H Ozawa

Summary

Affiliation: Showa University
Country: Japan

Publications

  1. ncbi request reprint Distinct functional characteristics of levocabastine sensitive rat neurotensin NT2 receptor expressed in Chinese hamster ovary cells
    M Yamada
    INSERM U339, Hopital Saint Antoine, Paris, France
    Life Sci 62:PL 375-80. 1998
  2. ncbi request reprint Clinical pharmacology of MAO inhibitors: safety and future
    Mitsuhiko Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, Tokyo 157 8577, Japan
    Neurotoxicology 25:215-21. 2004
  3. ncbi request reprint Induction of cysteine string protein after chronic antidepressant treatment in rat frontal cortex
    M Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, 157 8577, Tokyo, Japan
    Neurosci Lett 301:183-6. 2001
  4. ncbi request reprint Differential expression of VAMP2/synaptobrevin-2 after antidepressant and electroconvulsive treatment in rat frontal cortex
    M Yamada
    Department of Pharmacology, Showa University School of Pharmaceutical Sciences, Tokyo, Japan
    Pharmacogenomics J 2:377-82. 2002
  5. ncbi request reprint Functional genomics and depression research. Beyond the monoamine hypothesis
    Mitsuhiko Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, Tokyo 157 8577, Japan
    Eur Neuropsychopharmacol 12:235-44. 2002
  6. ncbi request reprint Identification of a novel gene with RING-H2 finger motif induced after chronic antidepressant treatment in rat brain
    M Yamada
    Department of Psychiatry, School of Medicine, Showa University, Tokyo 142 8666, Japan
    Biochem Biophys Res Commun 278:150-7. 2000
  7. ncbi request reprint PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway
    S Shioda
    Department of Anatomy, Showa University School of Medicine, Tokyo, Japan
    Ann N Y Acad Sci 865:111-7. 1998
  8. ncbi request reprint Early axonal and glial pathology in fetal sheep brains with leukomalacia induced by repeated umbilical cord occlusion
    J Ohyu
    Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan
    Brain Dev 21:248-52. 1999
  9. ncbi request reprint Tensile stress induces bone morphogenetic protein 4 in preosteoblastic and fibroblastic cells, which later differentiate into osteoblasts leading to osteogenesis in the mouse calvariae in organ culture
    M Ikegame
    Department of Pharmacology, Niigata University, Niigata-city, Japan
    J Bone Miner Res 16:24-32. 2001
  10. doi request reprint Identification, localisation and functional implication of 26RFa orthologue peptide in the brain of zebra finch (Taeniopygia guttata)
    Y Tobari
    Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
    J Neuroendocrinol 23:791-803. 2011

