Masako Okawa

Summary

Affiliation: Shiga University of Medical Science
Country: Japan

Publications

  1. ncbi request reprint Influence of age or circadian time on Bcl-2 and Bax mRNA expression in the rat hippocampus after corticosterone exposure
    Atsushi Yoshimura
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan
    Brain Res Bull 73:254-8. 2007
  2. ncbi request reprint Circadian rhythm sleep disorders: characteristics and entrainment pathology in delayed sleep phase and non-24-h sleep-wake syndrome
    Masako Okawa
    Department of Sleep Medicine, Shiga University of Medical Science, Otsu, Japan
    Sleep Med Rev 11:485-96. 2007
  3. pmc A before and after comparison of the effects of forest walking on the sleep of a community-based sample of people with sleep complaints
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Biopsychosoc Med 5:13. 2011
  4. ncbi request reprint [Sleep-wake rhythm disorders]
    Masako Okawa
    Department of Psychiatry, Shiga University of Medical Science, Tsukinowa cho, Otsu shi, Shiga 520 2192, Japan
    No To Shinkei 55:35-43. 2003
  5. ncbi request reprint The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients
    Mikito Ueda
    Department of Psychiatry, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520 2192, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:486-91. 2006
  6. ncbi request reprint Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia
    Kazutaka Shimoda
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 26:261-5. 2002
  7. ncbi request reprint Differences in emotional distress between breast tumor patients with emotional inhibition and those with emotional expression
    Yumi Iwamitsu
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Shiga, Japan
    Psychiatry Clin Neurosci 57:289-94. 2003
  8. ncbi request reprint The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients
    Kazutaka Shimoda
    Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan
    J Clin Psychopharmacol 22:371-8. 2002
  9. ncbi request reprint [DISC1 and schizophrenia]
    Yuji Ozeki
    Department of Psychiatry, Shiga University of Medical Science, Setatsukinowacho, Otsu, 520 2192 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 24:87-91. 2004
  10. ncbi request reprint Larger phase angle between sleep propensity and melatonin rhythms in sighted humans with non-24-hour sleep-wake syndrome
    Makoto Uchiyama
    Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ichikawa, Japan
    Sleep 25:83-8. 2002

Collaborators

  • T Someya
  • Hajime Abe
  • Yumi Iwamitsu
  • Yuji Ozeki
  • Akira Sawa
  • Tsuyoshi Watanabe
  • Takashi Ebisawa
  • H Tagaya
  • Takashi Ohnishi
  • Yukihiko Shirayama
  • Atsuko Takano
  • Masaaki Ikeda
  • Norio Ozaki
  • Katsuya Nagai
  • Yuriko Doi
  • Takashi Asada
  • Makoto Uchiyama
  • Kiyohisa Takahashi
  • Kazutaka Shimoda
  • Masahiko Hiroki
  • Naofumi Kajimura
  • Kayo Shibui
  • Masaaki Kato
  • Toru Nakajima
  • Emi Morita
  • Tatsuro Hayakawa
  • Sachiyo Morita
  • Genta Hirokane
  • Yuichi Kamei
  • Atsushi Yoshimura
  • Mikito Ueda
  • Kenichi Ogawa
  • Hidenao Fukuyama
  • Hiroshi Matsuda
  • Masami Nishikawa
  • Harumasa Takano
  • Takeshi Uema
  • Yutaka Takayama
  • Etsuko Imabayashi
  • Atsushi Kamiya
  • Masako Shirayama
  • Toshio Iwase
  • Aya Yokono
  • Keiko Kim
  • Tomio Kubota
  • Saburo Takahashi
  • Tomiyasu Miyaura
  • Soichiro Miyazaki
  • Makoto Imai
  • Seiichiro Jinde
  • Akira Masui
  • Nobumasa Kato
  • Hirohiko Kanai
  • Kazufumi Akiyama
  • Ken ichiro Kubo
  • Chikako Kudo
  • Jujiro Urata
  • Christopher A Ross
  • Richard Youn
  • Mary E Hatten
  • Manabu Takaki
  • Kazunori Nakajima
  • Toshifumi Tomoda
  • Una Park
  • Naoya Sawamura
  • Masanori Sekimoto
  • Hideharu Iida
  • Shuichiro Shirakawa
  • Mariko Sugishita
  • Toru Hori
  • Hiroyuki Suzuki
  • Kimio Yoshimura
  • Xin Tan
  • Toshio Yamauchi
  • Shojiro Inoue
  • Yuichi Inoue
  • Kazuo Mishima
  • Masahiko Nomura
  • Yoshinao Kudo
  • Masaaki Katoh
  • Naoto Yamada
  • Ryoichi Toyoshima

