Tsuyoshi Miyaoka

Summary

Affiliation: Shimane University
Country: Japan

Publications

  1. doi request reprint Yi-gan san for treatment of charles bonnet syndrome (visual hallucination due to vision loss): an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Clin Neuropharmacol 34:24-7. 2011
  2. doi request reprint Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 37:222-6. 2012
  3. ncbi request reprint Yokukansan promotes hippocampal neurogenesis associated with the suppression of activated microglia in Gunn rat
    Motohide Furuya
    Department of Psychiatry, Shimane University Faculty of Medicine, 89 1 Enya cho, Izumo 693 8501, Japan
    J Neuroinflammation 10:145. 2013
  4. doi request reprint Yokukansan (TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Phytomedicine 20:654-8. 2013
  5. ncbi request reprint Clinical potential of minocycline for schizophrenia
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    CNS Neurol Disord Drug Targets 7:376-81. 2008
  6. ncbi request reprint Fluid-attenuated inversion-recovery MR imaging in schizophrenia-associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Eur Psychiatry 20:327-31. 2005
  7. ncbi request reprint Urinary excretion of biopyrrins, oxidative metabolites of bilirubin, increases in patients with psychiatric disorders
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Eur Neuropsychopharmacol 15:249-52. 2005
  8. ncbi request reprint Yi-gan san for the treatment of borderline personality disorder: an open-label study
    Tsuyshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:150-4. 2008
  9. doi request reprint Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo, 693 8501, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:761-4. 2008
  10. doi request reprint Yi-gan san as adjunctive therapy for treatment-resistant schizophrenia: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Clin Neuropharmacol 32:6-9. 2009

