Research Topics
Genomes and Genes | M ItoSummaryAffiliation: St. Marianna University School of Medicine Country: Japan Publications
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Publications
T cells and mast cells as a major source of interleukin-13 in atopic dermatitisWataru Obara
Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan
Dermatology 205:11-7. 2002..Recent studies suggest that cytokines expressed locally in the skin play several critical roles in atopic dermatitis (AD), however, little is known about the role of IL-13 in AD lesions...- Establishment and characterization of a mouse neural crest derived cell line (NCCmelan5)S Ooka
Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan
Pigment Cell Res 14:268-74. 2001..It is clear that our attempt to establish immortal cell lines from murine neural crest cells would have never been successful without the addition of SCF and EDN3, since C57NCC SE and NCCmelan5 cells require those factors to proliferate... - Expression of cutaneous fatty acid-binding protein and its mRNA in rat skinR Watanabe
Department of Dermatology, Niigata University School of Medicine, Japan
Arch Dermatol Res 288:481-3. 1996..Since epidermis and sebaceous glands are active sites of fatty acid synthesis, these results suggest that C-FABP may have important roles in the transport and synthesis of fatty acids... - High transepidermal water loss induces fatty acid synthesis and cutaneous fatty acid-binding protein expression in rat skinH Yamaguchi
Department of Dermatology, Niigata University School of Medicine, Japan
J Dermatol Sci 17:205-13. 1998..These results suggest that increase of TEWL itself stimulates C-FABP expression, leading to activation of fatty acid metabolism... - mu-Crystallin, thyroid hormone-binding protein, is expressed abundantly in the murine inner root sheath cellsN Aoki
Department of Dermatology, Niigata University School of Medicine, Niigata, Japan
J Invest Dermatol 115:402-5. 2000..These results suggest the possible involvement of mu-crystallin in the development of mouse hair follicles during the anagen phase... - Stem cell factor and/or endothelin-3 dependent immortal melanoblast and melanocyte populations derived from mouse neural crest cellsY Kawa
Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan
Pigment Cell Res 13:73-80. 2000..This suggests that NCC-S4.1 cells are melanoblasts that have the potential to differentiate into melanocytes. These cell populations will be extremely useful to study factors that affect melanocyte development and melanogenesis... - Hair follicle has a novel anagen-specific protein, mKAP13N Aoki
Department of Dermatology, Niigata University School of Medicine, Japan
J Invest Dermatol 111:804-9. 1998..Therefore, we have termed this novel protein mKAP13 according to the unified nomenclature... - A novel mouse gene, Sh3yl1, is expressed in the anagen hair follicleN Aoki
Department of Dermatology, Niigata University School of Medicine, Niigata, Japan
J Invest Dermatol 114:1050-6. 2000..Thus, these data suggest the possible involvement of Sh3yl1 in the development of hair follicles during the anagen phase... - Application of confocal laser scanning microscopy to differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisitaT Kazama
Department of Dermatology, Niigata University School of Medicine, Japan
Br J Dermatol 138:593-601. 1998..These spatial relationships are compatible with their previously described ultrastructural locations. Thus, this method appears to be useful in the differential diagnosis of BP and EBA... - A novel type II cytokeratin, mK6irs, is expressed in the Huxley and Henle layers of the mouse inner root sheathN Aoki
Department of Dermatology, Niigata University School of Medicine, Asahimachi Dori, Niigata, Japan
J Invest Dermatol 116:359-65. 2001.... - Atrichia with papular lesions: electron microscopic observations of cystic lesionsK Nomura
Department of Dermatology, Aomori Prefectural Central Hospital, Higashi Tsukurimichi 2 1 1, Aomori 030 0913, Japan
Am J Dermatopathol 23:227-31. 2001..In particular, the structure of the cyst wall corresponded well to infundibular and/or isthmal portions of the outer root sheath of the hair follicle... - Cell kinetic study of human and mouse hair tissues using anti-bromodeoxyuridine monoclonal antibodyM Tezuka
Department of Dermatology, Niigata University School of Medicine, Japan
J Dermatol Sci 1:335-46. 1990..The sequential cessation of mitotic activity of these cells is associated with the morphological changes from anagen through catagen to telogen. These findings were common to both human and mouse hair tissues... - Netherton syndrome in two Japanese siblings with a novel mutation in the SPINK5 gene: immunohistochemical studies of LEKTI and other epidermal moleculesY Shimomura
Department of Dermatology, Niigata University School of Medicine, Asahimachi Dori, Niigata 951 8510, Japan
Br J Dermatol 153:1026-30. 2005..Previous studies have clearly shown a crucial role for LEKTI in skin barrier formation... - Fatty acid composition of sebum wax esters and urinary androgen level in normal human individualsA Yamamoto
Department of Dermatology, Niigata University School of Medicine, Japan
J Dermatol Sci 1:269-76. 1990..This result suggests that the synthesis of iso or anteiso fatty acids may be controlled by complex factors and that there may be a unique source of anteiso fatty acids in human sebaceous glands... 
Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in miceM Ito
Central Institute for Experimental Animals, Kawasaki, Japan
Antimicrob Agents Chemother 44:2259-62. 2000..carinii-associated pneumonia. These results suggest that FK463 is potentially useful as a prophylactic agent against P. carinii infection...- Histologic study of the regeneration process of human hair follicles grafted onto SCID mice after bulb amputationT Hashimoto
Department of Dermatology, Niigata University School of Medicine, Japan
J Investig Dermatol Symp Proc 6:38-42. 2001.... - Immunohistochemical distribution of cutaneous fatty acid-binding protein in human skinR Watanabe
Department of Dermatology, Niigata University School of Medicine, Japan
J Dermatol Sci 16:17-22. 1997..Moreover, it is suggested that C-FABP has important roles in the transport and metabolism of fatty acids in epidermis and that altered lipid metabolism may affect the proliferation and/or differentiation of keratinocyte... - Male New Zealand Black/KN mice: a novel model for autoimmune-induced permanent alopecia?A Hiroi
Department of Dermatology, Wakayama Medical University, Kimiidera 811 1, Wakayama, Japan
Br J Dermatol 155:437-45. 2006..During the course of our studies in a well-established mouse model for chronic rheumatoid arthritis, the New Zealand Black/KN (NZB/KN) mouse, we noticed that ageing male NZB/KN mice developed spontaneous APA... - A case of recessive dystrophic epidermolysis bullosa caused by compound heterozygous mutations in the COL7A1 geneS Suzuki
Department of Dermatology, Niigata University School of Medicine, Asahimachi-dori, Niigata 951-8510, Japan
Br J Dermatol 155:838-40. 2006 - A successfully treated case of mycetoma due to Nocardia veteranaM Kashima
Department of Dermatology, St Marianna University, Kawasaki, Kanagawa 216 8511, Japan
Br J Dermatol 152:1349-52. 2005..This is the first case report of mycetoma due to N. veterana in a clinical setting... 
Primary cutaneous CD30+ anaplastic large-cell lymphoma with generalized skin involvement and involvement of one peripheral lymph node, successfully treated with low-dose oral etoposideN Yamane
Department of Dermatology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan
Clin Exp Dermatol 34:e56-9. 2009..We reviewed the previously reported cases of PCALCL treated with low-dose etoposide. We suggest that oral etoposide might be a useful effective treatment for treatment of relapsed multifocal PCALCL...- Immunoblotting detection of gamma-catenin (plakoglobin) antibody in the serum of a patient with paraneoplastic pemphigusM Ishii
Department of Dermatology, Niigata University School of Medicine, Asahimachi-dori 1, Niigata 951-8510, Japan
Br J Dermatol 144:377-9. 2001..Immunoblot study using affinity-purified gamma-catenin protein revealed that his serum recognized gamma-catenin (plakoglobin) in epidermal, thymic tumour and mouse bladder extracts... - Isolation and characterization of mouse high-glycine/tyrosine proteinsN Aoki
Department of Dermatology, Niigata University School of Medicine, Niigata, Japan
J Biol Chem 272:30512-8. 1997..The novel findings that each gene is activated transcriptionally with a distinct expression pattern spatially and temporally suggest that there is a remarkable difference in the distribution of these proteins in hair... - Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patientsM Koyama
Institute for Digestive Disease, Second Hospital, Nippon Medical School, 1 396, Kosugi cho, Nakahara ku, Kawasaki, Japan
Mutat Res 406:71-7. 1999..G. Knudson, Hereditary cancer, oncogenes, and anti-oncogenes, Cancer Res. 45 (1985) 1437-1443.]... - A case of febrile ulceronecrotic Mucha-Habermann disease requiring debridement of necrotic skin and epidermal autograftK Yanaba
Department of Dermatology, The Jikei University School of Medicine, 25 8 Nishishimbashi 3 chome, Minato ku, Tokyo 105 8461, Japan
Br J Dermatol 147:1249-53. 2002..Debridement of the necrotic skin and skin grafting using cultured epidermal autografts and meshed allografts of cadaver skin led to prompt reepithelization... - Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinomaH Mineta
Department of Otolaryngology, Hamamatsu University School of Medicine, 1 20 1 Handayama, 431 3192 Hamamatsu, Japan
Oral Oncol 39:56-63. 2003..FHIT alteration may play an important role in cancer development of HNSCC, however it did not contribute to the prognosis... - Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha?M Shibasaki
Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan
Diabetologia 45:518-26. 2002..This study addresses this hypothesis and describes a unique method to clarify whether the functional differences between visceral and subcutaneous adipocytes depend on their anatomical location... - Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritisM Ito
Department of Medicine and Molecular Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan
Aliment Pharmacol Ther 16:1449-56. 2002..To investigate the effect of the eradication of Helicobacter pylori on histological gastritis... - Helicobacter pylori-associated gastritis is related to babA2 expression without heterogeneity of the 3' region of the cagA genotype in gastric biopsy specimensX F Xie
Department of Medicine and Molecular Science, Hiroshima University, Hiroshima, Japan
Pathobiology 74:309-16. 2007..Blood group antigen binding adhesin (BabA) helps the strains adhere to the epithelial cell layer and is the most important adhesin of H. pylori... - A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse developmentM Nakashima
Department of Clinical Oral Molecular Biology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812 8582, Japan
Mech Dev 119:21-34. 2002.... - UDP-Gal: betaGlcNAc beta1, 3-galactosyltransferase, polypeptide 3 (GALT3) is a tumour antigen recognised by HLA-A2-restricted cytotoxic T lymphocytes from patients with brain tumourN Tsuda
Department of Immunology, Kurume University School of Medicine, 67 Asohi machi, Kurume, Fukuoka 830 0011, Japan
Br J Cancer 87:1006-12. 2002..These peptides may be useful in the peptide-based specific immunotherapy for patients with malignant brain tumours... - Fatal buckwheat dependent exercised-induced anaphylaxisT Noma
Department of Pediatrics, Kitasato University School of Medicine, Kanagawa, Japan
Asian Pac J Allergy Immunol 19:283-6. 2001..A first case of fatal FEA by buckwheat is reported with reference to specific IgE... - The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritisT Kamada
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan
Aliment Pharmacol Ther 18:245-52. 2003..To investigate whether curing Helicobacter pylori infection improves symptoms over the long-term in Japanese patients with nonulcer dyspepsia and fundic atrophic gastritis... - Preventive effects of sequential treatment with alendronate and 1 alpha-hydroxyvitamin D3 on bone mass and strength in ovariectomized ratsM Ito
Pharmacological Research Department, Teijin Institute for Bio-Medical Research, Teijin Ltd, 4-3-2 Asahigaoka, Hino, 191-8512 Tokyo, Japan
Bone 33:90-9. 2003..Therefore, we propose that 1alpha(OH)D3 may be a good choice to replace alendronate when alendronate treatment cannot be continued for some reason... - Disruption of imprinting in cloned mouse fetuses from embryonic stem cellsH Ogawa
Department of Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan
Reproduction 126:549-57. 2003..These results show that inappropriate reprogramming in some imprinted genes affects the development of cloned embryos, and that aberrant P0 Igf2 transcription in particular may cause the overgrowth of cloned fetuses and placentae... - Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytesL A O'Reilly
The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
Cell Death Differ 11:724-36. 2004..Interestingly, mitogenic stimulation, but not Fas ligation, induced a unique post-translational modification of FADD. These different modifications may determine whether FADD and caspase-8 induce cell death or proliferation... - T cell-dependent elimination of dividing Trypanosoma grosi from the bloodstream of Mongolian jirdsH Sato
Department of Parasitology, Hirosaki University School of Medicine, Hirosaki 036 8562, Japan
Parasitology 128:295-304. 2004..Our findings indicate that T cells play a major role at least in the 'first crisis' during elimination of dividing T. grosi from the bloodstream... - Expression of the ets-1 proto-oncogene in human breast carcinoma: differential expression with histological grading and growth patternS Katayama
Department of Molecular Pathology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8523, Japan
Histol Histopathol 20:119-26. 2005.... - Dicoumarol potentiates cisplatin-induced apoptosis mediated by c-Jun N-terminal kinase in p53 wild-type urogenital cancer cell linesJ Watanabe
Department of Urology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan
Oncogene 25:2500-8. 2006..These results suggested that dicoumarol could enhance cytotoxicity of CDDP in urogenital cancer cells with wild-type p53 through the p53/p21/JNK pathways... - Aberrantly differentiated cells in benign pilomatrixoma reflect the normal hair follicle: immunohistochemical analysis of Ca-binding S100A2, S100A3 and S100A6 proteinsK Kizawa
Basic Research Laboratory, Kanebo Cosmetics Inc, Kotobuki-cho, Odawara, Japan
