Research Topics
| H TakeiSummaryAffiliation: Saitama Cancer Center Country: Japan Publications
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Detail Information
Publications
99mTc-phytate is better than 99mTc-human serum albumin as a radioactive tracer for sentinel lymph node biopsy in breast cancerHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina-machi, Kitaadachi, Saitama, 362-0806, Japan
Surg Today 36:219-24. 2006..Thus, 99mTc-phytate is better than 99mTc-HSA as a radioactive agent for SLNB in breast cancer...
Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-Hiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
Breast Cancer Res Treat 133:227-36. 2012..Given the results of the TEAM trial, upfront use of tamoxifen followed by an aromatase inhibitor (AI) may be an important option for adjuvant endocrine therapy in Japanese postmenopausal women...- Neoadjuvant endocrine therapy of breast cancer: which patients would benefit and what are the advantages?Hiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina, Kita adachi, Saitama, Japan
Breast Cancer 18:85-91. 2011..Indeed, neoadjuvant AIs are a potential treatment option for postmenopausal women with ER-rich breast cancer who prefer BCS despite having large tumors suitable for mastectomy... - Axillary lymph node dissection can be avoided in women with breast cancer with intraoperative, false-negative sentinel lymph node biopsiesHiroyuki Takei
Saitama Cancer Center, Komuro Ina, Kita adachi, Japan
Breast Cancer 17:9-16. 2010..It is currently unclear which patients with breast cancer with sentinel lymph node (SLN) metastases do not need axillary lymph node dissection (ALND)... - Positive sentinel lymph node biopsy predicts the number of metastatic axillary nodes of breast cancerHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
Breast 18:244-7. 2009..The numbers of positive and negative SLNs can predict the number of metastatic axillary nodes in breast cancer patients... - Current trends of sentinel lymph node biopsy for breast cancer--a surgeon's perspectiveHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, 362 0806, Japan
Breast Cancer 14:362-70. 2007.... - Recurrence after sentinel lymph node biopsy with or without axillary lymph node dissection in patients with breast cancerHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, Saitama, Japan
Breast Cancer 14:16-24. 2007..A regional nodal recurrence is a major concern after a sentinel lymph node biopsy (SLNB) alone in patients with breast cancer. In this study we investigated patterns and risk factors of regional nodal recurrence after SLNB alone... - Sentinel lymph node biopsy alone has no adverse impact on the survival of patients with breast cancerHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
Breast J 12:S157-64. 2006..As the type of axillary surgery had no impact on the prognosis of patients with breast cancer, a SLNB alone is safe as determined by a negative histologic investigation... - Added value of the presence of blue nodes or hot nodes in sentinel lymph node biopsy of breast cancerHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, Kitaadachi, Japan
Breast Cancer 13:179-85. 2006..Combined use of blue dye and radiocolloid is considered to be useful for sentinel lymph node (SLN) biopsy of breast cancer. Whether both techniques together is superior to either alone was analyzed... - Predictive value of estrogen receptor status as assessed by ligand-binding assay in patients with early-stage breast cancer treated with breast conserving surgery and radiation therapyH Takei
Division of Breast Surgery, Saitama Cancer Center, Ina machi, Kitaadachi gun, Saitama 362 0806, Japan
Oncol Rep 9:375-8. 2002..As a result, we believe that ER measured by LBA is valuable for predicting prognosis of early-stage breast cancer patients treated with BCS and RT... - Sentinel lymph node biopsy without axillary dissection after an intraoperative negative histological investigation in 358 invasive breast cancer casesHiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, 818 Ina machi, Kitaadachi, Saitama 362 0806, Japan
Breast Cancer 9:344-8. 2002..The present study shows the results and outcomes of SLNB as a sole procedure for patients with invasive breast cancer... - True recurrences and new primary tumors have different clinical features in invasive breast cancer patients with ipsilateral breast tumor relapse after breast-conserving treatmentTakashi Yoshida
Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
Breast J 16:127-33. 2010..The overall survival after IBTR was worse in patients with TR than NPT. TR and NPT show quite different clinical features. Classifying IBTR into TR or NPT can therefore help to select the most appropriate treatment for IBTR... - Ipsilateral breast tumor relapse after breast conserving surgery in women with breast cancerTakashi Yoshida
Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina, Kita adachi, Saitama 362 0806, Japan
Breast 18:238-43. 2009..9% in patients with IBTR and 93.2% in patients without IBTR. In order to prevent IBTR, a negative margin and the administration of RT are therefore considered to be important in patients who undergo BCS... - Significance and problems of histopathological examination and utility of real-time reverse transcriptase-polymerase chain reaction method for the detection of sentinel lymph node metastasis in breast cancerMasafumi Kurosumi
Department of Pathology Saitama Cancer Center, Saitama 362 0806, Japan
Breast Cancer 14:342-9. 2007..2 mm) (sensitivity and specificity; 89.5% and 96.7% frozen sections) and expected to be used as a routine method instead of histopathological examination... - Tumor-stromal interaction through the estrogen-signaling pathway in human breast cancerYuri Yamaguchi
Research Institute for Clinical Oncology, Saitama Cancer Center, Japan
Cancer Res 65:4653-62. 2005..These results suggest that this system to detect total ER activation based on the interaction with adipose stromal cells is a useful tool for analyzing local estrogen signals and for tumor-stromal interactions... - Prognostic significance of scoring system based on histological heterogeneity of invasive ductal carcinoma for node-negative breast cancer patientsMasafumi Kurosumi
Department of Pathology, Saitama Cancer Center, 818 Komuro, Ina machi, Kitaadachi gun, Saitama 362 0806, Japan
Oncol Rep 10:833-7. 2003.... - Immunohistochemical study of the relationship between Ki-67 labeling index of proliferating cells of gynecomastia, histological phase and duration of diseaseSeishi Kono
Department of Pathology, Saitama Cancer Center, Ina-machi, Saitama, Japan
Pathol Int 56:655-8. 2006..041): the shorter the duration the higher the Ki-67 LI. Thus, Ki-67 LI seems a useful tool to examine proliferation activity of gynecomastia and can assist in determination of appropriate treatment of gynecomastia with hormonal therapy... - Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03)Hiroyuki Takei
Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
Breast Cancer Res Treat 107:87-94. 2008..Further studies are required to determine the optimal duration of neoadjuvant treatment and to identify response criteria that can more accurately predict long-term outcomes... - [Clinicopathological characteristics of familial breast cancer]Mari Kamimura
Division of Breast Surgery, Saitama Cancer Center
Nippon Rinsho 65:607-9. 2007 - Nipple adenoma found in a mastectomy specimen: report of a case with special regard to the proliferation patternSeishi Kono
Department of Pathology, Saitama Cancer Center, Japan
Breast Cancer 14:234-8. 2007.... - [Tolerability and safety of docetaxel plus cyclophosphamide as adjuvant chemotherapy for axillary lymph node-negative breast cancer--JECBC04 trial]Naohito Yamamoto
Chiba Cancer Center, Division of Breast Surgery, Chiba, Japan
Gan To Kagaku Ryoho 37:57-63. 2010..The grade 3/4 toxicity including leukopenia, neutropenia, and febrile neutropenia was manageable. From these results, we consider that TC might become a standard non-anthracycline adjuvant regimen for operable breast cancer... - Breast-conserving therapy versus modified radical mastectomy in the treatment of early breast cancer in JapanJun Horiguchi
Second Department of Surgery, Gunma University Faculty of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
Breast Cancer 9:160-5. 2002..Breast-conserving therapy has been widely utilized as a treatment option for women with early breast cancer. However, no randomized study comparing modified radical mastectomy and breast-conserving therapy has been conducted in Japan... - Breast-conserving surgery following radiation therapy of 50 Gy in stages I and II carcinoma of the breast: the experience at one institute in JapanJun Horiguchi
Second Department of Surgery, Gunma University Faculty of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
