Kazuyoshi Yamauchi

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. ncbi request reprint Internalization of beta-amyloid causes downregulation of apolipoprotein E mRNA expression in neuroblastoma cells
    Kazuyoshi Yamauchi
    Department of Laboratory Medicine, Shinshu University Hospital and Medical School, Asahi, Matsumoto, Japan
    Ann Clin Lab Sci 33:68-78. 2003
  2. doi request reprint A C-terminal amino acid substitution in the gamma-chain caused by a novel heterozygous frameshift mutation (Fibrinogen Matsumoto VII) results in hypofibrinogenaemia
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Thromb Haemost 104:213-23. 2010
  3. doi request reprint Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous cell-type mucin in gastric juice
    Seiko Kubota
    Department of Laboratory Medicine, Shinshu University Hospital, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Dig Dis Sci 56:3498-506. 2011
  4. doi request reprint In vitro transcription of compound heterozygous hypofibrinogenemia Matsumoto IX; first identification of FGB IVS6 deletion of 4 nucleotides and FGG IVS3-2A>G causing abnormal RNA splicing
    Fumiko Terasawa
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, 3 1 1 Asahi, Matsumoto, 390 8621, Japan
    Clin Chim Acta 411:1325-9. 2010
  5. ncbi request reprint In vitro expression of beta-thalassaemia gene (IVS1-1G>C) reveals complete inactivation of the normal 5' splice site and alternative aberrant RNA splicing
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Ann Clin Biochem 44:573-8. 2007
  6. ncbi request reprint A case of acute myelogenous leukemia with MLL-AF10 fusion caused by insertion of 5' MLL into 10p12, with concurrent 3' MLL deletion
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, 3 1 1 Asashi, Matsumoto, Japan
    Cancer Genet Cytogenet 171:24-30. 2006
  7. doi request reprint Phylogeny of a novel "Helicobacter heilmannii" organism from a Japanese patient with chronic gastritis based on DNA sequence analysis of 16S rRNA and urease genes
    Takehisa Matsumoto
    Department of Laboratory Medicine, Shinshu University Graduate School of Medicine, Asahi, Matsumoto, 390 8621, Japan
    J Microbiol 47:201-7. 2009
  8. pmc Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, Asahi, Matsumoto, Japan
    Scand J Gastroenterol 43:25-33. 2008
  9. doi request reprint Factor H gene variants in Japanese: its relation to atypical hemolytic uremic syndrome
    Saki Mukai
    Department of Laboratory Medicine, Shinshu University Hospital, Japan
    Mol Immunol 49:48-55. 2011
  10. ncbi request reprint [Functional analysis of heterozygous plasma dysfibrinogens derived from two families of gammaArg275Cys and three families of gammaArg275His, and haplotype analysis for these families]
    Yuka Kamijyo
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan
    Rinsho Byori 57:651-8. 2009

Collaborators

Detail Information

Publications46

  1. ncbi request reprint Internalization of beta-amyloid causes downregulation of apolipoprotein E mRNA expression in neuroblastoma cells
    Kazuyoshi Yamauchi
    Department of Laboratory Medicine, Shinshu University Hospital and Medical School, Asahi, Matsumoto, Japan
    Ann Clin Lab Sci 33:68-78. 2003
    ..A disorder of this physiological response could be linked to the development of AD...
  2. doi request reprint A C-terminal amino acid substitution in the gamma-chain caused by a novel heterozygous frameshift mutation (Fibrinogen Matsumoto VII) results in hypofibrinogenaemia
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Thromb Haemost 104:213-23. 2010
    ....
  3. doi request reprint Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous cell-type mucin in gastric juice
    Seiko Kubota
    Department of Laboratory Medicine, Shinshu University Hospital, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Dig Dis Sci 56:3498-506. 2011
    ..Recently, we presented an enzyme-linked immunosorbent assay (ELISA) method for measurement of GMC-type mucin in the gastric juice...
  4. doi request reprint In vitro transcription of compound heterozygous hypofibrinogenemia Matsumoto IX; first identification of FGB IVS6 deletion of 4 nucleotides and FGG IVS3-2A>G causing abnormal RNA splicing
    Fumiko Terasawa
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, 3 1 1 Asahi, Matsumoto, 390 8621, Japan
    Clin Chim Acta 411:1325-9. 2010
    ..To examine the transcription of mRNA from the M IX gene, we cloned the wild-type and mutant genes into expression vectors...