Detail Information

Publications24

  1. ncbi request reprint Influence of age or circadian time on Bcl-2 and Bax mRNA expression in the rat hippocampus after corticosterone exposure
    Atsushi Yoshimura
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan
    Brain Res Bull 73:254-8. 2007
    ..Our results emphasize the importance of circadian time as well as age as a factor influencing the stress paradigm...
  2. ncbi request reprint Circadian rhythm sleep disorders: characteristics and entrainment pathology in delayed sleep phase and non-24-h sleep-wake syndrome
    Masako Okawa
    Department of Sleep Medicine, Shiga University of Medical Science, Otsu, Japan
    Sleep Med Rev 11:485-96. 2007
    ..Treatment procedures and prevention of the syndromes require further attention using behavioral, environmental, and psychiatric approaches, since an increasing number of patients in modern society suffer from these disorders...
  3. pmc A before and after comparison of the effects of forest walking on the sleep of a community-based sample of people with sleep complaints
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Biopsychosoc Med 5:13. 2011
    ..abstract:..
  4. ncbi request reprint [Sleep-wake rhythm disorders]
    Masako Okawa
    Department of Psychiatry, Shiga University of Medical Science, Tsukinowa cho, Otsu shi, Shiga 520 2192, Japan
    No To Shinkei 55:35-43. 2003
  5. ncbi request reprint The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients
    Mikito Ueda
    Department of Psychiatry, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520 2192, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:486-91. 2006
    ..The present results suggest that having one non-functional allele is the marker for high plasma concentration of PAX when relatively high daily dose of PAX is administered...
  6. ncbi request reprint Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia
    Kazutaka Shimoda
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 26:261-5. 2002
    ..2 +/- 16.6 and 59.0 +/- 17.6 ng/ml/mg/kg, respectively, df = 28, P = .22). The present study suggests that the genotyping of CYP1A2 cannot predict the steady state plasma levels of HAL in male smoking schizophrenics...
  7. ncbi request reprint Differences in emotional distress between breast tumor patients with emotional inhibition and those with emotional expression
    Yumi Iwamitsu
    Department of Psychiatry, Shiga University of Medical Science, Otsu, Shiga, Japan
    Psychiatry Clin Neurosci 57:289-94. 2003
    ..These results suggest that it may be therapeutic to advise breast cancer patients to express their negative emotion...
  8. ncbi request reprint The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients
    Kazutaka Shimoda
    Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan
    J Clin Psychopharmacol 22:371-8. 2002
    ..Mother compound AT is shunted via hydroxylation pathways from AT to EHAT and ZHAT in the subjects with homozygotes of mutated alleles of CYP2C19 in order to compensate for the decreased capacity to desmethylate AT...
  9. ncbi request reprint [DISC1 and schizophrenia]
    Yuji Ozeki
    Department of Psychiatry, Shiga University of Medical Science, Setatsukinowacho, Otsu, 520 2192 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 24:87-91. 2004
    ..This concept fits with many historical observations found for schizophrenia in association with neurodevelopmental abnormalities. DISC1 may become one of the key molecules in studying the pathogenesis of schizophrenia...
  10. ncbi request reprint Larger phase angle between sleep propensity and melatonin rhythms in sighted humans with non-24-hour sleep-wake syndrome
    Makoto Uchiyama
    Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ichikawa, Japan
    Sleep 25:83-8. 2002
    ..This study was aimed to clarify phase angle between sleep propensity and the circadian pacemaker in patients with non-24-hour sleep-wake syndrome (Non-24)...
  11. ncbi request reprint Effects of nocturnal bright light on saliva melatonin, core body temperature and sleep propensity rhythms in human subjects
    Tomio Kubota
    Department of Occupational Therapy, Saitama Prefectural University, Sannomiya, 343 8540, Koshigaya, Japan
    Neurosci Res 42:115-22. 2002
    ....
  12. ncbi request reprint Clinical analyses of sighted patients with non-24-hour sleep-wake syndrome: a study of 57 consecutively diagnosed cases
    Tatsuro Hayakawa
    Department of Psychiatry, Kohnodai Hospital, National Center of Neurology and Psychiatry, Kohnodai, Ichikawa, Japan
    Sleep 28:945-52. 2005
    ..The objective of this study was to clarify the clinical features of sighted patients with non-24-hour sleep-wake syndrome...
  13. ncbi request reprint Non-rapid-eye-movement sleep propensity after sleep deprivation in human subjects
    Hirokuni Tagaya
    Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, 1 7 3 Kohnodai, Ichikawa, 272 0827, Chiba, Japan
