Hitoshi Sakakibara

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. pmc UniVIO: a multiple omics database with hormonome and transcriptome data from rice
    Toru Kudo
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama, Japan
    Plant Cell Physiol 54:e9. 2013
  2. pmc Gene expression and sensitivity in response to copper stress in rice leaves
    Emi Sudo
    RIKEN Plant Science Center, Suehiro 1 7 22, Tsurumi, Yokohama 230 0045, Japan
    J Exp Bot 59:3465-74. 2008
  3. pmc Nitrogen-dependent regulation of de novo cytokinin biosynthesis in rice: the role of glutamine metabolism as an additional signal
    Tomoe Kamada-Nobusada
    RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama, 230 0045 Japan
    Plant Cell Physiol 54:1881-93. 2013
  4. pmc Ligand-binding properties and subcellular localization of maize cytokinin receptors
    Sergey N Lomin
    Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya 35, 127276 Moscow, Russia
    J Exp Bot 62:5149-59. 2011
  5. ncbi request reprint [Cytokinin biosynthesis and novel activating pathway]
    Hitoshi Sakakibara
    Tanpakushitsu Kakusan Koso 52:1322-9. 2007
  6. ncbi request reprint Interactions between nitrogen and cytokinin in the regulation of metabolism and development
    Hitoshi Sakakibara
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Trends Plant Sci 11:440-8. 2006
  7. ncbi request reprint Cytokinins: activity, biosynthesis, and translocation
    Hitoshi Sakakibara
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Annu Rev Plant Biol 57:431-49. 2006
  8. pmc Molecular characterization of cytokinin-responsive histidine kinases in maize. Differential ligand preferences and response to cis-zeatin
    Keiko Yonekura-Sakakibara
    Plant Science Center, RIKEN, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Plant Physiol 134:1654-61. 2004
  9. doi request reprint Side-chain modification of cytokinins controls shoot growth in Arabidopsis
    Takatoshi Kiba
    RIKEN Center for Sustainable Resource Science, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Dev Cell 27:452-61. 2013
  10. doi request reprint Metabolomic screening applied to rice FOX Arabidopsis lines leads to the identification of a gene-changing nitrogen metabolism
    Doris Albinsky
    RIKEN Plant Science Center, Tsurumi ku, Yokohama, Japan
    Mol Plant 3:125-42. 2010

Detail Information

Publications74

  1. pmc UniVIO: a multiple omics database with hormonome and transcriptome data from rice
    Toru Kudo
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama, Japan
    Plant Cell Physiol 54:e9. 2013
    ..In the correlation search, calculation method, range of correlation coefficient and plant samples can be selected freely...
  2. pmc Gene expression and sensitivity in response to copper stress in rice leaves
    Emi Sudo
    RIKEN Plant Science Center, Suehiro 1 7 22, Tsurumi, Yokohama 230 0045, Japan
    J Exp Bot 59:3465-74. 2008
    ....
  3. pmc Nitrogen-dependent regulation of de novo cytokinin biosynthesis in rice: the role of glutamine metabolism as an additional signal
    Tomoe Kamada-Nobusada
    RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama, 230 0045 Japan
    Plant Cell Physiol 54:1881-93. 2013
    ..We conclude that plants possess multiple regulation systems for nitrogen-dependent cytokinin biosynthesis to modulate growth in response to nitrogen availability. ..
  4. pmc Ligand-binding properties and subcellular localization of maize cytokinin receptors
    Sergey N Lomin
    Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya 35, 127276 Moscow, Russia
    J Exp Bot 62:5149-59. 2011
    ..This was corroborated by observations of the subcellular localization of ZmHK1 fusions with green fluorescent protein in maize protoplasts. All these data strongly suggest that at least a part of cytokinin perception occurs in the ER...
