Masato Ikeda

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. ncbi Elucidation of genes relevant to the microaerobic growth of Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Biosci Biotechnol Biochem 73:2806-8. 2009
  2. ncbi Amino acid production processes
    Masato Ikeda
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, 3 6 6, Asahi machi, Machida, Tokyo 194 8533, Japan
    Adv Biochem Eng Biotechnol 79:1-35. 2003
  3. ncbi Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 69:615-26. 2006
  4. ncbi Sugar transport systems in Corynebacterium glutamicum: features and applications to strain development
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 96:1191-200. 2012
  5. ncbi Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Microbiol Biotechnol 90:1443-51. 2011
  6. ncbi A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, 399 4598, Nagano, Japan
    J Ind Microbiol Biotechnol 33:610-5. 2006
  7. ncbi Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Appl Environ Microbiol 76:7154-60. 2010
  8. ncbi The Cgl1281-encoding putative transporter of the cation diffusion facilitator family is responsible for alkali-tolerance in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Arch Microbiol 190:531-8. 2008
  9. ncbi Anaerobic growth and potential for amino acid production by nitrate respiration in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 75:1173-82. 2007
  10. ncbi Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer
    Masato Ikeda
    BioProcess Development Center, Kyowa Hakko Bio Co, Ltd, Tsukuba, Ibaraki 305 0841, Japan m
    Appl Environ Microbiol 75:1635-41. 2009

Collaborators

  • Hiroshi Mizoguchi
  • Mikiro Hayashi
  • Seiki Takeno
  • Junko Ohnishi
  • Satoshi Mitsuhashi
  • Shinji Matsumoto
  • Sung Jean Park
  • Richard Longnecker
  • Peter Speck
  • Nobuyoshi Tsukamoto
  • Daisuke Shirakura
  • Ryosuke Kobayashi
  • Ryosuke Murata
  • Itaru Hamachi
  • Hiroyuki Aoki
  • Kazuhito V Tabata
  • Satoshi Yamaguchi
  • Shiori Ueno
  • Koji Ishizuka
  • Hiroyuki Noji
  • Rie Fukai
  • Yuko Iko
  • Shinzaburo Ito
  • Harunobu Komatsu
  • Mio Nakamura
  • Tomoha Komatsu
  • Tatsuya Masaki
  • Kikuo Sen
  • Suk Kyeong Lee
  • Ritsuko Katahira
  • Min-Duk Seo
  • Bong Jin Lee
  • Shingo Kakita
  • Akiko Ikeda
  • Howard M Lederman

