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Genomes and Genes | Satoru SuzukiSummaryAffiliation: Shinshu University Country: Japan Publications
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Publications
Availability of self-recorded axillary temperature for assessment of thermic effects of food: relationship between HDL-cholesterol level and postprandial thermoregulation in type 2 diabetic patientsS Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Japan
Exp Clin Endocrinol Diabetes 120:96-100. 2012..The present study was performed to develop a simple procedure for assessment of body temperature and to determine whether postprandial thermoregulation is related to metabolic regulation in diabetic patients...
Gender-specific regulation of response to thyroid hormone in agingSatoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
Thyroid Res 5:1. 2012..abstract:..
Spiking expression of mu-crystallin mRNA during treatment with methimazole in patients with graves' hyperthyroidismS Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Matsumoto, Japan
Horm Metab Res 41:548-53. 2009..Thyroid hormone-regulated mu-crystallin expression may control thyroid hormone action via the intracytoplasmic T (3) capacity...
Pituitary resistance to thyroid hormones: pathophysiology and therapeutic optionsSatoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
Endocrine 40:366-71. 2011....
Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1Ako Oiwa
Shinshu University Graduate School of Medicine, Institute on Aging and Adaptation, Department of Aging Medicine and Geriatrics, Matsumoto 390 8621, Japan
Biochem Biophys Res Commun 353:895-901. 2007..The cyclic expression of mSHP may affect daily activity of other nuclear receptors and contribute to circadian liver functions...
Cell-specific expression of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein (p38CTBP)Satoru Suzuki
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
Eur J Endocrinol 148:259-68. 2003..The evidence for the presence of tIssue-specific localization of p38CTBP has indicated that p38CTBP has a tIssue-specific function, such as the regulation of T3 delivery from cytoplasm to nuclei...
micro-Crystallin as an intracellular 3,5,3'-triiodothyronine holder in vivoSatoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1, Asahi, Matsumoto, Nagano 390 8621, Japan
Mol Endocrinol 21:885-94. 2007..These data suggest that because of rapid T(3) turnover, disruption of the CRYM gene decreases T(3) concentrations in tissues and serum without alteration of peripheral T(3) action in vivo...
Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoterTeiji Takeda
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School, Matsumoto, Nagano 390 8621, Japan
J Clin Endocrinol Metab 88:3531-8. 2003..These results indicate that the AdhTERTtk/GCV system is a promising therapy for undifferentiated thyroid carcinoma, which is one of the most malignant tumors, without damage to normal tissues...
Expression of thyroid hormone receptor alpha in 3T3-L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulationWei Jiang
Department of Aging Medicine and Geriatrics, Institute of Aging and Adaptation, Shinshu University Graduate School, 3-1-1 Asahi, Matsumoto 390-8621, Japan
J Endocrinol 182:295-302. 2004..We conclude that the TRalpha isoform might play an important role in the generation and maintenance of the mature adipocyte phenotype, regulating the expression of lipogenic enzymes...
Administration of recombinant human growth hormone normalizes GH-IGF1 axis and improves malnutrition-related disorders in patients with anorexia nervosaKiyoshi Hashizume
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Japan
Endocr J 54:319-27. 2007..These improvements were not observed in patients treated with placebo. Administration of rhGH is recommended as one of the methods of managing the patients with AN...
mu-crystallin, a NADPH-dependent T(3)-binding protein in cytosolSatoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
Trends Endocrinol Metab 18:286-9. 2007..Cytosolic thyroid hormone-binding proteins, especially mu-crystallin, have roles in adaptation to environmental alterations by thyroid hormone, which might have a role in hearing function...
{mu}-Crystallin, new candidate protein in endotoxin-induced uveitisHiroki Imai
Departments of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan
Invest Ophthalmol Vis Sci 51:3554-9. 2010..Expression of the mRNA of IL-1alpha and -6 in the CRYM(-/-) mice was significantly lower than that in the CRYM(+/+) mice on day 5. CONCLUSIONS. CRYM plays an important role in the development of the second peak of murine EIU...
Lymphocytic infundibuloneurohypophysitis: long-term follow-up of a case cured with glucocorticoidHidefumi Inaba
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan
Med Princ Pract 19:79-81. 2010..To report a case of infundibuloneurohypophysitis treated with steroid...
Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case reportHidefumi Inaba
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan
Med Princ Pract 21:190-2. 2012..To report a case of amiodarone-induced thyrotoxicosis (AIT) concomitant with thyroid cancer in multinodular goiter (MNG)...
The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cellsTakeshi Inagaki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Division of Medicine, Shinshu University Graduate School, 3 1 1, Asahi, Matsumoto 390 8621, Japan
J Biol Chem 278:51685-92. 2003..These data suggest that ATRA-inducible RARP1 selectively affects signal transduction and may contribute to myeloid and megakaryocytic differentiation...
A kindred with Cockayne syndrome caused by multiple splicing variants of the CSA geneAi Komatsu
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Division of Medicine, Shinshu University Graduate School, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
Am J Med Genet A 128:67-71. 2004..These data suggest that multiple splicing variant forms of CSA mRNA, in the absence of the full-length form of the mRNA, are associated with CS...
A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomasTeiji Takeda
Department of Aging Medicine and Geriatrics, Shinshu University, School of Medicine, Matsumoto, Nagano, Japan
Cancer Gene Ther 9:864-74. 2002..These data indicate a beneficial effect of Ad2 x TGtk for tissue-specific gene therapy for TG-producing thyroid carcinomas without toxicity for normal tissues...
Leydig cell tumor and malignant lymphoma in a patient with nonclassical 21-hydroxylase deficiencyHidefumi Inaba
Department of Aging and Geriatrics, Shinshu University, Matsumoto, Japan
Intern Med 48:601-5. 2009..The genetic background of 21-OHD might contribute to the development of malignant lymphoma. Such as a case of LCT and malignant lymphoma in a patient with 21-OHD seems to be rare...
[Multiple endocrine neoplasia type IIa (MEN2A)]Kiyoshi Hashizume
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine
Nippon Rinsho . 2006
Spontaneous remission of diabetes insipidus due to CNS sarcoidosisHidefumi Inaba
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine, Matsumoto
Intern Med 48:225-9. 2009..However, CDI and pituitary MRI findings were getting recovered spontaneously without steroid treatment in a couple of months, suggesting an atypical clinical course of CNS sarcoidosis...
Beneficial effects of pioglitazone on cholangiohepatitis induced by bile duct carcinomaSatoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Matsumoto
Intern Med 46:1723-7. 2007..Although he finally died of obstructive jaundice, thiazolidinedione should be considered for treatment of tumor-induced hepatitis in the presence of diabetes, unless severe side effects occur...
Inhibition of peroxisome proliferator-activated receptor alpha signaling by vitamin D receptorTakahiro Sakuma
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 390-8621, Matsumoto, Japan
Biochem Biophys Res Commun 312:513-9. 2003..VDR signaling might be considered as a factor regulating lipid metabolism via PPARalpha pathway. We report here the novel action of VDR in controlling gene expression through PPARalpha signaling...
Metabolic syndrome and age-related dementia: endocrinological aspects of adaptation to agingKiyoshi Hashizume
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University, Graduate School of Medicine, Japan
Mech Ageing Dev 127:507-10. 2006..In this review, we summarize our clinical and experimental data, and discuss on the mechanism of the metabolic syndrome prevention of progression of age-related mental disorder...
Fulminant diabetes mellitus associated with pregnancy: case reports and literature reviewTakeshi Inagaki
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
Endocr J 49:319-22. 2002..Our present finding suggests that this type of fulminant type 1 diabetes mellitus associated with pregnancy might develop as a consequence of a nonautoimmune mechanism...
Do PPARgamma Ligands Suppress the Growth of Cholangiocarcinoma or the Cholangiohepatitis Induced by the Tumor?Satoru Suzuki
Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
PPAR Res 2008:587401. 2008..Thiazolidinedione should be considered for management of tumor-induced hepatitis in the presence of diabetes unless severe side effects occur...
Nicotinamide adenine dinucleotide phosphate-dependent cytosolic T(3) binding protein as a regulator for T(3)-mediated transactivationJun Ichirou Mori
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto, 390 8621, Japan
Endocrinology 143:1538-44. 2002....
