Keiko Morikawa

Summary

Affiliation: Sagami Women's University
Country: Japan

Publications

  1. ncbi Modulatory effect of macrolide antibiotics on the Th1- and Th2-type cytokine production
    K Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Bunkyo 2 1 1, Kanagawa 228 8533, Sagamihara, Japan
    Int J Antimicrob Agents 19:53-9. 2002
  2. ncbi Inhibitory effect of quercetin on carrageenan-induced inflammation in rats
    Keiko Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa, 228 8533 Japan
    Life Sci 74:709-21. 2003
  3. ncbi All-trans-retinoic acid accelerates the differentiation of human B lymphocytes maturing into plasma cells
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Sagamihara, Kanagawa 228 8533, Japan
    Int Immunopharmacol 5:1830-8. 2005
  4. ncbi Modulatory effect of fosfomycin on acute inflammation in the rat air pouch model
    K Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Int J Antimicrob Agents 21:334-9. 2003
  5. ncbi Epigallocatechin gallate-induced apoptosis does not affect adipocyte conversion of preadipocytes
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Cell Biol Int 31:1379-87. 2007
  6. ncbi Growth arrest and apoptosis induced by quercetin is not linked to adipogenic conversion of human preadipocytes
    Keiko Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, Sagamihara, Kanagawa, Japan
    Metabolism 56:1656-65. 2007
  7. ncbi Characterization of granulocyte colony-stimulating factor receptor expressed on human lymphocytes
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Sagamihara, Kanagawa, Japan
    Br J Haematol 118:296-304. 2002
  8. ncbi Modulation of IgD and CD20 by ligation of CD5 on tonsillar B cells
    K Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Faculty of Liberal Arts, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Scand J Immunol 55:44-52. 2002
  9. ncbi Synergistic effect of fosfomycin and arbekacin on a methicillin-resistant Staphylococcus aureus-induced biofilm in a rat model
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Int J Antimicrob Agents 25:44-50. 2005
  10. ncbi Effect of arbekacin on a methicillin-resistant Staphylococcus aureus-induced biofilm in a rat model
    Yuka Yoshikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa, 228 8533, Japan
    J Infect Chemother 10:268-73. 2004

