T Hirose

Summary

Affiliation: Saitama Medical School
Country: Japan

Publications

  1. ncbi Ectopic thyroid in an adrenal mass: a case report
    Jun Hagiuda
    Department of Urology, Saitama Medical University, Saitama, Japan
    BMC Urol 6:18. 2006
  2. ncbi Ossifying fibromyxoid tumor: invariable ultrastructural features and diverse immunophenotypic expression
    Takanori Hirose
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Ultrastruct Pathol 31:233-9. 2007
  3. ncbi Pleomorphic xanthoastrocytoma: a comparative pathological study between conventional and anaplastic types
    T Hirose
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Histopathology 52:183-93. 2008
  4. ncbi Gliosarcoma: an immunohistochemical, ultrastructural and fluorescence in situ hybridization study
    H Horiguchi
    Department of Pathology, University of Tokushima School of Medicine, Japan
    Pathol Int 48:595-602. 1998
  5. ncbi Olig2 and CD99 are useful negative markers for the diagnosis of brain tumors
    K Ishizawa
    Department of Pathology, Saitama Medical University, Saitama, Japan
    Clin Neuropathol 27:118-28. 2008
  6. ncbi Loss of chromosome 10 in glioblastoma: relation to proliferation and angiogenesis
    H Horiguchi
    Department of Pathology, University of Tokushima, School of Medicine, Japan
    Pathol Int 49:681-6. 1999
  7. ncbi Podoplanin is a potential marker for the diagnosis of ependymoma: a comparative study with epithelial membrane antigen (EMA)
    K Ishizawa
    Department of Pathology, Saitama Medical University, Saitama, Japan
    Clin Neuropathol 28:373-8. 2009
  8. ncbi Current and future perspectives on the TARGET system: the registration system for Glivec established by the JSH
    Masahiro Kizaki
    Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan
    Int J Hematol 88:409-17. 2008
  9. ncbi Pharmacokinetics of 5-fluorouracil in elderly Japanese patients with cancer treated with S-1 (a combination of tegafur and dihydropyrimidine dehydrogenase inhibitor 5-chloro-2,4-dihydroxypyridine)
    K Fujita
    Department of Medical Oncology, Saitama International Medical Center Comprehensive Cancer Center, Saitama Medical University, 1397 1 Yamane, Hidaka, Saitama 350 1298, Japan
    Drug Metab Dispos 37:1375-7. 2009
  10. ncbi Adult neuroblastoma of the retroperitoneum and abdomen: clinicopathologic distinction from primitive neuroectodermal tumor
    T Hasegawa
    Department of Pathology, National Cancer Center Research Institute and Hospital, Tokyo, Japan
    Am J Surg Pathol 25:918-24. 2001

