Sadako Akashi-Tanaka

Summary

Affiliation: Showa University
Country: Japan

Publications

  1. doi request reprint Evaluation of the usefulness of breast CT imaging in delineating tumor extent and guiding surgical management: a prospective multi-institutional study
    Sadako Akashi-Tanaka
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg 256:157-62. 2012
  2. doi request reprint Preoperative CT evaluation of intraductal spread of breast cancer and surgical treatment
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 5 chome 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 20:21-5. 2013
  3. pmc The use of contrast-enhanced computed tomography before neoadjuvant chemotherapy to identify patients likely to be treated safely with breast-conserving surgery
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg 239:238-43. 2004
  4. doi request reprint Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104 0045, Japan
    Hum Pathol 42:998-1006. 2011
  5. doi request reprint p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Service, National Cancer Center, Chuo Ku, Tokyo, Japan
    Mod Pathol 23:662-72. 2010
  6. doi request reprint Grading system for lymph vessel tumor emboli: significant outcome predictor for patients with invasive ductal carcinoma of the breast who received neoadjuvant therapy
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Mod Pathol 23:581-92. 2010
  7. doi request reprint Important histologic outcome predictors for patients with invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center Hospital, Tokyo, Japan
    Am J Surg Pathol 35:1484-97. 2011
  8. doi request reprint Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Chuo Ku, 104 0045, Tokyo, Japan
    Hum Pathol 42:1823-32. 2011
  9. doi request reprint Evaluation of axillary status in patients with breast cancer using thin-section CT
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
    Int J Clin Oncol 13:314-9. 2008
  10. ncbi request reprint Favorable outcome in patients with breast cancer in the presence of pathological response after neoadjuvant endocrine therapy
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast 16:482-8. 2007