Collaborators

Detail Information

Publications28

  1. ncbi Modulatory effect of macrolide antibiotics on the Th1- and Th2-type cytokine production
    K Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Bunkyo 2 1 1, Kanagawa 228 8533, Sagamihara, Japan
    Int J Antimicrob Agents 19:53-9. 2002
    ..Clarithromycin had the most potent inhibitory effect of the drugs used. The present results suggested that anti-bacterial agents might modify the host's immunological response by interfering with the activity of T helper cells...
  2. ncbi Inhibitory effect of quercetin on carrageenan-induced inflammation in rats
    Keiko Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa, 228 8533 Japan
    Life Sci 74:709-21. 2003
    ..Our study indicated that the flavonols modulated the inflammatory response, at least in part, by modulating the prostanoid synthesis as well as cytokine production...
  3. ncbi All-trans-retinoic acid accelerates the differentiation of human B lymphocytes maturing into plasma cells
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Sagamihara, Kanagawa 228 8533, Japan
    Int Immunopharmacol 5:1830-8. 2005
    ..Taken together, this study showed that retinoic acid could accelerate the differentiation of B cells maturing into antibody producing cells...
  4. ncbi Modulatory effect of fosfomycin on acute inflammation in the rat air pouch model
    K Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Int J Antimicrob Agents 21:334-9. 2003
    ..The contents of PGE(2) and TNF-alpha, and mRNA for cyclooxygenase-2 were also markedly suppressed in FOM-treated rats. Histological examination showed suppression of the inflammatory response in the pouch tissues from FOM-treated rats...
  5. ncbi Epigallocatechin gallate-induced apoptosis does not affect adipocyte conversion of preadipocytes
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Cell Biol Int 31:1379-87. 2007
    ..Our results suggest that EGCG induces growth arrest and apoptosis, but does not affect adipocyte conversion of preadipocytes...
  6. ncbi Growth arrest and apoptosis induced by quercetin is not linked to adipogenic conversion of human preadipocytes
    Keiko Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, Sagamihara, Kanagawa, Japan
    Metabolism 56:1656-65. 2007
    ..These results suggested that apoptosis induced by quercetin was not linked to adipogenic conversion of preadipocytes...
  7. ncbi Characterization of granulocyte colony-stimulating factor receptor expressed on human lymphocytes
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, Sagamihara, Kanagawa, Japan
    Br J Haematol 118:296-304. 2002
    ..Our results indicated that G-CSFR was constitutively expressed on the B-cell surface and was inducible in T cells...
  8. ncbi Modulation of IgD and CD20 by ligation of CD5 on tonsillar B cells
    K Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Faculty of Liberal Arts, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Scand J Immunol 55:44-52. 2002
    ..Our findings suggest that ligation of CD5 might transduce the signal to regulate B cell maturation...
  9. ncbi Synergistic effect of fosfomycin and arbekacin on a methicillin-resistant Staphylococcus aureus-induced biofilm in a rat model
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Int J Antimicrob Agents 25:44-50. 2005
    ..These results suggested an enhancement of bactericidal activity of arbekacin penetrating through the biofilm layer by virtue of fosfomycin. A possible mechanism of the synergistic effect is discussed...
  10. ncbi Effect of arbekacin on a methicillin-resistant Staphylococcus aureus-induced biofilm in a rat model
    Yuka Yoshikawa
    Division of Clinical Nutrition, Department of Nutrition, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa, 228 8533, Japan
    J Infect Chemother 10:268-73. 2004
    ....
  11. doi Effect of genistein and daidzein on the proliferation and differentiation of human preadipocyte cell line
    Kaori Hirota
    Division of Clinical Nutrition, Department of Nutritional Science, Sagami Women s University, Sagamihara, Kanagawa, Japan
    J Agric Food Chem 58:5821-7. 2010
    ..These results suggested that only aglycon forms of isoflavones induced not only apoptosis but also lipogenesis in the preadipocyte cell line AML-I. The possible mechanism of these phenomena has been discussed in the text...
  12. doi All-trans retinoic acid displays multiple effects on the growth, lipogenesis and adipokine gene expression of AML-I preadipocyte cell line
    Keiko Morikawa
    Division of Clinical Nutrition, Department of Nutritional Science, Sagami Women s University, 2 1 1 Bunkyo, Sagamihara, Kanagawa 228 8533, Japan
    Cell Biol Int 37:36-46. 2013
    ..The data suggest that ATRA exerts a wide range of effects--growth arrest, apoptosis, lipogenesis and modulation of adipokine gene expression--during the maturation of preadipocytes into adipocytes...
  13. doi Induction of apoptosis and lipogenesis in human preadipocyte cell line by n-3 PUFAs
    Haruka Hanada
    Division of Clinical Nutrition, Department of Nutritional Science, Sagami Womens University, 211 Bunkyo, Sagamihara, Kanagawa 2288533, Japan
    Cell Biol Int 35:51-9. 2011
    ..These results suggest that EPA and DHA promote differentiation, inhibit proliferation and induce apoptosis in preadipocyte cell line AML-I...
  14. doi Naringenin and hesperetin induce growth arrest, apoptosis, and cytoplasmic fat deposit in human preadipocytes
    Keiko Morikawa
    Department of Nutrition, Division of Clinical Nutrition, Sagami Women s University, Sagamihara, Kanagawa, Japan
    J Agric Food Chem 56:11030-7. 2008
    ..These data suggest that apoptosis by flavanones does not inhibit the adipocytic conversion of AML-I preadipocytes. The result also indicates that adipocyte may not be a direct target for the lipid-lowering activity of the flavanones...