  5. ncbi request reprint [Cytokinin biosynthesis and novel activating pathway]
    Hitoshi Sakakibara
    Tanpakushitsu Kakusan Koso 52:1322-9. 2007
  6. ncbi request reprint Interactions between nitrogen and cytokinin in the regulation of metabolism and development
    Hitoshi Sakakibara
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Trends Plant Sci 11:440-8. 2006
    ..The coordination and interaction of both regulatory pathways is important for normal plant growth under variable nitrogen supply conditions...
  7. ncbi request reprint Cytokinins: activity, biosynthesis, and translocation
    Hitoshi Sakakibara
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Annu Rev Plant Biol 57:431-49. 2006
    ....
  8. pmc Molecular characterization of cytokinin-responsive histidine kinases in maize. Differential ligand preferences and response to cis-zeatin
    Keiko Yonekura-Sakakibara
    Plant Science Center, RIKEN, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Plant Physiol 134:1654-61. 2004
    ..These results strongly suggest that maize cytokinin receptors differ in ligand preference, and that cZ is an active cytokinin at least in maize...
  9. doi request reprint Side-chain modification of cytokinins controls shoot growth in Arabidopsis
    Takatoshi Kiba
    RIKEN Center for Sustainable Resource Science, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Dev Cell 27:452-61. 2013
    ..We propose that the control of cytokinin function by side-chain modification is crucial for shoot growth regulation in plants. ..
  10. doi request reprint Metabolomic screening applied to rice FOX Arabidopsis lines leads to the identification of a gene-changing nitrogen metabolism
    Doris Albinsky
    RIKEN Plant Science Center, Tsurumi ku, Yokohama, Japan
    Mol Plant 3:125-42. 2010
    ..Thus, the combination of a metabolomics-based screening method and a gain-of-function approach is useful for rapid characterization of novel genes in both Arabidopsis and rice...
  11. pmc Cytokinin activity of cis-zeatin and phenotypic alterations induced by overexpression of putative cis-Zeatin-O-glucosyltransferase in rice
    Toru Kudo
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Plant Physiol 160:319-31. 2012
    ..These results propose that cZ activity has a physiological impact on the growth and development of rice...
  12. pmc Agrobacterium tumefaciens tumor morphology root plastid localization and preferential usage of hydroxylated prenyl donor is important for efficient gall formation
    Nanae Ueda
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Plant Physiol 159:1064-72. 2012
    ..Tmr is thus specialized for plastid localization and preferential usage of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate in vivo and is important for efficient gall formation...
  13. pmc Structural insight into the reaction mechanism and evolution of cytokinin biosynthesis
    Hajime Sugawara
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Proc Natl Acad Sci U S A 105:2734-9. 2008
    ..Despite structural similarities, IPT has evolved a distinct role in which the p loop transfers a prenyl moiety in cytokinin biosynthesis...
  14. pmc RiceFOX: a database of Arabidopsis mutant lines overexpressing rice full-length cDNA that contains a wide range of trait information to facilitate analysis of gene function
    Tetsuya Sakurai
    RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, 230 0045 Japan
    Plant Cell Physiol 52:265-73. 2011
    ..The RiceFOX database is available at http://ricefox.psc.riken.jp/...
  15. ncbi request reprint AtIPT3 is a key determinant of nitrate-dependent cytokinin biosynthesis in Arabidopsis
    Kentaro Takei
    Plant Science Center, RIKEN Institute of Physical and Chemical Research, Suehiro 1 7 22, Tsurumi, Yokohama, 230 0045 Japan
    Plant Cell Physiol 45:1053-62. 2004
    ..These results suggest that nitrogen availability differentially regulates expression of AtIPT3 and AtIPT5, and that AtIPT3 is a key determinant of cytokinin biosynthesis in response to rapid changes in the availability of NO(3)(-)...
  16. pmc Highly sensitive and high-throughput analysis of plant hormones using MS-probe modification and liquid chromatography-tandem mass spectrometry: an application for hormone profiling in Oryza sativa
    Mikiko Kojima
    RIKEN Plant Science Center, Tsurumi, Yokohama, Japan
    Plant Cell Physiol 50:1201-14. 2009
    ..Combining the results of hormone profiling data with transcriptome data in the gibberellin signaling mutants allows us to analyze relationships between changes in gene expression and hormone metabolism...
