Toru Mizuguchi

Summary

Affiliation: Sapporo Medical University
Country: Japan

Publications

  1. doi request reprint Preoperative liver function assessments to estimate the prognosis and safety of liver resections
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    Surg Today 44:1-10. 2014
  2. doi request reprint Prognosis and predictors of surgical complications in hepatocellular carcinoma patients with or without cirrhosis after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    World J Surg 37:1379-87. 2013
  3. doi request reprint Serum antithrombin III level is well correlated with multiple indicators for assessment of liver function and diagnostic accuracy for predicting postoperative liver failure in hepatocellular carcinoma patients
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Hokkaido, Japan
    Hepatogastroenterology 59:551-7. 2012
  4. ncbi request reprint Serum hyaluronate level for predicting subclinical liver dysfunction after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, 060 8543, Sapporo, Hokkaido, Japan
    World J Surg 28:971-6. 2004
  5. doi request reprint Prognostic impact of surgical complications and preoperative serum hepatocyte growth factor in hepatocellular carcinoma patients after initial hepatectomy
    Toru Mizuguchi
    Department of Surgery I, School of Medicine, Sapporo Medical University, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    J Gastrointest Surg 13:325-33. 2009
  6. ncbi request reprint Rapid recovery of postoperative liver function after major hepatectomy using saline-linked electric cautery
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    Hepatogastroenterology 55:2188-92. 2008
  7. ncbi request reprint In situ graft-trimming method using polyester vascular prosthesis for inferior vena cava reconstruction after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Japan
    Dig Surg 23:115-8. 2006
  8. ncbi request reprint Hyperbaric oxygen stimulates cell proliferation and normalizes multidrug resistance protein-2 protein localization in primary rat hepatocytes
    Toru Mizuguchi
    Department of Surgery I, Cancer Research Institute, Sapporo Medical University School of Medicine, Sapporo, Japan
    Wound Repair Regen 13:551-7. 2005
  9. doi request reprint Prognostic impact of preoperative the branched-chain amino acid to the tyrosine ratio in hepatocellular carcinoma patients after initial hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido, 060 8543, Japan
    J Gastrointest Surg 15:1433-9. 2011
  10. ncbi request reprint Successful management of severe acute pancreatitis with multiple organ failure
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
    Pancreas 28:211-3. 2004

Collaborators

Detail Information

Publications48

  1. doi request reprint Preoperative liver function assessments to estimate the prognosis and safety of liver resections
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    Surg Today 44:1-10. 2014
    ..Imaging modalities such as (99m)Tc-galactosyl serum albumin scintigraphy, (99m)Tc-mebrofenin hepatobiliary scintigraphy and transient elastography are also available, but future studies are needed to validate their clinical efficacy. ..
  2. doi request reprint Prognosis and predictors of surgical complications in hepatocellular carcinoma patients with or without cirrhosis after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    World J Surg 37:1379-87. 2013
    ..The purpose of this study was to assess how the liver pathology of HCC patients affects their prognosis and complications rate after liver resection...
  3. doi request reprint Serum antithrombin III level is well correlated with multiple indicators for assessment of liver function and diagnostic accuracy for predicting postoperative liver failure in hepatocellular carcinoma patients
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Hokkaido, Japan
    Hepatogastroenterology 59:551-7. 2012
    ....
  4. ncbi request reprint Serum hyaluronate level for predicting subclinical liver dysfunction after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, 060 8543, Sapporo, Hokkaido, Japan
    World J Surg 28:971-6. 2004
    ..Furthermore, patients with a significantly low HGF level who have a normal HA level are susceptible to liver dysfunction after hepatectomy...
  5. doi request reprint Prognostic impact of surgical complications and preoperative serum hepatocyte growth factor in hepatocellular carcinoma patients after initial hepatectomy
    Toru Mizuguchi
    Department of Surgery I, School of Medicine, Sapporo Medical University, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    J Gastrointest Surg 13:325-33. 2009
    ....
  6. ncbi request reprint Rapid recovery of postoperative liver function after major hepatectomy using saline-linked electric cautery
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    Hepatogastroenterology 55:2188-92. 2008
    ..The purpose of this study was to compare postoperative liver function after major liver resection using an argon laser beam coagulator (AR) and that using saline-linked electric cautery (SLC) for vessels and bile duct sealing...
