H Takei

Summary

Affiliation: Saitama Cancer Center
Country: Japan

Publications

  1. ncbi request reprint 99mTc-phytate is better than 99mTc-human serum albumin as a radioactive tracer for sentinel lymph node biopsy in breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina machi, Kitaadachi, Saitama, 362 0806, Japan
    Surg Today 36:219-24. 2006
  2. pmc Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemot
    Mamoru Takada
    Department of Cancer Diagnosis, Research Institute for Clinical Oncology, Saitama Cancer Center, 818 Komuro, Ina, Saitama, 362 0806, Japan
    BMC Cancer 13:241. 2013
  3. doi request reprint Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
    Breast Cancer Res Treat 133:227-36. 2012
  4. ncbi request reprint Sentinel lymph node biopsy alone has no adverse impact on the survival of patients with breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
    Breast J 12:S157-64. 2006
  5. ncbi request reprint Recurrence after sentinel lymph node biopsy with or without axillary lymph node dissection in patients with breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Saitama, Japan
    Breast Cancer 14:16-24. 2007
  6. ncbi request reprint Predictive value of estrogen receptor status as assessed by ligand-binding assay in patients with early-stage breast cancer treated with breast conserving surgery and radiation therapy
    H Takei
    Division of Breast Surgery, Saitama Cancer Center, Ina machi, Kitaadachi gun, Saitama 362 0806, Japan
    Oncol Rep 9:375-8. 2002
  7. ncbi request reprint Current trends of sentinel lymph node biopsy for breast cancer--a surgeon's perspective
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, 362 0806, Japan
    Breast Cancer 14:362-70. 2007
  8. doi request reprint Positive sentinel lymph node biopsy predicts the number of metastatic axillary nodes of breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
    Breast 18:244-7. 2009
  9. doi request reprint Axillary lymph node dissection can be avoided in women with breast cancer with intraoperative, false-negative sentinel lymph node biopsies
    Hiroyuki Takei
    Saitama Cancer Center, Komuro Ina, Kita adachi, Japan
    Breast Cancer 17:9-16. 2010
  10. doi request reprint Neoadjuvant endocrine therapy of breast cancer: which patients would benefit and what are the advantages?
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina, Kita adachi, Saitama, Japan
    Breast Cancer 18:85-91. 2011

