Takashi Ushimaru

Summary

Affiliation: Shizuoka University
Country: Japan

Publications

  1. ncbi Transgenic Arabidopsis plants expressing the rice dehydroascorbate reductase gene are resistant to salt stress
    Takashi Ushimaru
    Department of Biology and Geoscience, Faculty of Science, Shizuoka University, 836 Ohya, Shizuoka 422 8529, Japan
    J Plant Physiol 163:1179-84. 2006
  2. pmc APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage
    Kazuhiro Toda
    Faculty of Science, Shizuoka University, Shizuoka University, Shizuoka 422 8529, Japan
    Cell Div 7:4. 2012
  3. ncbi [Regulation of ribosome biogenesis by the protein kinase TOR in response to nutrient availability]
    Takashi Ushimaru
    Tanpakushitsu Kakusan Koso 52:342-7. 2007
  4. ncbi Chloroplasts in seeds and dark-grown seedlings of lotus
    Takashi Ushimaru
    Department of Biology and Geosciences, Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
    J Plant Physiol 160:321-4. 2003
  5. ncbi A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe
    Akio Nakashima
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, 422 8539, Shizuoka, Japan
    Curr Genet 49:403-13. 2006
  6. pmc Fission yeast Dna2 is required for generation of the telomeric single-strand overhang
    Kazunori Tomita
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Mol Cell Biol 24:9557-67. 2004
  7. pmc A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation
    Yuuki Ono
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 31:7141-9. 2003
  8. pmc Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer
    Tatsuya Kibe
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 31:5054-63. 2003
  9. pmc Fission yeast Arp6 is required for telomere silencing, but functions independently of Swi6
    Masaru Ueno
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 32:736-41. 2004
  10. ncbi Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase
    Masahiro Uritani
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya Suruga ku, Shizuoka 422 8529, Japan
    Genes Cells 11:1367-79. 2006