Collaborators

Detail Information

Publications46

  1. doi request reprint Yi-gan san for treatment of charles bonnet syndrome (visual hallucination due to vision loss): an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Clin Neuropharmacol 34:24-7. 2011
    ..We aimed at evaluating both the efficacy and safety of YGS in patients with CBS...
  2. doi request reprint Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 37:222-6. 2012
    ....
  3. ncbi request reprint Yokukansan promotes hippocampal neurogenesis associated with the suppression of activated microglia in Gunn rat
    Motohide Furuya
    Department of Psychiatry, Shimane University Faculty of Medicine, 89 1 Enya cho, Izumo 693 8501, Japan
    J Neuroinflammation 10:145. 2013
    ..Although certain ingredients of YKS have potent anti-inflammatory activity, no study has determined if YKS has anti-inflammatory properties...
  4. doi request reprint Yokukansan (TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Phytomedicine 20:654-8. 2013
    ....
  5. ncbi request reprint Clinical potential of minocycline for schizophrenia
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    CNS Neurol Disord Drug Targets 7:376-81. 2008
    ..In addition, we extend our discussion to the potential applications of minocycline for combining this treatment with cellular and molecular therapy...
  6. ncbi request reprint Fluid-attenuated inversion-recovery MR imaging in schizophrenia-associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Eur Psychiatry 20:327-31. 2005
    ....
  7. ncbi request reprint Urinary excretion of biopyrrins, oxidative metabolites of bilirubin, increases in patients with psychiatric disorders
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Eur Neuropsychopharmacol 15:249-52. 2005
    ..These finding suggest that psychotic states are associated with an increase in the oxidative metabolites of bilirubin in human urine...
  8. ncbi request reprint Yi-gan san for the treatment of borderline personality disorder: an open-label study
    Tsuyshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:150-4. 2008
    ..We aimed at evaluating both efficacy and safety of yi-gan san in patients with well-defined BPD...
  9. doi request reprint Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo, 693 8501, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:761-4. 2008
    ..The authors examined the efficacy, tolerability, and safety of YGS in patients with tardive dyskinesia...
  10. doi request reprint Yi-gan san as adjunctive therapy for treatment-resistant schizophrenia: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Clin Neuropharmacol 32:6-9. 2009
    ..We aimed at evaluating both the efficacy and safety of YGS in patients with treatment-resistant schizophrenia...
  11. doi request reprint Minocycline as adjunctive therapy for schizophrenia: an open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Clin Neuropharmacol 31:287-92. 2008
    ....
  12. ncbi request reprint Possible antipsychotic effects of minocycline in patients with schizophrenia
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:304-7. 2007
    ..Moreover, it has been reported that minocycline might have antidepressant effects. We report two cases of acute schizophrenia with predominant catatonic symptoms that responded to minocycline...
  13. doi request reprint The effects of antipsychotics on behavioral abnormalities of the Gunn rat (unconjugated hyperbilirubinemia rat), a rat model of schizophrenia
    Keiko Tsuchie
    Department of Psychiatry, Faculty of Medicine, Shimane University, Japan
    Asian J Psychiatr 6:119-23. 2013
    ..In the present study, we assessed the effects of antipsychotics on Gunn rat behavioral abnormalities...
  14. pmc Yokukansan (TJ-54) for treatment of pervasive developmental disorder not otherwise specified and Asperger's disorder: a 12-week prospective, open-label study
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    BMC Psychiatry 12:215. 2012
    ..We aimed at evaluating both the efficacy and safety of TJ-54 in patients with well-defined PDD-NOS and Asperger's disorder...
  15. ncbi request reprint A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease
    Hideto Shinno
    Department of Psychiatry, Shimane University Faculty of Medicine, Izumo, Japan
    J Neurol Sci 260:132-8. 2007
    ..On the other hand, the neurochemical pathologies of the behavioral and psychological symptoms of dementia (BPSD) have not been sufficiently discussed. The aim of this study was to clarify the pathologies of BPSD in AD patients...
  16. doi request reprint Abnormalities in MRI signal intensity in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia
    Rei Wake
    Department of Psychological Medicine, Shimane University School of Medicine, 89 1 Enyacho, Izumo, Japan
    Aust N Z J Psychiatry 43:1057-69. 2009
    ..The purpose of the present study was to examine whether patients with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome; GS) have specific changes in signal intensity on magnetic resonance imaging (MRI)...
  17. ncbi request reprint Proton magnetic resonance spectroscopy (1H-MRS) of hippocampus, basal ganglia, and vermis of cerebellum in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University Medical School, 89 1 Enyacho, Izumo 693 8501, Japan
    J Psychiatr Res 39:29-34. 2005
    ..Whether patients with schizophrenia-associated idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome, GS) have specific changes in brain metabolism was examined in this study...
  18. ncbi request reprint Successful electroconvulsive therapy in major depression with fluvoxamine-induced bruxism
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane Medical University, Izumo, Japan
    J ECT 19:170-2. 2003
    ..Both the depressive symptoms and bruxism completely remitted after six treatments. Possible mechanisms of this effect are discussed...
  19. doi request reprint Evaluation of autonomic nervous system by salivary alpha-amylase level and heart rate variability in patients with schizophrenia
