Hitoshi Yasuda

Summary

Affiliation: Shiga University of Medical Science
Country: Japan

Publications

  1. ncbi request reprint Diabetic neuropathy and nerve regeneration
    Hitoshi Yasuda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Seta, Otsu, Japan
    Prog Neurobiol 69:229-85. 2003
  2. ncbi request reprint Effect of protein kinase Cbeta inhibitor on Ca2+ homeostasis in diabetic sensory neurons
    Masayuki Tahara
    Division of Neurology, Department of Internal Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Neuroreport 17:683-8. 2006
  3. ncbi request reprint Inhibitory action of protein kinase Cbeta inhibitor on tetrodotoxin-resistant Na+ current in small dorsal root ganglion neurons in diabetic rats
    Fumiko Hayase
    Division of Neurology, Department of Internal Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neurosci Lett 417:90-4. 2007
  4. pmc Isolation of specific peptides that home to dorsal root ganglion neurons in mice
    Jiro Oi
    Department of Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neurosci Lett 434:266-72. 2008
  5. pmc The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy
    Tomoya Terashima
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Proc Natl Acad Sci U S A 102:12525-30. 2005
  6. ncbi request reprint Rationale and usefulness of newly devised abbreviated diagnostic criteria and staging for diabetic polyneuropathy
    Hitoshi Yasuda
    Faculty of Nursing, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Diabetes Res Clin Pract 77:S178-83. 2007
  7. pmc Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus
    Hiroshi Urabe
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Nat Commun 4:1526. 2013
  8. pmc Brain-derived neurotrophic factor from bone marrow-derived cells promotes post-injury repair of peripheral nerve
    Yoshinori Takemura
    Department of Orthopaedic Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan
    PLoS ONE 7:e44592. 2012
  9. ncbi request reprint Protein kinase Cbeta selective inhibitor LY333531 attenuates diabetic hyperalgesia through ameliorating cGMP level of dorsal root ganglion neurons
    Hyoh Kim
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Diabetes 52:2102-9. 2003
  10. pmc Inactivation of TNF-α ameliorates diabetic neuropathy in mice
    Isamu Yamakawa
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Am J Physiol Endocrinol Metab 301:E844-52. 2011

