Hitoshi Okamoto

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. doi request reprint Neurobiology: sensory lateralization in the fish brain
    Hitoshi Okamoto
    RIKEN Brain Science Institute, Saitama 351 0198, Japan Electronic address
    Curr Biol 24:R285-7. 2014
  2. doi request reprint Fear and anxiety regulation by conserved affective circuits
    Hitoshi Okamoto
    RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Neuron 78:411-3. 2013
  3. doi request reprint Genetic dissection of the zebrafish habenula, a possible switching board for selection of behavioral strategy to cope with fear and anxiety
    Hitoshi Okamoto
    RIKEN Brain Science Institute, Saitama, Japan
    Dev Neurobiol 72:386-94. 2012
  4. ncbi request reprint [The Islet-1 family in subtype specification of motor neurons]
    Hitoshi Okamoto
    Tanpakushitsu Kakusan Koso 49:241-6. 2004
  5. doi request reprint Transgenic technology for visualization and manipulation of the neural circuits controlling behavior in zebrafish
    Hitoshi Okamoto
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Dev Growth Differ 50:S167-75. 2008
  6. ncbi request reprint Yin-yang ways of controlling gene expression are now in our hands
    Hitoshi Okamoto
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    ACS Chem Biol 2:646-8. 2007
  7. doi request reprint Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells
    Shinya Ohata
    RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Neuron 69:215-30. 2011
  8. doi request reprint The habenula is crucial for experience-dependent modification of fear responses in zebrafish
    Masakazu Agetsuma
    RIKEN Brain Science Institute, Wako, Saitama, Japan
    Nat Neurosci 13:1354-6. 2010
  9. ncbi request reprint PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching
    Toshio Miyashita
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako, Saitama 351 0198, Japan
    Development 131:3705-15. 2004
  10. doi request reprint Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula
    Ryunosuke Amo
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Neurosci 30:1566-74. 2010

Collaborators

Detail Information

Publications56

  1. doi request reprint Neurobiology: sensory lateralization in the fish brain
    Hitoshi Okamoto
    RIKEN Brain Science Institute, Saitama 351 0198, Japan Electronic address
    Curr Biol 24:R285-7. 2014
    ..New research shows that the left and right habenula differentially process visual and olfactory information. Spontaneous activity in habenular circuits may lead to activation of distinct neuronal targets and behavioral programs. ..
  2. doi request reprint Fear and anxiety regulation by conserved affective circuits
    Hitoshi Okamoto
    RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Neuron 78:411-3. 2013
    ....
  3. doi request reprint Genetic dissection of the zebrafish habenula, a possible switching board for selection of behavioral strategy to cope with fear and anxiety
    Hitoshi Okamoto
    RIKEN Brain Science Institute, Saitama, Japan
    Dev Neurobiol 72:386-94. 2012
    ..Our observation supports that the habenula may act as the multimodal switching board for controlling emotional behaviors and/or memory inexperience dependent manners...
  4. ncbi request reprint [The Islet-1 family in subtype specification of motor neurons]
    Hitoshi Okamoto
    Tanpakushitsu Kakusan Koso 49:241-6. 2004
  5. doi request reprint Transgenic technology for visualization and manipulation of the neural circuits controlling behavior in zebrafish
    Hitoshi Okamoto
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Dev Growth Differ 50:S167-75. 2008
    ..These insights emphasize the benefits of applying advanced transgenic technology in zebrafish to future research into this area...
  6. ncbi request reprint Yin-yang ways of controlling gene expression are now in our hands
    Hitoshi Okamoto
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    ACS Chem Biol 2:646-8. 2007
    ..Their dream is now coming true thanks to the transparency of the embryonic body of the zebrafish ( Danio rerio), which has made gene manipulation by photoillumination possible...
  7. doi request reprint Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells
    Shinya Ohata
    RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Neuron 69:215-30. 2011
    ....