  15. ncbi Time- and dose-dependent effect of fosfomycin on suppression of infection-induced endotoxin shock in mice
    Kiichiro Kawaguchi
    Medicinal Plant Garden, School of Pharmaceutical Sciences, Kitasato University, Sagamihara, Kanagawa, Japan
    Biol Pharm Bull 25:1658-61. 2002
    ..Plasma levels of LPS released from bacilli were significantly higher in FOF- than IPM-treated mice and infection controls, but both antibiotics showed similar efficacy in protection...
  16. ncbi Establishment of a human preadipose cell line, HPB-AML-I: refractory to PPARgamma-mediated adipogenic stimulation
    Ikuko Torii
    Department of Pathology, 1st Unit, Shimane Medical University, Izumo, Japan
    J Cell Physiol 197:42-52. 2003
    ....
  17. ncbi Endothelial nitric oxide synthase-independent effects of an ACE inhibitor on coronary flow response to bradykinin in aged mice
    M A Hassan Talukder
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    J Cardiovasc Pharmacol 44:557-63. 2004
    ..These results indicate that coronary flow response to bradykinin is preserved in aged mice even in the absence of eNOS, and an ACE inhibitor augments this response by both eNOS-dependent and -independent mechanisms...
  18. ncbi Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats
    Yasushi Mukai
    Department of Cardiovascular Medicine, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan
    Arterioscler Thromb Vasc Biol 22:1445-50. 2002
    ..We examined what treatment could ameliorate the endothelial dysfunction associated with aging in rats...
  19. ncbi Ferulic acid attenuated cognitive deficits and increase in carbonyl proteins induced by buthionine-sulfoximine in mice
    Takayoshi Mamiya
    Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Meijo University, 150 Yagotoyama, Tempaku ku, Nagoya 468 8503, Japan
    Neurosci Lett 430:115-8. 2008
    ..These findings suggest that pretreatment with FA may attenuate the memory deficits and increase the carbonyl protein levels induced by BSO in mice...
  20. ncbi Role of Cu,Zn-SOD in the synthesis of endogenous vasodilator hydrogen peroxide during reactive hyperemia in mouse mesenteric microcirculation in vivo
    Toyotaka Yada
    Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192 Japan
    Am J Physiol Heart Circ Physiol 294:H441-8. 2008
    ..Endothelial Cu,Zn-SOD plays an important role in the synthesis of endogenous H(2)O(2) that contributes to RH in mouse mesenteric smaller arterioles...
  21. ncbi Axonemal localization of Chlamydomonas PACRG, a homologue of the human Parkin-coregulated gene product
    Kazuho Ikeda
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Cell Motil Cytoskeleton 64:814-21. 2007
    ..From these and other results, we propose that PACRG is a structural component of the doublet and triplet microtubules possibly involved in inter-tubule linkage...
  22. ncbi Characterization of Arp2/3 complex in chicken tissues
    Asako G Terasaki
    Graduate School of Science and Technology, Chiba University, Chiba, Japan
    Cell Struct Funct 27:383-91. 2002
    ....
  23. ncbi Effects of pre-germinated brown rice on depression-like behavior in mice
    Takayoshi Mamiya
    Department of Chemical Pharmacology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku ku, Nagoya 468 8503, Japan
    Pharmacol Biochem Behav 86:62-7. 2007
    ..These results suggest that the increase of 5-HT levels in the mouse frontal cortex contributes to the antidepressant-like effects of PGBR pellets...
  24. ncbi Sustained elevation of serum cortisol level causes sensitization of coronary vasoconstricting responses in pigs in vivo: a possible link between stress and coronary vasospasm
    Takatoshi Hizume
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Circ Res 99:767-75. 2006
    ..These results indicate that sustained elevation of serum cortisol level sensitizes coronary vasoconstricting responses through Rho-kinase activation, suggesting the link between stress and coronary vasospasm...
  25. pmc Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization
    Keiko Morikawa
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    J Clin Invest 112:1871-9. 2003
    ..These results prove the novel concept that endothelial Cu,Zn-SOD plays an important role as an "EDHF synthase" in mice, in addition to its classical role to scavenge superoxide anions...
  26. ncbi Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells
    Junko Hiroki
    Department of Cardiovascular Medicine, and the 21st Century COE Program on Lifestyle Related Diseases, Kyushu University Graduate School of Medical Sciences, 3 1 1 Maldashi, Higashi ku, Fukuoka 812 8582, Japan
    J Mol Cell Cardiol 37:537-46. 2004
    ..These results indicate that the expression and function of Rho-kinase are upregulated by inflammatory stimuli (e.g. angiotensin II and IL-1beta) in hcVSMC with an involvement of PKC and NF-kappaB both in vitro and in vivo...
  27. ncbi Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries
    Keiko Morikawa
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    J Cardiovasc Pharmacol 44:552-6. 2004
    ..These results indicate that SOD plays an important role in EDHF-mediated relaxations and hyperpolarizations of human mesenteric arteries...
  28. ncbi Prostacyclin does not inhibit rho-kinase: an implication for the treatment of pulmonary hypertension
    Kohtaro Abe
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    J Cardiovasc Pharmacol 45:120-4. 2005
    ..These results indicate that prostacyclin lacks direct inhibitory effect on Rho-kinase and suggest that combination therapy with prostacyclin and a Rho-kinase inhibitor could exert further beneficial effects on PH...