Research Topics
Genomes and Genes | Takashi UshimaruSummaryAffiliation: Shizuoka University Country: Japan Publications
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Detail Information
Publications
APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippageKazuhiro Toda
Faculty of Science, Shizuoka University, Shizuoka University, Shizuoka 422 8529, Japan
Cell Div 7:4. 2012..abstract:..
Transgenic Arabidopsis plants expressing the rice dehydroascorbate reductase gene are resistant to salt stressTakashi Ushimaru
Department of Biology and Geoscience, Faculty of Science, Shizuoka University, 836 Ohya, Shizuoka 422 8529, Japan
J Plant Physiol 163:1179-84. 2006..Salt tolerance was remarkably improved despite slight increases in DHAR activity and total ascorbate. This study provides direct evidence for the importance of DHAR in salt tolerance...- Chloroplasts in seeds and dark-grown seedlings of lotusTakashi Ushimaru
Department of Biology and Geosciences, Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
J Plant Physiol 160:321-4. 2003..These shoots contain chlorophyll and chlorophyll-binding proteins CP1 and LHCP. The unique features of chloroplast formation in N. nucifera suggest a unique adaptive strategy for seedling development correlated with the plant's habitat... - [Regulation of ribosome biogenesis by the protein kinase TOR in response to nutrient availability]Takashi Ushimaru
Tanpakushitsu Kakusan Koso 52:342-7. 2007 - A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombeAkio Nakashima
Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, 422 8539, Shizuoka, Japan
Curr Genet 49:403-13. 2006..These observations suggest that isp6(+) contributes to sexual development by providing a nitrogen source through autophagy... - Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimerTatsuya Kibe
Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
Nucleic Acids Res 31:5054-63. 2003..Our results suggest that, although Ku heterodimer sequesters Rhp51 from telomere ends to inhibit homologous recombination activity, Rhp51 plays important roles for the maintenance of telomere ends in the absence of the Ku heterodimer... - A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulationYuuki Ono
Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
Nucleic Acids Res 31:7141-9. 2003..cerevisiae rfa1-D228Y mutation, the rad11-D223Y mutation itself caused telomere shortening. Moreover, Rad11-Myc bound to telomere in a ChIP assay. These results strongly suggest that RPA is directly involved in telomere maintenance... - Fission yeast Dna2 is required for generation of the telomeric single-strand overhangKazunori Tomita
Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
Mol Cell Biol 24:9557-67. 2004..Our results reveal that DSB ends and telomere ends are processed by different mechanisms... - Fission yeast Arp6 is required for telomere silencing, but functions independently of Swi6Masaru Ueno
Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
Nucleic Acids Res 32:736-41. 2004..These results suggest that Arp6 and Swi6 function independently at telomere ends. We propose that the Arp6-mediated repression mechanism works side by side with Swi6-based telomere silencing in S.pombe... - Sequence-specific binding of the Schizosaccharomyces pombe His1 protein to fission yeast telomeric DNAKazunori Tomita
Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422-8529, Japan
Chem Biodivers 1:1344-53. 2004..Previously identified sequence-specific telomere-binding proteins contain Myb domain. In contrast, Schizosaccharomyces pombe His1 does not contain Myb domain. These findings indicate that His1 has a novel DNA-recognition domain... 