  17. pmc Functional characterization and expression analysis of a gene, OsENT2, encoding an equilibrative nucleoside transporter in rice suggest a function in cytokinin transport
    Naoya Hirose
    RIKEN The Institute of Physical and Chemical Research Plant Science Center, Tsurumi ku, Yokohama 230 0045, Japan
    Plant Physiol 138:196-206. 2005
    ....
  18. ncbi request reprint Overexpression of a type-A response regulator alters rice morphology and cytokinin metabolism
    Naoya Hirose
    RIKEN Plant Science Center, 1 7 22, Suehiro, Tsurumi, Yokohama, 230 0045, Japan
    Plant Cell Physiol 48:523-39. 2007
    ..Expression of genes encoding CK oxidase/dehydrogenase decreased in OsRR6-ox plants, possibly accounting for elevated CK levels in transgenic lines. Expression of a number of stress response genes was also altered in OsRR6-ox plants...
  19. pmc Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis
    Takeshi Kuroha
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Plant Cell 21:3152-69. 2009
    ..Our results strongly suggest that the direct activation pathway via LOGs plays a pivotal role in regulating cytokinin activity during normal growth and development in Arabidopsis...
  20. doi request reprint Hormonal control of nitrogen acquisition: roles of auxin, abscisic acid, and cytokinin
    Takatoshi Kiba
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    J Exp Bot 62:1399-409. 2011
    ..In this review, the evidence is summarized, mostly focusing on examples related to nitrogen acquisition...
  21. ncbi request reprint Systematic approaches to using the FOX hunting system to identify useful rice genes
    Youichi Kondou
    RIKEN Plant Science Center, Yokohama, Kanagawa, Japan
    Plant J 57:883-94. 2009
    ..This technology provides a framework for the analysis of plant gene function in a heterologous host and of plant improvement by using heterologous gene resources...
  22. pmc PSEUDO-RESPONSE REGULATORS 9, 7, and 5 are transcriptional repressors in the Arabidopsis circadian clock
    Norihito Nakamichi
    RIKEN Plant Science Center, Plant Productivity Systems Research Group, Tsurumi, Yokohama 230 0045, Japan
    Plant Cell 22:594-605. 2010
    ..These results suggest that the repressor activities of PRR9, PRR7, and PRR5 on the CCA1 and LHY promoter regions constitute the molecular mechanism that accounts for the role of these proteins in the feedback loop of the circadian clock...
  23. pmc Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant
    Hitoshi Sakakibara
    Laboratories for Communication Mechanisms and Cellular Growth and Development, Plant Science Center, RIKEN, Suehiro 1 7 22, Tsurumi, Yokohama 230 0045, Japan
    Proc Natl Acad Sci U S A 102:9972-7. 2005
    ..These results demonstrate that A. tumefaciens modifies CK biosynthesis by sending a key enzyme into plastids of the host plant to promote tumorigenesis...
  24. pmc Analysis of cytokinin mutants and regulation of cytokinin metabolic genes reveals important regulatory roles of cytokinins in drought, salt and abscisic acid responses, and abscisic acid biosynthesis
    Rie Nishiyama
    RIKEN Plant Science Center, Yokohama, Kanagawa 230 0045, Japan
    Plant Cell 23:2169-83. 2011
    ....
  25. doi request reprint Molecular basis for cytokinin biosynthesis
    Tomoe Kamada-Nobusada
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Phytochemistry 70:444-9. 2009
    ..Collectively, these advances have revealed the complexity of the entire metabolic scheme for CK biosynthesis...
