Affiliation: Sojo University
Ichihara H, Motomura M, Matsumoto Y. Therapeutic effects and anti-metastasis effects of cationic liposomes against pancreatic cancer metastasis in vitro and in vivo. Biochem Biophys Res Commun. 2019;: pubmed publisher
..Overall, the results of this study revealed for the first time, the therapeutic effects and anti-metastasis activity of CL in xenograft mouse models for peritoneal metastasis of human pancreatic cancer. ..
Ichihara H, Nakagawa S, Matsuoka Y, Yoshida K, Matsumoto Y, Ueoka R. Nanotherapy with hybrid liposomes for colorectal cancer along with apoptosis in vitro and in vivo. Anticancer Res. 2014;34:4701-8 pubmed
..Therapeutic effects of HL-25 without any drugs on the liver metastasis of human colorectal cancer were obtained for the first time in vivo. ..
Ichihara H, Yamasaki S, Hino M, Ueoka R, Matsumoto Y. Therapeutic effects of hybrid liposomes with downregulation of inflammatory cytokine for model mice of rheumatoid arthritis in vivo. Bioorg Med Chem Lett. 2015;25:2686-9 pubmed publisher
..Remarkably high therapeutic effects without joint swelling were obtained in CIA mouse models treated with HL-23. ..
Matsumoto Y, Kuwabara K, Ichihara H, Kuwano M. Therapeutic effects of trehalose liposomes against lymphoblastic leukemia leading to apoptosis in vitro and in vivo. Bioorg Med Chem Lett. 2016;26:301-305 pubmed publisher
..The clustering of lipid rafts in plasma membranes of MOLT-4 cells was observed after the treatment with DMTre. Therapeutic effects of DMTre were obtained for xenograft mice model of carcinoma in vivo. ..
Ichihara H, Okumura M, Matsumoto Y. Therapeutic Effects of Hybrid Liposomes Against Xenograft Mouse Model of Colorectal Cancer In Vivo Due to Long-term Accumulation. Anticancer Res. 2016;36:5875-5882 pubmed
..Therapeutic effects of HL without any drugs in the murine xenograft model after subcutaneous inoculation of human colorectal cancer were revealed for the first time in vivo due to long-term accumulation. ..
Motomura M, Ichihara H, Matsumoto Y. Nano-chemotherapy using cationic liposome that strategically targets the cell membrane potential of pancreatic cancer cells with negative charge. Bioorg Med Chem Lett. 2018;28:1161-1165 pubmed publisher
..CL induced apoptosis in BxPC-3 cells via activation of caspase-3, -8, and -9 and mitochondrial events and inhibited tumor enlargement in xenograft mouse models of pancreatic cancer. ..
Ichihara H, Kuwabara K, Matsumoto Y. Trehalose Liposomes Suppress the Growth of Tumors on Human Lung Carcinoma-bearing Mice by Induction of Apoptosis In Vivo. Anticancer Res. 2017;37:6133-6139 pubmed
..Here, we aimed to investigate suppressive effects of DMTreC14 on the growth of tumor on human lung carcinoma bearing mice...