Sorting defects of the tryptophan permease Tat2 in an erg2 yeast mutantKatsue Daicho
Faculty of Science, Shizuoka University, Shizuoka, Japan
FEMS Microbiol Lett 298:218-27. 2009..This study suggests the potential for the pharmacological control of cellular nutrient uptake in humans by regulating enzymes involved in cholesterol biogenesis...- TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrientsYoshimi Honma
Faculty of Science, Shizuoka University, Shizuoka, Japan
EMBO J 25:3832-42. 2006..Thus, the Nog1 complex is a critical regulator of ribosome biogenesis mediated by TOR. This is the first description of a physiological regulation of nucleolus-to-nucleoplasm translocation of pre-ribosome complexes... - Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPaseMasahiro Uritani
Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya Suruga ku, Shizuoka 422 8529, Japan
Genes Cells 11:1367-79. 2006..We propose that Tor1 and Tor2 are involved in both corroborative and independent roles in nutrient sensing and stress response pathways... - Involvement of a CCAAT-binding complex in the expression of a nitrogen-starvation-specific gene, isp6+, in Schizosaccharomyces pombeAkio Nakashima
Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, Shizuoka 422-8529, Japan
Biosci Biotechnol Biochem 66:2224-7. 2002..The CCAAT-binding complex also was involved in the induction of isp6+ during nitrogen starvation... - The ergosterol biosynthesis inhibitor zaragozic acid promotes vacuolar degradation of the tryptophan permease Tat2p in yeastKatsue Daicho
Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
Biochim Biophys Acta 1768:1681-90. 2007..The degradation of Tat2p was dependent on the Rsp5p-mediated ubiquitination of Tat2p and was not suppressed by deletions of VPS1, VPS27, VPS45 or PEP12. We will discuss ZA-mediated Tat2p degradation in the context of lipid rafts... - Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1Aktar Uzzaman Chouduri
Department of Biology, Faculty of Science, National University Corporation, Shizuoka University, 836 Oya, Suruga ku, Shizuoka 422 8529, Japan
BMC Biochem 9:20. 2008..In this study, peptidase activities, activation profiles, and the subunit composition of the 20S proteasome purified from the rpt6-1 mutant was characterized... - A novel non-conventional heat shock element regulates expression of MDJ1 encoding a DnaJ homolog in Saccharomyces cerevisiaeTomohusa Tachibana
Department of Biology and Geoscience, Faculty of Science, Shizuoka University, Shizuoka 422-8529, Japan
J Biol Chem 277:22140-6. 2002..ncHSE(MDJ1)-like elements are found in promoter regions of some other DnaJ-related genes. The highly conserved HSF/HSE system suggests that similar ncHSEs may be used for the expression of HSP genes in other eukaryotes including humans... - Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeresKazunori Tomita
Department of Chemistry, Shizuoka University, 836 Oya, Shizuoka 422 8529, Japan
Mol Cell Biol 23:5186-97. 2003..While we have identified Exo1 as the alternative nuclease targeting DNA break sites, the identity of the nuclease acting on the telomere ends remains elusive... - Apoptosis at inflection point in liquid culture of budding yeastsToshiyuki Hagiwara
Graduate School of Science and Technology, Shizuoka University, Hamamatsu, Japan
PLoS ONE 6:e19224. 2011..This discrepancy is confirmed directly by the microscopic observations of broken cells. This finding implies apoptosis in older cells (6 scars or more)... - New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compoundShigeru Nakaya
Faculty of Science, Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan
Biosci Biotechnol Biochem 76:1226-8. 2012..The new assay is simple, convenient and labor-saving. We applied this new method to screen natural compounds isolated from mushrooms and discovered beauveriolide I as a potent anti-aging agent... - Stage-dependent density effect in the cell cycle of budding yeastKei ichi Tainaka
Department of Systems Engineering, Shizuoka University, Hamamatsu 432 8561, Japan
J Theor Biol 242:736-42. 2006..Our results imply the existence of an inhibitor that specifically halts the reproduction of matured daughter cell... - Genes for a nuclease and a protease are involved in the drastic decrease in cellular RNA amount in fission yeast cells during nitrogen starvationAkio Nakashima
Department of Chemistry, Faculty of Science, Shizuoka University, Oya, Shizuoka 422 8529, Japan
J Biochem 131:391-8. 2002.... - Heterologous expression of dehydroascorbate reductase from rice and its application to determination of dehydroascorbate concentrationsKatsumi Amako
Faculty of Nutrition, Kobe Gakuin University, Japan
J Nutr Sci Vitaminol (Tokyo) 52:89-95. 2006..Using recombinant DHAR, we developed a method for simple and precise determination of dehydroascorbate concentrations in tissue extracts by spectrophotometry, and we successfully applied the method to several fruit juices and vegetables...