Satoru Suzuki

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. doi request reprint Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance
    S Suzuki
    Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Shinshu University School of Medicine, Nagano, Japan
    Horm Metab Res 45:501-6. 2013
  2. doi request reprint Availability of self-recorded axillary temperature for assessment of thermic effects of food: relationship between HDL-cholesterol level and postprandial thermoregulation in type 2 diabetic patients
    S Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Japan
    Exp Clin Endocrinol Diabetes 120:96-100. 2012
  3. ncbi request reprint Spiking expression of mu-crystallin mRNA during treatment with methimazole in patients with graves' hyperthyroidism
    S Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Matsumoto, Japan
    Horm Metab Res 41:548-53. 2009
  4. doi request reprint Pituitary resistance to thyroid hormones: pathophysiology and therapeutic options
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
    Endocrine 40:366-71. 2011
  5. pmc Gender-specific regulation of response to thyroid hormone in aging
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
    Thyroid Res 5:1. 2012
  6. ncbi request reprint Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1
    Ako Oiwa
    Shinshu University Graduate School of Medicine, Institute on Aging and Adaptation, Department of Aging Medicine and Geriatrics, Matsumoto 390 8621, Japan
    Biochem Biophys Res Commun 353:895-901. 2007
  7. ncbi request reprint Cell-specific expression of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein (p38CTBP)
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
    Eur J Endocrinol 148:259-68. 2003
  8. ncbi request reprint micro-Crystallin as an intracellular 3,5,3'-triiodothyronine holder in vivo
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
    Mol Endocrinol 21:885-94. 2007
  9. ncbi request reprint Expression of thyroid hormone receptor alpha in 3T3-L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulation
    Wei Jiang
    Department of Aging Medicine and Geriatrics, Institute of Aging and Adaptation, Shinshu University Graduate School, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    J Endocrinol 182:295-302. 2004
  10. ncbi request reprint Administration of recombinant human growth hormone normalizes GH-IGF1 axis and improves malnutrition-related disorders in patients with anorexia nervosa
    Kiyoshi Hashizume
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Japan
    Endocr J 54:319-27. 2007