  5. ncbi request reprint In vitro expression of beta-thalassaemia gene (IVS1-1G>C) reveals complete inactivation of the normal 5' splice site and alternative aberrant RNA splicing
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Ann Clin Biochem 44:573-8. 2007
    ..Further studies will be required to clarify the molecular mechanism that results in severe reduction in the mutant mRNA level in vivo...
  6. ncbi request reprint A case of acute myelogenous leukemia with MLL-AF10 fusion caused by insertion of 5' MLL into 10p12, with concurrent 3' MLL deletion
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, 3 1 1 Asashi, Matsumoto, Japan
    Cancer Genet Cytogenet 171:24-30. 2006
    ..Our observations indicated that the MLL-AF10 fusion gene resulted from the insertion of part of the region that included the 5' MLL insertion into 10p12; this was concurrent with the deletion of 3' MLL...
  7. doi request reprint Phylogeny of a novel "Helicobacter heilmannii" organism from a Japanese patient with chronic gastritis based on DNA sequence analysis of 16S rRNA and urease genes
    Takehisa Matsumoto
    Department of Laboratory Medicine, Shinshu University Graduate School of Medicine, Asahi, Matsumoto, 390 8621, Japan
    J Microbiol 47:201-7. 2009
    ..Taxonomic analysis disclosed that SH6 represents a novel strain and should constitute a novel taxon in the phylogenetic trees, being discriminated from any other taxon, with the ability of infecting human gastric mucosa...
  8. pmc Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, Asahi, Matsumoto, Japan
    Scand J Gastroenterol 43:25-33. 2008
    ..To investigate the phenotypic characters of carcinoma cells and the response of gastric epithelial cells to Helicobacter pylori (H. pylori) infection using the gastric carcinoma cell lines...
  9. doi request reprint Factor H gene variants in Japanese: its relation to atypical hemolytic uremic syndrome
    Saki Mukai
    Department of Laboratory Medicine, Shinshu University Hospital, Japan
    Mol Immunol 49:48-55. 2011
    ..Our results suggested that although FH1 mutations relates to the development of Japanese aHUS in accordance with other ethnic studies, other factor may be required for factor H polymorphism to be a risk factor of Japanese aHUS...
  10. ncbi request reprint [Functional analysis of heterozygous plasma dysfibrinogens derived from two families of gammaArg275Cys and three families of gammaArg275His, and haplotype analysis for these families]
    Yuka Kamijyo
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan
    Rinsho Byori 57:651-8. 2009
    ..Furthermore haplotype analysis for three families with gammaArg275His suggested that founder of Iida family might be different from that of Otsu II or Shizuoka family...
  11. doi request reprint Quantitative monitoring of single nucleotide mutations by allele-specific quantitative PCR can be used for the assessment of minimal residual disease in patients with hematological malignancies throughout their clinical course
    Chiaki Taira
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto 390 8621, Japan
    Clin Chim Acta 412:53-8. 2011
    ..Single nucleotide mutations associated with leukemogenesis can be considered as applicable MRD markers...
  12. ncbi request reprint [Additional chromosomal changes in impaired chimeric analysis of a patient with relapsed leukemia after bone marrow transplantation]
    Yumiko Higuchi
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Rinsho Ketsueki 49:109-14. 2008
    ..As such, clinicians should consider the possibility that unexpected karyotype changes may invalidate PCR-STR analysis findings, especially when conflicting results appear among chimerism analyses...
  13. doi request reprint Specific, rapid, and sensitive enzymatic measurement of sphingomyelin, phosphatidylcholine and lysophosphatidylcholine in serum and lipid extracts
    Hiroya Hidaka
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine, Asahi 3 1 1, Matsumoto, Nagano, 390 8621, Japan
    Clin Biochem 41:1211-7. 2008
    ..However, there are no rapid and sensitive methods for SM and PC measurement. The present report describes a novel enzymatic method for measuring SM, PC and lysophosphatidylcholine (lyso-PC) levels in plasma and lipid extracts...
