Masato Ikeda

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. ncbi request reprint Elucidation of genes relevant to the microaerobic growth of Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Biosci Biotechnol Biochem 73:2806-8. 2009
  2. ncbi request reprint Amino acid production processes
    Masato Ikeda
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, 3 6 6, Asahi machi, Machida, Tokyo 194 8533, Japan
    Adv Biochem Eng Biotechnol 79:1-35. 2003
  3. ncbi request reprint Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 69:615-26. 2006
  4. pmc Development of biotin-prototrophic and -hyperauxotrophic Corynebacterium glutamicum strains
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Environ Microbiol 79:4586-94. 2013
  5. doi request reprint Sugar transport systems in Corynebacterium glutamicum: features and applications to strain development
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 96:1191-200. 2012
  6. doi request reprint Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Microbiol Biotechnol 90:1443-51. 2011
  7. ncbi request reprint A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, 399 4598, Nagano, Japan
    J Ind Microbiol Biotechnol 33:610-5. 2006
  8. doi request reprint Significance of the Cgl1427 gene encoding cytidylate kinase in microaerobic growth of Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 97:1259-67. 2013
  9. pmc Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Appl Environ Microbiol 76:7154-60. 2010
  10. doi request reprint The Cgl1281-encoding putative transporter of the cation diffusion facilitator family is responsible for alkali-tolerance in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Arch Microbiol 190:531-8. 2008

Collaborators

  • Hiroshi Mizoguchi
  • Mikiro Hayashi
  • Seiki Takeno
  • Junko Ohnishi
  • Satoshi Mitsuhashi
  • Shinji Matsumoto
  • Sung Jean Park
  • Richard Longnecker
  • Peter Speck
  • Nobuyoshi Tsukamoto
  • Daisuke Shirakura
  • Ryosuke Murata
  • Ryosuke Kobayashi
  • Mio Nakamura
  • Shinzaburo Ito
  • Hiroyuki Aoki
  • Shiori Ueno
  • Rie Fukai
  • Koji Ishizuka
  • Itaru Hamachi
  • Yuko Iko
  • Satoshi Yamaguchi
  • Kazuhito V Tabata
  • Hiroyuki Noji
  • Harunobu Komatsu
  • Kikuo Sen
  • Tatsuya Masaki
  • Tomoha Komatsu
  • Shingo Kakita
  • Min Duk Seo
  • Bong Jin Lee
  • Ritsuko Katahira
  • Suk Kyeong Lee
  • Howard M Lederman
  • Akiko Ikeda