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Diabetic neuropathy and nerve regeneration
    Hitoshi Yasuda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Seta, Otsu, Japan
    Prog Neurobiol 69:229-85. 2003
    ..For this purpose, especially clinically, skin biopsy, by which cutaneous nerve pathology including nerve regeneration can be morphometrically evaluated, might be a safe and useful examination...
  2. ncbi request reprint Effect of protein kinase Cbeta inhibitor on Ca2+ homeostasis in diabetic sensory neurons
    Masayuki Tahara
    Division of Neurology, Department of Internal Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Neuroreport 17:683-8. 2006
    ..These results suggest that LY333531 has an ameliorating effect on calcium homeostasis of diabetic sensory neurons via mitochondrial calcium buffering...
  3. ncbi request reprint Inhibitory action of protein kinase Cbeta inhibitor on tetrodotoxin-resistant Na+ current in small dorsal root ganglion neurons in diabetic rats
    Fumiko Hayase
    Division of Neurology, Department of Internal Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neurosci Lett 417:90-4. 2007
    ....
  4. pmc Isolation of specific peptides that home to dorsal root ganglion neurons in mice
    Jiro Oi
    Department of Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neurosci Lett 434:266-72. 2008
    ....
  5. pmc The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy
    Tomoya Terashima
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Proc Natl Acad Sci U S A 102:12525-30. 2005
    ..These results suggest that bone-marrow-derived cells may play an important role in the pathogenesis of diabetic complications...
  6. ncbi request reprint Rationale and usefulness of newly devised abbreviated diagnostic criteria and staging for diabetic polyneuropathy
    Hitoshi Yasuda
    Faculty of Nursing, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Diabetes Res Clin Pract 77:S178-83. 2007
    ..Staging was almost consistent between the new staging system and Dyck's staging (gold standard) and nerve function deteriorated with increasing stage, suggesting that usefulness and rationale of this staging system is well substantiated...
  7. pmc Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus
    Hiroshi Urabe
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Nat Commun 4:1526. 2013
    ..Our results suggest a novel mechanism of feeding control based on the production of BDNF by haematopoietic cells and highlight a potential new therapeutic route for the treatment of obesity...
  8. pmc Brain-derived neurotrophic factor from bone marrow-derived cells promotes post-injury repair of peripheral nerve
    Yoshinori Takemura
    Department of Orthopaedic Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan
    PLoS ONE 7:e44592. 2012
    ..These results suggested that the attenuated recovery of the BDNF+/- mice was rescued by the transplantation of BMCs and that BDNF from BMDCs has an essential role in nerve repair...
  9. ncbi request reprint Protein kinase Cbeta selective inhibitor LY333531 attenuates diabetic hyperalgesia through ameliorating cGMP level of dorsal root ganglion neurons
    Hyoh Kim
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Diabetes 52:2102-9. 2003
    ..The expressions of nNOS and TTX-R Na channels were not changed with LY treatment. These results suggest that LY is effective for treating diabetic hyperalgesia through ameliorating the decrease in the nNOS-cGMP system...
  10. pmc Inactivation of TNF-α ameliorates diabetic neuropathy in mice
    Isamu Yamakawa
    Department of Molecular Genetics in Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Am J Physiol Endocrinol Metab 301:E844-52. 2011
    ..Infliximab, an agent currently in clinical use, is effective in targeting TNF-α action and expression and amelioration of diabetic neuropathy in mice...
  11. ncbi request reprint Antiganglion neuron antibodies correlate with neuropathy in Sjögren's syndrome
    Yoshiko Murata
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan 520 2192
    Neuroreport 16:677-81. 2005
    ..These results suggest that antiganglion neuron antibodies may contribute to the pathogenesis of sensory neuropathy with Sjögren's syndrome...
  12. ncbi request reprint Cytosolic Ca2+ under high glucose with suppressed Na+/K+ pump activity in rat sensory neurons
    Mitsuru Sanada
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neuroreport 15:197-201. 2004
    ..These results suggest that a combination of high glucose and suppressed Na+/K+ pump activity potentiates the [Ca2+]i elevation stimulated by activation of the voltage-gated Ca2+ channels in rat DRG neurons...
  13. ncbi request reprint Hereditary motor and sensory neuropathy (proximal dominant form, HMSN-P) among Brazilians of Japanese ancestry
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga 520 2192, Japan
    Clin Neurol Neurosurg 109:830-2. 2007
    ..HMSN-P should no longer be regarded as an endemic condition limited to Okinawa...
  14. ncbi request reprint [Symptomatic treatment of painful diabetic neuropathy]
    Kengo Maeda
    Department of Medicine, Shiga University of Medical Science
    Nihon Rinsho 63:609-13. 2005
  15. ncbi request reprint Amelioration of retarded neurite outgrowth of dorsal root ganglion neurons by overexpression of PKCdelta in diabetic rats
    Yoshio Sakaue
    Department of Medicine, Shiga University of Medical Science, Seta, Otsu, Shiga 520 2192 Japan