Collaborators

Detail Information

Publications34

  1. ncbi request reprint 99mTc-phytate is better than 99mTc-human serum albumin as a radioactive tracer for sentinel lymph node biopsy in breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina machi, Kitaadachi, Saitama, 362 0806, Japan
    Surg Today 36:219-24. 2006
    ..We retrospectively compared the effectiveness of two radioactive agents, 99mTc-phytate and 99mTc-human serum albumin (HSA), when used in combination with blue dye...
  2. pmc Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemot
    Mamoru Takada
    Department of Cancer Diagnosis, Research Institute for Clinical Oncology, Saitama Cancer Center, 818 Komuro, Ina, Saitama, 362 0806, Japan
    BMC Cancer 13:241. 2013
    ..The mechanisms of recurrence and biomarkers that indicate the response to the chemotherapy and outcome are not fully investigated...
  3. doi request reprint Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
    Breast Cancer Res Treat 133:227-36. 2012
    ..Given the results of the TEAM trial, upfront use of tamoxifen followed by an aromatase inhibitor (AI) may be an important option for adjuvant endocrine therapy in Japanese postmenopausal women...
  4. ncbi request reprint Sentinel lymph node biopsy alone has no adverse impact on the survival of patients with breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
    Breast J 12:S157-64. 2006
    ..As the type of axillary surgery had no impact on the prognosis of patients with breast cancer, a SLNB alone is safe as determined by a negative histologic investigation...
  5. ncbi request reprint Recurrence after sentinel lymph node biopsy with or without axillary lymph node dissection in patients with breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Saitama, Japan
    Breast Cancer 14:16-24. 2007
    ..A regional nodal recurrence is a major concern after a sentinel lymph node biopsy (SLNB) alone in patients with breast cancer. In this study we investigated patterns and risk factors of regional nodal recurrence after SLNB alone...
  6. ncbi request reprint Predictive value of estrogen receptor status as assessed by ligand-binding assay in patients with early-stage breast cancer treated with breast conserving surgery and radiation therapy
    H Takei
    Division of Breast Surgery, Saitama Cancer Center, Ina machi, Kitaadachi gun, Saitama 362 0806, Japan
    Oncol Rep 9:375-8. 2002
    ..As a result, we believe that ER measured by LBA is valuable for predicting prognosis of early-stage breast cancer patients treated with BCS and RT...
  7. ncbi request reprint Current trends of sentinel lymph node biopsy for breast cancer--a surgeon's perspective
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, 362 0806, Japan
    Breast Cancer 14:362-70. 2007
    ....
  8. doi request reprint Positive sentinel lymph node biopsy predicts the number of metastatic axillary nodes of breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro Ina, Kita adachi, Saitama 362 0806, Japan
    Breast 18:244-7. 2009
    ..The numbers of positive and negative SLNs can predict the number of metastatic axillary nodes in breast cancer patients...
  9. doi request reprint Axillary lymph node dissection can be avoided in women with breast cancer with intraoperative, false-negative sentinel lymph node biopsies
    Hiroyuki Takei
    Saitama Cancer Center, Komuro Ina, Kita adachi, Japan
    Breast Cancer 17:9-16. 2010
    ..It is currently unclear which patients with breast cancer with sentinel lymph node (SLN) metastases do not need axillary lymph node dissection (ALND)...
  10. doi request reprint Neoadjuvant endocrine therapy of breast cancer: which patients would benefit and what are the advantages?
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina, Kita adachi, Saitama, Japan
    Breast Cancer 18:85-91. 2011
    ..Indeed, neoadjuvant AIs are a potential treatment option for postmenopausal women with ER-rich breast cancer who prefer BCS despite having large tumors suitable for mastectomy...
  11. ncbi request reprint Added value of the presence of blue nodes or hot nodes in sentinel lymph node biopsy of breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kitaadachi, Japan
    Breast Cancer 13:179-85. 2006
    ..Combined use of blue dye and radiocolloid is considered to be useful for sentinel lymph node (SLN) biopsy of breast cancer. Whether both techniques together is superior to either alone was analyzed...
  12. ncbi request reprint Sentinel lymph node biopsy without axillary dissection after an intraoperative negative histological investigation in 358 invasive breast cancer cases
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Ina machi, Kitaadachi, Saitama 362 0806, Japan
    Breast Cancer 9:344-8. 2002
    ..The present study shows the results and outcomes of SLNB as a sole procedure for patients with invasive breast cancer...