  14. ncbi request reprint [Analysis of antibody reactivity for FDP D-dimer fragments by Western blotting]
    Saki Wakabayashi
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Rinsho Byori 56:449-54. 2008
    ..Unfortunately, we did not directly demonstrate these phenomena by WB analysis with two anti-D-dimer antibodies used Nanopia or LPIA reagent. In the near future, we expect that standardization of FDP D-dimer assay will be accomplished...
  15. ncbi request reprint Sialic acid moiety of apolipoprotein E3 at Thr(194) affects its interaction with beta-amyloid(1-42) peptides
    Mitsutoshi Sugano
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Clin Chim Acta 388:123-9. 2008
    ..ApoE in cerebrospinal fluid is extensively sialylated, and sialylation of certain proteins are known to modulate biological function. We investigated the effects of a sialic acid moiety of apoE on the apoE-Abeta interaction...
  16. doi request reprint Analysis of plasmin generation and clot lysis of plasma fibrinogen purified from a heterozygous dysfibrinogenemia, BbetaGly15Cys (Hamamatsu II)
    Yuka Kamijyo
    Department of Laboratory Medicine, Shinshu University Hospital, Japan
    Blood Coagul Fibrinolysis 20:726-32. 2009
    ..Therefore, we did not clarify an association between the BbetaGly15Cys dysfibrinogenemia and arterial thrombosis...
  17. doi request reprint Recombinant variant fibrinogens substituted at residues gamma326Cys and gamma339Cys demonstrated markedly impaired secretion of assembled fibrinogen
    Ayumi Haneishi
    Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Japan
    Thromb Res 124:368-72. 2009
    ....
  18. ncbi request reprint Monitoring of hematopoietic chimerism by short tandem repeats, and the effect of CD selection on its sensitivity
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Clin Chem 50:2411-4. 2004
  19. ncbi request reprint Characterization of factor XII Tenri, a rare CRM-negative factor XII deficiency
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Ann Clin Lab Sci 34:218-25. 2004
    ....
  20. ncbi request reprint Degradation of pre-beta-high density lipoproteins and their binding activity to human blood monocytes
    Tetsuo Nakabayashi
    Department of Laboratory Medicine, School of Medicine, Shinshu University, Matsumoto, Nagano, Japan
    Ann Clin Lab Sci 34:287-98. 2004
    ..We suggest that limited proteolysis around amino acids 188-223 of apo A-I may affect lipid binding, which may in turn affect HDL structure and function...
  21. pmc Characterization of CIA-1, an Ambler class A extended-spectrum β-lactamase from Chryseobacterium indologenes
    Takehisa Matsumoto
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Antimicrob Agents Chemother 56:588-90. 2012
    ..bla(CIA-1)-like genes were detected from clinical isolates. In addition to the metallo-β-lactamase IND of Ambler class B, C. indologenes has a class A ESBL gene, bla(CIA-1), located on the chromosome...
  22. doi request reprint Sialic acid moiety of apolipoprotein E and its impact on the formation of lipoprotein particles in human cerebrospinal fluid
    Kenji Kawasaki
    Department of Laboratory Medicine, Shinshu University Hospital, Japan
    Clin Chim Acta 402:61-6. 2009
    ..The aim of the present study was to quantify the SA content in CSF apoE and carry out the more detailed characterization of the CSF apoE-containing lipoproteins...
  23. doi request reprint Simple polymerase chain reaction for the detection of mutations and deletions in the epidermal growth factor receptor gene: applications of this method for the diagnosis of non-small-cell lung cancer
    Miho Uhara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Clin Chim Acta 401:68-72. 2009
    ..Although various methods for detecting EGFR gene mutations have been developed, they have several disadvantages. We attempted to establish a new method for the detection of EGFR gene mutations with the use of paraffin-embedded samples...
  24. ncbi request reprint [Characterization of sialo-apolipoprotein E in human cerebrospinal fluid]
    Kazuyoshi Yamauchi
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto 390 8621, Japan
    Rinsho Byori 57:436-44. 2009
    ..The posttranslational modification of apoE, such as the presence of sialic acid moieties, may be involved in the regulation of lipid transport to the brain...
