K Yasui

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. ncbi request reprint Roles of phosphatidylinositol 3-kinase and phospholipase D in temporal activation of superoxide production in FMLP-stimulated human neutrophils
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto 390, Japan
    Cell Biochem Funct 19:43-50. 2001
  2. doi request reprint Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism
    K Yasui
    Department of Pediatrics, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan
    Clin Exp Allergy 39:1857-65. 2009
  3. ncbi request reprint Thalidomide prevents formation of multinucleated giant cells (Langhans-type cells) from cultured monocytes: possible pharmaceutical applications for granulomatous disorders
    K Yasui
    Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Int J Immunopathol Pharmacol 22:707-14. 2009
  4. ncbi request reprint Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    J Leukoc Biol 67:529-35. 2000
  5. ncbi request reprint Presenility of granulocytes in Down syndrome individuals
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Am J Med Genet 84:406-12. 1999
  6. ncbi request reprint Effects of theophylline on human eosinophil functions: comparative study with neutrophil functions
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    J Leukoc Biol 68:194-200. 2000
  7. pmc Pentoxifylline and CD14 antibody additively inhibit priming of polymorphonuclear leukocytes for enhanced release of superoxide by lipopolysaccharide: possible mechanism of these actions
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Infect Immun 62:922-7. 1994
  8. doi request reprint The effect of ascorbate on minor recurrent aphthous stomatitis
    K Yasui
    Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Acta Paediatr 99:442-5. 2010
  9. pmc Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome
    K Agematsu
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto 390, Japan
    J Clin Invest 102:853-60. 1998
  10. ncbi request reprint New clinical applications of xanthine derivatives: modulatory actions on leukocyte survival and function
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Int J Hematol 73:87-92. 2001

Detail Information

Publications14

  1. ncbi request reprint Roles of phosphatidylinositol 3-kinase and phospholipase D in temporal activation of superoxide production in FMLP-stimulated human neutrophils
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto 390, Japan
    Cell Biochem Funct 19:43-50. 2001
    ..NADPH oxidase is activated in a PI3-kinase-dependent manner at the early phase, and PLD activity follows it and is related to superoxide production at the late phase in human neutrophils by stimulation with FMLP...
  2. doi request reprint Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism
    K Yasui
    Department of Pediatrics, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan
    Clin Exp Allergy 39:1857-65. 2009
    ..Dendritic cells (DCs) are professional antigen-presenting cells, capable of priming naïve T cells, and play key roles in the activation of immune responses in asthma...
  3. ncbi request reprint Thalidomide prevents formation of multinucleated giant cells (Langhans-type cells) from cultured monocytes: possible pharmaceutical applications for granulomatous disorders
    K Yasui
    Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Int J Immunopathol Pharmacol 22:707-14. 2009
    ..Our results support thalidomides clinical efficacy in the treatment of chronic granulomatous disorders (granulomatosis)...
  4. ncbi request reprint Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    J Leukoc Biol 67:529-35. 2000
    ..These findings suggest that theophylline has an immunomodulatory action on neutrophil apoptosis via a mechanism of A2A antagonism...
  5. ncbi request reprint Presenility of granulocytes in Down syndrome individuals
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Am J Med Genet 84:406-12. 1999
    ....
  6. ncbi request reprint Effects of theophylline on human eosinophil functions: comparative study with neutrophil functions
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    J Leukoc Biol 68:194-200. 2000
    ..Theophylline thus modulates granulocyte functions in association with specific adenosine receptor antagonism and cAMP-PDE inhibition...
  7. pmc Pentoxifylline and CD14 antibody additively inhibit priming of polymorphonuclear leukocytes for enhanced release of superoxide by lipopolysaccharide: possible mechanism of these actions
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Infect Immun 62:922-7. 1994
    ..Clinical use of the antibody and POF may diminish tissue damage caused by PMN in clinical endotoxic shock...
  8. doi request reprint The effect of ascorbate on minor recurrent aphthous stomatitis
    K Yasui
    Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Acta Paediatr 99:442-5. 2010
    ..The purpose of this study was to evaluate the potential of ascorbate (vitamin C) to reduce the frequency of MRAS and severity of pain...
  9. pmc Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome
    K Agematsu
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto 390, Japan
    J Clin Invest 102:853-60. 1998
    ..However, the IgG production can be induced by stimulation of immunoglobulin receptors and CD40 in cooperation with such cytokines as IL-2 and IL-10 in vitro...
  10. ncbi request reprint New clinical applications of xanthine derivatives: modulatory actions on leukocyte survival and function
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Int J Hematol 73:87-92. 2001
    ..Here, we review some recent advances in the understanding of pharmacological actions and new applications of xanthine derivatives...
  11. ncbi request reprint Therapeutic potential of superoxide dismutase (SOD) for resolution of inflammation
    K Yasui
    Department of Pediatrics, Shinshu University School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    Inflamm Res 55:359-63. 2006
    ..If the drug can be delivered efficiently to the inflammatory site, SOD may be useful as an inhibitory mediator of neutrophil-mediated inflammation...
  12. pmc Multi-nucleated giant cell formation from human cord blood monocytes in vitro, in comparison with adult peripheral blood monocytes
    Y Kondo
    Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences 2 5 1 Shikata cho, Okayama, Japan
    Clin Exp Immunol 158:84-90. 2009
    ..0001). These results suggest the possibility that the susceptibility of newborns to mycobacterium infection is due partly to impaired MGC formation...
  13. ncbi request reprint Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation
    K Yasui
    Dept of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Eur Respir J 22:739-42. 2003
    ..The monitoring of urinary trypsin inhibitor concentrations might be useful for evaluating the neutrophil-mediated inflammation in childhood asthma attack...
  14. pmc Neutrophilic inflammation in childhood bronchial asthma
    K Yasui
    Thorax 60:704-5. 2005