  13. ncbi request reprint Significance and problems of histopathological examination and utility of real-time reverse transcriptase-polymerase chain reaction method for the detection of sentinel lymph node metastasis in breast cancer
    Masafumi Kurosumi
    Department of Pathology Saitama Cancer Center, Saitama 362 0806, Japan
    Breast Cancer 14:342-9. 2007
    ..2 mm) (sensitivity and specificity; 89.5% and 96.7% frozen sections) and expected to be used as a routine method instead of histopathological examination...
  14. doi request reprint Ipsilateral breast tumor relapse after breast conserving surgery in women with breast cancer
    Takashi Yoshida
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina, Kita adachi, Saitama 362 0806, Japan
    Breast 18:238-43. 2009
    ..9% in patients with IBTR and 93.2% in patients without IBTR. In order to prevent IBTR, a negative margin and the administration of RT are therefore considered to be important in patients who undergo BCS...
  15. doi request reprint True recurrences and new primary tumors have different clinical features in invasive breast cancer patients with ipsilateral breast tumor relapse after breast-conserving treatment
    Takashi Yoshida
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
    Breast J 16:127-33. 2010
    ..The overall survival after IBTR was worse in patients with TR than NPT. TR and NPT show quite different clinical features. Classifying IBTR into TR or NPT can therefore help to select the most appropriate treatment for IBTR...
  16. ncbi request reprint Prognostic significance of scoring system based on histological heterogeneity of invasive ductal carcinoma for node-negative breast cancer patients
    Masafumi Kurosumi
    Department of Pathology, Saitama Cancer Center, 818 Komuro, Ina machi, Kitaadachi gun, Saitama 362 0806, Japan
    Oncol Rep 10:833-7. 2003
    ....
  17. ncbi request reprint Tumor-stromal interaction through the estrogen-signaling pathway in human breast cancer
    Yuri Yamaguchi
    Research Institute for Clinical Oncology, Saitama Cancer Center, Japan
    Cancer Res 65:4653-62. 2005
    ..These results suggest that this system to detect total ER activation based on the interaction with adipose stromal cells is a useful tool for analyzing local estrogen signals and for tumor-stromal interactions...
  18. ncbi request reprint Immunohistochemical study of the relationship between Ki-67 labeling index of proliferating cells of gynecomastia, histological phase and duration of disease
    Seishi Kono
    Department of Pathology, Saitama Cancer Center, Ina machi, Saitama, Japan
    Pathol Int 56:655-8. 2006
    ..041): the shorter the duration the higher the Ki-67 LI. Thus, Ki-67 LI seems a useful tool to examine proliferation activity of gynecomastia and can assist in determination of appropriate treatment of gynecomastia with hormonal therapy...
  19. ncbi request reprint Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03)
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, Kita adachi, Saitama, Japan
    Breast Cancer Res Treat 107:87-94. 2008
    ..Further studies are required to determine the optimal duration of neoadjuvant treatment and to identify response criteria that can more accurately predict long-term outcomes...
  20. ncbi request reprint Nipple adenoma found in a mastectomy specimen: report of a case with special regard to the proliferation pattern
    Seishi Kono
    Department of Pathology, Saitama Cancer Center, Japan
    Breast Cancer 14:234-8. 2007
    ....
  21. ncbi request reprint [Clinicopathological characteristics of familial breast cancer]
    Mari Kamimura
    Division of Breast Surgery, Saitama Cancer Center
    Nihon Rinsho 65:607-9. 2007
  22. ncbi request reprint [Tolerability and safety of docetaxel plus cyclophosphamide as adjuvant chemotherapy for axillary lymph node-negative breast cancer--JECBC04 trial]
    Naohito Yamamoto
    Chiba Cancer Center, Division of Breast Surgery, Chiba, Japan
    Gan To Kagaku Ryoho 37:57-63. 2010
    ..The grade 3/4 toxicity including leukopenia, neutropenia, and febrile neutropenia was manageable. From these results, we consider that TC might become a standard non-anthracycline adjuvant regimen for operable breast cancer...
  23. ncbi request reprint Human leukocyte antigen as a predictive factor of developing bilateral breast cancer in Japanese women
    Takao Yokoe
    Department of Surgery, Shibukawa General Hospital, Gunma University Graduate School of Medicine, Gunma, Japan
    Breast J 12:S201-3. 2006
    ..The risk of bilateral breast cancer in patients with haplotype A24 and Cw7 is 12 times higher compared with those without the haplotype. HLA typing is useful for selecting patients who are at high risk of contralateral breast cancer...
  24. doi request reprint Estrogen signaling ability in human endometrial cancer through the cancer-stromal interaction
    Mitsuyo Matsumoto
