Yuichi Nakamura

Summary

Affiliation: Saitama Medical School
Country: Japan

Publications

  1. pmc A novel five-way translocation t(7;11;9;22;9)(q22;q13;q34;q11.2;q34) involving Ph chromosome in a patient of chronic myeloid leukemia: a case report
    Sho Yokota
    Department of Hematology, Saitama Medical University Hospital, 38 Moro Hongo, Moroyama machi, Iruma gun, Saitama, 350 0495, Japan
    Mol Cytogenet 5:20. 2012
  2. ncbi request reprint Plasma cell granuloma of the sigmoid colon associated with diverticular disease and accompanying IgM-type monoclonal gammopathy
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, Saitama
    Intern Med 49:227-30. 2010
  3. pmc A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, Saitama, Japan
    Eur J Haematol 82:398-403. 2009
  4. doi request reprint The GAS5 (growth arrest-specific transcript 5) gene fuses to BCL6 as a result of t(1;3)(q25;q27) in a patient with B-cell lymphoma
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, 38 Morohongo, Moroyama machi, Iruma gun, Saitama 350 0495, Japan
    Cancer Genet Cytogenet 182:144-9. 2008
  5. ncbi request reprint Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells
    Kazuo Waga
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Oncogene 22:59-68. 2003
  6. ncbi request reprint TEL/AML1 shows dominant-negative effects over TEL as well as AML1
    Hisako Gunji
    Department of Hematology, Dokkyo University School of Medicine, Tochigi 321 0293, Japan
    Biochem Biophys Res Commun 322:623-30. 2004
  7. ncbi request reprint Cloning and characterization of the novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12)(p13q13)
    Fumihiko Nakamura
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Cancer Res 65:6612-21. 2005
  8. ncbi request reprint [Aplastic anemia complicated with ulcerative colitis]
    Tsuneyuki Shimada
    Department of Hematology, Saitama Medical University Hospital
    Rinsho Ketsueki 53:224-8. 2012
  9. ncbi request reprint [Case with hairy cell leukemia-Japanese variant following radiotherapy for orbital adnexal MALT lymphoma]
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University Hospital
    Rinsho Ketsueki 51:1674-9. 2010
  10. ncbi request reprint Functional regulation of TEL by p38-induced phosphorylation
    Honoka Arai
    Department of Hematology, Dokkyo University School of Medicine, 321 0293, Tochigi, Japan
    Biochem Biophys Res Commun 299:116-25. 2002