Collaborators

Detail Information

Publications33

  1. doi request reprint Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance
    S Suzuki
    Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Shinshu University School of Medicine, Nagano, Japan
    Horm Metab Res 45:501-6. 2013
    ..The expression of μ-crystallin was regulated through the AP-1 site in the promoter. The signals related to AP-1 activation, such as insulin signaling may have diverse effects on μ-crystallin mRNA expression. ..
  2. doi request reprint Availability of self-recorded axillary temperature for assessment of thermic effects of food: relationship between HDL-cholesterol level and postprandial thermoregulation in type 2 diabetic patients
    S Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Japan
    Exp Clin Endocrinol Diabetes 120:96-100. 2012
    ..The present study was performed to develop a simple procedure for assessment of body temperature and to determine whether postprandial thermoregulation is related to metabolic regulation in diabetic patients...
  3. ncbi request reprint Spiking expression of mu-crystallin mRNA during treatment with methimazole in patients with graves' hyperthyroidism
    S Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Matsumoto, Japan
    Horm Metab Res 41:548-53. 2009
    ..Thyroid hormone-regulated mu-crystallin expression may control thyroid hormone action via the intracytoplasmic T (3) capacity...
  4. doi request reprint Pituitary resistance to thyroid hormones: pathophysiology and therapeutic options
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
    Endocrine 40:366-71. 2011
    ....
  5. pmc Gender-specific regulation of response to thyroid hormone in aging
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
    Thyroid Res 5:1. 2012
    ..abstract:..
  6. ncbi request reprint Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1
    Ako Oiwa
    Shinshu University Graduate School of Medicine, Institute on Aging and Adaptation, Department of Aging Medicine and Geriatrics, Matsumoto 390 8621, Japan
    Biochem Biophys Res Commun 353:895-901. 2007
    ..The cyclic expression of mSHP may affect daily activity of other nuclear receptors and contribute to circadian liver functions...
  7. ncbi request reprint Cell-specific expression of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein (p38CTBP)
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
    Eur J Endocrinol 148:259-68. 2003
    ..The evidence for the presence of tIssue-specific localization of p38CTBP has indicated that p38CTBP has a tIssue-specific function, such as the regulation of T3 delivery from cytoplasm to nuclei...
  8. ncbi request reprint micro-Crystallin as an intracellular 3,5,3'-triiodothyronine holder in vivo
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
    Mol Endocrinol 21:885-94. 2007
    ..These data suggest that because of rapid T(3) turnover, disruption of the CRYM gene decreases T(3) concentrations in tissues and serum without alteration of peripheral T(3) action in vivo...
  9. ncbi request reprint Expression of thyroid hormone receptor alpha in 3T3-L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulation
    Wei Jiang
    Department of Aging Medicine and Geriatrics, Institute of Aging and Adaptation, Shinshu University Graduate School, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    J Endocrinol 182:295-302. 2004
    ..We conclude that the TRalpha isoform might play an important role in the generation and maintenance of the mature adipocyte phenotype, regulating the expression of lipogenic enzymes...
  10. ncbi request reprint Administration of recombinant human growth hormone normalizes GH-IGF1 axis and improves malnutrition-related disorders in patients with anorexia nervosa
    Kiyoshi Hashizume
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Japan
    Endocr J 54:319-27. 2007
    ..These improvements were not observed in patients treated with placebo. Administration of rhGH is recommended as one of the methods of managing the patients with AN...
  11. ncbi request reprint Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter
    Teiji Takeda
    Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School, Matsumoto, Nagano 390 8621, Japan
    J Clin Endocrinol Metab 88:3531-8. 2003
    ..These results indicate that the AdhTERTtk/GCV system is a promising therapy for undifferentiated thyroid carcinoma, which is one of the most malignant tumors, without damage to normal tissues...
  12. doi request reprint {mu}-Crystallin, new candidate protein in endotoxin-induced uveitis
    Hiroki Imai
    Departments of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan
    Invest Ophthalmol Vis Sci 51:3554-9. 2010
    ..Expression of the mRNA of IL-1alpha and -6 in the CRYM(-/-) mice was significantly lower than that in the CRYM(+/+) mice on day 5. CONCLUSIONS. CRYM plays an important role in the development of the second peak of murine EIU...
  13. doi request reprint Lymphocytic infundibuloneurohypophysitis: long-term follow-up of a case cured with glucocorticoid
    Hidefumi Inaba
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Med Princ Pract 19:79-81. 2010
    ..To report a case of infundibuloneurohypophysitis treated with steroid...
  14. ncbi request reprint mu-crystallin, a NADPH-dependent T(3)-binding protein in cytosol
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Trends Endocrinol Metab 18:286-9. 2007
    ..Cytosolic thyroid hormone-binding proteins, especially mu-crystallin, have roles in adaptation to environmental alterations by thyroid hormone, which might have a role in hearing function...
  15. doi request reprint Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report
    Hidefumi Inaba
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Med Princ Pract 21:190-2. 2012
    ..To report a case of amiodarone-induced thyrotoxicosis (AIT) concomitant with thyroid cancer in multinodular goiter (MNG)...
  16. ncbi request reprint Cytosolic T3-binding protein modulates dynamic alteration of T3-mediated gene expression in cells
    Keiko Takeshige
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Endocr J 61:561-70. 2014
    ..The heterogeneity of T3-related gene expression is dependent on cellular CRYM expression in cases of dynamic changes in pericellular T3 concentration. ..
  17. ncbi request reprint The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells
    Takeshi Inagaki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Division of Medicine, Shinshu University Graduate School, 3 1 1, Asahi, Matsumoto 390 8621, Japan
    J Biol Chem 278:51685-92. 2003