  26. ncbi request reprint Molecular characterization of His-Asp phosphorelay signaling factors in maize leaves: implications of the signal divergence by cytokinin-inducible response regulators in the cytosol and the nuclei
    Yasuharu Asakura
    Plant Science Center, RIKEN Institute of Physical and Chemical Research, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Plant Mol Biol 52:331-41. 2003
    ....
  27. ncbi request reprint Regulation of cytokinin biosynthesis, compartmentalization and translocation
    Naoya Hirose
    RIKEN Plant Science Center, Suehiro 1 7 22, Tsurumi, Yokohama 230 0045, Japan
    J Exp Bot 59:75-83. 2008
    ..These biochemical and transgenic data suggest that AtENT6, an Arabidopsis ENT, could also participate in cytokinin nucleoside transport with a preference for iP riboside in vascular tissue...
  28. pmc Destination-selective long-distance movement of phloem proteins
    Koh Aoki
    Plant Science Center, RIKEN, Institute of Physical and Chemical Research, Tsurumi, Yokohama 230 0045, Japan
    Plant Cell 17:1801-14. 2005
    ....
  29. pmc Impact of clock-associated Arabidopsis pseudo-response regulators in metabolic coordination
    Atsushi Fukushima
    RIKEN Plant Science Center, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    Proc Natl Acad Sci U S A 106:7251-6. 2009
    ..These findings indicated that mitochondrial functions are coupled with the circadian system in plants...
  30. ncbi request reprint Arabidopsis CYP735A1 and CYP735A2 encode cytokinin hydroxylases that catalyze the biosynthesis of trans-Zeatin
    Kentaro Takei
    Plant Science Center, RIKEN, Suehiro 1 7 22, Tsurumi, Yokohama 230 0045, Japan
    J Biol Chem 279:41866-72. 2004
    ..Root-specific induction of CYP735A2 expression by CK suggests that the trans-hydroxylation is involved in the regulation of CK metabolism and signaling in roots...
  31. doi request reprint Uniconazole, a cytochrome P450 inhibitor, inhibits trans-zeatin biosynthesis in Arabidopsis
    Eriko Sasaki
    RIKEN Plant Science Center, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Phytochemistry 87:30-8. 2013
    ..As a result of these screenings, it was found that uniconazole, a well known inhibitor of cytochrome P450 monooxygenase, prevents the biosynthesis of trans-zeatin, and that its target is CYP735As in Arabidopsis...
  32. pmc Crystallization and preliminary X-ray diffraction study of the histidine-containing phosphotransfer protein ZmHP1 from maize
    Hajime Sugawara
    Laboratory for Communication Mechanisms, RIKEN Plant Science Center, Yokohama 230 0045, Japan
    Acta Crystallogr Sect F Struct Biol Cryst Commun 61:366-8. 2005
    ..4 A resolution. The crystals belonged to the space group P4(1)2(1)2, with one ZmHP1 molecule in the asymmetric unit...
  33. doi request reprint Arabidopsis lonely guy (LOG) multiple mutants reveal a central role of the LOG-dependent pathway in cytokinin activation
    Hiroki Tokunaga
    RIKEN Plant Science Center, 1 7 22, Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Plant J 69:355-65. 2012
    ..These results suggest a dominant role of the single-step activation pathway mediated by LOGs for cytokinin production, and overlapping but differentiated functions of the members of the LOG gene family in growth and development...
  34. ncbi request reprint Phytochromes and cryptochromes regulate the differential growth of Arabidopsis hypocotyls in both a PGP19-dependent and a PGP19-independent manner
    Akitomo Nagashima
    RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    Plant J 53:516-29. 2008
    ..These data suggest that the control of auxin transport by phytochromes and cryptochromes is a critical regulatory component of hypocotyl growth in response to light...
  35. pmc Regulatory roles of cytokinins and cytokinin signaling in response to potassium deficiency in Arabidopsis
    Youn Jeong Nam
    RIKEN Plant Science Center, Yokohama, Kanagawa, Japan
    PLoS ONE 7:e47797. 2012
    ..From these results, we conclude that a reduction in CK levels subsequently allows fast and effective stimulation of low K-induced ROS accumulation, root hair growth and HAK5 expression, leading to plant adaptation to low K conditions...