    Masa Ieda
    Department of Psychiatry, Faculty of Medicine, Shimane University, 89 1 Enya cho, Izumo, Shimane, 693 8501, Japan
    Eur Arch Psychiatry Clin Neurosci 264:83-7. 2014
    ..However, there were no significant differences between two groups in sympathetic nervous system (SNS) activity. We concluded that PNS might be suppressed and the SNS shows relatively high activity in schizophrenia. ..
  20. ncbi request reprint Yokukansan (TJ-54) for irritability associated with pervasive developmental disorder in children and adolescents: a 12-week prospective, open-label study
    Rei Wake
    Department of Psychiatry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan
    J Child Adolesc Psychopharmacol 23:329-36. 2013
    ..Recent studies indicate that TJ-54 may be safe and useful in treating behavioral and psychological symptoms in dementia patients. We aimed at evaluating both the efficacy and the safety of TJ-54 in patients with PDDs...
  21. pmc Morphological features of microglial cells in the hippocampal dentate gyrus of Gunn rat: a possible schizophrenia animal model
    Kristian Liaury
    Department of Psychiatry, Shimane University Faculty of Medicine, 89 1 Enya cho, Izumo 693 8501, Japan
    J Neuroinflammation 9:56. 2012
    ..In the present study, we examined how microglial cells respond to bilirubin toxicity in adult Gunn rats...
  22. ncbi request reprint Sleep disturbances and depression in the elderly in Japan
    Tsuruhei Sukegawa
    Department of Psychiatry, Shimane Medical University, Izumo City, Japan
    Psychiatry Clin Neurosci 57:265-70. 2003
    ..It is concluded that sleep disturbance and depression among the Japanese elderly are closely related symptoms. The features of sleep disturbance with depression differed with sex and age...
  23. ncbi request reprint Increased urinary excretion of biopyrrins, oxidative metabolites of bilirubin, in patients with schizophrenia
    Rei Yasukawa
    Department of Psychiatry, Shimane University School of Medicine, 89 1 Enyacho, Izumo 693 8501, Japan
    Psychiatry Res 153:203-7. 2007
    ..These findings indicate that the urinary biopyrrin level is a possible indicator that can be useful in the continuous monitoring of psychotic states in clinical practice...
  24. pmc Proton magnetic resonance spectroscopy of the anterior cingulate gyrus, insular cortex and thalamus in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)
    Rei Yasukawa
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    J Psychiatry Neurosci 30:416-22. 2005
    ..To examine whether patients with schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome [GS]) have specific changes in brain metabolism...
  25. doi request reprint Minocycline improves recognition memory and attenuates microglial activation in Gunn rat: a possible hyperbilirubinemia-induced animal model of schizophrenia
    Kristian Liaury
    Department of Psychiatry, Shimane University Faculty of Medicine, 89 1 Enya cho, Izumo 693 8501, Japan Department of Psychiatry, Hasanuddin University Faculty of Medicine, Jl Perintis Kemerdekaan Km 10, Makassar 90245, South Sulawesi, Indonesia Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 50:184-90. 2014
    ..On the other hand, there have been numerous reports that minocycline is effective in treating schizophrenia...
  26. ncbi request reprint Prevalence of restless legs syndrome in non-institutionalized Japanese elderly
    Soichi Mizuno
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Shimane, Japan
    Psychiatry Clin Neurosci 59:461-5. 2005
    ..46% male vs. 1.18% female, respectively). The prevalence of RLS may be lower in the Japanese elderly than that in Caucasian subjects. These results could enhance understanding of the differences in predisposition between the races...
  27. doi request reprint Hyperbilirubinemia-related behavioral and neuropathological changes in rats: a possible schizophrenia animal model
    Maiko Hayashida
    Department of Psychiatry, Shimane University Faculty of Medicine, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 33:581-8. 2009
    ..We examined the hyperbilirubinemia on behavioral and neuropathological changes in rats as a possible animal model of schizophrenia...
  28. pmc Prediction of response within the first 3 days to treatment with paroxetine for depression
    Takuji Inagaki
    Department of Psychiatry, Faculty of Medicine, Shimane University, Izumo, Japan
    Prim Care Companion J Clin Psychiatry 10:129-32. 2008
    ..01).Conclusion: In patients responding to paroxetine in the early stages of treatment, the prediction of response within the first 3 days using the self-rated HAM-D is suggested...
  29. ncbi request reprint Factors disturbing treatment for cancer in patients with schizophrenia
    Takuji Inagaki
    Department of Psychiatry, Faculty of Medicine, Shimane University, Izumo, Japan
    Psychiatry Clin Neurosci 60:327-31. 2006
    ..The important role of consultation-liaison psychiatrist in treating cancer patients is suggested. Some steps are proposed for managing schizophrenia patients with cancer who are not able to give informed consent...
  30. ncbi request reprint Echocardiographic investigation of pericardial effusion in a case of anorexia nervosa
    Takuji Inagaki
    Department of Psychiatry, Shimane Medical University, 89 1 Enya, Izumo, Shimane 693 8501, Japan
    Int J Eat Disord 33:364-6. 2003
    ..The measurement of serum BNP level may be a clinical parameter in such a case of pericardial effusion...
  31. ncbi request reprint Successful treatment of nocturnal eating/drinking syndrome with selective serotonin reuptake inhibitors
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane Medical University, Izumo, Japan
    Int Clin Psychopharmacol 18:175-7. 2003
    ..Treatment with a selective seroronin reuptake inhibitor (SSRI) was effective in controlling their episodes of nocturnal eating. To our knowledge, this is the first published case report of successful treatment with SSRIs in NE/DS...