  8. doi request reprint The habenula is crucial for experience-dependent modification of fear responses in zebrafish
    Masakazu Agetsuma
    RIKEN Brain Science Institute, Wako, Saitama, Japan
    Nat Neurosci 13:1354-6. 2010
    ....
  9. ncbi request reprint PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching
    Toshio Miyashita
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako, Saitama 351 0198, Japan
    Development 131:3705-15. 2004
    ....
  10. doi request reprint Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula
    Ryunosuke Amo
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Neurosci 30:1566-74. 2010
    ..These findings indicated that the lateral habenular pathways are evolutionarily conserved pathways and might control adaptive behaviors in vertebrates through the regulation of monoaminergic activities...
  11. ncbi request reprint Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos
    Hironori Wada
    Laboratory for Developmental Gene Regulation, Brain Science Institute, The Institute of Physical and Chemical Research RIKEN Saitama 351 0198, Japan
    Development 132:2273-85. 2005
    ..The dual roles of the scrb1 gene in both neuronal migration and CE provide a novel insight into the underlying mechanisms of cell movement in vertebrate development...
  12. doi request reprint Imaging of neural ensemble for the retrieval of a learned behavioral program
    Tazu Aoki
    RIKEN Brain Science Institute, 351 0198 Wako, Japan
    Neuron 78:881-94. 2013
    ..Moreover, the findings indicate that consolidated memory traces can be rapidly modified during reinforcement learning...
  13. ncbi request reprint The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation
    Ichiro Masai
    Masai Initiative Research Unit, RIKEN The Institute of Physical and Chemical Research, Hirosawa, Saitama, Japan
    Development 132:1539-53. 2005
    ..This dual requirement of Hh signalling in RGC differentiation implies that the regulation of a neurogenic wave is more complex in the zebrafish retina than in the Drosophila eye...
  14. ncbi request reprint Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain
    Hironori Wada
    Laboratory for Developmental Gene Regulation, Brain Science Institute, The Institute of Physical and Chemical Research RIKEN Saitama 351 0198, Japan
    Development 133:4749-59. 2006
    ..e. preventing integration of differentiated neurons into the neuroepithelial layer). This contrasts markedly with their reported role in reintegration of neuroepithelial daughter cells into the neuroepithelial layer after cell division...
  15. doi request reprint Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons
    Hideomi Tanaka
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute BSI, Saitama, Japan
    Dev Dyn 240:9-22. 2011
    ..These data indicate that Dpysl3 is cooperating with Sema3d in the peripheral axon outgrowth, and Isl1 is required for the selective outgrowth of the peripheral axons of RB neurons by maintaining the expression of dpysl3...
  16. pmc Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus
    Hidenori Aizawa
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Curr Biol 15:238-43. 2005
    ....
  17. ncbi request reprint Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures
    Hidenori Aizawa
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Dev Cell 12:87-98. 2007
    ..Genetic hyperactivation and repression of Notch signaling revealed that differential timing determines both specificity and asymmetry in the neurogenesis of neural precursors for the habenular subnuclei...
  18. doi request reprint Neuroepithelial cells require fucosylated glycans to guide the migration of vagus motor neuron progenitors in the developing zebrafish hindbrain
    Shinya Ohata
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Saitama, Japan
    Development 136:1653-63. 2009
    ..Together, these findings suggest that fucosylated glycans expressed in neuroepithelial cells are required to guide the migration of vagus motor neuron progenitors...
  19. ncbi request reprint Visualization of two distinct classes of neurons by gad2 and zic1 promoter/enhancer elements in the dorsal hindbrain of developing zebrafish reveals neuronal connectivity related to the auditory and lateral line systems
    Takayuki Sassa
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama, Japan
    Dev Dyn 236:706-18. 2007
    ..Comparison of these projections with those from the cochlear nuclei to the inferior colliculus in mammals suggests similarities across vertebrate species...
