Hirofumi Aoki

Summary

Affiliation: Shiseido Research Center
Country: Japan

Publications

  1. ncbi request reprint Upregulation of the IFN-gamma-stimulated genes in the development of delayed pigmented spots on the dorsal skin of F1 mice of HR-1 x HR/De
    Hirofumi Aoki
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa, Japan
    J Invest Dermatol 124:1053-61. 2005
  2. ncbi request reprint Gene expression profiling analysis of solar lentigo in relation to immunohistochemical characteristics
    H Aoki
    Shiseido Research Center, 2 12 2 Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa 236 8643, Japan
    Br J Dermatol 156:1214-23. 2007
  3. doi request reprint Immunohistochemical survey of the distribution of epidermal melanoblasts and melanocytes during the development of UVB-induced pigmented spots
    Rikako Furuya
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama 236 8643, Japan
    J Dermatol Sci 55:99-107. 2009
  4. doi request reprint Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction
    Shunsuke Iriyama
    Shiseido Research Center, 2 2 1 Hayabuchi, Tsuzuki ku, Yokohama 224 8558, Japan
    J Dermatol Sci 64:223-8. 2011
  5. doi request reprint Expressions of rod and cone photoreceptor-like proteins in human epidermis
    Moe Tsutsumi
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama, Japan
    Exp Dermatol 18:567-70. 2009
  6. ncbi request reprint Involvement of microphthalmia-associated transcription factor (MITF) in expression of human melanocortin-1 receptor (MC1R)
    Hirofumi Aoki
    Shiseido Research Center, 2 2 1 Hayabuchi, Tsuzuki ku, Yokohama shi, Kanagawa 224 8558, Japan
    Life Sci 71:2171-9. 2002

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Upregulation of the IFN-gamma-stimulated genes in the development of delayed pigmented spots on the dorsal skin of F1 mice of HR-1 x HR/De
    Hirofumi Aoki
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa, Japan
    J Invest Dermatol 124:1053-61. 2005
    ..Reciprocal activation among these cells to maintain this interactive network results in constitutive melanocyte activation and chronic melanin synthesis in delayed pigmented lesions...
  2. ncbi request reprint Gene expression profiling analysis of solar lentigo in relation to immunohistochemical characteristics
    H Aoki
    Shiseido Research Center, 2 12 2 Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa 236 8643, Japan
    Br J Dermatol 156:1214-23. 2007
    ..Although considerable knowledge about acute pigmentation has recently been accumulated, little is yet known about the mechanisms underlying chronic- and delayed-type hyperpigmentation, such as solar lentigo...
  3. doi request reprint Immunohistochemical survey of the distribution of epidermal melanoblasts and melanocytes during the development of UVB-induced pigmented spots
    Rikako Furuya
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama 236 8643, Japan
    J Dermatol Sci 55:99-107. 2009
    ..Repeated exposures to ultraviolet B radiation (UVB) induce pigmented spots on dorsal skin of (HR-1 x HR/De) F(1) hairless mouse. We showed previously that this mouse is suitable for studies of melanocyte function...
  4. doi request reprint Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction
    Shunsuke Iriyama
    Shiseido Research Center, 2 2 1 Hayabuchi, Tsuzuki ku, Yokohama 224 8558, Japan
    J Dermatol Sci 64:223-8. 2011
    ..However, it is not clear whether heparanase-induced loss of heparan sulfate at the DEJ is involved in the pigmentation process in sun-exposed skin...
  5. doi request reprint Expressions of rod and cone photoreceptor-like proteins in human epidermis
    Moe Tsutsumi
    Shiseido Research Center, Fukuura, Kanazawa Ku, Yokohama, Japan
    Exp Dermatol 18:567-70. 2009
    ..PCR analysis confirmed the expression of rhodopsin-like and opsin-like genes in human retina and the skin. These results suggest that a series of proteins, which play a crucial role in visual perception, are expressed in human epidermis...
  6. ncbi request reprint Involvement of microphthalmia-associated transcription factor (MITF) in expression of human melanocortin-1 receptor (MC1R)
    Hirofumi Aoki
    Shiseido Research Center, 2 2 1 Hayabuchi, Tsuzuki ku, Yokohama shi, Kanagawa 224 8558, Japan
    Life Sci 71:2171-9. 2002
    ..These results suggested that MITF regulates not only the expression of enzymes involved in melanin synthesis, but also the expression of a receptor which plays an essential role in melanocyte functions...