    Neurosci Lett 323:17-20. 2002
    ..These results suggest that the occurrence of NREM sleep is modulated by a circadian pacemaker...
  14. ncbi request reprint Mutation screening of the human Clock gene in circadian rhythm sleep disorders
    Toshio Iwase
    Department of Neuropsychiatry, Saitama Medical School, 38 Morohongo, Moroyama cho, Iruma gun, 350 0495, Japan
    Psychiatry Res 109:121-8. 2002
    ..Polymorphisms in the coding region of the hClock gene are unlikely to play an important role in the development of DSPS or N-24. The possible contribution of the T3111C polymorphism to DSPS susceptibility should be studied further...
  15. ncbi request reprint A missense variation in human casein kinase I epsilon gene that induces functional alteration and shows an inverse association with circadian rhythm sleep disorders
    Atsuko Takano
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Osaka, Japan
    Neuropsychopharmacology 29:1901-9. 2004
    ..8-fold more active than wild-type CKIepsilon. These results indicate that the N408 allele in CKIepsilon plays a protective role in the development of DSPS and N-24 through alteration of the enzyme activity...
  16. ncbi request reprint Anxiety, emotional suppression, and psychological distress before and after breast cancer diagnosis
    Yumi Iwamitsu
    Department of Medical Psychology, Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan
    Psychosomatics 46:19-24. 2005
    ..Such patients need psychological interventions, including encouragement to express and communicate their emotions, immediately after disclosure of the diagnosis to help maintain psychological adjustment in the face of the disease...
  17. ncbi request reprint The psychological aspects of patients with delayed sleep phase syndrome (DSPS)
    Masako Shirayama
    Department of Psychiatry, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Japan
    Sleep Med 4:427-33. 2003
    ..The current study attempts to define the psychological features of patients with delayed sleep-phase syndrome (DSPS)...
  18. ncbi request reprint [Aims of sleep psychiatry]
    Masako Okawa
    Seishin Shinkeigaku Zasshi 108:1201. 2006
  19. ncbi request reprint High plasma concentrations of paroxetine impede clinical response in patients with panic disorder
    Takashi Watanabe
    Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Ther Drug Monit 29:40-4. 2007
    ..2 in the equation above, plasma concentration of paroxetine is calculated to be about 25 ng/mL, which is suggested to be the upper end of the therapeutic window for the initial phase of the treatment with paroxetine for panic disorder...
  20. ncbi request reprint Periodic leg movements during sleep in Japanese community-dwelling adults based on the assessments of their bed partners
    Yuriko Doi
    Department of Epidemiology, National Institute of Public Health, Wako, Saitama, Japan
    J Epidemiol 13:259-65. 2003
    ..The present study was a cross-sectional epidemiologic study to estimate the prevalence of PLMS and examine the associated factors of PLMS in Japanese community-dwelling adults...
  21. ncbi request reprint A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
    Atsushi Kamiya
    Department of Psychiatry Neurobiology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, CMSC 8 117, Baltimore, MD 21287, USA
    Nat Cell Biol 7:1167-78. 2005
    ..These results indicate that DISC1 is involved in cerebral cortex development, and suggest that loss of DISC1 function may underlie neurodevelopmental dysfunction in schizophrenia...
  22. ncbi request reprint Effect of benzodiazepine hypnotic triazolam on relationship of blood pressure and Paco2 to cerebral blood flow during human non-rapid eye movement sleep
    Masahiko Hiroki
    Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Neurophysiol 95:2293-303. 2006
    ....
  23. ncbi request reprint The relation between negative emotional suppression and emotional distress in breast cancer diagnosis and treatment
    Yumi Iwamitsu
    Department of Medical Psychology, Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan
    Health Commun 18:201-15. 2005
    ..Also, patients who suppress anger and anxiety felt strong psychological distress. We suggest that it is essential to encourage suppressive patients to express both negative and positive emotion clearly and appropriately...
  24. ncbi request reprint Cerebral white matter blood flow is constant during human non-rapid eye movement sleep: a positron emission tomographic study
    Masahiko Hiroki
    Human Brain Research Center, Kyoto University Graduate School of Medicine, Sakyo ku, Kyoto, Japan
    J Appl Physiol 98:1846-54. 2005
    ..637, R = 0.31) (P = 0.044). The cerebral white matter CBF keeps constant during NREM sleep as well as the occipital cortical CBF, and may be specifically regulated by both CO(2) vasoreactivity and pressure autoregulation...