    Department of Medical Technology, Tohoku University School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai 981 0872, Japan
    Endocr Relat Cancer 15:451-63. 2008
    ..These results suggest that AI may have some therapeutic value in EC; however, the hormonal microenvironment must be assessed prior to initiating therapy...
  25. ncbi request reprint Breast-conserving surgery following radiation therapy of 50 Gy in stages I and II carcinoma of the breast: the experience at one institute in Japan
    Jun Horiguchi
    Second Department of Surgery, Gunma University Faculty of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    Oncol Rep 9:1053-7. 2002
    ..Local recurrence however, has no adverse effect on survival of patients...
  26. ncbi request reprint The prevalence of intrinsic subtypes and prognosis in breast cancer patients of different races
    Junichi Kurebayashi
    Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    Breast 16:S72-7. 2007
    ..The prevalence of intrinsic subtypes should be taken into account when analyzing survival data in a multi-racial/international clinical study...
  27. ncbi request reprint [Multicenter phase II trial of thrice-weekly docetaxel and weekly trastuzumab as preoperative chemotherapy in patients with HER 2-overexpressing breast cancer--Japan East Cancer Center Breast Cancer Consortium (JECBC) 02 Trial]
    Muneaki Sano
    Dept of Surgery, Niigata Cancer Center Hospital
    Gan To Kagaku Ryoho 33:1411-5. 2006
    ..This regimen promises to be one of the leading future treatments for progressive breast cancer...
  28. ncbi request reprint Breast-conserving therapy versus modified radical mastectomy in the treatment of early breast cancer in Japan
    Jun Horiguchi
    Second Department of Surgery, Gunma University Faculty of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    Breast Cancer 9:160-5. 2002
    ..Breast-conserving therapy has been widely utilized as a treatment option for women with early breast cancer. However, no randomized study comparing modified radical mastectomy and breast-conserving therapy has been conducted in Japan...
  29. ncbi request reprint DPD activity and immunohistochemical DPD expression in human breast cancer
    Jun Horiguchi
    Second Department of Surgery, Gunma University Faculty of Medicine, Gunma 371 8511, Japan
    Oncol Rep 11:65-72. 2004
    ..In conclusion, DPD expression may function as a marker of DPD activity and may be a prognostic indicator for patients with breast cancer...
  30. ncbi request reprint In vitro regulation of vascular endothelial growth factor by estrogens and antiestrogens in estrogen-receptor positive breast cancer
    Hiroyuki Takei
    Northwestern University Medical School, Robert H Lurie Comprehensive Cancer Center, USA
    Breast Cancer 9:39-42. 2002
    ..In this study we investigated the in vitro effects of antiestrogens at different concentrations on vascular endothelial growth factor (VEGF) production in estrogen receptor (ER)-positive breast cancer cells...
  31. ncbi request reprint A mechanism of drug resistance to tamoxifen in breast cancer
    Jennifer MacGregor Schafer
    Robert H Lurie Comprehensive Cancer Center, The Feinberg School of Medicine, Northwestern University, Olson Pavilion 8258, 303 East Chicago Avenue, Chicago, IL 60611, USA
    J Steroid Biochem Mol Biol 83:75-83. 2002
    ..Three phases of tumor progression are described that involve increases in HER-2/neu expression, de-regulation of estrogen receptor expression and increases in apoptosis which in concert determine the phenotype of drug resistance to Tam...
  32. ncbi request reprint The regulatory effect of tamoxifen on fibronectin expression in estrogen-dependent MCF-7 breast carcinoma cells
    Yoshio Horii
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
    Oncol Rep 15:1191-5. 2006
    ..These results suggest that TAM increases FN expression of MCF-7 breast carcinoma cells and that these regulatory effects of TAM on FN expression are partly mediated by TAM-induced TGF-beta...
  33. ncbi request reprint Perfusion CT of breast carcinoma: arterial perfusion of nonscirrhous carcinoma was higher than that of scirrhous carcinoma
    Hiromi Hirasawa
    Department of Diagnostic and Interventional Radiology, Gunma Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Acad Radiol 14:547-52. 2007
    ..Our goals were to apply perfusion CT technique to breast tumor and to evaluate the correlation between arterial perfusion value and other tumor characteristics...
  34. ncbi request reprint Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors
    Satoshi Hirasawa
    Department of Diagnostic and Interventional Radiology, Gunma Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Acad Radiol 14:312-8. 2007
    ..We sought to determine the relationship between tumor blood flow and glucose uptake in head and neck tumors using perfusion computed tomography (PCT) and fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET)...