Research Topics
| Sayaka YoshibaSummaryAffiliation: Showa University Country: Japan Publications
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Detail Information
Publications
Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrestSayaka Yoshiba
Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University, Kitasenzoku 2 1 1, Ohta ku, Tokyo 145 8515, Japan
Oral Oncol 45:109-15. 2009..From these findings, we concluded that HS OSCC cells acquire 5-FU resistance under hypoxia by G(1)/S transition through an upregulation of cell cycle inhibitors...
Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cellsSayaka Takaoka
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Ota ku, Tokyo 145 8515, Japan
Int J Oncol 30:1469-76. 2007..These results suggest that EGFR inhibitors may represent a novel strategy for overcoming resistance to cisplatin-mediated apoptosis via the phosphatidylinositol 3-kinase/Akt pathway...
Epidermal growth factor receptor inhibitors enhance susceptibility to Fas-mediated apoptosis in oral squamous cell carcinoma cellsMasayasu Iwase
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, 2 1 1, Kitasenzoku, Ota ku, Tokyo 145 8515, Japan
Oral Oncol 44:361-8. 2008..These results suggest that the EGFR signaling pathway may, in part, regulate Fas-mediated apoptosis in OSCC cells through c-FLIP expression...
Enhanced susceptibility to apoptosis of oral squamous cell carcinoma cells subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitorsMasayasu Iwase
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Ota ku, Tokyo 145 8515, Japan
Int J Oncol 31:1141-7. 2007..These findings could potentially lead to new strategies for improving the efficacy of anticancer drugs in OSCC cells...
Antitumor activity of suberoylanilide hydroxamic acid against human oral squamous cell carcinoma cell lines in vitro and in vivoTatsuhito Nagumo
Department of Oral and Maxillofacial Surgery, Showa University, Kitasenzoku, Ohta ku, Tokyo, Japan
Oral Oncol 45:766-70. 2009..Additionally, we observed that the growth of xenograft SAS tumors in nude mice was significantly blocked by the administration of SAHA without major adverse effects...
Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosisSayaka Yoshiba
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, 2 1 1 Kitasenzoku, Ota ku, Tokyo 145 8515, Japan
Oncol Rep 25:645-52. 2011..The proteasome inhibitor MG132 may therefore represent a novel strategy for overcoming resistance to TRAIL-mediated apoptosis in OSCC cells...
Enhanced susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in oral squamous cell carcinoma cells treated with phosphatidylinositol 3-kinase inhibitorsMakiko Uchida
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo, Japan
Int J Oncol 30:1163-71. 2007..These results suggest that PI 3-K inhibitors may represent a novel strategy for overcoming resistance to TRAIL-mediated apoptosis in OSCC cells...