  25. ncbi request reprint [Analysis of hypofibrinogenemias found on routine coagulation screening tests and identification of heterozygous dysfibrinogenemia or fibrinogen deficiency]
    Masako Hirota-Kawadobora
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto
    Rinsho Byori 55:989-95. 2007
    ..These data and our previous reports suggest that heterozygous patients with dysfibrinogenemia or fibrinogen deficiency do not demonstrate markedly prolonged PT and APTT values, differing from patients with afibrinogenemia...
  26. ncbi request reprint A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia
    Eiko Hidaka
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Cancer Genet Cytogenet 176:137-43. 2007
    ..The NUP98-HOXD13 fusion transcript created by t(2;11;9)(q31;p15;q22) may play an important role in the leukemogenesis in this case...
  27. ncbi request reprint Characterization of triglyceride rich lipoproteins with very light density by ultracentrifugation and agarose gel electrophoresis using triglyceride- and cholesterol-staining
    Hiroya Hidaka
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Nagano, Japan
    Ann Clin Lab Sci 33:167-78. 2003
    ..In summary, a system using ultracentrifugation and agarose gel electrophoresis with triglyceride- and cholesterol-staining is useful for characterization of triglyceride rich lipoproteins and their remnants...
  28. ncbi request reprint Analysis of human serum lipoprotein lipid composition using MALDI-TOF mass spectrometry
    Hiroya Hidaka
    Department of Biomedical Laboratory Science, School of Health Sciences, Shinshu University, Asahi 3 1 1, Matsumoto, Nagano, Japan
    Ann Clin Lab Sci 37:213-21. 2007
    ..This study shows that MALDI-TOF MS can be used for direct investigation and quantitative analysis of the phospholipid composition of serum lipoproteins...
  29. ncbi request reprint Quantitative determination of gland mucous cells-type mucin using a monoclonal antibody, HIK1083: its pathophysiological changes in human gastric juice
    Seiko Kubota
    Department of Laboratory Medicine, Shinshu University Hospital, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Clin Chim Acta 377:261-7. 2007
    ..pylori infection, is critical in the pathogenesis of H. pylori-related gastritis. We established an assay for GMCs-type mucin and quantitatively assessed the pathophysiological changes in its content in human gastric juice samples...
  30. doi request reprint Cryptic insertion into 11q23 of MLLT10 not involved in t(1;15;11;10)(p36;q11;q23;q24) in infant acute biphenotypic leukemia
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Cancer Genet Cytogenet 190:113-20. 2009
    ..Furthermore, the level of MRD had already increased before hematologic relapse. The identification and characterization of MLL rearrangement at the genomic DNA level may be useful for MRD quantification...
  31. doi request reprint Laboratory appraisal of optimal gaseous conditions for growth of zoonotic Helicobacter felis ATCC 49179
    Mayumi Shiohara
    Department of Laboratory Medicine, Shinshu University Graduate School of Medicine, Matsumoto, Japan
    Microbiol Immunol 53:251-8. 2009
    ..In culturing H. felis strains, optimal gaseous conditions should be employed according to the purposes or preferences of study designs...
  32. ncbi request reprint Novel beta-thalassemia trait (IVS I-1 G-->C) in a Japanese family
    Noriko Fujihara
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Am J Hematol 72:64-6. 2003
    ....
  33. ncbi request reprint Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells
    Kazuyoshi Yamauchi
    Central Clinical Laboratories, Shinshu University Hospital, Matsumoto, Japan
    Ann Clin Lab Sci 32:65-74. 2002
    ..The isoform-specific effects of apoE on the endocytosis of Abeta may be implicated in the development of Alzheimer's disease, and if so, each isoform of apoE would induce a different incidence of that disease...
  34. ncbi request reprint [Clinical assessment of novel ChromID ESBL agar plates for detection of ESBL producers in the family Enterobacteriaceae]
    Eriko Kasuga
    Department of Laboratory Medicine, Shinshu University Hospital, and Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine
    Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 20:1-8. 2009
    ....
  35. ncbi request reprint A novel variant fibrinogen, deletion of Bbeta111Ser in coiled-coil region, affecting fibrin lateral aggregation
    Nobuo Okumura
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, Japan
    Clin Chim Acta 365:160-7. 2006
    ..Functional fibrinogen concentration of a male infant showed <0.50 g/l and we speculated this patient as a dysfibrinogenemia or hypofibrinogenemia...
