Hinako Ichikawa

Summary

Affiliation: Shinshu University
Country: Japan

Publications

  1. ncbi request reprint Cryopreservation of mouse embryoid bodies
    Hinako Ichikawa
    Department of Anatomy and Organ Technology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Cryobiology 54:290-3. 2007
  2. doi request reprint Unique kinetics of Oct3/4 microlocalization following dissociation of human embryonic stem cell colonies
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Ann Anat 195:50-6. 2013
  3. doi request reprint Bone morphogenetic protein-4 promotes induction of cardiomyocytes from human embryonic stem cells in serum-based embryoid body development
    Shunsuke Takei
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Am J Physiol Heart Circ Physiol 296:H1793-803. 2009
  4. doi request reprint In vitro transdifferentiation of HepG2 cells to pancreatic-like cells by CCl₄, D-galactosamine, and ZnCl₂
    Yoshiya Kanoh
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Japan
    Pancreas 40:1245-52. 2011
  5. doi request reprint Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Cryobiology 64:12-22. 2012
  6. ncbi request reprint Freeze-thawing single human embryonic stem cells induce e-cadherin and actin filament network disruption via g13 signaling
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Nagano, Japan
    Cryo Letters 32:516-24. 2011
  7. ncbi request reprint Localization of Liv2 as an immature hepatocyte marker in EB outgrowth
    Ikkei Takashimizu
    Department of Anatomy and Organ Technology, School of Medicine, ShinshuUniversity, 3 1 1 Asahi Matsumoto, Japan
    ScientificWorldJournal 9:190-9. 2009
  8. doi request reprint Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells
    Shin Ichi Mae
    Department of Histology and Embryology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Biochem Biophys Res Commun 393:877-82. 2010
  9. doi request reprint Hepatocyte differentiation from human ES cells using the simple embryoid body formation method and the staged-additional cocktail
    Katsunori Sasaki
    Department of Histology and Embryology, Shinshu University School of Medicine, Nagano 390 8621, Japan
    ScientificWorldJournal 9:884-90. 2009
  10. ncbi request reprint Investigation of the influence of cell density of human fibroblasts cryopreserved inside collagen sponges at various cooling rates
    Yumi Matsumura
    Graduate School of Medical Sciences Kitasato University, 1 15 1 Kitazato Sagamihara shi, Kanagawa, Japan
    Cryo Letters 28:337-46. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Cryopreservation of mouse embryoid bodies
    Hinako Ichikawa
    Department of Anatomy and Organ Technology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Cryobiology 54:290-3. 2007
    ..In conclusion, EBs frozen in the Program Freezer had higher survival adhesion rates compared to the BICELL and formed differentiated cells characteristic of the three embryonic germ layers...
  2. doi request reprint Unique kinetics of Oct3/4 microlocalization following dissociation of human embryonic stem cell colonies
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Ann Anat 195:50-6. 2013
    ..RhoA activation followed by dissociation disorders this system and accelerates cell death, which is partially suppressed by ROCK inhibition...
  3. doi request reprint Bone morphogenetic protein-4 promotes induction of cardiomyocytes from human embryonic stem cells in serum-based embryoid body development
    Shunsuke Takei
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Am J Physiol Heart Circ Physiol 296:H1793-803. 2009
    ..These findings showed that BMP-4 in combination with FBS at the appropriate time and concentrations significantly promotes cardiomyocyte induction from human ES cells...
  4. doi request reprint In vitro transdifferentiation of HepG2 cells to pancreatic-like cells by CCl₄, D-galactosamine, and ZnCl₂
    Yoshiya Kanoh
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Japan
    Pancreas 40:1245-52. 2011
    ..The objective of the study was to induce transdifferentiation of human hepatoma HepG2 cells into pancreatic-like cells without direct genetic intervention...
  5. doi request reprint Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Cryobiology 64:12-22. 2012
    ..Y-27632 can suppress cytokine interactions and the MAPK pathway, thereby reducing the occurrence of apoptosis, and is an effective cryoprotectant for hES cells...
  6. ncbi request reprint Freeze-thawing single human embryonic stem cells induce e-cadherin and actin filament network disruption via g13 signaling
    Hinako Ichikawa
    Department of Histology and Embryology, Shinshu University School of Medicine, Nagano, Japan
    Cryo Letters 32:516-24. 2011
    ..Considering these findings and that cell death was partly interrupted by Y-27632, E-cadherin and actin cytoskeleton network disruption through the G13 signaling pathway may cause hES cell death after freeze-thawing...
  7. ncbi request reprint Localization of Liv2 as an immature hepatocyte marker in EB outgrowth
    Ikkei Takashimizu
    Department of Anatomy and Organ Technology, School of Medicine, ShinshuUniversity, 3 1 1 Asahi Matsumoto, Japan
    ScientificWorldJournal 9:190-9. 2009
    ..This application would allow for the sole selection of immature hepatocytes and provide a useful tool for regenerative medicine...
  8. doi request reprint Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells
    Shin Ichi Mae
    Department of Histology and Embryology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Biochem Biophys Res Commun 393:877-82. 2010
    ....
  9. doi request reprint Hepatocyte differentiation from human ES cells using the simple embryoid body formation method and the staged-additional cocktail
    Katsunori Sasaki
    Department of Histology and Embryology, Shinshu University School of Medicine, Nagano 390 8621, Japan
    ScientificWorldJournal 9:884-90. 2009
    ..These results indicate that these combined methods promote EB formation and hepatocyte differentiation from hES cells...
  10. ncbi request reprint Investigation of the influence of cell density of human fibroblasts cryopreserved inside collagen sponges at various cooling rates
    Yumi Matsumura
    Graduate School of Medical Sciences Kitasato University, 1 15 1 Kitazato Sagamihara shi, Kanagawa, Japan
    Cryo Letters 28:337-46. 2007
    ..Results show that with increasing cell density, the post-thaw membrane integrity decreased. Therefore, in the cryopreservation of biological tissue, it seems high cell density is one factor which causes a decline in viability...