Research Topics
Genomes and GenesSpecies | Daisuke ShimosatoSummaryAffiliation: RIKEN Brain Science Institute Country: Japan Publications
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Detail Information
Publications
Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cellsDaisuke Shimosato
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, Minatojima Minamimachi, Chuo Ku, Kobe, Hyogo, Japan
BMC Dev Biol 7:80. 2007....
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cellsShinji Masui
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Minatojima minamimachi 2 2 3, Chu o ku, Kobe, Hyogo 650 0047, Japan
Nat Cell Biol 9:625-35. 2007..These results indicate that the essential function of Sox2 is to stabilize ES cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression...
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiationHitoshi Niwa
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, 2 2 3 Minatojima minamimachi, Kobe, Hyogo 650 0047, Japan
Cell 123:917-29. 2005..This suggests that reciprocal inhibition between lineage-specific transcription factors might be involved in the first differentiation event of mammalian development...
Identification and characterization of subpopulations in undifferentiated ES cell cultureYayoi Toyooka
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chu o ku, Kobe, Hyogo, Japan
Development 135:909-18. 2008..These results confirmed that undifferentiated ES cell culture contains subpopulations corresponding to ICM, epiblast and PrE...
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cellsKazuya Ogawa
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan
Biochem Biophys Res Commun 343:159-66. 2006..These observations indicate that the Wnt signal mediated by the canonical pathway is not sufficient but enhances the effect of LIF to maintain self-renewal of mouse ES cells...
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cellsHitoshi Niwa
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 6500047, Japan
Nature 460:118-22. 2009....
Activin-Nodal signaling is involved in propagation of mouse embryonic stem cellsKazuya Ogawa
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
J Cell Sci 120:55-65. 2007..These findings suggest that endogenously activated autocrine loops of activin-Nodal signaling promote ES cell self-renewal...
An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unitShinji Masui
Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology Minatojima minamimachi 2 2 3, Kobe, Japan
Nucleic Acids Res 33:e43. 2005..We believe that use of this system will strongly accelerate molecular biological research using ES cells...