Detail Information

Publications20

  1. ncbi Elucidation of genes relevant to the microaerobic growth of Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Biosci Biotechnol Biochem 73:2806-8. 2009
    ..Some of these genes showed cross-complementation of the mutants in oxygen-limiting static culture, suggesting the utility of these genes for improved growth and production under oxygen limitation...
  2. ncbi Amino acid production processes
    Masato Ikeda
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, 3 6 6, Asahi machi, Machida, Tokyo 194 8533, Japan
    Adv Biochem Eng Biotechnol 79:1-35. 2003
    ..Furthermore, the rapid strides in genome analysis are bound to revolutionize the strain improvement methodology...
  3. ncbi Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 69:615-26. 2006
    ....
  4. ncbi Sugar transport systems in Corynebacterium glutamicum: features and applications to strain development
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 96:1191-200. 2012
    ..glutamicum strains that express non-PTS routes instead of the original PTS. The potential practical advantages of the development of such strains are discussed...
  5. ncbi Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Microbiol Biotechnol 90:1443-51. 2011
    ..When this strategy was applied to a defined lysine producer, the engineered strain displayed increased lysine production from glucose...
  6. ncbi A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, 399 4598, Nagano, Japan
    J Ind Microbiol Biotechnol 33:610-5. 2006
    ..Here we describe the essence of our approach for strain reconstruction, and also discuss mechanisms of L-lysine hyperproduction unraveled by combining genomics with classical strain improvement...
  7. ncbi Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Appl Environ Microbiol 76:7154-60. 2010
    ..These results demonstrate effective l-lysine production by C. glutamicum with an additional source of NADPH during glycolysis...
  8. ncbi The Cgl1281-encoding putative transporter of the cation diffusion facilitator family is responsible for alkali-tolerance in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Arch Microbiol 190:531-8. 2008
    ..These results demonstrated that the putative transporter of the CDF family mediates resistance to cobalt and also plays a physiological role in alkaline pH tolerance in C. glutamicum...
  9. ncbi Anaerobic growth and potential for amino acid production by nitrate respiration in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 75:1173-82. 2007
    ..Agar piece assays using L-lysine- and L-arginine-producing strains showed that production of both amino acids occurred anaerobically by nitrate respiration, indicating the potential of C. glutamicum for anaerobic amino acid production...
  10. ncbi Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer
    Masato Ikeda
    BioProcess Development Center, Kyowa Hakko Bio Co, Ltd, Tsukuba, Ibaraki 305 0841, Japan m
    Appl Environ Microbiol 75:1635-41. 2009
    ..coli argB. This reconstructed strain displayed an enhanced performance, thus allowing significantly higher productivity of arginine/citrulline even at the suboptimal 38 degrees C...
  11. ncbi Significance of the Cgl1427 gene encoding cytidylate kinase in microaerobic growth of Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 97:1259-67. 2013
    ..These results indicate that CMP kinase plays an important role in normal nucleotide biosynthesis under an oxygen-limiting environment...
  12. ncbi A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum
    Junko Ohnishi
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, Asahi-machi, Machida, Tokyo 194-8533, Japan
    FEMS Microbiol Lett 242:265-74. 2005
    ....
  13. ncbi A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum
    Mikiro Hayashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Machida, Tokyo 194-8533, Japan
    Appl Microbiol Biotechnol 72:783-9. 2006
    ..Transcriptome analysis revealed that many amino acid biosynthetic genes, including lysC-asd operon, were significantly upregulated in the leuC mutant in a rel-independent manner...
  14. ncbi Characterization of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain
    Junko Ohnishi
    Bio Frontier Laboratories, Kyowa Hakko Kogyo Co Ltd, Machida, Tokyo, Japan
    Mutat Res 649:239-44. 2008
    ....
  15. ncbi Transcriptome analysis reveals global expression changes in an industrial L-lysine producer of Corynebacterium glutamicum
    Mikiro Hayashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Tokyo, Japan
    Biosci Biotechnol Biochem 70:546-50. 2006
    ..These results suggest that a certain global regulatory mechanism is involved in the industrial levels of L-lysine production...
  16. ncbi Photo gel-sol/sol-gel transition and its patterning of a supramolecular hydrogel as stimuli-responsive biomaterials
    Shinji Matsumoto
    Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Nishikyo ku, Kyoto, 615 8510, Japan
    Chemistry 14:3977-86. 2008
    ..These results demonstrated that the photoresponsive supramolecular hydrogel and the resulting nanomeshes may provide unique biomaterials for the spatiotemporal manipulation of various biomolecules and live bacteria...
  17. ncbi Expression and characterization of N-terminal domain of Epstein-Barr virus latent membrane protein 2A in Escherichia coli
    Sung Jean Park
    National Research Laboratory (MPS, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, San 56-1, Shillim-dong, Kwanak-Gu, Seoul 151-742, Republic of Korea
    Protein Expr Purif 41:9-17. 2005
    ....
  18. ncbi Comparisons of potentials for L-lysine production among different Corynebacterium glutamicum strains
    Junko Ohnishi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Tokyo, Japan
    Biosci Biotechnol Biochem 70:1017-20. 2006
    ..These results indicate the diversity among C. glutamicum strains in fermentative characters, as well as the importance of selecting a strain with industrially best performance...
  19. ncbi Disruption of malate:quinone oxidoreductase increases L-lysine production by Corynebacterium glutamicum
    Satoshi Mitsuhashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd Asahi machi, Machida Tokyo, Japan
    Biosci Biotechnol Biochem 70:2803-6. 2006
    ..These results suggest that the loss of MQO activity down-regulates the flux of the TCA cycle to maintain the redox balance and results in redirection of oxaloacetate into L-lysine biosynthesis...
  20. ncbi Signal transduction through the B cell antigen receptor is normal in ataxia-telangiectasia B lymphocytes
    Peter Speck
    Department of Microbiology-Immunology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Biol Chem 277:4123-7. 2002
    ..Further, signaling is blocked similarly in A-T and normal lymphoblastoid cells bearing wild-type EBV. In conclusion there is no evidence of any defect in B cell receptor signal transduction in A-T B cells...