Daisuke Shimosato

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. pmc Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells
    Daisuke Shimosato
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, Minatojima Minamimachi, Chuo Ku, Kobe, Hyogo, Japan
    BMC Dev Biol 7:80. 2007
  2. ncbi Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    Shinji Masui
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Minatojima minamimachi 2 2 3, Chu o ku, Kobe, Hyogo 650 0047, Japan
    Nat Cell Biol 9:625-35. 2007
  3. ncbi Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation
    Hitoshi Niwa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, 2 2 3 Minatojima minamimachi, Kobe, Hyogo 650 0047, Japan
    Cell 123:917-29. 2005
  4. doi Identification and characterization of subpopulations in undifferentiated ES cell culture
    Yayoi Toyooka
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chu o ku, Kobe, Hyogo, Japan
    Development 135:909-18. 2008
  5. ncbi Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells
    Kazuya Ogawa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Biochem Biophys Res Commun 343:159-66. 2006
  6. doi A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
    Hitoshi Niwa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 6500047, Japan
    Nature 460:118-22. 2009
  7. ncbi Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells
    Kazuya Ogawa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    J Cell Sci 120:55-65. 2007
  8. pmc An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit
    Shinji Masui
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology Minatojima minamimachi 2 2 3, Kobe, Japan
    Nucleic Acids Res 33:e43. 2005

Detail Information

Publications8

  1. pmc Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells
    Daisuke Shimosato
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, Minatojima Minamimachi, Chuo Ku, Kobe, Hyogo, Japan
    BMC Dev Biol 7:80. 2007
    ....
  2. ncbi Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    Shinji Masui
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Minatojima minamimachi 2 2 3, Chu o ku, Kobe, Hyogo 650 0047, Japan
    Nat Cell Biol 9:625-35. 2007
    ..These results indicate that the essential function of Sox2 is to stabilize ES cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression...
  3. ncbi Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation
    Hitoshi Niwa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology CDB, 2 2 3 Minatojima minamimachi, Kobe, Hyogo 650 0047, Japan
    Cell 123:917-29. 2005
    ..This suggests that reciprocal inhibition between lineage-specific transcription factors might be involved in the first differentiation event of mammalian development...
  4. doi Identification and characterization of subpopulations in undifferentiated ES cell culture
    Yayoi Toyooka
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chu o ku, Kobe, Hyogo, Japan
    Development 135:909-18. 2008
    ..These results confirmed that undifferentiated ES cell culture contains subpopulations corresponding to ICM, epiblast and PrE...
  5. ncbi Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells
    Kazuya Ogawa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Biochem Biophys Res Commun 343:159-66. 2006
    ..These observations indicate that the Wnt signal mediated by the canonical pathway is not sufficient but enhances the effect of LIF to maintain self-renewal of mouse ES cells...
  6. doi A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
    Hitoshi Niwa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 6500047, Japan
    Nature 460:118-22. 2009
    ....
  7. ncbi Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells
    Kazuya Ogawa
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    J Cell Sci 120:55-65. 2007
    ..These findings suggest that endogenously activated autocrine loops of activin-Nodal signaling promote ES cell self-renewal...
  8. pmc An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit
    Shinji Masui
    Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology Minatojima minamimachi 2 2 3, Kobe, Japan
    Nucleic Acids Res 33:e43. 2005
    ..We believe that use of this system will strongly accelerate molecular biological research using ES cells...