  36. ncbi request reprint [Crucial roles of Helicobacter pylori infection in the pathogenesis of gastric cancer and gastric mucosa-associated lymphoid tissue (MALT) lymphoma]
    Hiroyoshi Ota
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Rinsho Byori 57:861-9. 2009
    ..the nuclear factor-kappaB pathway. This paper reviews recent advances in our understanding of the association of H. pylori infection with gastric cancer and gastric MALT lymphoma and the molecular genetics underlying tumor development...
  37. ncbi request reprint New enzymatic assay using phospholipase D to measure total calcium in serum
    Mitsutoshi Sugano
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Clin Chem 51:1021-4. 2005
  38. ncbi request reprint Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells
    Hiroya Hidaka
    Shinshu University School of Health Sciences, Matsumoto, Nagano, Japan
    Ann Clin Lab Sci 33:271-8. 2003
    ..The present study of HDL-binding proteins in mononuclear cells advances our understanding of the physiological roles and fate of HDL...
  39. ncbi request reprint DNA microarray analysis of T cell-type lymphoproliferative disease of granular lymphocytes
    Hideki Makishima
    Second Department of Internal Medicine, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Br J Haematol 118:462-9. 2002
    ..These data have shown that microarray analysis with a purified T-cell subset is an efficient approach to investigate the pathological condition of Tcell-type LDGL...
  40. ncbi request reprint An immunoglobulin A1 that inhibits lactate dehydrogenase activity, with reversal of inhibition by addition of NADH
    Kiyotaka Fujita
    Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, 3 1 1 Asahi, Matsumoto, Nagano, Japan
    Ann Clin Lab Sci 36:461-8. 2006
    ..Moreover, the possibility exists that part of the patient's IgA1 molecule fits into a pocket of LD in instead of NADH. This is the first report of NADH reversing such LD inhibition...
  41. ncbi request reprint Trefoil factor 2 in gland mucous cell mucin in the mucous gel covering normal or damaged gastric mucosa using the Mongolian gerbil model
    Kazufumi Suzuki
    Department of Surgery, School of Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Scand J Gastroenterol 41:1390-7. 2006
    ....
  42. ncbi request reprint t(8;21;14)(q22;q22;q24) is a novel variant of t(8;21) with chimeric transcripts of AML1-ETO in acute myelogenous leukemia
    Fumihiro Ishida
    Second Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan
    Cancer Genet Cytogenet 132:133-5. 2002
    ..Translocation (8;21;14)(q22;q22;q24) is a novel variant of t(8;21)(q22;q22), possibly having a common molecular pathogenetic mechanism...
  43. ncbi request reprint Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
    Kazuyuki Matsuda
    Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
    Blood 109:5477-80. 2007
    ..Additionally, numbers of circulating granulocyte-macrophage progenitors were significantly reduced during the clinical course. Thus, some patients with JMML with specific RAS mutations may have spontaneously improving disease...
  44. ncbi request reprint Quantitative RT-PCR analysis demonstrates that synthesis of the recombinant fibrinogen is dependent on the transcription and synthesis of gamma-chain
    Masako Hirota-Kawadobora
    Central Clinical Laboratory, Shinshu University Hospital, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Clin Chim Acta 319:67-73. 2002
    ..The purpose of this study was to examine the relationship between the production of secreted fibrinogen and the synthesis of gamma-chain mRNA...
  45. ncbi request reprint Analysis of fibrinogen variants at gamma387Ile shows that the side chain of gamma387 and the tertiary structure of the gammaC-terminal tail are important not only for assembly and secretion of fibrinogen but also for lateral aggregation of protofibrils an
    Satomi Kani
    Laboratory of Clinical Chemistry, Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Blood 108:1887-94. 2006
    ..Interestingly, our results clearly indicate that the conformations critical for these 2 functions are different from each other...
  46. ncbi request reprint Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
    Satoshi Ishizone
    Department of Surgery, Shinshu University School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    Cancer Sci 97:119-26. 2006
    ..These results suggest that quantitative analysis of alpha4GnT mRNA expressed in the mononuclear cell fraction of peripheral blood will contribute to the detection of pancreatic cancer...