Detail Information

Publications21

  1. ncbi request reprint Elucidation of genes relevant to the microaerobic growth of Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Biosci Biotechnol Biochem 73:2806-8. 2009
    ..Some of these genes showed cross-complementation of the mutants in oxygen-limiting static culture, suggesting the utility of these genes for improved growth and production under oxygen limitation...
  2. ncbi request reprint Amino acid production processes
    Masato Ikeda
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, 3 6 6, Asahi machi, Machida, Tokyo 194 8533, Japan
    Adv Biochem Eng Biotechnol 79:1-35. 2003
    ..Furthermore, the rapid strides in genome analysis are bound to revolutionize the strain improvement methodology...
  3. ncbi request reprint Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 69:615-26. 2006
    ....
  4. pmc Development of biotin-prototrophic and -hyperauxotrophic Corynebacterium glutamicum strains
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Environ Microbiol 79:4586-94. 2013
    ..1 μg to 1 g per liter. This bioassay proved that the engineered biotin prototroph of C. glutamicum produced biotin directly from glucose, albeit at a marginally detectable level (approximately 0.3 μg per liter). ..
  5. doi request reprint Sugar transport systems in Corynebacterium glutamicum: features and applications to strain development
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 96:1191-200. 2012
    ..glutamicum strains that express non-PTS routes instead of the original PTS. The potential practical advantages of the development of such strains are discussed...
  6. doi request reprint Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, Japan
    Appl Microbiol Biotechnol 90:1443-51. 2011
    ..When this strategy was applied to a defined lysine producer, the engineered strain displayed increased lysine production from glucose...
  7. ncbi request reprint A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production
    Masato Ikeda
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Minami minowa, 399 4598, Nagano, Japan
    J Ind Microbiol Biotechnol 33:610-5. 2006
    ..Here we describe the essence of our approach for strain reconstruction, and also discuss mechanisms of L-lysine hyperproduction unraveled by combining genomics with classical strain improvement...
  8. doi request reprint Significance of the Cgl1427 gene encoding cytidylate kinase in microaerobic growth of Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 97:1259-67. 2013
    ..These results indicate that CMP kinase plays an important role in normal nucleotide biosynthesis under an oxygen-limiting environment...
  9. pmc Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Appl Environ Microbiol 76:7154-60. 2010
    ..These results demonstrate effective l-lysine production by C. glutamicum with an additional source of NADPH during glycolysis...
  10. doi request reprint The Cgl1281-encoding putative transporter of the cation diffusion facilitator family is responsible for alkali-tolerance in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano 399 4598, Japan
    Arch Microbiol 190:531-8. 2008
    ..These results demonstrated that the putative transporter of the CDF family mediates resistance to cobalt and also plays a physiological role in alkaline pH tolerance in C. glutamicum...
  11. ncbi request reprint Anaerobic growth and potential for amino acid production by nitrate respiration in Corynebacterium glutamicum
    Seiki Takeno
    Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Nagano, 399 4598, Japan
    Appl Microbiol Biotechnol 75:1173-82. 2007
    ..Agar piece assays using L-lysine- and L-arginine-producing strains showed that production of both amino acids occurred anaerobically by nitrate respiration, indicating the potential of C. glutamicum for anaerobic amino acid production...
  12. pmc Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer
    Masato Ikeda
    BioProcess Development Center, Kyowa Hakko Bio Co, Ltd, Tsukuba, Ibaraki 305 0841, Japan m
    Appl Environ Microbiol 75:1635-41. 2009
    ..coli argB. This reconstructed strain displayed an enhanced performance, thus allowing significantly higher productivity of arginine/citrulline even at the suboptimal 38 degrees C...
  13. ncbi request reprint Characterization of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain
    Junko Ohnishi
    Bio Frontier Laboratories, Kyowa Hakko Kogyo Co Ltd, Machida, Tokyo, Japan
    Mutat Res 649:239-44. 2008
    ....
  14. ncbi request reprint A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum
    Mikiro Hayashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Machida, Tokyo 194 8533, Japan
    Appl Microbiol Biotechnol 72:783-9. 2006
    ..Transcriptome analysis revealed that many amino acid biosynthetic genes, including lysC-asd operon, were significantly upregulated in the leuC mutant in a rel-independent manner...
  15. ncbi request reprint A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum
    Junko Ohnishi
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Co, Ltd, Asahi machi, Machida, Tokyo 194 8533, Japan
    FEMS Microbiol Lett 242:265-74. 2005
    ....
  16. ncbi request reprint Disruption of malate:quinone oxidoreductase increases L-lysine production by Corynebacterium glutamicum
    Satoshi Mitsuhashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd Asahi machi, Machida Tokyo, Japan
    Biosci Biotechnol Biochem 70:2803-6. 2006
    ..These results suggest that the loss of MQO activity down-regulates the flux of the TCA cycle to maintain the redox balance and results in redirection of oxaloacetate into L-lysine biosynthesis...
  17. ncbi request reprint Expression and characterization of N-terminal domain of Epstein-Barr virus latent membrane protein 2A in Escherichia coli
    Sung Jean Park
    National Research Laboratory MPS, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, San 56 1, Shillim Dong, Kwanak gu, Seoul 151 742, Republic of Korea
    Protein Expr Purif 41:9-17. 2005
    ....
  18. ncbi request reprint Transcriptome analysis reveals global expression changes in an industrial L-lysine producer of Corynebacterium glutamicum
    Mikiro Hayashi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Tokyo, Japan
    Biosci Biotechnol Biochem 70:546-50. 2006
    ..These results suggest that a certain global regulatory mechanism is involved in the industrial levels of L-lysine production...
  19. ncbi request reprint Comparisons of potentials for L-lysine production among different Corynebacterium glutamicum strains
    Junko Ohnishi
    BioFrontier Laboratories, Kyowa Hakko Kogyo Co, Ltd, Tokyo, Japan
    Biosci Biotechnol Biochem 70:1017-20. 2006
    ..These results indicate the diversity among C. glutamicum strains in fermentative characters, as well as the importance of selecting a strain with industrially best performance...
  20. doi request reprint Photo gel-sol/sol-gel transition and its patterning of a supramolecular hydrogel as stimuli-responsive biomaterials
    Shinji Matsumoto
    Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Nishikyo ku, Kyoto, 615 8510, Japan
    Chemistry 14:3977-86. 2008
    ..These results demonstrated that the photoresponsive supramolecular hydrogel and the resulting nanomeshes may provide unique biomaterials for the spatiotemporal manipulation of various biomolecules and live bacteria...
  21. ncbi request reprint Signal transduction through the B cell antigen receptor is normal in ataxia-telangiectasia B lymphocytes
    Peter Speck
    Department of Microbiology Immunology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Biol Chem 277:4123-7. 2002
    ..Further, signaling is blocked similarly in A-T and normal lymphoblastoid cells bearing wild-type EBV. In conclusion there is no evidence of any defect in B cell receptor signal transduction in A-T B cells...