  7. ncbi request reprint In situ graft-trimming method using polyester vascular prosthesis for inferior vena cava reconstruction after hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Japan
    Dig Surg 23:115-8. 2006
    ..The in situ graft-trimming method is an easy and safe method to ensure the correct graft size after IVC reconstruction...
  8. ncbi request reprint Hyperbaric oxygen stimulates cell proliferation and normalizes multidrug resistance protein-2 protein localization in primary rat hepatocytes
    Toru Mizuguchi
    Department of Surgery I, Cancer Research Institute, Sapporo Medical University School of Medicine, Sapporo, Japan
    Wound Repair Regen 13:551-7. 2005
    ..These results show that HBO stimulates hepatocytes to proliferate and HBO normalizes multidrug resistance protein-2 localization to the apical membrane, which could dilate bile canaliculi...
  9. doi request reprint Prognostic impact of preoperative the branched-chain amino acid to the tyrosine ratio in hepatocellular carcinoma patients after initial hepatectomy
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido, 060 8543, Japan
    J Gastrointest Surg 15:1433-9. 2011
    ..Furthermore, we evaluated the clinical usefulness of BTR as a prognostic indicator of disease-free and overall patient survival after initial hepatectomy...
  10. ncbi request reprint Successful management of severe acute pancreatitis with multiple organ failure
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
    Pancreas 28:211-3. 2004
  11. ncbi request reprint Assessment of nutritional status and prediction of postoperative liver function from serum apolioprotein A-1 levels with hepatectomy
    Tadashi Katsuramaki
    First Department of Surgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo, Japan
    World J Surg 30:1886-91. 2006
    ..We investigated the usefulness of apolipoprotein A-1 (apoA) as an indicator of nutritional status, and the correlation of the preoperative apoA level with changes in postoperative liver function following hepatectomy...
  12. doi request reprint In vitro transformation of adult rat hepatic progenitor cells into pancreatic endocrine hormone-producing cells
    Hiroyuki Kawasaki
    First Department of Surgery, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    J Hepatobiliary Pancreat Surg 15:310-7. 2008
    ..Our goal in this study was to see if small hepatocytes (SHs) could give rise to pancreatic endocrine cells via exogenous Pdx-1 gene expression...
  13. ncbi request reprint Assessment of liver fibrosis by a noninvasive method of transient elastography and biochemical markers
    Masaki Kawamoto
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    World J Gastroenterol 12:4325-30. 2006
    ....
  14. doi request reprint Efficient transformation of small hepatocytes into insulin-expressing cells by forced expression of Pdx1
    Hiroyuki Kawasaki
    Department of Surgery I, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    J Hepatobiliary Pancreat Surg 15:403-9. 2008
    ..The focus of our study was to compare the efficacy of the transformation into pancreatic endocrine cells of SHs and mature hepatocytes (MHs)...
  15. ncbi request reprint Liver repopulation and long-term function of rat small hepatocyte transplantation as an alternative cell source for hepatocyte transplantation
    Chihiro Shibata
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo, Hokkaido, Japan
    Liver Transpl 12:78-87. 2006
    ..These observations strongly support the idea that SHs could be an alternative to primary FHs as a novel cell source for future HT...
  16. doi request reprint Cluster analysis of indicators of liver functional and preoperative low branched-chain amino acid tyrosine ration indicate a high risk of early recurrence in analysis of 165 hepatocellular carcinoma patients after initial hepatectomy
    Yukio Nakamura
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
    Surgery 150:250-62. 2011
    ..We developed the ALB-BTR and HGF-BTR classifications depending on each level to find specific unique subgroups. Our aim was to identify specific subgroups destined for favorable and poor prognoses after initial hepatectomy...
  17. pmc Low-dose steroid pretreatment ameliorates the transient impairment of liver regeneration
    Toshihito Shibata
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo, Hokkaido 060 8543, Japan
    World J Gastroenterol 18:905-14. 2012
    ..To determine if liver regeneration (LR) could be disturbed following radiofrequency (RF) ablation and whether modification of LR by steroid administration occurs...