  36. pmc Crystal structure of the histidine-containing phosphotransfer protein ZmHP2 from maize
    Hajime Sugawara
    Laboratory for Communication Mechanisms, RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama 230 0045, Japan
    Protein Sci 14:202-8. 2005
    ..In bacteria, it is replaced by glutamine or glutamate that form a hydrogen bond to Ndelta atoms of the phospho-accepting histidine. It may play a key role in the complex formation of ZmHP2 with receiver domains...
  37. ncbi request reprint A method for separation and determination of cytokinin nucleotides from plant tissues
    Kentaro Takei
    Plant Science Center, RIKEN The Institute of Physical and Chemical Research, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    J Plant Res 116:265-9. 2003
    ..This method enabled us to analyze the amount of each species of cytokinin nucleotide in plant tissues...
  38. doi request reprint The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access
    Hideki Goda
    RIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Plant J 55:526-42. 2008
    ..The data set presented here will be a versatile resource for future hormone studies, and constitutes a reference for genome-wide gene expression in Arabidopsis...
  39. doi request reprint Metabolism and long-distance translocation of cytokinins
    Toru Kudo
    RIKEN Plant Science Center, Yokohama, Kanagawa, 230 0045, Japan
    J Integr Plant Biol 52:53-60. 2010
    ..Here, to gain insight into this elaborate signaling system, we summarize current models of biosynthesis, trans-membrane transport, and long-distance translocation of cytokinins in higher plants...
  40. doi request reprint Highly sensitive high-throughput profiling of six phytohormones using MS-probe modification and liquid chromatography-tandem mass spectrometry
    Mikiko Kojima
    RIKEN Plant Science Center, Tsurumi, Yokohama, Japan
    Methods Mol Biol 918:151-64. 2012
    ..The method requires plant tissue of <100 mg fresh weight for quantification and enables us to analyze large number of plant samples at a time...
  41. pmc The Arabidopsis nitrate transporter NRT2.4 plays a double role in roots and shoots of nitrogen-starved plants
    Takatoshi Kiba
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Plant Cell 24:245-58. 2012
    ..4 (triple mutants) has an impact on biomass production under low nitrate supply. Together, our results demonstrate that NRT2.4 is a nitrate transporter that has a role in both roots and shoots under N starvation...
  42. ncbi request reprint A new method for enzymatic preparation of isopentenyladenine-type and trans-zeatin-type cytokinins with radioisotope-labeling
    Kentaro Takei
    Plant Science Center, RIKEN The Institute of Physical and Chemical Research, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    J Plant Res 116:259-63. 2003
    ..These labeled compounds will be useful tools for cytokinin research, such as receptor-ligand assays and cell metabolism studies...
  43. ncbi request reprint Nitrate-specific and cytokinin-mediated nitrogen signaling pathways in plants
    Hitoshi Sakakibara
    Plant Science Center, RIKEN The Institute of Physical and Chemical Research, 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    J Plant Res 116:253-7. 2003
    ..The coordination of both regulatory pathways seems to be crucially important for the integration of nitrogen signals at the whole plant level...
  44. doi request reprint Transcript profiling of an Arabidopsis PSEUDO RESPONSE REGULATOR arrhythmic triple mutant reveals a role for the circadian clock in cold stress response
    Norihito Nakamichi
    Division of Biological Science, Graduate School of Science, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8602, Japan
    Plant Cell Physiol 50:447-62. 2009
    ..These results suggest that PRR9, PRR7 and PRR5 are involved in a mechanism that anticipates diurnal cold stress and which initiates a stress response by mediating cyclic expression of stress response genes, including DREB1/CBF...