Detail Information

Publications40

  1. ncbi Ectopic thyroid in an adrenal mass: a case report
    Jun Hagiuda
    Department of Urology, Saitama Medical University, Saitama, Japan
    BMC Urol 6:18. 2006
    ..A few cases of ectopic lesions have been reported in the literature for abdominal organs including the adrenal glands, but the mechanism by which the thyroid components migrate into the abdomen has been poorly understood...
  2. ncbi Ossifying fibromyxoid tumor: invariable ultrastructural features and diverse immunophenotypic expression
    Takanori Hirose
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Ultrastruct Pathol 31:233-9. 2007
    ..The salient and invariable ultrastructural features included reduplicated basal laminas, which seem to be crucial for the diagnosis...
  3. ncbi Pleomorphic xanthoastrocytoma: a comparative pathological study between conventional and anaplastic types
    T Hirose
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Histopathology 52:183-93. 2008
    ..To facilitate the understanding and correct diagnosis of the anaplastic variant of pleomorphic xanthoastrocytoma (PXA)...
  4. ncbi Gliosarcoma: an immunohistochemical, ultrastructural and fluorescence in situ hybridization study
    H Horiguchi
    Department of Pathology, University of Tokushima School of Medicine, Japan
    Pathol Int 48:595-602. 1998
    ..As similar aberrations have been reported in GBM, these chromosomal abnormalities suggest a common pathogenesis in GS and GBM...
  5. ncbi Olig2 and CD99 are useful negative markers for the diagnosis of brain tumors
    K Ishizawa
    Department of Pathology, Saitama Medical University, Saitama, Japan
    Clin Neuropathol 27:118-28. 2008
    ..The CD99-immunohistochemistry is unique in that it is helpful for the diagnosis of clear cell brain tumors through the visualization of CD99-negative clear cells...
  6. ncbi Loss of chromosome 10 in glioblastoma: relation to proliferation and angiogenesis
    H Horiguchi
    Department of Pathology, University of Tokushima, School of Medicine, Japan
    Pathol Int 49:681-6. 1999
    ..However, neither the loss of chromosome 10 nor number of vessels was not correlated with VEGF expression. Other genetic abnormalities as well as loss of chromosome 10 may be involved in the cell proliferation and angiogenesis of GBM...
  7. ncbi Podoplanin is a potential marker for the diagnosis of ependymoma: a comparative study with epithelial membrane antigen (EMA)
    K Ishizawa
    Department of Pathology, Saitama Medical University, Saitama, Japan
    Clin Neuropathol 28:373-8. 2009
    ..Anti-podoplanin antibodies and anti-EMA antibodies could cooperate with each other for the diagnostic immunohistochemistry of ependymoma...
  8. ncbi Current and future perspectives on the TARGET system: the registration system for Glivec established by the JSH
    Masahiro Kizaki
    Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan
    Int J Hematol 88:409-17. 2008
    ..Based on these cumulative data, present imatinib treatment trends were analyzed and safety and efficacy were compared with international trial data...
  9. ncbi Pharmacokinetics of 5-fluorouracil in elderly Japanese patients with cancer treated with S-1 (a combination of tegafur and dihydropyrimidine dehydrogenase inhibitor 5-chloro-2,4-dihydroxypyridine)
    K Fujita
    Department of Medical Oncology, Saitama International Medical Center Comprehensive Cancer Center, Saitama Medical University, 1397 1 Yamane, Hidaka, Saitama 350 1298, Japan
    Drug Metab Dispos 37:1375-7. 2009
    ..The opposing effects of aging on the oral clearance of tegafur and the AUC of CDHP may offset each other, leading to unchanged systemic exposure of 5-FU...
  10. ncbi Adult neuroblastoma of the retroperitoneum and abdomen: clinicopathologic distinction from primitive neuroectodermal tumor
    T Hasegawa
    Department of Pathology, National Cancer Center Research Institute and Hospital, Tokyo, Japan
    Am J Surg Pathol 25:918-24. 2001
    ..Appropriate immunohistochemical studies and laboratory examination enable pathologists to distinguish ANB from other differential diagnoses, especially PNET...
  11. ncbi Tumor imprint cytology of ovarian ependymoma. A case report
    Y Komuro
    Department of Obstetrics and Gynecology, National Saitama Hospital, Wako City, Saitama, Japan
    Cancer 92:3165-9. 2001
    ..To our knowledge, this is the first report on the imprint cytologic diagnosis of ependymoma originating in the ovary...
  12. ncbi Adenosarcoma of the uterine cervix presenting as a cervical polyp
    A Hino
    Department of Pathology, University of Tokushima School of Medicine, Japan
    Pathol Int 48:649-52. 1998
    ..When they arise from the cervix, adenosarcomas may be confused with benign cervical polyps clinically and pathologically. As the former often recurs, microscopic differentiation is crucial for further treatment...
  13. ncbi A neuroepithelial tumor showing combined histological features of dysembryoplastic neuroepithelial tumor and pleomorphic xanthoastrocytoma--a case report and review of the literature