  18. doi request reprint Impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice
    Takayuki Nobuoka
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Japan
    Liver Int 29:979-87. 2009
    ..However, the role of UTI in LR is totally unknown. The aim of this study was to elucidate the role of UTI in LR using genetically UTI-deficient mice...
  19. ncbi request reprint Serum lipid and lipoprotein alterations represent recovery of liver function after hepatectomy
    Masaki Kawamoto
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
    Liver Int 26:203-10. 2006
    ..We selected patients prospectively and measured serum lipid and lipoprotein levels to identify which lipids and lipoproteins could represent recovery of liver function in human liver regeneration...
  20. doi request reprint Continuous monitoring of central venous oxygen saturation predicts postoperative liver dysfunction after liver resection
    Makoto Meguro
    Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, Hokkaido, Japan
    Surgery 154:351-62. 2013
    ..We examined whether the data obtained by monitoring central venous oxygen saturation (ScvO2) and/or stroke volume variation (SVV) during hepatectomy, as measured with the FloTrac/Vigileo system, can predict postoperative liver dysfunction...
  21. doi request reprint Area between the hepatic and heart curves of (99m)Tc-galactosyl-human serum albumin scintigraphy represents liver function and disease progression for preoperative evaluation in hepatocellular carcinoma patients
    Kohei Harada
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    J Hepatobiliary Pancreat Sci 19:667-73. 2012
    ..The aim of this study was to examine the accuracy of the ABC to evaluate liver function before hepatectomy...
  22. doi request reprint Laparoscopic hepatectomy: a systematic review, meta-analysis, and power analysis
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    Surg Today 41:39-47. 2011
    ..The aim of the present study was to re-evaluate perioperative variables and adverse outcomes in patients undergoing Lap versus (vs) Op after 2000...
  23. doi request reprint Differentiation capacity of hepatic stem/progenitor cells isolated from D-galactosamine-treated rat livers
    Norihisa Ichinohe
    Department of Tissue Development and Regeneration, the Research Institute for Frontier Medicine, Sapporo, Japan
    Hepatology 57:1192-202. 2013
    ..hepatology 2013)...
  24. doi request reprint Effects of a low-fat meal on the oral bioavailability of UFT and leucovorin in patients with colorectal cancer
    Tomohisa Furuhata
    First Department of Surgery, Sapporo Medical University, South 1 West 16, Chuo Ku, Sapporo 060 8543, Japan
    Int J Clin Oncol 14:529-33. 2009
    ....
  25. pmc Vascular endothelial growth factor 165b expression in stromal cells and colorectal cancer
    Makoto Tayama
    The First Department of Surgery, Sapporo Medical University, South 1, West 16, Chuo Ku, Sapporo 060 8543, Japan
    World J Gastroenterol 17:4867-74. 2011
    ..To characterize the implications of vascular endothelial growth factor (VEGF)-A in stromal cells and colorectal cancer and the expression of VEGF-A splice variants...
  26. ncbi request reprint New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis
    Hitoshi Kikuchi
    Department of Surgery section 1, Sapporo Medical University School of Medicine, Chuo Ku, Sapporo, Japan
    Wound Repair Regen 15:881-8. 2007
    ..This oral iNOS inhibitor will be a new strategy for the treatment of cirrhosis...
  27. ncbi request reprint Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer
    Yoshiko Inafuku
    Sapporo Medical University, First Department of Surgery, 060 8543 South 1 West 16 Chuo ku, Sapporo, Japan
    Cancer Sci 100:852-8. 2009
    ..In conclusion, these findings suggest that matrix metalloproteinase-2 expression in stromal cells can be a high-risk indicator for recurrence in patients with stage II colon cancer...
  28. doi request reprint Prospective nonrandomized comparison between pylorus-preserving and subtotal stomach-preserving pancreaticoduodenectomy from the perspectives of DGE occurrence and postoperative digestive functions
    Emi Akizuki
    Department of Surgical Oncology and Gastroenterological Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060 8543, Japan
    J Gastrointest Surg 12:1185-92. 2008
    ..To determine the influence of pylorus preservation after pancreaticoduodenectomy, we compared the postoperative course of subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) and pylorus-preserving pancreaticoduodenectomy (PPPD)...