  45. doi request reprint Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids
    Ryo Nakabayashi
    RIKEN Center for Sustainable Resource Science, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, 230 0045, Japan Graduate School of Pharmaceutical Sciences, Chiba University, 1 8 1 Chuo ku, Chiba, 260 8675, Japan CREST, Japan Science and Technology Agency, 4 1 8 Honcho, Kawaguchi, Saitama, 332 0012, Japan
    Plant J 77:367-79. 2014
    ..These data confirm the usefulness of flavonoids for enhancing both biotic and abiotic stress tolerance in crops. ..
  46. pmc Integrated analysis of transcriptome and metabolome of Arabidopsis albino or pale green mutants with disrupted nuclear-encoded chloroplast proteins
    Masakazu Satou
    Plant Science Center Center for Sustainable Resource Science, RIKEN, Yokohama, Kanagawa, 230 0045, Japan
    Plant Mol Biol 85:411-28. 2014
    ..In albino mutants, the alteration of metabolites accumulation and genes expression is stronger than pale green mutants. ..
  47. ncbi request reprint Cytokinin biosynthesis and regulation
    Hitoshi Sakakibara
    Plant Science Center, RIKEN 1 7 22 Suehiro, Tsurumi, Yokohama 230 0045, Japan
    Vitam Horm 72:271-87. 2005
    ..This regulatory system appears important in linking nutrient signals and morphogenetic responses...
  48. pmc Targeted degradation of PSEUDO-RESPONSE REGULATOR5 by an SCFZTL complex regulates clock function and photomorphogenesis in Arabidopsis thaliana
    Takatoshi Kiba
    Laboratory of Plant Molecular Biology, The Rockefeller University, New York, New York 10065 6399, USA
    Plant Cell 19:2516-30. 2007
    ..Together, our results show that ZTL targets PRR5 for degradation by 26S proteasomes in the circadian clock and in early photomorphogenesis...
  49. ncbi request reprint Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry
    Takatoshi Kiba
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya, 464 8601 Japan
    Plant Cell Physiol 46:339-55. 2005
    ..Including these, the presented list of cytokinin-up-regulated genes (214) will provide us with valuable bases for understanding the His-->Asp phosphorelay in A. thaliana...
  50. ncbi request reprint Overexpression of a petunia zinc-finger gene alters cytokinin metabolism and plant forms
    Hitoshi Nakagawa
    Developmental Biology Laboratory, Plant Physiology Department, National Institute of Agrobiological Sciences, 2 1 2 Kannondai, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 41:512-23. 2005
    ..On the basis of these results we discuss about possible functions of LIF...
  51. ncbi request reprint Arabidopsis response regulator, ARR22, ectopic expression of which results in phenotypes similar to the wol cytokinin-receptor mutant
    Takatoshi Kiba
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya, 464 8601 Japan
    Plant Cell Physiol 45:1063-77. 2004
    ..These results suggested that ARR22 might also be implicated, directly or indirectly, in the cytokinin-responsive His-->Asp phophorelay signal transduction...
  52. ncbi request reprint Accumulation of maize response regulator proteins in mesophyll cells after cytokinin treatment
    Atsushi Deji
    Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Japan
    Biosci Biotechnol Biochem 66:1853-8. 2002
    ..These results suggest that ZmRR1 and ZmRR2 are induced in mesophyll cells and function in nitrogen signal transduction mediated by cytokinin...
  53. ncbi request reprint Regulation of sulfur-responsive gene expression by exogenously applied cytokinins in Arabidopsis thaliana
    Naoko Ohkama
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, 113 8657 Japan
    Plant Cell Physiol 43:1493-501. 2002
    ....
  54. ncbi request reprint Direct control of shoot meristem activity by a cytokinin-activating enzyme
    Takashi Kurakawa
    Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi, Bunkyo, Tokyo 113 8652, Japan
    Nature 445:652-5. 2007
    ..We propose the fine-tuning of concentrations and the spatial distribution of bioactive cytokinins by a cytokinin-activating enzyme as a mechanism that regulates meristem activity...
