- Two cases of breast carcinoma with osteoclastic giant cells: are the osteoclastic giant cells pro-tumoural differentiation of macrophages?Yukiko Shishido-Hara
Department of Pathology, Kyorin University School of Medicine 6 20 2, Shinkawa, Mitaka, Tokyo 181 8611, Japan
Diagn Pathol 5:55. 2010..Appearance of OGCs may not be anti-tumoural immunological reactions, but rather pro-tumoural differentiation of macrophage responding to hypervascular microenvironments induced by breast cancer...
- Promyelocytic leukemia nuclear bodies provide a scaffold for human polyomavirus JC replication and are disrupted after development of viral inclusions in progressive multifocal leukoencephalopathyYukiko Shishido-Hara
Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, Tokyo
J Neuropathol Exp Neurol 67:299-308. 2008....
- Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating diseaseYukiko Shishido-Hara
Department of Pathology, Kyorin University School of Medicine, Mitaka, Tokyo 181 8611, Japan
Acta Neuropathol 120:403-17. 2010..Here, we review what we have learned since the disease entity establishment, including a look at recent progress in understanding the relationship between JC virus, etiology and PML-NBs...
- JC virus intranuclear inclusions associated with PML-NBs: analysis by electron microscopy and structured illumination microscopyYukiko Shishido-Hara
Department of Pathology, Kyorin University School of Medicine, Tokyo, Japan
Am J Pathol 180:1095-106. 2012..Either the agnogene or its product likely supports efficient progeny production at PML-NBs, leading to subsequent degeneration of host glial cells...
- Major and minor capsid proteins of human polyomavirus JC cooperatively accumulate to nuclear domain 10 for assembly into virionsYukiko Shishido-Hara
Department of Microbiology, Tokyo Metropolitan Institute for Neuroscience, Japan
J Virol 78:9890-903. 2004..These results indicate that major and minor capsid proteins cooperatively accumulate in ND10, where they are efficiently assembled into virions...
- [Development of intranuclear inclusions of human polyomavirus JC. Capsid proteins are assembled into virions at the PML nuclear bodies]Yukiko Shishido-Hara
Department of Pathology, Kyorin University School of Medicine, 6 20 2, Shinkawa, Mitaka, Tokyo, 181 18611, Japan
Uirusu 56:17-25. 2006..The finding that the target of JCV infection is the PML-NB may contribute greatly to our understanding of the mechanism underlying cellular degeneration, which occurs after the formation of intranuclear viral inclusions...