779-88. 2006
    ..Sca-1(+)/CD31(-) cells may hold therapeutic possibilities with regard to the treatment of ischemic heart disease...
  60. ncbi request reprint Nipradilol can prevent left ventricular systolic and diastolic dysfunction after myocardial infarction in rats
    Satoru Izutani
    Department of Internal Medicine, Graduate School of Medicine, Osaka City University, Japan
    Circ J 66:289-93. 2002
    ..In conclusions, nipradilol prevents the cardiac remodeling that is accompanied by systolic and diastolic dysfunction, and inhibits abnormal myocardial gene expression after MI...
  61. ncbi request reprint S-1, an oral fluoropyrimidine, enhances radiation response of DLD-1/FU human colon cancer xenografts resistant to 5-FU
    Eiko Nakata
    Tohoku University Biomedical Engineering Research Organaization, Miyagi 980 8575, Japan
    Oncol Rep 16:465-71. 2006
    ..06). The effect could be attributed to the ability of S-1 to increase cell radiosensitivity (EF = 1.9) and to the down-regulation of TS involved in cellular processes leading to radio- and (or) chemo-resistance...
  62. ncbi request reprint In situ androgen producing enzymes in human prostate cancer
    Yasuhiro Nakamura
    Departments of Pathology, Tohoku University School of Medicine, Seiryo machi, Sendai, Japan
    Endocr Relat Cancer 12:101-7. 2005
    ....
  63. ncbi request reprint Xenotransplantation of long-term-cultured swine bone marrow-derived mesenchymal stem cells
    Yasuhiro Nakamura
    Cardiovascular Division, Department of Medicine, University of Minnesota Academic Health Center, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Stem Cells 25:612-20. 2007
    ....
  64. ncbi request reprint The combination of ubiquitous transcription factors AP-1 and Sp1 directs keratinocyte-specific and differentiation-specific gene expression in vitro
    Yasuhiro Nakamura
    Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Exp Dermatol 16:143-50. 2007
    ..Our findings also provide a simple model of the mechanisms underlying regulation of cell type-specific and cell differentiation-specific gene expression by ubiquitously expressed transcription factors...
  65. ncbi request reprint Multipotent adult progenitor cell transplantation increases vascularity and improves left ventricular function after myocardial infarction
    Beatriz Pelacho
    Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Tissue Eng Regen Med 1:51-9. 2007
    ....
  66. ncbi request reprint Metastin stimulates aldosterone synthesis in human adrenal cells
    Yasuhiro Nakamura
    Department of Physiology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Reprod Sci 14:836-45. 2007
    ..These results suggest that the high fetal/maternal levels of metastin seen during pregnancy may affect adrenal production of aldosterone...
  67. doi request reprint Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice
    Yasuhiro Kawachi
    Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    J Invest Dermatol 128:1773-9. 2008
    ..Journal of Investigative Dermatology (2008) 128, 1773-1779; doi:10.1038/sj.jid.5701245; published online 17 January 2008...
  68. ncbi request reprint Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction
    Ryo Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Arterioscler Thromb Vasc Biol 25:1168-73. 2005
    ..We hypothesized that transplantation of VEGF-expressing MSCs could effectively treat acute myocardial infarction (MI) by providing enhanced cardioprotection, followed by angiogenic effects in salvaging ischemic myocardium...