    Neuroreport 14:431-6. 2003
    ..This observation provides a useful clue for the treatment of diabetic neuropathy...
  16. ncbi request reprint Constipation and segmental abdominal paresis followed by herpes zoster
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science
    Intern Med 46:1487-8. 2007
  17. pmc Properties of the Na+/K+ pump current in small neurons from adult rat dorsal root ganglia
    Kanako Hamada
    Department of Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Br J Pharmacol 138:1517-27. 2003
    ..6 mM, respectively). 5. Thus, the present investigation provides functional evidence to suggest that the Na(+)/K(+) ATPase comprises two functionally distinct isozymes as expected for alpha1beta1 and alpha3beta1 in rat small DRG neurons...
  18. ncbi request reprint Prevalence and major risk factors of reduced flow volume in lower extremities with normal ankle-brachial index in Japanese patients with type 2 diabetes
    Eiji Suzuki
    Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
    Diabetes Care 26:1764-9. 2003
    ..To clarify the prevalence and major risk factors of reduced flow volume in lower extremities with normal ankle-brachial index (ABI) in Japanese patients with type 2 diabetes...
  19. ncbi request reprint Internal capsule infarction showing leg monoparesis
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu
    Intern Med 46:1273. 2007
  20. ncbi request reprint Lateropulsion due to a lesion of the dorsal spinocerebellar tract
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Japan
    Intern Med 44:1295-7. 2005
    ..Lateropulsion caused by DSCT infarction could be a prodromal symptom of perfusion failure of a vertebral artery or the posterior inferior cerebellar artery...
  21. ncbi request reprint [Role of Ca2+ channels in the pathogenesis of diabetic neuropathy]
    Mitsuru Sanada
    Division of Neurology, Department of Internal Medicine, Shiga University of Medical Science
    Nihon Rinsho 63:647-51. 2005
  22. ncbi request reprint [A case of stroke-like episode of MELAS of which progressive spread would be prevented by edaravone]
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science
    Rinsho Shinkeigaku 45:416-21. 2005
    ..Edaravone could not rescue neurons in the initial lesion. Although more numbers of cases are needed to establish the effect of edaravone on MELAS, it could minimize the neurological deficits after stroke-like episode of MELAS...
  23. ncbi request reprint A case of myeloperoxidase-antineutrophil cytoplasmic antibody positive-polyarteritis nodosa complicated by interstitial pneumonia and rapidly progressive renal failure
    Toshiro Sugimoto
    Department of Medicine, Shiga University of Medical Science, Seta, Otsu, 520 2192, Japan
    Clin Rheumatol 26:429-32. 2007
    ..Tissue biopsy of the clinically affected organ should be considered in anyone suspected to have vasculitis...
  24. ncbi request reprint [Diabetic polyneuropathy and ACE gene polymorphism]
    Hitoshi Yasuda
    Department of Medicine, Shiga University of Medical Science
    Nihon Rinsho 63:652-6. 2005
  25. ncbi request reprint [Recent trends of diabetic neuropathy]
    Hitoshi Yasuda
    Department of Medicine, Shiga University of Medical Science, Setagetsurincho, Japan
    No To Shinkei 56:373-83. 2004
  26. ncbi request reprint SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death
    Tomoya Terashima
    Division of Neurology, Department of Medicine, Shiga University of Medical Science, Otsu, Shiga 520 2192, Japan
    Neuroreport 13:2359-64. 2002
    ..These results suggest that SUMO-1 is implicated in the pathogenesis of DRPLA and accelerates aggregate formation and cell death...
  27. ncbi request reprint [Severe Graves' ophthalmopathy accompanied by myasthenia gravis]
    Kengo Maeda
    Division of Neurology, Department of Medicine, Shiga University of Medical Science
    Rinsho Shinkeigaku 46:266-9. 2006
    ..For the good prognosis of the eye movement, orbital decompression might be recommended in the severe Graves' ophthalmopathy accompanied by the optic neuropathy and/or ophthalmoplegia with proptosis...
  28. ncbi request reprint [A case of retrobulbar optic neuritis associated with Sjögren syndrome which remitted spontaneously]
    Kengo Maeda
    Department of Neurology, Shiga University of Medical Science, Tsukinowa machi, Seta, Otsu shi, Shiga 520 2192, Japan
    No To Shinkei 54:997-1001. 2002
    ..Visual acuity and MRI findings were remitted spontaneously. This case is distinguished from multiple sclerosis and vasculitis or ischemic mechanism(s) associated with autoantibodies might play a role in the development of the disease...
  29. ncbi request reprint Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin
    Hideto Kojima
    Third Department of Medicine, Shiga University of Medical Science, Shiga, Japan
    Diabetes 51:1398-408. 2002
    ..In summary, our results indicated that immature intestinal stem cells can differentiate into insulin-producing cells given the ability to express the transcription factors Pdx-1 and Isl-1...
  30. ncbi request reprint Demyelinating and axonal features of Charcot-Marie-Tooth disease with mutations of myelin-related proteins (PMP22, MPZ and Cx32): a clinicopathological study of 205 Japanese patients
    Naoki Hattori
    Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Brain 126:134-51. 2003
    ....