Mikio Nishizawa

Summary

Affiliation: Ritsumeikan University
Country: Japan

Publications

  1. ncbi request reprint Regulation of inducible gene expression by natural antisense transcripts
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan
    Front Biosci (Landmark Ed) 17:938-58. 2012
  2. doi request reprint Supplementation with a flavanol-rich lychee fruit extract influences the inflammatory status of young athletes
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Phytother Res 25:1486-93. 2011
  3. doi request reprint Natural antisense transcript-targeted regulation of inducible nitric oxide synthase mRNA levels
    Emi Yoshigai
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Nitric Oxide 30:9-16. 2013
  4. pmc The anti-inflammatory effects of flavanol-rich lychee fruit extract in rat hepatocytes
    Ryota Yamanishi
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    PLoS ONE 9:e93818. 2014
  5. pmc Stabilization of human interferon-α1 mRNA by its antisense RNA
    Tominori Kimura
    Laboratory of Microbiology and Cell Biology, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525 8577, Japan
    Cell Mol Life Sci 70:1451-67. 2013
  6. doi request reprint Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1β-treated hepatocytes
    Emi Yoshigai
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan Ritsumeikan Global Innovation Research Organization R GIRO, Kusatsu, Shiga, Japan
    Biochem Biophys Res Commun 439:54-9. 2013
  7. doi request reprint A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes
    Ayaka Nakajima
    a Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Japan
    Biosci Biotechnol Biochem 79:138-46. 2015
  8. ncbi request reprint Post-transcriptional inducible gene regulation by natural antisense RNA
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan
    Front Biosci (Landmark Ed) 20:1-36. 2015
  9. doi request reprint Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages
    Hiroyuki Inaba
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan Research and Development Headquarters, Lion Corporation, Odawara, Kanagawa, Japan
    Nitric Oxide 44:61-70. 2015
  10. doi request reprint Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPβ and NF-κB in rat hepatocytes
    Yuna Takimoto
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Nitric Oxide 28:47-56. 2013

Collaborators

  • Tominori Kimura
  • A Hon Kwon
  • Hoyoku Nishino
  • Takashi Matsuura
  • Emi Yoshigai
  • Tadayoshi Okumura
  • Tetsuya Okuyama
  • Yukinobu Ikeya
  • Ryota Yamanishi
  • Ayaka Nakajima
  • Hiroyuki Inaba
  • Toru Machida
  • Hiromitsu Murase
  • Masatoshi Mori
  • Yuna Takimoto
  • Keikichi Sugiyama
  • Hirotaka Matsuo
  • Mayuri Namba
  • Yuka Yamamoto
  • Nao Yoshinaka
  • Michiaki Murakoshi
  • Yoshiro Araki
  • Takafumi Hara
  • Masaharu Oishi
  • Hai yan Qian
  • Yoshito Tanaka
  • Katsuji Tokuhara
  • Masaki Kaibori

Detail Information

Publications13

  1. ncbi request reprint Regulation of inducible gene expression by natural antisense transcripts
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan
    Front Biosci (Landmark Ed) 17:938-58. 2012
    ....
  2. doi request reprint Supplementation with a flavanol-rich lychee fruit extract influences the inflammatory status of young athletes
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Phytother Res 25:1486-93. 2011
    ..These findings suggest that FRLFE supplementation may suppress inflammation or tissue damage caused by high-intensity exercise training...
  3. doi request reprint Natural antisense transcript-targeted regulation of inducible nitric oxide synthase mRNA levels
    Emi Yoshigai
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Nitric Oxide 30:9-16. 2013
    ..These results suggest that NATRE technology using iNOS sense oligonucleotides could potentially be used to treat human inflammatory diseases and cancers by reducing iNOS mRNA levels...
  4. pmc The anti-inflammatory effects of flavanol-rich lychee fruit extract in rat hepatocytes
    Ryota Yamanishi
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    PLoS ONE 9:e93818. 2014
    ..Our results suggest that flavanols may be responsible for the anti-inflammatory and hepatoprotective effects of FRLFE and may be used to treat inflammatory diseases. ..
  5. pmc Stabilization of human interferon-α1 mRNA by its antisense RNA
    Tominori Kimura
    Laboratory of Microbiology and Cell Biology, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525 8577, Japan
    Cell Mol Life Sci 70:1451-67. 2013
    ....
  6. doi request reprint Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1β-treated hepatocytes
    Emi Yoshigai
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan Ritsumeikan Global Innovation Research Organization R GIRO, Kusatsu, Shiga, Japan
    Biochem Biophys Res Commun 439:54-9. 2013
    ..Nobiletin may suppress the induction of inducible nitric oxide synthase (iNOS), which synthesizes the inflammatory mediator nitric oxide (NO) in hepatocytes...
  7. doi request reprint A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes
    Ayaka Nakajima
    a Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Japan
    Biosci Biotechnol Biochem 79:138-46. 2015
    ..The present findings suggest that these constituents, including shisoflavanone A, may be involved in the anti-inflammatory effects of green perilla leaves. ..
  8. ncbi request reprint Post-transcriptional inducible gene regulation by natural antisense RNA
    Mikio Nishizawa
    Department of Biomedical Sciences, College of Life Sciences, Kusatsu, Shiga, Japan
    Front Biosci (Landmark Ed) 20:1-36. 2015
    ..The post-transcriptional mechanisms via these RNA-RNA interactions may play pivotal roles to regulate inducible gene expression and present the possibility of the involvement of asRNAs in various diseases. ..
  9. doi request reprint Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages
    Hiroyuki Inaba
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan Research and Development Headquarters, Lion Corporation, Odawara, Kanagawa, Japan
    Nitric Oxide 44:61-70. 2015
    ..Therefore, antipyretic analgesic drugs may decrease NO production by modulating the NF-κB pathway in different ways, which could confer different efficacies and potencies with regard to their anti-inflammatory effects. ..
  10. doi request reprint Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPβ and NF-κB in rat hepatocytes
    Yuna Takimoto
    Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan
    Nitric Oxide 28:47-56. 2013
    ....
  11. doi request reprint Japanese herbal medicine, inchinkoto, inhibits inducible nitric oxide synthase induction in interleukin-1β-stimulated hepatocytes
    Takashi Matsuura
    Department of Surgery, Kansai Medical University, Moriguchi, Osaka Graduate School of Science and Engineering Departments of Pharmacy, College of Pharmaceutical Sciences Biomedical Sciences, College of Life Sciences Research Organization of Science and Technology, Ritsumeikan University, Kusatsu, Shiga, Japan
    Hepatol Res 42:76-90. 2012
    ..TJ-135 may have therapeutic potential for various liver injuries through the suppression of iNOS induction...
  12. pmc Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270
    Tominori Kimura
    Department of Pharmacy, Laboratory of Microbiology and Cell Biology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525 8577, Japan
    Cell Mol Life Sci 72:2749-61. 2015
    ..This coordinated regulatory architecture suggests a vital function for the innate immune system in maintaining precise physiological type I IFN levels via post-transcriptional regulatory mechanisms. ..
  13. doi request reprint Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-α 1 mRNA
    Tominori Kimura
    Laboratory of Microbiology and Cell Biology, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525 8577, Japan
    Med Mol Morphol 43:145-57. 2010
    ..We showed that RNPS1 might recognize IFN-α1 mRNP that includes CRM1. The data demonstrate that interaction between RNA structures in the coding region and CRM1 affects the nucleocytoplasmic translocation of IFN-α1 mRNA...