  55. ncbi request reprint [Communication mechanisms of nitrogen signal transduction in plants]
    Hitoshi Sakakibara
    Tanpakushitsu Kakusan Koso 48:2006-13. 2003
  56. doi request reprint Constitutive activation of a CC-NB-LRR protein alters morphogenesis through the cytokinin pathway in Arabidopsis
    Kadunari Igari
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara 630 0192, Japan
    Plant J 55:14-27. 2008
    ..From these data, we propose that the modification of the cytokinin pathway might be involved in some R protein-mediated responses...
  57. ncbi request reprint Type-B ARR transcription factors, ARR10 and ARR12, are implicated in cytokinin-mediated regulation of protoxylem differentiation in roots of Arabidopsis thaliana
    Akihiro Yokoyama
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Furocho, Chikusa, Nagoya, 464 8601 Japan
    Plant Cell Physiol 48:84-96. 2007
    ..Taken together, we propose that ARR10 and ARR12, together with ARR1, redundantly play pivotal roles in the AHK-dependent phosphorelay signaling in response to cytokinin in roots...
  58. ncbi request reprint Cytokinin receptors are required for normal development of auxin-transporting vascular tissues in the hypocotyl but not in adventitious roots
    Takeshi Kuroha
    Institute of Biological Sciences, University of Tsukuba, Tsukuba, 305 8572 Japan
    Plant Cell Physiol 47:234-43. 2006
    ..Our results suggest that cytokinin receptors are necessary for the formation of auxin-transporting vascular tissues in the hypocotyl, but not in adventitious roots...
  59. ncbi request reprint Auxin controls local cytokinin biosynthesis in the nodal stem in apical dominance
    Mina Tanaka
    Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa, Nagoya 464 8601, Japan
    Plant J 45:1028-36. 2006
    ....
  60. ncbi request reprint A link between cytokinin and ASL9 (ASYMMETRIC LEAVES 2 LIKE 9) that belongs to the AS2/LOB (LATERAL ORGAN BOUNDARIES) family genes in Arabidopsis thaliana
    Takahito Naito
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Nagoya, Japan
    Biosci Biotechnol Biochem 71:1269-78. 2007
    ..Taken together, the results of this study suggest that the cytokinin-induced ASL9 gene is implicated in regulation of the development of Arabidopsis thaliana...
  61. ncbi request reprint Multiple routes communicating nitrogen availability from roots to shoots: a signal transduction pathway mediated by cytokinin
    Kentaro Takei
    Laboratory for Communication Mechanism, Plant Science Center, RIKEN The Institute of Physical and Chemical Research Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    J Exp Bot 53:971-7. 2002
    ..Thus, in addition to nitrate, cytokinin could be another root-to-shoot signal communicating nitrogen availability...
  62. doi request reprint A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana
    Tomoe Kamada-Nobusada
    Division of Cell Mechanisms, Department of Cell Biology, National Institute for Basic Biology, Okazaki, 444 8585 Japan
    Plant Cell Physiol 49:1272-82. 2008
    ..Microarray analysis showed that AtPAO4 deficiency induced alterations in the expression of genes related to the drought stress response and flavonoid biosynthesis...
  63. pmc Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice
    Ko Hirano
    Bioscience and Biotechnology Center, Nagoya University, Nagoya, 464 8601 Japan
    Plant Cell Physiol 49:1429-50. 2008
    ....
  64. ncbi request reprint Differential response of genes for ferredoxin and ferredoxin:NADP+ oxidoreductase to nitrate and light in maize leaves
    Hitoshi Sakakibara
    Plant Science Center, RIKEN The Institute of Physical and Chemical Research, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    J Plant Physiol 160:65-70. 2003
    ....
  65. ncbi request reprint Identification and characterization of a gene encoding drought-inducible protein localizing in the bundle sheath cell of sugarcane
    Bambang Sugiharto
    Research Center for Molecular Biology, University of Jember, Jl Kalimantan III 23, Jember, 68121, Indonesia
    Plant Cell Physiol 43:350-4. 2002
    ..These results suggest that SoDip22 functions to adapt to drought stress in the bundle sheath cell, and that the signaling pathway for the induction is, at least in a part, mediated by ABA...