Collaborators

Detail Information

Publications24

  1. ncbi Transgenic Arabidopsis plants expressing the rice dehydroascorbate reductase gene are resistant to salt stress
    Takashi Ushimaru
    Department of Biology and Geoscience, Faculty of Science, Shizuoka University, 836 Ohya, Shizuoka 422 8529, Japan
    J Plant Physiol 163:1179-84. 2006
    ..Salt tolerance was remarkably improved despite slight increases in DHAR activity and total ascorbate. This study provides direct evidence for the importance of DHAR in salt tolerance...
  2. pmc APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage
    Kazuhiro Toda
    Faculty of Science, Shizuoka University, Shizuoka University, Shizuoka 422 8529, Japan
    Cell Div 7:4. 2012
    ..abstract:..
  3. ncbi [Regulation of ribosome biogenesis by the protein kinase TOR in response to nutrient availability]
    Takashi Ushimaru
    Tanpakushitsu Kakusan Koso 52:342-7. 2007
  4. ncbi Chloroplasts in seeds and dark-grown seedlings of lotus
    Takashi Ushimaru
    Department of Biology and Geosciences, Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
    J Plant Physiol 160:321-4. 2003
    ..These shoots contain chlorophyll and chlorophyll-binding proteins CP1 and LHCP. The unique features of chloroplast formation in N. nucifera suggest a unique adaptive strategy for seedling development correlated with the plant's habitat...
  5. ncbi A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe
    Akio Nakashima
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, 422 8539, Shizuoka, Japan
    Curr Genet 49:403-13. 2006
    ..These observations suggest that isp6(+) contributes to sexual development by providing a nitrogen source through autophagy...
  6. pmc Fission yeast Dna2 is required for generation of the telomeric single-strand overhang
    Kazunori Tomita
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Mol Cell Biol 24:9557-67. 2004
    ..Our results reveal that DSB ends and telomere ends are processed by different mechanisms...
  7. pmc A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation
    Yuuki Ono
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 31:7141-9. 2003
    ..cerevisiae rfa1-D228Y mutation, the rad11-D223Y mutation itself caused telomere shortening. Moreover, Rad11-Myc bound to telomere in a ChIP assay. These results strongly suggest that RPA is directly involved in telomere maintenance...
  8. pmc Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer
    Tatsuya Kibe
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 31:5054-63. 2003
    ..Our results suggest that, although Ku heterodimer sequesters Rhp51 from telomere ends to inhibit homologous recombination activity, Rhp51 plays important roles for the maintenance of telomere ends in the absence of the Ku heterodimer...
  9. pmc Fission yeast Arp6 is required for telomere silencing, but functions independently of Swi6
    Masaru Ueno
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Nucleic Acids Res 32:736-41. 2004
    ..These results suggest that Arp6 and Swi6 function independently at telomere ends. We propose that the Arp6-mediated repression mechanism works side by side with Swi6-based telomere silencing in S.pombe...
  10. ncbi Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase
    Masahiro Uritani
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya Suruga ku, Shizuoka 422 8529, Japan
    Genes Cells 11:1367-79. 2006
    ..We propose that Tor1 and Tor2 are involved in both corroborative and independent roles in nutrient sensing and stress response pathways...
  11. ncbi Sequence-specific binding of the Schizosaccharomyces pombe His1 protein to fission yeast telomeric DNA
    Kazunori Tomita
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Chem Biodivers 1:1344-53. 2004
    ..Previously identified sequence-specific telomere-binding proteins contain Myb domain. In contrast, Schizosaccharomyces pombe His1 does not contain Myb domain. These findings indicate that His1 has a novel DNA-recognition domain...
  12. pmc TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients
    Yoshimi Honma
    Faculty of Science, Shizuoka University, Shizuoka, Japan
    EMBO J 25:3832-42. 2006
    ..Thus, the Nog1 complex is a critical regulator of ribosome biogenesis mediated by TOR. This is the first description of a physiological regulation of nucleolus-to-nucleoplasm translocation of pre-ribosome complexes...
  13. ncbi Sorting defects of the tryptophan permease Tat2 in an erg2 yeast mutant
    Katsue Daicho
    Faculty of Science, Shizuoka University, Shizuoka, Japan
    FEMS Microbiol Lett 298:218-27. 2009
    ..This study suggests the potential for the pharmacological control of cellular nutrient uptake in humans by regulating enzymes involved in cholesterol biogenesis...
  14. ncbi Involvement of a CCAAT-binding complex in the expression of a nitrogen-starvation-specific gene, isp6+, in Schizosaccharomyces pombe
    Akio Nakashima
    Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Biosci Biotechnol Biochem 66:2224-7. 2002
    ..The CCAAT-binding complex also was involved in the induction of isp6+ during nitrogen starvation...
  15. ncbi The ergosterol biosynthesis inhibitor zaragozic acid promotes vacuolar degradation of the tryptophan permease Tat2p in yeast
    Katsue Daicho
    Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
    Biochim Biophys Acta 1768:1681-90. 2007
    ..The degradation of Tat2p was dependent on the Rsp5p-mediated ubiquitination of Tat2p and was not suppressed by deletions of VPS1, VPS27, VPS45 or PEP12. We will discuss ZA-mediated Tat2p degradation in the context of lipid rafts...
  16. pmc Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres
    Kazunori Tomita
    Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
    Mol Cell Biol 23:5186-97. 2003
    ..While we have identified Exo1 as the alternative nuclease targeting DNA break sites, the identity of the nuclease acting on the telomere ends remains elusive...
  17. ncbi A novel non-conventional heat shock element regulates expression of MDJ1 encoding a DnaJ homolog in Saccharomyces cerevisiae
    Tomohusa Tachibana
    Department of Biology and Geoscience, Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
    J Biol Chem 277:22140-6. 2002
    ..ncHSE(MDJ1)-like elements are found in promoter regions of some other DnaJ-related genes. The highly conserved HSF/HSE system suggests that similar ncHSEs may be used for the expression of HSP genes in other eukaryotes including humans...
  18. pmc Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1
    Aktar Uzzaman Chouduri
    Department of Biology, Faculty of Science, National University Corporation, Shizuoka University, 836 Oya, Suruga ku, Shizuoka 422 8529, Japan
    BMC Biochem 9:20. 2008
    ..In this study, peptidase activities, activation profiles, and the subunit composition of the 20S proteasome purified from the rpt6-1 mutant was characterized...
  19. pmc Apoptosis at inflection point in liquid culture of budding yeasts
    Toshiyuki Hagiwara
    Graduate School of Science and Technology, Shizuoka University, Hamamatsu, Japan
    PLoS ONE 6:e19224. 2011
    ..This discrepancy is confirmed directly by the microscopic observations of broken cells. This finding implies apoptosis in older cells (6 scars or more)...
  20. ncbi New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound
    Shigeru Nakaya
    Faculty of Science, Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan
    Biosci Biotechnol Biochem 76:1226-8. 2012
    ..The new assay is simple, convenient and labor-saving. We applied this new method to screen natural compounds isolated from mushrooms and discovered beauveriolide I as a potent anti-aging agent...
  21. ncbi Anti-aging and anti-microbial effects of melleolide on various types of yeast
    Shigeru Nakaya
    a Faculty of Science, Shizuoka University, Shizuoka, Japan
    Biosci Biotechnol Biochem 78:455-7. 2014
    ..This indicates that melleolide might have a potential anti-aging activity against some types of cell, and that it might be useful as a selective anti-fungal drug. ..
  22. ncbi Stage-dependent density effect in the cell cycle of budding yeast
    Kei ichi Tainaka
    Department of Systems Engineering, Shizuoka University, Hamamatsu 432 8561, Japan
    J Theor Biol 242:736-42. 2006
    ..Our results imply the existence of an inhibitor that specifically halts the reproduction of matured daughter cell...
  23. ncbi Genes for a nuclease and a protease are involved in the drastic decrease in cellular RNA amount in fission yeast cells during nitrogen starvation
    Akio Nakashima
    Department of Chemistry, Faculty of Science, Shizuoka University, Oya, Shizuoka 422 8529, Japan
    J Biochem 131:391-8. 2002
    ....
  24. ncbi Heterologous expression of dehydroascorbate reductase from rice and its application to determination of dehydroascorbate concentrations
    Katsumi Amako
    Faculty of Nutrition, Kobe Gakuin University, Japan
    J Nutr Sci Vitaminol (Tokyo) 52:89-95. 2006
    ..Using recombinant DHAR, we developed a method for simple and precise determination of dehydroascorbate concentrations in tissue extracts by spectrophotometry, and we successfully applied the method to several fruit juices and vegetables...