    K Ishizawa
    Department of Pathology, Saitama Medical University, Saitama, Japan
    Clin Neuropathol 26:169-75. 2007
    ..A reticulin network was developed among the tumor cells (PXA-like component, WHO Grade III). This case illustrates an unusual composite brain tumor, combined DNT and PXA...
  14. ncbi Ultrastructural features of pleomorphic xanthoastrocytoma: a comparative study with glioblastoma multiforme
    T Hirose
    Department of Pathology, Saitama Medical School, Japan
    Ultrastruct Pathol 25:469-78. 2001
    ..The authors conclude that PXA is fundamentally an astrocytic tumor, albeit one with a significant tendency to undergo neuronal differentiation...
  15. ncbi TP53 deleted cells in de novo glioblastomas using fluorescence in situ hybridization
    H Horiguchi
    Department of Pathology, University of Tokushima School of Medicine, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Pathol Int 51:187-92. 2001
    ....
  16. ncbi Hemodynamic infarction of the spinal cord: involvement of the gray matter plus the border-zone between the central and peripheral arteries
    K Ishizawa
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Spinal Cord 43:306-10. 2005
    ..The former is probably associated with selective vulnerability of the gray matter to ischemia, while the latter is probably associated with intrinsic vulnerability of the border-zone to systemic hypotension or low blood-flow states...
  17. ncbi Differences in IgE isotype switching induced by anti-CD40 monoclonal antibody and cytokines among subtypes of chronic B lymphoid leukemias
    H Takeuchi
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Exp Hematol 28:543-50. 2000
    ..Immunologic differences among the chronic B lymphoid leukemias defined by the French-American-British (FAB) classification were evaluated with respect to IgE isotype switching induced by anti-CD40 monoclonal antibody (mAb) and cytokines...
  18. ncbi Lipomatous primitive neuroectodermal tumor with a glioblastoma component: a case report
    K Ishizawa
    Department of Pathology, Saitama Medical School, Morohongo 38, Moroyama, Irumagun, Saitama 350 0495, Japan
    Acta Neuropathol 103:193-8. 2002
    ..The association with a GBM component makes the present tumor a unique, and, to our knowledge, previously unrecognized lesion...
  19. ncbi The innervation of intradermal nevi. On the nevus-axon relations
    P Yang
    Department of Pathology, University of Tokushima School of Medicine, Japan
    Zentralbl Pathol 139:295-9. 1993
    ..The mode of contact between nevus cell and axon, the presence of true Schwann cells surrounding the proliferated axons and the demonstration of myelin structure should be investigated by further electron microscopic study...
  20. ncbi Calcifying fibrous pseudotumor: an ultrastructural study
    T Maeda
    Department of Pathology, Ehime Prefectural Central Hospital, Matsuyama, Japan
    Ultrastruct Pathol 23:189-92. 1999
    ..Extracellular calcified substances often abutted to fibroblasts. Fibroblasts may play an important role in both intracellular and extracellular calcifications of CFT...
  21. ncbi Angiosarcoma of the breast: report of a case and its findings of MRI
    S Murakam
    Second Department of Surgery, Saitama Medical School, 38 Morohongo, Moroyama-machi, Iruma-gunn, Saitama 350-0495, Japan
    Breast Cancer 8:254-8. 2001
    ..She underwent modified radical mastectomy and is now free of recurrence. This case emphasizes the difficulties in the clinical diagnosis of angiosarcoma of the breast...
  22. ncbi Malignant mixed müllerian tumor of primary mesenteric origin
    M Mikami
    Department of Obstetrics and Gynecology, National Saitama Hospital, Wako, Saitama, Japan
    Int J Gynecol Cancer 15:1249-53. 2005
    ..5%). Peritoneal MMMT are frequently associated with gynecologic tumors...
  23. ncbi Low grade malignant peripheral nerve sheath tumour: varied cytological and histological patterns
    U Yamaguchi
    Division of Orthopaedic Oncology, National Cancer Centre, Hospital and Research Institute, Tokyo 104-0045, Japan
    J Clin Pathol 56:826-30. 2003
    ..CONCLUSIONS: These findings suggest that careful clinical and histological evaluation, along with S-100 protein immunostaining, are essential for the accurate diagnosis of low grade MPNST...
  24. ncbi Marked asymmetry of putaminal pathology in an MSA-P patient with Pisa syndrome
    I Hozumi
    Department of Neurology and Geriatrics, Gifu University, School of Medicine, Gifu, Japan
    Mov Disord 19:470-2. 2004
    ..The pathophysiological mechanism underlying forms of axial dystonia remains to be elucidated. We report here the histopathological findings of a multiple system atrophy of parkinsonian predominance (MSA-P) patient with Pisa syndrome...
  25. ncbi Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway
    B Hu
    University of Pittsburgh Cancer Institute and Department of Pathology, Pittsburgh, PA 15213 1863, USA
    Oncogene 26:5577-86. 2007
    ....
  26. ncbi Temporary hyperglycaemia provokes monocyte adhesion to endothelial cells in rat thoracic aorta