    ..These data suggest that ATRA-inducible RARP1 selectively affects signal transduction and may contribute to myeloid and megakaryocytic differentiation...
  18. ncbi request reprint A kindred with Cockayne syndrome caused by multiple splicing variants of the CSA gene
    Ai Komatsu
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Division of Medicine, Shinshu University Graduate School, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Am J Med Genet A 128:67-71. 2004
    ..These data suggest that multiple splicing variant forms of CSA mRNA, in the absence of the full-length form of the mRNA, are associated with CS...
  19. ncbi request reprint A somatotropin-producing pituitary adenoma with an isolated adrenocorticotropin-producing pituitary adenoma in a female patient with acromegaly, subclinical Cushing's disease and a left adrenal tumor
    Yuki Kobayashi
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Endocr J 61:589-95. 2014
    ..This is a rare case of independent double pituitary adenomas with distinct hormonal features. We also provide a review of the previously reported cases of double pituitary adenomas and discuss the etiology of these tumors. ..
  20. ncbi request reprint Occurrence of IgG4-related hypophysitis lacking IgG4-bearing plasma cell infiltration during steroid therapy
    Yohsuke Ohkubo
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Shinshu University School of Medicine, Japan
    Intern Med 53:753-7. 2014
    ..Based on a review of the diagnosis, conducting a careful assessment is required, especially in men and elderly patients thought to have solitary hypophysitis. ..
  21. ncbi request reprint A new experimental model of ATP-sensitive K⁺ channel-independent insulinotropic action of glucose: a permissive role of cAMP for triggering of insulin release from rat pancreatic β-cells
    Masahiro Takei
    Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Endocr J 60:599-607. 2013
    ..Cerulenin, an inhibitor of protein acylation, decreased the glucose effect. In conclusion, a rise in [Ca²⁺]i through voltage-dependent Ca²⁺ channels is not mandatory for glucose-induced triggering of insulin release...
  22. ncbi request reprint Humoral hypercalcemia associated with gastric carcinoma secreting parathyroid hormone: a case report and review of the literature
    Koji Nakajima
    Department of Internal Medicine, Iida Municipal Hospital, Iida 395 8502, Japan
    Endocr J 60:557-62. 2013
    ..To our knowledge, this is the first case report of PTH-secreting gastric carcinoma cells. We report the case and a review of the previous reported PTH-secreting non-parathyroid tumors along with the mechanisms of secretion...
  23. doi request reprint A case of severe and recurrent painless thyroiditis requiring thyroidectomy
    Hiroaki Ishii
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Med Princ Pract 22:408-10. 2013
    ..To report a case of severe and recurrent painless thyroiditis requiring thyroidectomy...
  24. ncbi request reprint A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas
    Teiji Takeda
    Department of Aging Medicine and Geriatrics, Shinshu University, School of Medicine, Matsumoto, Nagano, Japan
    Cancer Gene Ther 9:864-74. 2002
    ..These data indicate a beneficial effect of Ad2 x TGtk for tissue-specific gene therapy for TG-producing thyroid carcinomas without toxicity for normal tissues...
  25. ncbi request reprint Inhibition of peroxisome proliferator-activated receptor alpha signaling by vitamin D receptor
    Takahiro Sakuma
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 390 8621, Matsumoto, Japan
    Biochem Biophys Res Commun 312:513-9. 2003
    ..VDR signaling might be considered as a factor regulating lipid metabolism via PPARalpha pathway. We report here the novel action of VDR in controlling gene expression through PPARalpha signaling...
  26. ncbi request reprint Metabolic syndrome and age-related dementia: endocrinological aspects of adaptation to aging
    Kiyoshi Hashizume
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Japan
    Mech Ageing Dev 127:507-10. 2006
    ..In this review, we summarize our clinical and experimental data, and discuss on the mechanism of the metabolic syndrome prevention of progression of age-related mental disorder...
  27. ncbi request reprint [Multiple endocrine neoplasia type IIa (MEN2A)]
    Kiyoshi Hashizume
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine
    Nihon Rinsho . 2006
  28. ncbi request reprint Leydig cell tumor and malignant lymphoma in a patient with nonclassical 21-hydroxylase deficiency
    Hidefumi Inaba
    Department of Aging and Geriatrics, Shinshu University, Matsumoto, Japan
    Intern Med 48:601-5. 2009
    ..The genetic background of 21-OHD might contribute to the development of malignant lymphoma. Such as a case of LCT and malignant lymphoma in a patient with 21-OHD seems to be rare...
  29. ncbi request reprint Spontaneous remission of diabetes insipidus due to CNS sarcoidosis
    Hidefumi Inaba
    Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine, Matsumoto
    Intern Med 48:225-9. 2009
    ..However, CDI and pituitary MRI findings were getting recovered spontaneously without steroid treatment in a couple of months, suggesting an atypical clinical course of CNS sarcoidosis...
  30. ncbi request reprint Nicotinamide adenine dinucleotide phosphate-dependent cytosolic T(3) binding protein as a regulator for T(3)-mediated transactivation
    Jun Ichirou Mori
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
    Endocrinology 143:1538-44. 2002
    ....
  31. ncbi request reprint Beneficial effects of pioglitazone on cholangiohepatitis induced by bile duct carcinoma
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Matsumoto
    Intern Med 46:1723-7. 2007
    ..Although he finally died of obstructive jaundice, thiazolidinedione should be considered for treatment of tumor-induced hepatitis in the presence of diabetes, unless severe side effects occur...
  32. ncbi request reprint Fulminant diabetes mellitus associated with pregnancy: case reports and literature review
    Takeshi Inagaki
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Endocr J 49:319-22. 2002
    ..Our present finding suggests that this type of fulminant type 1 diabetes mellitus associated with pregnancy might develop as a consequence of a nonautoimmune mechanism...
  33. pmc Do PPARgamma Ligands Suppress the Growth of Cholangiocarcinoma or the Cholangiohepatitis Induced by the Tumor?
    Satoru Suzuki
    Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    PPAR Res 2008:587401. 2008
    ..Thiazolidinedione should be considered for management of tumor-induced hepatitis in the presence of diabetes unless severe side effects occur...