Br J Dermatol 152:314-20. 2005..Our results show that pilomatrixomas retain a certain degree of differentiation indicative of distinct hair-forming cells... - Detection of rabies virus RNA isolated from several species of animals in Brazil by RT-PCRM Ito
Department of Preventive Veterinary Medicine and Animal Health, Nihon University School of Veterinary Medicine, Fujisawa, Kanagawa, Japan
J Vet Med Sci 63:1309-13. 2001..These results suggest that Brazilian rabies virus isolates could be principally divided into two populations according to genetic difference... - [Seizure and developmental prognosis of West syndrome--combination therapy with high-dose vitamin B6, valproate and low-dose ACTH]T Miyajima
Department of Pediatrics, Shiga Medical Center for Children, Moriyama, Shiga
No To Hattatsu 33:498-504. 2001..In this study, the rate of evolution into intractable epilepsy was low, but long-term mental development was poor. Seizure control by itself seemed to be insufficient to improve long developmental prognosis of West syndrome... - Isolation and RNA gel blot analysis of genes that could serve as potential molecular markers for leaf senescence in Arabidopsis thalianaS Yoshida
Department of Biological Sciences, Graduated School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033 Japan
Plant Cell Physiol 42:170-8. 2001..These expression characteristics of YLS genes will be useful as potential molecular markers, which will enhance our understanding of natural and artificial senescence processes... - c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphomaT Hiyama
First Department of Internal Medicine, Hiroshima University School of Medicine, Minami Ku, Hiroshima 734 8551, Japan
Oncol Rep 8:289-92. 2001..These data suggest that mutation of the c-myc gene may not be commonly associated with development of gastric MALT lymphoma and DLL, and may not be associated with regression of low-grade MALT lymphoma after H. pylori eradication... - Urocortin and corticotropin-releasing factor receptor expression in the human colonic mucosaY Muramatsu
Department of Pathology, Tohoku University School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
Peptides 21:1799-809. 2000..The appearance of urocortin after birth indicates that the exposure to dietary intake and/or luminal bacteria after birth may contribute to the initiation of urocortin expression in human gastrointestinal tract mucosa... - T-cell-specific expression of kinase-defective Eph-family receptor protein, EphB6 in normal as well as transformed hematopoietic cellsM Shimoyama
Department of Medicine, Kobe University School of Medicine, Japan
Growth Factors 18:63-78. 2000..Among T-cell-derived leukemia cells, the expression level of EphB6 seemed to decrease with maturation of the cells. These results suggest that EphB6 expression is regulated in T-cell development... - Human T cell L-plastin bundles actin filaments in a calcium-dependent mannerY Namba
Department of Cell Biology, Kyoto University
J Biochem 112:503-7. 1992..Under suitable conditions, approximately one molecule of L-plastin bound to 8 molecules of actin monomer in the actin filament... - Gene expression during osteoclast-like cell formation induced by antifusion regulatory protein-1/CD98/4F2 monoclonal antibodies (MAbs): c-src is selectively induced by anti-FRP-1 MAbY Higuchi
Department of Microbiology, Mie University School of Medicine, Tsu Shi, Mie Prefecture, Japan
Bone 25:17-24. 1999..On the other hand, no receptor activator of NF-KB ligand (RANKL) mRNA was detectable in any of the samples, suggesting that anti-FRP-1 mAb can induce osteoclast-like cells from blood monocytes without RANKL... - AT2 receptor and vascular smooth muscle cell differentiation in vascular developmentH Yamada
Cardiovascular Research, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Hypertension 33:1414-9. 1999..Taken together, our results suggest that the AT2 receptor promotes vascular differentiation and contributes to vasculogenesis... - Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin IIM I Oliverio
Duke University and Durham Veterans Affairs Medical Centers, Durham, NC 27705, USA
Proc Natl Acad Sci U S A 95:15496-501. 1998..These studies reaffirm and extend the importance of AT1 receptors to mediate physiological functions of the renin-angiotensin system... - Molecular cloning of a cDNA encoding a novel fatty acid-binding protein from rat skinR Watanabe
Department of Biochemistry, Niigata University School of Medicine, Japan
Biochem Biophys Res Commun 200:253-9. 1994..1 kDa and exhibits around 50% identity to myelin P2 protein, adipocyte FABP and heart FABP. Our results propose that C-FABP is a new member of the FABP family... - Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifoliaT Maruyama
Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo, Japan
Biol Pharm Bull 24:373-7. 2001..Here, we report on the cloning of dLMS, and the putative stereochemical regulation mechanism is discussed based on the comparison of the deduced amino acid sequence of dLMS with those of known l-limonene synthases... - Lack of B cell leakiness in BALB/cA-nu, scid double mutant miceK Hioki
Central Institute for Experimental Animals, 1430 Nogawa, Kawasaki 216, Japan
Exp Anim 50:67-72. 2001..BALB/cA-nu, scid mice may be useful as a recipient in allo- and xeno-transplantation experiments because of the absence of both thymic lymphomas and leakiness, in addition to lack of hair... - Overexpression of AML1 transcription factor drives thymocytes into the CD8 single-positive lineageK Hayashi
Department of Molecular Immunology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
J Immunol 167:4957-65. 2001..Thus, overexpression of AML1 is able to skew class II-restricted thymocytes into the CD8 SP lineage, but not to drive the maturation of resulting selected CD8 SP cells... - Molecular cloning, functional expression and characterization of (E)-beta farnesene synthase from Citrus junosT Maruyama
Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan
Biol Pharm Bull 24:1171-5. 2001..A possible reaction mechanism for terpene biosynthesis is also discussed on the basis of sequence comparison of CJFS with known sesquiterpene synthase genes... - Expression of human beta-defensin 2 (hBD-2) in Helicobacter pylori induced gastritis: antibacterial effect of hBD-2 against Helicobacter pyloriY Hamanaka
Department of Molecular Pathology, Nagasaki University School of Medicine, Nagasaki, Japan
Gut 49:481-7. 2001..CONCLUSIONS: H pylori infection induces hBD-2 expression in the human gastric epithelium. hBD-2 inhibited the growth of H pylori in vitro, suggesting that hBD-2 plays an antibacterial role in H pylori induced gastritis... - Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activationT Nii
Department of Clinical Nutrition, School of Medicine, Tokushima University, Kuramoto Cho 3, Tokushima City 770 8503, Japan
Biochem J 358:693-704. 2001..These findings indicated that a removal of the block to mRNA elongation stimulates the induction of system-L amino acid transporter gene transcripts (LAT1 and 4F2hc) in activated T-cells... - A novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSFA Muto
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Leukemia 15:1176-84. 2001..In conclusion, a combination of As2O3 and GM-CSF appears to be a novel differentiation-inducing therapy in patients with APL, including relapsed or RA-resistant cases... - Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID miceY Miura
Department of Virology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan
J Exp Med 193:651-60. 2001..These results suggest that a large number of HIV-1-uninfected CD4+ T cells undergo TRAIL-mediated apoptosis in HIV-infected lymphoid organs... - Sertoli cell-specific rescue of fertility, but not testicular pathology, in Dax1 (Ahch)-deficient male miceB Jeffs
Division of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA
Endocrinology 142:2481-8. 2001..However, the failure to completely rescue the testicular pathology of Dax1-deficient mice suggests that Dax1 expression in other somatic cells is essential for normal testicular development... - Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instabilityT Hiyama
First Department of Internal Medicine, Hiroshima University School of Medicine, Hiroshima 734-8551, Japan
Int J Oncol 18:1207-12. 2001..The treatment may be efficacious as a first-line therapy for patients with high-grade MALT lymphoma. However, our sample size was limited and further studies are needed to clarify the issue... - Expansion of cytolytic CD8(+) natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon gamma productionJ Baker
Department of Medicine, Division of Bone Marrow Transplantation, Stanford University Medical Center, Stanford, CA, USA
Blood 97:2923-31. 2001..These data indicate that CD8(+) NKT cells expanded in this fashion could be useful for preserving graft-versus-leukemia activity without causing GVHD... - Interleukin-4 gene expression and IgE responsivenessH Okudaira
Department of Medicine and Physical Therapy, Faculty of Medicine, University of Tokyo, Japan
Int Arch Allergy Appl Immunol 94:184-6. 1991..The results obtained in the present study may indicate that high and low IgE responder traits are determined depending on their levels of IL-4 mRNA expression...