Genomes and Genes


Keiichi Hatakeyama


Affiliation: Shizuoka Cancer Center
Country: Japan


  1. Hatakeyama K, Ohshima K, Nagashima T, Ohnami S, Ohnami S, Serizawa M, et al. Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations. Sci Rep. 2018;8:8700 pubmed publisher
    ..Our strategy for estimation of the footprint of somatic mutations may provide new insight towards the understanding of mutation-driven tumourigenesis. ..
  2. Hatakeyama K, Fukuda Y, Ohshima K, Terashima M, Yamaguchi K, Mochizuki T. Placenta-specific novel splice variants of Rho GDP dissociation inhibitor ? are highly expressed in cancerous cells. BMC Res Notes. 2012;5:666 pubmed publisher
    ..Expression of ARHGDIB variants 6a, 6b, and 6c appears to be restricted to cancer cells and normal placental tissue, suggesting that these variants possess cancer-specific functions and, as such, are potential cancer-related biomarkers. ..