Oncol Rep 9:1053-7. 2002..Local recurrence however, has no adverse effect on survival of patients... - DPD activity and immunohistochemical DPD expression in human breast cancerJun Horiguchi
Second Department of Surgery, Gunma University Faculty of Medicine, Gunma 371 8511, Japan
Oncol Rep 11:65-72. 2004..In conclusion, DPD expression may function as a marker of DPD activity and may be a prognostic indicator for patients with breast cancer... - Estrogen signaling ability in human endometrial cancer through the cancer-stromal interactionMitsuyo Matsumoto
Department of Medical Technology, Tohoku University School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai 981 0872, Japan
Endocr Relat Cancer 15:451-63. 2008..These results suggest that AI may have some therapeutic value in EC; however, the hormonal microenvironment must be assessed prior to initiating therapy... - Human leukocyte antigen as a predictive factor of developing bilateral breast cancer in Japanese womenTakao Yokoe
Department of Surgery, Shibukawa General Hospital, Gunma University Graduate School of Medicine, Gunma, Japan
Breast J 12:S201-3. 2006..The risk of bilateral breast cancer in patients with haplotype A24 and Cw7 is 12 times higher compared with those without the haplotype. HLA typing is useful for selecting patients who are at high risk of contralateral breast cancer... - The prevalence of intrinsic subtypes and prognosis in breast cancer patients of different racesJunichi Kurebayashi
Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
Breast 16:S72-7. 2007..The prevalence of intrinsic subtypes should be taken into account when analyzing survival data in a multi-racial/international clinical study... - [Multicenter phase II trial of thrice-weekly docetaxel and weekly trastuzumab as preoperative chemotherapy in patients with HER 2-overexpressing breast cancer--Japan East Cancer Center Breast Cancer Consortium (JECBC) 02 Trial]Muneaki Sano
Dept. of Surgery, Niigata Cancer Center Hospital
Gan To Kagaku Ryoho 33:1411-5. 2006..This regimen promises to be one of the leading future treatments for progressive breast cancer... - A mechanism of drug resistance to tamoxifen in breast cancerJennifer MacGregor Schafer
Robert H. Lurie Comprehensive Cancer Center, The Feinberg School of Medicine, Northwestern University, Olson Pavilion 8258, 303 East Chicago Avenue, Chicago, IL 60611, USA
J Steroid Biochem Mol Biol 83:75-83. 2002..Three phases of tumor progression are described that involve increases in HER-2/neu expression, de-regulation of estrogen receptor expression and increases in apoptosis which in concert determine the phenotype of drug resistance to Tam... - In vitro regulation of vascular endothelial growth factor by estrogens and antiestrogens in estrogen-receptor positive breast cancerHiroyuki Takei
Northwestern University Medical School, Robert H Lurie Comprehensive Cancer Center, USA
Breast Cancer 9:39-42. 2002..In this study we investigated the in vitro effects of antiestrogens at different concentrations on vascular endothelial growth factor (VEGF) production in estrogen receptor (ER)-positive breast cancer cells... - Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumorsSatoshi Hirasawa
Department of Diagnostic and Interventional Radiology, Gunma Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
Acad Radiol 14:312-8. 2007..We sought to determine the relationship between tumor blood flow and glucose uptake in head and neck tumors using perfusion computed tomography (PCT) and fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET)... - The regulatory effect of tamoxifen on fibronectin expression in estrogen-dependent MCF-7 breast carcinoma cellsYoshio Horii
Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
Oncol Rep 15:1191-5. 2006..These results suggest that TAM increases FN expression of MCF-7 breast carcinoma cells and that these regulatory effects of TAM on FN expression are partly mediated by TAM-induced TGF-beta... - Perfusion CT of breast carcinoma: arterial perfusion of nonscirrhous carcinoma was higher than that of scirrhous carcinomaHiromi Hirasawa
Department of Diagnostic and Interventional Radiology, Gunma Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
Acad Radiol 14:547-52. 2007..Our goals were to apply perfusion CT technique to breast tumor and to evaluate the correlation between arterial perfusion value and other tumor characteristics...