  20. ncbi request reprint Novel mutations affecting axon guidance in zebrafish and a role for plexin signalling in the guidance of trigeminal and facial nerve axons
    Hideomi Tanaka
    Laboratory for Developmental Gene Regulation, Brain Science Institute, The Institute of Physical and Chemical Research RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Development 134:3259-69. 2007
    ....
  21. ncbi request reprint Robo2 is required for establishment of a precise glomerular map in the zebrafish olfactory system
    Nobuhiko Miyasaka
    Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Development 132:1283-93. 2005
    ..These data provide functional evidence for Robo2/Slit signaling in the establishment of olfactory neural circuitry in zebrafish...
  22. ncbi request reprint Lhx2 mediates the activity of Six3 in zebrafish forebrain growth
    Hideki Ando
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, Wako, Saitama 351 0198, Japan
    Dev Biol 287:456-68. 2005
    ..Our results suggest that Lhx2 may mediate an alternative or parallel pathway for control of cellular proliferation in the developing forebrain via Six3...
  23. ncbi request reprint Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression
    Osamu Uemura
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Dev Biol 278:587-606. 2005
    ....
  24. doi request reprint From the olfactory bulb to higher brain centers: genetic visualization of secondary olfactory pathways in zebrafish
    Nobuhiko Miyasaka
    Laboratories for Neurobiology of Synapse, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Neurosci 29:4756-67. 2009
    ..Moreover, our finding of asymmetric bulbo-habenular projection renders the olfactory system an attractive model for the studies of brain asymmetry and lateralized behaviors...
  25. pmc Illuminating cell-cycle progression in the developing zebrafish embryo
    Mayu Sugiyama
    Laboratory for Cell Function and Dynamics, Advanced Technology Development Group, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako City, Saitama 351 0198, Japan
    Proc Natl Acad Sci U S A 106:20812-7. 2009
    ..Our study demonstrates the effectiveness of using the Cul4(Ddb1)-mediated Cdt1 degradation pathway common to all metazoans for the development of a G(1) marker that works in the nonmammalian animal model...
  26. ncbi request reprint Genetic single-cell mosaic analysis implicates ephrinB2 reverse signaling in projections from the posterior tectum to the hindbrain in zebrafish
    Tomomi Sato
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, Wako, Saitama 351 0198, Japan
    J Neurosci 27:5271-9. 2007
    ..These results may provide a neuroanatomical and molecular basis for the motor command map in the tectum...
  27. ncbi request reprint HuC:Kaede, a useful tool to label neural morphologies in networks in vivo
    Tomomi Sato
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, Japan
    Genesis 44:136-42. 2006
    ..These data indicate that Kaede is a useful tool to selectively label neural networks in zebrafish...
  28. ncbi request reprint Photo-mediated gene activation by using caged mRNA in zebrafish embryos
    Hideki Ando
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN The Institute of Physical and Chemical Research, Saitama 351 0198, Japan
    Methods Cell Biol 77:159-71. 2004
  29. doi request reprint Transgenic zebrafish for ratiometric imaging of cytosolic and mitochondrial Ca2+ response in teleost embryo
    Hideaki Mizuno
    Cell Function and Dynamics, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako City, Saitama 351 0198, Japan
    Cell Calcium 54:236-45. 2013
    ..This is in contrast with the transient rise in the cytosol Ca2+ that directly evokes the muscle contraction. These transgenic zebrafish lines are expected to serve as useful tools further Ca2+ imaging in vivo...
  30. ncbi request reprint Zebrafish gcmb is required for pharyngeal cartilage formation
    Ryuki Hanaoka
    Laboratory for Developmental Gene Regulation, The Institute of Physical and Chemical Research, RIKEN Brain Science Institute, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Mech Dev 121:1235-47. 2004
    ..These results suggest that gcmb is required for normal pharyngeal cartilage formation in zebrafish and that its expression is dependent on fgf3 activity...