  29. doi request reprint Clinical compliance with an oral uracil/tegafur (UFT) plus leucovorin (LV) regimen as adjuvant chemotherapy in Japanese colorectal cancer patients
    Makoto Meguro
    Department of Surgical Oncology and Gastroenterological Surgery, Sapporo Medical University School of Medicine, Chuo Ku, Sapporo, Japan
    Int J Clin Oncol 14:402-7. 2009
    ..However, the clinical compliance of Japanese patients with this regimen has not been clearly elucidated to date...
  30. ncbi request reprint Hepatocyte transplantation for total liver repopulation
    Toru Mizuguchi
    Department of Surgery I, Sapporo Medical University Hospital, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    J Hepatobiliary Pancreat Surg 12:378-85. 2005
    ..HT may become an alternative for liver transplantation in the future; however, many efforts should made before establishing an effective method for HT and liver replacement therapy...
  31. ncbi request reprint Proliferation of hepatocyte progenitor cells isolated from adult human livers in serum-free medium
    Kazunori Sasaki
    Department of Pathophysiology, Cancer Research Institute, Sapporo Medical University School of Medicine, Sapporo 060 8556, Japan
    Cell Transplant 17:1221-30. 2008
    ..Human SHs may be a useful source for cell transplantation as well as pharmaceutical and toxicological investigations...
  32. ncbi request reprint Progression and regression of biloma after laparoscopic cholecystectomy evaluated by computed tomography
    Masaaki Ishikawa
    Department of Surgery, Dohtoh Hospital, Kushiro, Hokkaido, Japan
    Int Surg 90:137-40. 2005
    ..Therefore, it is not always necessary to carry out treatment for biloma after LC if the patient has no symptoms. This is the first report that shows the progression and regression of biloma evaluated precisely by CT...
  33. pmc Pancreaticoduodenectomy for biliary tract carcinoma with situs inversus totalis: difficulties and technical notes based on two cases
    Daisuke Kyuno
    Departments of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, 1 South, 16 West, Chuo Ku, Sapporo 060 8543, Japan
    World J Surg Oncol 11:312. 2013
    ..Pancreaticoduodenectomy in patients with SIT can be performed successfully with detailed preoperative assessment, use of effective techniques by the surgeon, and appropriate support by assistants. ..
  34. ncbi request reprint Biliary injury after laparoscopic cholecystectomy: end-to-end anastomosis covered with umbilical vein
    Yasutoshi Kimura
    First Department of Surgery, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido, 060 8543, Japan
    J Hepatobiliary Pancreat Surg 12:269-71. 2005
    ..This procedure may be a promising reinforcement of the reconstructed site which maintains the biliary integrity; however, it can be applied, only in selected situations...
  35. ncbi request reprint Current status of surgery for pancreatic cancer
    Koichi Hirata
    Department of Gastrointestinal Surgery and Oncological Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan
    Dig Surg 24:137-47. 2007
    ..Therefore, an adequate comparison and analysis of the data from Japan, Europe and the USA is required. This review evaluates many important published reports from Japan which influence surgical procedure...
  36. doi request reprint Hepatic biliary epithelial cells acquire epithelial integrity but lose plasticity to differentiate into hepatocytes in vitro during development
    Naoki Tanimizu
    Department of Tissue Development and Regeneration, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, S 1, W 17, Chuo Ku, Sapporo, Japan
    J Cell Sci 126:5239-46. 2013
    ..Our results suggest that a molecular machinery augmenting epithelial integrity limits lineage plasticity of epithelial cells...
  37. ncbi request reprint Biliary tract malignancy and chronic inflammation from the perspective of pancreaticobiliary maljunction
    Yasutoshi Kimura
    Department of Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan
    Oncology 69:41-5. 2005
    ..Knowledge on molecular pathogenesis is gradually increasing. However, studies should be expanded to include larger patient cohorts, and other types of molecules should be carefully investigated and analyzed...
