T Shinki

Summary

Affiliation: Showa University
Country: Japan

Publications

  1. pmc Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA
    T Shinki
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    Proc Natl Acad Sci U S A 94:12920-5. 1997
  2. pmc Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats
    T Shinki
    Department of Biochemistry, School of Dentistry, Showa University, Hatanodai, Shinagawa ku, Tokyo 142 8555, USA
    Proc Natl Acad Sci U S A 96:8253-8. 1999
  3. pmc Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter
    H L Brenza
    Department of Biochemistry, University of Wisconsin Madison, 420 Henry Mall, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 95:1387-91. 1998
  4. ncbi request reprint Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function
    N Udagawa
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    Endocrinology 141:3478-84. 2000
  5. ncbi request reprint Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase
    T Monkawa
    School of Medicine, Keio University, Tokyo, Japan
    Biochem Biophys Res Commun 239:527-33. 1997
  6. ncbi request reprint Mitogen-activated protein kinases mediate interleukin-1beta-induced receptor activator of nuclear factor-kappaB ligand expression in human periodontal ligament cells
    A Oikawa
    Department of Periodontology, Showa University School of Dentistry, Tokyo, Japan
    J Periodontal Res 42:367-76. 2007
  7. ncbi request reprint Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF)
    Y H Gao
    Department of Oral Pathology, Department of Biochemistry, School of Dentistry, Showa University, 1 5 8 Hatanodai, Shinagawa ku, Tokyo, 142 8555, Japan
    Biochem Biophys Res Commun 252:697-702. 1998
  8. ncbi request reprint The specific production of the third component of complement by osteoblastic cells treated with 1 alpha,25-dihydroxyvitamin D3
    T Sato
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    FEBS Lett 285:21-4. 1991
  9. ncbi request reprint Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene
    Y Ohyama
    Graduate Department of Gene Science, Faculty of Science, Hiroshima University, Japan
    J Biol Chem 269:10545-50. 1994
  10. ncbi request reprint Microgravity generated by space flight has little effect on the growth and development of chick embryonic bone
    K Kawashima
    Department of Physiological Chemistry, Teikyo University, Sagamiko, Japan
    Biol Sci Space 9:82-94. 1995

Collaborators

Detail Information

Publications10

  1. pmc Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA
    T Shinki
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    Proc Natl Acad Sci U S A 94:12920-5. 1997
    ..In rats with the enhanced renal production of 1alpha,25-dihydroxyvitamin D3 (rats fed a low Ca diet), P4501alpha mRNA was greatly increased in the renal proximal convoluted tubules...
  2. pmc Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats
    T Shinki
    Department of Biochemistry, School of Dentistry, Showa University, Hatanodai, Shinagawa ku, Tokyo 142 8555, USA
    Proc Natl Acad Sci U S A 96:8253-8. 1999
    ..These results suggest that CT plays an important role in the maintenance of serum 1alpha,25(OH)2D3 under normocalcemic physiological conditions, at least in rats...
  3. pmc Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter
    H L Brenza
    Department of Biochemistry, University of Wisconsin Madison, 420 Henry Mall, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 95:1387-91. 1998
    ..These results indicate that parathyroid hormone stimulates 25-hydroxyvitamin D3-1alpha-hydroxylase by acting on the promoter of the 1alpha-hydroxylase gene...
  4. ncbi request reprint Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function
    N Udagawa
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    Endocrinology 141:3478-84. 2000
    ..These findings suggest that OPG produced by osteoblasts/stromal cells is a physiologically important regulator in osteoclast differentiation and function and that RANKL expressed by osteoblasts functions as a membrane-associated form...
  5. ncbi request reprint Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase
    T Monkawa
    School of Medicine, Keio University, Tokyo, Japan
    Biochem Biophys Res Commun 239:527-33. 1997
    ..This molecular cloning makes it possible to investigate the genetic mechanism of diseases related to calcium metabolism, including vitamin D-dependency rickets type I...
  6. ncbi request reprint Mitogen-activated protein kinases mediate interleukin-1beta-induced receptor activator of nuclear factor-kappaB ligand expression in human periodontal ligament cells
    A Oikawa
    Department of Periodontology, Showa University School of Dentistry, Tokyo, Japan
    J Periodontal Res 42:367-76. 2007
    ..We investigated herein the involvement of MAPKs in interleukin-1beta-stimulated RANKL expression in human periodontal ligament cells...
  7. ncbi request reprint Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF)
    Y H Gao
    Department of Oral Pathology, Department of Biochemistry, School of Dentistry, Showa University, 1 5 8 Hatanodai, Shinagawa ku, Tokyo, 142 8555, Japan
    Biochem Biophys Res Commun 252:697-702. 1998
    ..These results suggested that Cbfa1 is somehow involved in osteoclastogenesis through regulation of ODF/OPGL...
  8. ncbi request reprint The specific production of the third component of complement by osteoblastic cells treated with 1 alpha,25-dihydroxyvitamin D3
    T Sato
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    FEBS Lett 285:21-4. 1991
    ....
  9. ncbi request reprint Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene
    Y Ohyama
    Graduate Department of Gene Science, Faculty of Science, Hiroshima University, Japan
    J Biol Chem 269:10545-50. 1994
    ....
  10. ncbi request reprint Microgravity generated by space flight has little effect on the growth and development of chick embryonic bone
    K Kawashima
    Department of Physiological Chemistry, Teikyo University, Sagamiko, Japan
    Biol Sci Space 9:82-94. 1995
    ..Unlike the results of previous space flight experiments in which young growing mammals were used, these morphological and biochemical results indicate that microgravity has little effect on bone metabolism of the chick embryo...