Research Topics


Shozo Yano


Affiliation: Shimane University
Country: Japan


  1. Tanabe S, Yano S, Mishima S, Nagai A. Physical inactivity and vitamin D deficiency in hospitalized elderlies. J Bone Miner Metab. 2019;: pubmed publisher
    ..97) scores, suggesting that vitamin D deficiency may affect physical activities. Most hospitalized elderly patients in Japan were deficient for vitamin D. In addition, physical inactivity is strongly associated with vitamin D deficiency. ..
  2. Notsu Y, Yano S, Shibata H, Nagai A, Nabika T. Plasma arginine/ADMA ratio as a sensitive risk marker for atherosclerosis: Shimane CoHRE study. Atherosclerosis. 2015;239:61-6 pubmed publisher
    ..05-0.88) in multiple logistic regression analysis for IMT 1.5 mm or more. Imbalance of Arg and ADMA is independently involved in the progression of atherosclerosis, and the Arg/ADMA ratio may be a sensitive marker for atherosclerosis. ..
  3. Takeda M, Hamano T, Kohno K, Yano S, Shiwaku K, Nabika T. Association Between Geographic Elevation, Bone Status, and Exercise Habits: The Shimane CoHRE Study. Int J Environ Res Public Health. 2015;12:7392-9 pubmed publisher
    ..Our results highlight the importance of considering residential environment and exercise habits when establishing promotion strategies to maintain bone status of the elderly people who live in rural mountainous areas. ..
  4. Yano S, Nabika T, Nagai A, Hamano T, Yamasaki M, Isomura M, et al. Interrelationship between glucose metabolism and undercarboxylated osteocalcin: a cross-sectional study in a community-dwelling population. Asia Pac J Clin Nutr. 2015;24:489-95 pubmed publisher
  5. Koike S, Yano S, Tanaka S, Sheikh A, Nagai A, Sugimoto T. Advanced Glycation End-Products Induce Apoptosis of Vascular Smooth Muscle Cells: A Mechanism for Vascular Calcification. Int J Mol Sci. 2016;17: pubmed publisher
    ..These findings might be important to understand the pathogenesis of vascular calcification in diabetes and CKD. ..
  6. Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T. Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells. BMC Cell Biol. 2007;8:51 pubmed
    ..Taken together, this study suggests that adiponectin stimulates the proliferation, differentiation, and mineralization of osteoblasts via the AdipoR1 and AMP kinase signaling pathways in autocrine and/or paracrine fashions. ..