  66. pmc The GID1-mediated gibberellin perception mechanism is conserved in the Lycophyte Selaginella moellendorffii but not in the Bryophyte Physcomitrella patens
    Ko Hirano
    Bioscience and Biotechnology Center, Nagoya University, Nagoya 464 8601, Japan
    Plant Cell 19:3058-79. 2007
    ..patens, indicating that GID1/DELLA-mediated GA signaling, if present, differs from that in vascular plants. Our results suggest that GID1/DELLA-mediated GA signaling appeared after the divergence of vascular plants from the moss lineage...
  67. pmc Delayed leaf senescence induces extreme drought tolerance in a flowering plant
    Rosa M Rivero
    Department of Plant Sciences, University of California, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 104:19631-6. 2007
    ..The production of drought-tolerant crops able to grow under restricted water regimes without diminution of yield would minimize drought-related losses and ensure food production in water-limited lands...
  68. ncbi request reprint AHK5 histidine kinase regulates root elongation through an ETR1-dependent abscisic acid and ethylene signaling pathway in Arabidopsis thaliana
    Ayako Iwama
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Furocho, Chikusa ku, Nagoya, Japan
    Plant Cell Physiol 48:375-80. 2007
    ..Our results suggest that AHK5 His-kinase acts as a negative regulator in the signaling pathway in which ethylene and ABA inhibit the root elongation through ETR1 (an ethylene receptor)...
  69. ncbi request reprint Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis
    Hiroyuki Kasahara
    Laboratory for Cellular Growth and Development, Plant Science Center, RIKEN, Yokohoma, Japan
    J Biol Chem 279:14049-54. 2004
    ..Distinct origins of large proportions of DMAPP for tZ and cZ biosynthesis suggest that plants are able to separately modulate the level of these cytokinin species...
  70. ncbi request reprint CHRK1, a chitinase-related receptor-like kinase, plays a role in plant development and cytokinin homeostasis in tobacco
    Jeong Hee Lee
    Laboratory of Plant Genomics, Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon 305 333, Korea
    Plant Mol Biol 53:877-90. 2003
    ..Based on these results, we propose that CHRK1 is involved in a developmental signaling pathway regulating cell proliferation/differentiation and the endogenous cytokinin levels in tobacco...
  71. ncbi request reprint Cytokinin oxidase regulates rice grain production
    Motoyuki Ashikari
    Bioscience and Biotechnology Center, Nagoya University, Nagoya 464 8601, Japan
    Science 309:741-5. 2005
    ..QTL pyramiding to combine loci for grain number and plant height in the same genetic background generated lines exhibiting both beneficial traits. These results provide a strategy for tailormade crop improvement...
  72. pmc Ectopic expression of KNOTTED1-like homeobox protein induces expression of cytokinin biosynthesis genes in rice
    Tomoaki Sakamoto
    Field Production Science Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Nishi Tokyo, Tokyo 188 0002, Japan
    Plant Physiol 142:54-62. 2006
    ....
  73. pmc Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production
    Antoine Martin
    Unité de Nutrition Azotée des Plantes UR511, Institut National de la Recherche Agronomique, F 78026 Versailles Cedex, France
    Plant Cell 18:3252-74. 2006
    ..The two GS1 isoenzymes play nonredundant roles with respect to their tissue-specific localization...
  74. pmc Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition
    Machteld C Mok
    Department of Horticulture and Center for Gene Research and Biotechnology, Oregon State University, Corvallis, Oregon 97331 7304, USA
    Plant Physiol 137:1057-66. 2005
    ..The AHK4 receptor responded to trans-zeatin and m-topolin, while the ZmHK1 receptor responded also to cis-zeatin and o-topolin. Three-dimensional molecular models of the substrates were applied to explain the results...