    A Otsuka
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
    Diabetologia 48:2667-74. 2005
    ..CONCLUSIONS/INTERPRETATION: Our data demonstrate that a temporary rise in blood glucose levels can in itself promote a reversible increase in monocyte adhesion to arterial endothelial cells...
  27. ncbi Expression of smooth muscle markers in so called malignant fibrous histiocytomas
    T Hasegawa
    Pathology Division, National Cancer Centre Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Clin Pathol 56:666-71. 2003
    ..To obtain further information regarding the frequency and degree of positivity for smooth muscle markers in a large number of malignant fibrous histiocytomas (MFHs), as an aid to accurate diagnosis...
  28. ncbi Structural organisation and chromosomal mapping of the human Id-3 gene
    R W Deed
    CRC Department of Gene Regulation, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK
    Gene 151:309-14. 1994
    ..1 by fluorescence in situ hybridisation (FISH) and, using the same FISH technique, we have detected heterogeneity in tumour-associated 1p36 chromosome translocations...
  29. ncbi Characterization of the response element and DNA binding properties of the nuclear orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor
    Z H Yan
    Department of Medicine III, Osaka University Medical School, Yamadaoka, Suita, Osaka 565, Japan
    J Biol Chem 272:10565-72. 1997
    ..Transfection of RTR in CV-1 cells was unable to cause RTRE-dependent transactivation of a CAT reporter gene; however, an RTR-VP16 fusion protein could induce transactivation through several RTREs, including P2-RE...
  30. ncbi Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiation
    W Lei
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 18:167-76. 1997
    ..Our observations suggest that GCNF/RTR plays a role in the control of gene expression in early embryogenesis and during spermatogenesis...
  31. ncbi PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons
    T Hirose
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Suita, Japan
    Eur J Biochem 249:481-8. 1997
    ..These findings suggest that PCTAIRE 2 is a Ser/Thr kinase that might play a unique role in terminally differentiated neurons...
  32. ncbi Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells
    S Austin
    Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA
    Cell Growth Differ 9:267-76. 1998
    ....
  33. ncbi An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    Y Izumi
    Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
    J Cell Biol 143:95-106. 1998
    ....
  34. ncbi Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
    Y Sugiyama
    Department of Molecular Biology, Yokohama City University School of Medicine, Kanazawa Ku, Yokohama 236 0004, Japan
    J Biol Chem 275:1095-104. 2000
    ..Taken together, the results suggest that muscle cells develop two kinds of stress response systems composed of diverged sHSP members, and that these systems work independently in muscle maintenance and differentiation...
  35. ncbi Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
    A Suzuki
    Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
    J Cell Biol 152:1183-96. 2001
    ..These results indicate that aPKC is involved in the evolutionarily conserved PAR protein complex, and plays critical roles in the development of the junctional structures and apico-basal polarization of mammalian epithelial cells...
  36. ncbi The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
    K Ebnet
    Institute of Cell Biology, ZMBE, University of Muenster, D 48149 Muenster, Germany
    EMBO J 20:3738-48. 2001
    ..Our data suggest that the ASIP/PAR-3-aPKC complex is tethered to tight junctions via its association with JAM, indicating a potential role for JAM in the generation of cell polarity in epithelial cells...
  37. ncbi TNF-alpha inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPbeta and delta
    S Kurebayashi
    Department of Molecular Medicine, Osaka University Medical School, Suita, Japan
    Endocr J 48:249-53. 2001
    ..Our results suggest that TNF-alpha inhibits adipocyte differentiation independently of the downregulation of C/EBPbeta and C/EBPdelta...
  38. ncbi PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
    T Yamanaka
    Department of Molecular Biology, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan
    Genes Cells 6:721-31. 2001
    ....
  39. ncbi Dynamic changes in protein components of the tight junction during liver regeneration
    Y Takaki
    Department of Molecular Biology, Yokohama City University School of Medicine, Kanazawa-ku, Yokohama 236-0004, Japan
    Cell Tissue Res 305:399-409. 2001
    ....
  40. ncbi TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily
    T Hirose
    Cell Biology Section, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Mol Endocrinol 8:1667-80. 1994
    ..In the testis, TAK1 appears to control gene expression during spermatogenesis, particularly during the meiotic phase...