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Distinct functional characteristics of levocabastine sensitive rat neurotensin NT2 receptor expressed in Chinese hamster ovary cells
    M Yamada
    INSERM U339, Hopital Saint Antoine, Paris, France
    Life Sci 62:PL 375-80. 1998
    ..These findings suggest that NT1 and NT2 receptors present distinct functional characteristics and that SR48692 may act as a potent agonist for NT2 receptor...
  2. ncbi request reprint Clinical pharmacology of MAO inhibitors: safety and future
    Mitsuhiko Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, Tokyo 157 8577, Japan
    Neurotoxicology 25:215-21. 2004
    ..It seems obvious that a greater understanding of the pharmacodynamics and pharmacokinetics of MAOIs could result in improved treatment of the patients in the future...
  3. ncbi request reprint Induction of cysteine string protein after chronic antidepressant treatment in rat frontal cortex
    M Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, 157 8577, Tokyo, Japan
    Neurosci Lett 301:183-6. 2001
    ..In conclusion, our data suggest that CSP is one of the common functional molecules induced after chronic antidepressant treatment...
  4. ncbi request reprint Differential expression of VAMP2/synaptobrevin-2 after antidepressant and electroconvulsive treatment in rat frontal cortex
    M Yamada
    Department of Pharmacology, Showa University School of Pharmaceutical Sciences, Tokyo, Japan
    Pharmacogenomics J 2:377-82. 2002
    ..Our results may contribute to a novel model for the therapeutic mechanism of depression and new molecular targets for the development of therapeutic agents...
  5. ncbi request reprint Functional genomics and depression research. Beyond the monoamine hypothesis
    Mitsuhiko Yamada
    Department of Psychiatry, Showa University Karasuyama Hospital, 6 11 11 Kitakarasuyama, Setagaya, Tokyo 157 8577, Japan
    Eur Neuropsychopharmacol 12:235-44. 2002
    ..Novel biological approaches beyond the "monoamine hypothesis" are expected to evoke paradigm shifts in the future of depression research...
  6. ncbi request reprint Identification of a novel gene with RING-H2 finger motif induced after chronic antidepressant treatment in rat brain
    M Yamada
    Department of Psychiatry, School of Medicine, Showa University, Tokyo 142 8666, Japan
    Biochem Biophys Res Commun 278:150-7. 2000
    ..Our data suggest that ADRG34, a possible rat homologue of kf-1, may be one of the common functional molecules induced after chronic antidepressant treatment...
  7. ncbi request reprint PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway
    S Shioda
    Department of Anatomy, Showa University School of Medicine, Tokyo, Japan
    Ann N Y Acad Sci 865:111-7. 1998
    ..IL-6 inhibited the activation of JNK/SAPK, while it activated ERK. These observations suggest that PACAP and IL-6 act to inhibit the JNK/SAPK signaling pathway, thereby protecting neurons against apoptosis...
  8. ncbi request reprint Early axonal and glial pathology in fetal sheep brains with leukomalacia induced by repeated umbilical cord occlusion
    J Ohyu
    Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan
    Brain Dev 21:248-52. 1999
    ..These findings suggest the glial reaction of cytokines and free radicals induced by fetal hypoxia may contribute to the occurrence of brain injury...
  9. ncbi request reprint Tensile stress induces bone morphogenetic protein 4 in preosteoblastic and fibroblastic cells, which later differentiate into osteoblasts leading to osteogenesis in the mouse calvariae in organ culture
    M Ikegame
    Department of Pharmacology, Niigata University, Niigata-city, Japan
    J Bone Miner Res 16:24-32. 2001
    ..These results suggest that BMP-4 may play a pivotal role by acting as an autocrine and a paracrine factor for recruiting osteoblasts in tensile stress-induced osteogenesis...
  10. doi request reprint Identification, localisation and functional implication of 26RFa orthologue peptide in the brain of zebra finch (Taeniopygia guttata)
    Y Tobari
    Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
    J Neuroendocrinol 23:791-803. 2011
    ..Our data suggest that the hypothalamic 26RFa-its receptor system plays an important role in the central control of food intake and energy homeostasis in the zebra finch...
  11. doi request reprint The single-prolonged stress paradigm alters both the morphology and stress response of magnocellular vasopressin neurons
    T Yoshii
    Department of Psychiatry, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Neuroscience 156:466-74. 2008
    ..These findings suggest that AVP is a potential biomarker for past exposure to severe stress and that alterations in AVP may affect the development of pathogenesis in stress-related disorders...
  12. ncbi request reprint Silent mixed corticotroph and somatotroph macroadenomas presenting with pituitary apoplexy
    T Abe
    Department of Neurosurgery, Showa University School of Medicine, Tokyo, Japan
    Acta Neuropathol 102:435-40. 2001
    ....
  13. ncbi request reprint Immunolocalization of osteoclast differentiation factor in rat periodontium
    S Kawamoto
    Second Department of Prosthetic Dentistry, Kagoshima University Dental School, 8 35 1 Sakuragaoka, 890 8544, Kagoshima, Japan
    Arch Oral Biol 47:55-8. 2002
    ..Immunohistochemical examination for the general antigen of nerve-specific protein suggested a similarity between these structures and nerve fibres...
  14. ncbi request reprint Inefficient function of the signal sequence of PTHrP for targeting into the secretory pathway
    N Amizuka
    1st Department of Oral Anatomy, Department of Oral Biochemistry, Niigata University Faculty of Dentistry, 5274, 2 bancho, Gakkocho dori, Niigata, 951 8514, Japan
    Biochem Biophys Res Commun 273:621-9. 2000
    ..These results strongly indicate that the signal sequence of PTHrP is not sufficient to direct all the newly synthesized molecules across the endoplasmic reticulum, resulting in part of it being delivered to the nucleoli due to the NTS...
  15. ncbi request reprint Impairment of G(salpha) function in human brain cortex of Alzheimer's disease: comparison with normal aging
    E Hashimoto
    Clinical Neurochemistry and NPF Center of Excellence Research Labs, Department of Psychiatry, University of Wurzburg, Germany
    J Neural Transm 111:311-22. 2004
    ..These results suggest that the disturbances of post-receptor trans-membrane signalling in AD can be attributed to functional changes of G(salpha), and these are independent of alterations in the level for those proteins in normal aging...