Collaborators

Detail Information

Publications18

  1. pmc A novel five-way translocation t(7;11;9;22;9)(q22;q13;q34;q11.2;q34) involving Ph chromosome in a patient of chronic myeloid leukemia: a case report
    Sho Yokota
    Department of Hematology, Saitama Medical University Hospital, 38 Moro Hongo, Moroyama machi, Iruma gun, Saitama, 350 0495, Japan
    Mol Cytogenet 5:20. 2012
    ..Good response with imatinib therapy suggested that a single-event rearrangement was involved in the chromosomal changes...
  2. ncbi request reprint Plasma cell granuloma of the sigmoid colon associated with diverticular disease and accompanying IgM-type monoclonal gammopathy
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, Saitama
    Intern Med 49:227-30. 2010
    ..Recurrent inflammatory process with diverticular disease was considered as a pathogenesis of the pseudoneoplasm and a possible cause of monoclonal proliferation of IgM-producing lymphoid cells in this case...
  3. pmc A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, Saitama, Japan
    Eur J Haematol 82:398-403. 2009
    ..Our study provides further evidence that FL clones, originating from common progenitor cells, can be developed independently at different sites and with different IgL expression after immune selection...
  4. doi request reprint The GAS5 (growth arrest-specific transcript 5) gene fuses to BCL6 as a result of t(1;3)(q25;q27) in a patient with B-cell lymphoma
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University, 38 Morohongo, Moroyama machi, Iruma gun, Saitama 350 0495, Japan
    Cancer Genet Cytogenet 182:144-9. 2008
    ..The GAS5 gene on chromosome 1q25 is the second BCL6 partner, to the SNHG5 on 6q15, which is classified as a non-protein-coding multiple snoRNA host and 5'-TOP class gene...
  5. ncbi request reprint Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells
    Kazuo Waga
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Oncogene 22:59-68. 2003
    ..Endogenous TEL mRNA was found to increase during the first 3 days in differentiating MEL cells and drastically decrease thereafter. All these data suggest that TEL might play some role in erythroid cell differentiation...
  6. ncbi request reprint TEL/AML1 shows dominant-negative effects over TEL as well as AML1
    Hisako Gunji
    Department of Hematology, Dokkyo University School of Medicine, Tochigi 321 0293, Japan
    Biochem Biophys Res Commun 322:623-30. 2004
    ..All these data indicate that TEL/AML1 exerts dominant-interfering effects on both AML1 and TEL, and that expression of TEL/AML1 could result in inactivation of TEL's tumor suppressive functions in t(12;21)-carrying leukemia...
  7. ncbi request reprint Cloning and characterization of the novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12)(p13q13)
    Fumihiko Nakamura
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Cancer Res 65:6612-21. 2005
    ..Loss of tumor suppressive function of wild-type TEL and maintenance of STAT3-mediated signal could at least partly contribute to the leukemogenesis caused by inv(12)(p13q13)...
  8. ncbi request reprint [Aplastic anemia complicated with ulcerative colitis]
    Tsuneyuki Shimada
    Department of Hematology, Saitama Medical University Hospital
    Rinsho Ketsueki 53:224-8. 2012
    ....
  9. ncbi request reprint [Case with hairy cell leukemia-Japanese variant following radiotherapy for orbital adnexal MALT lymphoma]
    Yuichi Nakamura
    Department of Hematology, Saitama Medical University Hospital
    Rinsho Ketsueki 51:1674-9. 2010
    ..This appears to be the first reported case of HCL-Jv associated with other lymphoid tumor. Further analysis is needed to clarify the risk of secondary malignancy in HCL-Jv...
  10. ncbi request reprint Functional regulation of TEL by p38-induced phosphorylation
    Honoka Arai
    Department of Hematology, Dokkyo University School of Medicine, 321 0293, Tochigi, Japan
    Biochem Biophys Res Commun 299:116-25. 2002
    ..These data indicate that TEL's functions are potentially regulated by p38 which is activated by various kinds of stresses. TEL could be a constituent downstream of the specific MAP kinase in the signal transduction system...
  11. pmc A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies
    Hidekazu Kayano
    Department of Pathology, Faculty of Medicine, Saitama Medical University, 38 Moro Hongoh, Moroyama, Iruma gun, Saitama 350 0495, Japan
    Bone Marrow Res 2011:814372. 2011
    ..The observed clonal expansion with plasmacytic differentiation may have occurred under the influence of HCV with HP infection...
  12. ncbi request reprint Monocytic leukemia with CALM/AF10 rearrangement showing mediastinal emphysema
    Fumihiko Nakamura
    Department of Hematology, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu machi, Shimotsuga gun, Tochigi 321 0293, Japan
    Am J Hematol 72:138-42. 2003
    ..Monocytic leukemias with CALM/AF10 fusion are frequently associated with mediastinal invasion. We need to pay special attention to such a complication, even if the chest X-ray is normal at presentation...
  13. ncbi request reprint Serum levels of Thl/Th2 cytokines, angiogenic growth factors, and other prognostic factors in young adult patients with hemophagocytic syndrome
    Ikuo Murohashi
    Department of Medical Technology, Saitama Prefectural University, Saitama, Japan
    Lab Hematol 12:71-4. 2006
    ..Taken together, our findings suggest that both IL-18 and IL-10, but not IL-12, may play important roles in young adult patients with HPS via enhancing and suppressing Th1 immune responses, respectively...
  14. ncbi request reprint Expression of the TEL/EVI1 fusion transcript in a patient with chronic myelogenous leukemia with t(3;12)(q26;p13)
    Yuichi Nakamura
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Am J Hematol 69:80-2. 2002
    ....
  15. ncbi request reprint N-ras and p53 gene mutations in Japanese patients with myeloproliferative disorders
    Shigeharu Tsurumi
    Department of Hematology, Dokkyo University School of Medicine, Tochigi, Japan
    Am J Hematol 71:131-3. 2002
    ..These data suggested that disruptions of both genes are extremely rare in MPD in chronic phase and that loss of functions in the p53 gene could be involved in progression of MPD such as PV and ET...
  16. ncbi request reprint SREBP-2 and NF-Y are involved in the transcriptional regulation of squalene epoxidase
    Masaaki Nagai
    Department of Biochemistry and Internal Medicine, Niigata University School of Medicine, 1 757 Asahimachidori, Niigata 951 8510, Japan
    Biochem Biophys Res Commun 295:74-80. 2002
    ..Another deletion analysis showed that the sequence -207 to -192 bp was also active and it contained nuclear factor Y (NF-Y) binding site. Both sites might play critical roles in sterol mediated regulation of SE gene...
  17. ncbi request reprint Diffuse nodular lymphoid hyperplasia of the large bowel without hypogammaglobulinemia or malabsorption syndrome: a case report and literature review
    Shigeki Tomita
    Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    Int J Surg Pathol 10:297-302. 2002
    ..The present case appears to be an essentially benign condition bearing a resemblance, both clinically and histologically, to malignant lymphoma, and from which it can be distinguished by use of immunohistochemical or molecular analysis...
  18. ncbi request reprint Extranodal diffuse follicular center lymphoma mimicking mantle cell lymphoma of the intestine
    Shigeki Tomita
    Department of Surgical and Molecular Pathology, Dokkyo University School of Medicine, Mibu, Shimo Tsuga, Tochigi, Japan
    Am J Hematol 74:287-9. 2003
    ..Moreover, a cytogenetic study showed a translocation at (14;18)(q32;q21). Finally, this case was diagnosed as diffuse FCL, although the tumor was mimicking mantle cell lymphoma...