Collaborators

Detail Information

Publications30

  1. doi request reprint Evaluation of the usefulness of breast CT imaging in delineating tumor extent and guiding surgical management: a prospective multi-institutional study
    Sadako Akashi-Tanaka
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg 256:157-62. 2012
    ..The aim of the present study was to evaluate the usefulness of computed tomographic (CT) imaging in delineating tumor extent and guiding surgical management...
  2. doi request reprint Preoperative CT evaluation of intraductal spread of breast cancer and surgical treatment
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 5 chome 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 20:21-5. 2013
    ..Computed tomography carried out with the patient in the supine position accompanied by adequate marking is effective for preoperative determination of the optimum extent of BCS...
  3. pmc The use of contrast-enhanced computed tomography before neoadjuvant chemotherapy to identify patients likely to be treated safely with breast-conserving surgery
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg 239:238-43. 2004
    ..To select suitable candidates for breast-conserving treatment (BCT) after neoadjuvant chemotherapy (NAC), based on the classification of tumors into localized or diffuse types using contrast-enhanced computed tomography (CE-CT)...
  4. doi request reprint Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104 0045, Japan
    Hum Pathol 42:998-1006. 2011
    ....
  5. doi request reprint p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Service, National Cancer Center, Chuo Ku, Tokyo, Japan
    Mod Pathol 23:662-72. 2010
    ....
  6. doi request reprint Grading system for lymph vessel tumor emboli: significant outcome predictor for patients with invasive ductal carcinoma of the breast who received neoadjuvant therapy
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Mod Pathol 23:581-92. 2010
    ....
  7. doi request reprint Important histologic outcome predictors for patients with invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center Hospital, Tokyo, Japan
    Am J Surg Pathol 35:1484-97. 2011
    ..These findings strongly suggest that these histologic factors are very useful for accurately predicting the outcomes of patients with invasive ductal carcinoma of the breast...
  8. doi request reprint Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Chuo Ku, 104 0045, Tokyo, Japan
    Hum Pathol 42:1823-32. 2011
    ..In conclusion, this study clearly confirmed the excellent outcome predictive power of the number of mitotic figures in metastatic mammary carcinoma to the lymph nodes...
  9. doi request reprint Evaluation of axillary status in patients with breast cancer using thin-section CT
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
    Int J Clin Oncol 13:314-9. 2008
    ..We evaluated on the efficacy of preoperative axillary staging using contrast-enhanced computed tomography (CE-CT)...
  10. ncbi request reprint Favorable outcome in patients with breast cancer in the presence of pathological response after neoadjuvant endocrine therapy
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast 16:482-8. 2007
    ..Multivariate analysis of relapse-free survival indicated that pathological response was independent. Therefore, pathological response may be a favorable prognostic factor after NAET...
  11. ncbi request reprint Brain metastases after achieving local pathological complete responses with neoadjuvant chemotherapy
    Shunsuke Tsukamoto
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Breast Cancer 14:420-4. 2007
    ..We encountered two patients with inflammatory breast carcinoma who developed symptomatic brain metastases after achieving local pathological complete responses (pCR) with neoadjuvant chemotherapy (NAC)...
  12. doi request reprint Clinical efficacy of S-1 in pretreated metastatic breast cancer patients
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 38:172-5. 2008
    ..S-1, an oral fluoropyrimidine carbamate, is an active and well-tolerated agent against solid cancer. However, the clinical efficacy of S-1 in patients with metastatic breast cancer has not been determined...
  13. doi request reprint Atypical tumor-stromal fibroblasts in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center Research Institute, Chuo Ku, Tokyo, Japan
    Am J Surg Pathol 35:325-36. 2011
    ....
  14. doi request reprint Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome
    Tadahiko Shien
    Department of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Breast Cancer Res Treat 113:307-13. 2009
    ..All three classifications analyzed were considered inadequate as the prognostic marker of the long-term outcome after NAC and further studies are warranted to optimize the prediction...
  15. doi request reprint p53 expression in tumor stromal fibroblasts is associated with the outcome of patients with invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Cancer Sci 100:2101-8. 2009
    ..The results indicated that p53 protein expression in tumor stromal fibroblasts is closely associated with the number of nodal metastases and the outcome of IDC patients...
  16. doi request reprint Prognostic factors in young Japanese women with breast cancer: prognostic value of age at diagnosis
    Miwa Yoshida
    Division of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 41:180-9. 2011
    ..The secondary objective was to assess prognostic factors specific for younger premenopausal patients...
  17. doi request reprint Usefulness of preoperative multidetector-row computed tomography in evaluating the extent of invasive lobular carcinoma in patients with or without neoadjuvant chemotherapy
    Tadahiko Shien
    Division of Breast Surgery, National Cancer Center Hospital, 1 1 5 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:30-6. 2009
    ..The present study was conducted to assess the clinical usefulness of multidetector-row CT (MDCT) in determining the extent of invasive lobular carcinoma (ILC) and especially the extent of residual tumor after neoadjuvant chemotherapy (NAC)...
  18. doi request reprint Feasibility of breast conserving surgery for Paget's disease
    Shunsuke Onoe
    Breast Cancer Group, Surgical Oncology Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast 20:515-8. 2011
    ..The standard treatment for Paget's disease of the breast is mastectomy. Since it is frequently associated with underlying carcinoma, many surgeons are reluctant to choose breast conserving surgery for Paget's disease...
  19. ncbi request reprint Intracystic papillary carcinoma of the breast in a male patient diagnosed by core needle biopsy: a case report
    Takayuki Kinoshita
    Surgical Oncology Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast 14:322-4. 2005
    ..So the patient underwent simple mastectomy without axillary node biopsy. From the final pathological result, no invasion was identified...
  20. ncbi request reprint Sentinel lymph node biopsy examination for breast cancer patients with clinically negative axillary lymph nodes after neoadjuvant chemotherapy
    Takayuki Kinoshita
    Division of Surgical Oncology, National Cancer Center Hospital, 5 1 1, Tsukiji Chuo ku, Tokyo 104 0045, Japan
    Am J Surg 191:225-9. 2006
    ..In addition, conditions that may affect SLN biopsy detection and false-negative rates with respect to clinical tumor response and clinical nodal status before NAC were analyzed...
  21. doi request reprint Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spread
    Sadako Akashi-Tanaka
    Department of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:62-7. 2009
    ....
  22. doi request reprint Synchronous unilateral triple breast cancers composed of invasive ductal carcinoma, invasive lobular carcinoma, and Paget's disease
    Shunsuke Onoe
    Pathology Section, Clinical Laboratory Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuoku, Tokyo, 104 0045, Japan
    Breast Cancer 21:241-5. 2014
    ..Cases of synchronous unilateral triple or more breast cancers were reviewed, and their histopathological characteristics, including the incidence of Paget's disease, is discussed. ..
  23. ncbi request reprint The role of computed tomography in the selection of breast cancer treatment
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast Cancer 10:198-203. 2003
    ..The sensitivity and specificity are 79-90% and 70-89%, respectively; (4) to identify occult breast cancer with axillary metastasis and to diagnose local recurrence after BCT...
  24. doi request reprint Loss of heterozygosity on chromosome 16q suggests malignancy in core needle biopsy specimens of intraductal papillary breast lesions
    Miwa Yoshida
    Division of Diagnostic Pathology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Virchows Arch 460:497-504. 2012
    ..007). Analysis of LOH on 16q may be helpful in making a definitive diagnosis in cases of papillary breast lesions, in both excised and CNB specimens...
  25. ncbi request reprint Histological grade, p53, HER2 and hormone receptor status of synchronous bilateral breast carcinoma
    Kaneyuki Matsuo
    Department of Surgical Oncology, National Cancer Center Hospital, 1 1, Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast Cancer 9:127-33. 2002
    ..We analyzed the clinicopathological characteristics and tumor biology with regard to histological grade (HG), p53, HER2 and hormone receptor status to address this question...
  26. doi request reprint Up-regulation of PSF1 promotes the growth of breast cancer cells
    Izumi Nakahara
    Center for Medical Genomics, National Cancer Center Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Genes Cells 15:1015-24. 2010
    ..These results suggest that PSF1 over-expression is specifically involved in breast cancer cell growth. Therefore, PSF1 inhibition might provide new therapeutic approaches for breast cancer...
  27. doi request reprint Predicting responses to chemotherapy in breast cancer: from bench to bedside
    Sadako Akashi-Tanaka
    Division of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast Cancer 17:92-6. 2010
    ..Some predictive or prognostic tests for breast cancer are now moving from bench to bedside...
  28. doi request reprint Tumor histology in lymph vessels and lymph nodes for the accurate prediction of outcome among breast cancer patients treated with neoadjuvant chemotherapy
    Nobuko Tamura
    Department of Breast Surgery, National Cancer Center Hospital, Chuo Ku, Tokyo
    Cancer Sci 100:1823-33. 2009
    ....
  29. doi request reprint Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation
    Mizuho Kikuyama
    Division of Epigenomics, National Cancer Center Research Institute, Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Lett 322:204-12. 2012
    ..These results showed that the epigenome-based outlier approach is capable of identifying a different set of TSGs, compared to the expression-based outlier approach...
  30. doi request reprint Clinical and pathological features of intracystic papillary carcinoma of the breast
    Tomonori Akagi
    Division of Breast Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Surg Today 39:5-8. 2009
    ..To evaluate the clinicopathological features of intracystic papillary carcinoma (ICPC), which have not been established given its rarity and lack of standard diagnostic criteria...