Keiko Yamada

Summary

Affiliation: Sapporo Medical University
Country: Japan

Publications

  1. ncbi Degradation of vitamin B12 in dietary supplements
    Keiko Yamada
    Department of Liberal Arts and Sciences, School of Health Sciences, Sapporo Medical University, Sapporo, Japan
    Int J Vitam Nutr Res 78:195-203. 2008
  2. ncbi Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells
    Keiko Yamada
    Department of Liberal Arts and Sciences, School of Health Sciences, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
    Biochem Biophys Res Commun 305:101-7. 2003
  3. ncbi The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain
    Shin ichi Imai
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo, 060 8556, Japan
    Biochem J 382:957-66. 2004
  4. ncbi Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation
    Shuichi Tsushima
    Department of Biochemistry, Sapporo Medical University School of Medicine, South 1 West 17, Chuo Ku, Sapporo 060 8556, Japan
    J Biol Chem 279:28603-13. 2004
  5. ncbi Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation
    Kenji Yanagisawa
    Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan
    Biochim Biophys Acta 1771:462-74. 2007
  6. ncbi Analyses of non-leucine-rich repeat (non-LRR) regions intervening between LRRs in proteins
    Norio Matsushima
    Sapporo Medical University Center for Medical Education, Sapporo, Hokkaido 060 8556, Japan
    Biochim Biophys Acta 1790:1217-37. 2009
  7. ncbi Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions
    Fumio Sakane
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
    J Biol Chem 277:43519-26. 2002
  8. ncbi Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
    Norio Matsushima
    School of Health Sciences, Sapporo Medical University, Hokkaido, Japan
    BMC Genomics 8:124. 2007
  9. ncbi Diacylglycerol kinases: emerging downstream regulators in cell signaling systems
    Hideo Kanoh
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South West 17, Sapporo 060 8556, Japan
    J Biochem 131:629-33. 2002
  10. ncbi Copper binding to plant ozone-inducible proteins (OI2-2 and OI14-3)
    Masakatsu Kamiya
    Division of Biological Sciences, Graduate School of Science, Hokkaido University, 060 0810, Sapporo, Japan
    Biochem Biophys Res Commun 314:908-15. 2004

Collaborators

Detail Information

Publications10

  1. ncbi Degradation of vitamin B12 in dietary supplements
    Keiko Yamada
    Department of Liberal Arts and Sciences, School of Health Sciences, Sapporo Medical University, Sapporo, Japan
    Int J Vitam Nutr Res 78:195-203. 2008
    ....
  2. ncbi Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells
    Keiko Yamada
    Department of Liberal Arts and Sciences, School of Health Sciences, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
    Biochem Biophys Res Commun 305:101-7. 2003
    ..The results suggest that DGKgamma negatively regulates macrophage differentiation through its catalytic action operating on the cytoskeleton...
  3. ncbi The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain
    Shin ichi Imai
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo, 060 8556, Japan
    Biochem J 382:957-66. 2004
    ..Our results provide evidence of the phosphorylation of the DGKdelta1 PH domain by cPKC, and suggest that the phosphorylation is involved in the control of subcellular localization of DGKdelta1...
  4. ncbi Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation
    Shuichi Tsushima
    Department of Biochemistry, Sapporo Medical University School of Medicine, South 1 West 17, Chuo Ku, Sapporo 060 8556, Japan
    J Biol Chem 279:28603-13. 2004
    ..Taken together, these results strongly suggest that DGKgamma functions through its catalytic action as an upstream suppressor of Rac1 and, consequently, lamellipodium/ruffle formation...
  5. ncbi Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation
    Kenji Yanagisawa
    Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan
    Biochim Biophys Acta 1771:462-74. 2007
    ..Together, these results strongly suggest that DGKalpha is a novel positive regulator of NF-kappaB, which suppresses TNF-alpha-induced melanoma cell apoptosis...
  6. ncbi Analyses of non-leucine-rich repeat (non-LRR) regions intervening between LRRs in proteins
    Norio Matsushima
    Sapporo Medical University Center for Medical Education, Sapporo, Hokkaido 060 8556, Japan
    Biochim Biophys Acta 1790:1217-37. 2009
    ..Many proteins have LRR (leucine-rich repeat) units interrupted by non-LRRs which we call IR (non-LRR island region)...
  7. ncbi Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions
    Fumio Sakane
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
    J Biol Chem 277:43519-26. 2002
    ..Taken together, alternative splicing of the human DGKdelta gene generates at least two isoforms, differing in their expressions and regulatory functions...
  8. ncbi Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
    Norio Matsushima
    School of Health Sciences, Sapporo Medical University, Hokkaido, Japan
    BMC Genomics 8:124. 2007
    ..The repeat numbers of LRRs and their "phasing" in TLRs differ with isoforms and species; they are aligned differently in various databases. We identified and aligned LRRs in TLRs by a new method described here...
  9. ncbi Diacylglycerol kinases: emerging downstream regulators in cell signaling systems
    Hideo Kanoh
    Department of Biochemistry, School of Medicine, Sapporo Medical University, South West 17, Sapporo 060 8556, Japan
    J Biochem 131:629-33. 2002
    ....
  10. ncbi Copper binding to plant ozone-inducible proteins (OI2-2 and OI14-3)
    Masakatsu Kamiya
    Division of Biological Sciences, Graduate School of Science, Hokkaido University, 060 0810, Sapporo, Japan
    Biochem Biophys Res Commun 314:908-15. 2004
    ..Thus, the ozone-inducible proteins are capable of binding at least four or five copper ions per protein. These copper-binding proteins would function as active oxygen scavengers...