  32. ncbi request reprint Korsakoff syndrome following chronic subdural hematoma
    Takuji Inagaki
    Department of Psychiatry, Shimane Medical University, Izumo, Japan
    Gen Hosp Psychiatry 25:364-6. 2003
    ....
  33. ncbi request reprint [Schizophrenia and idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)]
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine
    Seishin Shinkeigaku Zasshi 109:305-12. 2007
    ..From the viewpoint of the heterogeneity of schizophrenia, there may be a poor outcome for the subtype of schizophrenia with GS...
  34. ncbi request reprint Glia: an important target for anti-inflammatory and antidepressant activity
    Sadayuki Hashioka
    Department of Psychiatry, Faculty of Medicine, Shimane University, 89 1 Enya cho, Izumo, Shimane, 693 8501, Japan
    Curr Drug Targets 14:1322-8. 2013
    ..Moreover, antidepressants have the possibility to be useful treatment, not only for depression, but for a broad spectrum of neuroinflammatory and neurodegenerative disorders where the pathogenesis is associated with glial activation. ..
  35. doi request reprint Marked improvement in delirium with ramelteon: five case reports
    Motohide Furuya
    Department of Psychiatry, Faculty of Medicine, Shimane University School, Izumo, Japan
    Psychogeriatrics 12:259-62. 2012
    ..This suggests that correction of the circadian rhythm disturbance, one of the main symptoms of delirium, plays a crucial role in its treatment and sheds new light on a therapeutic strategy for treatment of delirium...
  36. pmc May salivary alpha-amylase level be a useful tool for assessment of the severity of schizophrenia and evaluation of therapy? A case report
    Masa Ieda
    Department of Psychiatry, Shimane University of Medicine, 89 1 Enyacho, Izumo 6938501, Japan
    Case Rep Psychiatry 2012:747104. 2012
    ..Conclusion. We consider that measurement of the sAA level may be one of the useful biological markers for assessment of psychotic state and efficacy of treatment in patients with schizophrenia...
  37. ncbi request reprint New approaches to antidepressant drug design: cytokine-regulated pathways
    Akira Nishida
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Curr Pharm Des 15:1683-7. 2009
    ..Therefore, this review focuses on the association between depressive disorder and cytokines and discusses the strategies for developing new cytokine-based antidepressant drugs...
  38. doi request reprint Pathogenesis and symptomatology of hallucinations (delusions) of organic brain disorder and schizophrenia
    Jun Horiguchi
    Department of Psychiatry, Shimane University School of Medicine, Izumo, Japan
    Psychogeriatrics 9:73-6. 2009
    ....
  39. ncbi request reprint CSF iron, ferritin and transferrin levels in restless legs syndrome
    Soichi Mizuno
    Department of Psychiatry, Shimane University School of Medicine, Shimane, Japan
    J Sleep Res 14:43-7. 2005
    ..These results indicate low brain iron concentration caused by the dysfunction of iron transportation from serum to CNS in patients with idiopathic RLS...
  40. ncbi request reprint Novel class of neural stochastic resonance and error-free information transfer
    Hideaki Yasuda
    Department of Psychiatry, School of Medicine, Shimane University, 89 1 Enyacho, Izumo City, Shimane 693 8501, Japan
    Phys Rev Lett 100:118103. 2008
    ..The neuron thus acts as an error-free detector for weak signals. An integrate-and-fire model with short-term synaptic depression convincingly validates our experimental findings for SR in the human tactile blink reflex...
  41. ncbi request reprint Late onset anorexia nervosa: two case reports
    Takuji Inagaki
    Department of Psychiatry, Shimane Medical University, Enya, Izumo, Japan
    Int J Psychiatry Med 32:91-5. 2002
    ..Some patients develop an eating disorder at a late age. It is worth investigating why this syndrome develops at such widely different ages...
  42. ncbi request reprint [Schizophrenia and idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)]
    Tsuyoshi Miyaoka
    Department of Psychiatry, Shimane University School of Medicine
    Seishin Shinkeigaku Zasshi 113:361-7. 2011
    ..From the viewpoint of the heterogeneity of schizophrenia, there may be a poor outcome for the subtype of schizophrenia with GS...
  43. ncbi request reprint Decreased levels of whole blood glial cell line-derived neurotrophic factor (GDNF) in remitted patients with mood disorders
    Minoru Takebayashi
    Institute of Clinical Research, Department of Psychiatry, National Hospital Organization NHO Kure Medical Center, Kure, and Department of Neuroscience, Yamaguchi University School of Medicine, Japan
    Int J Neuropsychopharmacol 9:607-12. 2006
    ..Our study suggests that lower GDNF levels might be involved in the pathophysiology of mood disorders, although this preliminary study has several limitations...
  44. doi request reprint Serum cytokine and chemokine profiles in neonates with meconium aspiration syndrome
    Kaoru Okazaki
    Division of Neonatology, Tokyo Metropolitan Hachioji Children s Hospital, 4 33 13 Daimachi, Hachioji, Tokyo 193 0931, Japan
    Pediatrics 121:e748-53. 2008
    ..To clarify any such association, we compared various serum cytokine and chemokine profiles in patients with and without meconium aspiration syndrome...
  45. doi request reprint Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor
    Shusaku Uchida
    Division of Neuropsychiatry, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1 1 1 Minamikogushi, Ube, Yamaguchi 755 8505, Japan
    Eur J Neurosci 27:2250-61. 2008
    ....
  46. doi request reprint Elevation of high-mobility group box 1 concentration in asphyxiated neonates
    Kaoru Okazaki
    Tokyo Metropolitan Hachioji Children s Hospital, Tokyo, Japan
    Neonatology 94:105-9. 2008
    ..However, the physiological significance of HMGB-1 in asphyxia is poorly understood...