  38. ncbi request reprint Hand-assisted laparoscopic pylorus-preserving pancreaticoduodenectomy for pancreas head disease
    Yasutoshi Kimura
    First Department of Surgery, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    Am J Surg 189:734-7. 2005
    ..To overcome the shortcomings, we developed the first hand-assisted laparoscopic pylorus-preserving PD and, in this report, present the case of a patient with a low-grade malignant tumor on the pancreas head...
  39. ncbi request reprint Endo-bowel clamp (PL540S) for safe rectal irrigation in laparoscopy-assisted rectal resection
    Tomohisa Furuhata
    First Department of Surgery, Sapporo Medical University, School of Medicine, S 1, W 16, Chuo Ku, Sapporo 060 8543, Japan
    Surg Today 34:882-4. 2004
    ..By placing a PL540S before transection, it is possible to occlude the rectum completely and irrigate it effectively. We think that the PL540S is a valuable device in laparoscopic surgery for rectal cancer...
  40. ncbi request reprint [Present status and future prospects of nutritional support teams]
    Koichi Hirata
    Committee of NST, Sapporo Medical University Hospital, Sapporo, Japan
    Nihon Geka Gakkai Zasshi 111:341-7. 2010
    ..It will be necessary to the revise the assessment of NSTs as proposed by a committee of the Japanese Nutritional Support Promotion Group or to carry out surveillance to evaluate the outcomes of NST activity...
  41. pmc The molecular pathogenesis and clinical implications of hepatocellular carcinoma
    Makoto Meguro
    Department of Surgical Oncology and Gastroenterological Surgery, Sapporo Medical University School of Medicine, S 1, W 16, Chuo Ku, Sapporo, Hokkaido 060 8543, Japan
    Int J Hepatol 2011:818672. 2011
    ..In this review, we describe the molecular pathogenesis and the current state and future development of molecular- and CSC-therapeutic targeted agents for HCC, citing various reports...
  42. ncbi request reprint Immediate early genes and p21 regulation in liver of rats with acute hepatic failure
    Thomas T Hui
    Liver Support Research Laboratory, Department of Surgery, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Am J Surg 183:457-63. 2002
    ..In contrast, p21 mRNA and protein are both over-expressed in AHF livers compared to livers from rats undergoing PH; this elevation leads to inhibition in Cdk2 activity, resulting in G1 cell cycle arrest and inhibition of regeneration...
  43. ncbi request reprint Growth of hepatic angiomyolipoma indicating malignant potential
    Toru Mizuguchi
    J Gastroenterol Hepatol 19:1328-30. 2004
  44. ncbi request reprint A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration
    Kozo Akino
    Department of Medicine, Cedars Sinai Research Institute UCLA School of Medicine, Los Angeles, California, USA
    J Surg Res 129:142-6. 2005
    ..Because the liver is a regenerative organ, the relevant biological function of PTTG in the liver would be more feasible to understand PTTG. Also, PTTG may be involved in the liver regeneration...
  45. ncbi request reprint Glycerol suppresses proliferation of rat hepatocytes and human HepG2 cells
    Nozomu Sugiyama
    The Liver Support Research Laboratory, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Surg Res 103:236-42. 2002
    ..Additionally, we investigated the effect of glycerol on the proliferation of HepG2 cells...
  46. doi request reprint Laminin alpha 5 mediates ectopic adhesion of hepatocellular carcinoma through integrins and/or Lutheran/basal cell adhesion molecule
    Yamato Kikkawa
    Laboratory of Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji 192 0392, Japan
    Exp Cell Res 314:2579-90. 2008
    ..These results suggest that laminins containing alpha 5 serve as functional substrates regulating progression of HCC...
  47. ncbi request reprint Effects of bone marrow stromal cells on the structural and functional polarity of primary rat hepatocytes
    Toru Mizuguchi
    In Vitro Cell Dev Biol Anim 38:62-5. 2002
  48. ncbi request reprint Hepatic organoid formation in collagen sponge of cells isolated from human liver tissues
    Shinichi Sugimoto
    Department of Gastroenterological Surgery, Kyoto University Graduate School of Medicine, Japan
    Tissue Eng 11:626-33. 2005
    ..The cells in the collagen sponge actively proliferated and the hepatocytes excreted albumin into the medium. Thus, hepatic organoids could be reconstructed in a collagen sponge by normal human liver cells...