  31. doi request reprint The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation
    Hidenori Aizawa
    RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan, Tokyo Medical and Dental University Medical Research Institute, Bunkyo ku, Tokyo 113 8510, Japan
    J Neurosci 33:8909-21. 2013
    ....
  32. doi request reprint Molecular characterization of the subnuclei in rat habenula
    Hidenori Aizawa
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama, Japan
    J Comp Neurol 520:4051-66. 2012
    ..These analyses clarify molecular differences between subnuclei in the mammalian habenula that support their respective functional implications...
  33. ncbi request reprint Efficient transfection strategy for the spatiotemporal control of gene expression in zebrafish
    Hideki Ando
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN The Institute of Physical and Chemical Research, Wako, Saitama, 351 0198, Japan
    Mar Biotechnol (NY) 8:295-303. 2006
    ..Co-lipofection of MO and GFP mRNA to the presumptive head region resulted in brain-specific knockdown of the gene in mid-stage embryos...
  34. ncbi request reprint Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish
    Sang Yeob Yeo
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako, Saitama 351 0198, Japan
    Mech Dev 121:315-24. 2004
    ....
  35. ncbi request reprint R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development
    Motoko Aoki
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Dev Growth Differ 50:85-95. 2008
    ..This study shows that Rspo2 is critical for maintenance of the AER and for growth and patterning in limb development...
  36. ncbi request reprint Systematic identification of factors in zebrafish regulating the early midbrain and cerebellar development by odered differential display and caged mRNA technology
    Hitoshi Okamoto
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198 Japan
    Front Biosci 9:93-9. 2004
    ..Our strategy and technologies can be applied to analyzing the downstream genes of any other transcription factors...
  37. pmc Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization
    Douglas S Campbell
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Cell Biol 203:657-72. 2013
    ....
  38. ncbi request reprint Canopy1, a novel regulator of FGF signaling around the midbrain-hindbrain boundary in zebrafish
    Yoshikazu Hirate
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198, Japan
    Curr Biol 16:421-7. 2006
    ..This study highlights a positive-feedback loop between the FGFR pathway and Cnpy1 that may ensure the strength of FGF signaling in the MHB, leading to correct development of the tectum and cerebellum...
  39. doi request reprint Molecular characterization of the subnuclei in rat habenula
    Hidenori Aizawa
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan Department of Molecular Neuroscience, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo ku, Tokyo 113 8510 Japan
    J Comp Neurol 520:Spc1. 2012
    ..These analyses clarify molecular differences between subnuclei in the mammalian habenula that support their respective functional implications. J. Comp. Neurol. 520:4051-4066, 2012. © 2012 Wiley Periodicals, Inc...
  40. ncbi request reprint Practical procedures for ectopic induction of gene expression in zebrafish embryos using Bhc-diazo-caged mRNA
    Hideki Ando
    Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako, Saitama 351 0198, Japan
    Methods Cell Sci 25:25-31. 2003
    ..In this paper we describe the technique and detailed procedures for spatially and temporally controlled induction of gene expression in zebrafish embryos...
  41. ncbi request reprint [Photo-mediated gene activation/inactivation by novel caging agent]
    Hideki Ando
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, Institute of Physical and Chemical Research, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Seikagaku 75:1251-4. 2003
  42. ncbi request reprint R-spondin3 is required for mouse placental development
    Motoko Aoki
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama, Japan
    Dev Biol 301:218-26. 2007
    ..These findings suggest a critical role for Rspo3 in the interaction between chorion and allantois in labyrinthine development...
  43. doi request reprint Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons
    Makoto Aoki
    Laboratory for Developmental Gene Regulation, Brain Science Institute, RIKEN, Japan
    Biochem Biophys Res Commun 445:357-62. 2014
    ..They are not reported the involvement of axonal extension or their functions in neural cells. Finally, knockdown of these genes suggested their direct actual involvement in the extension of peripheral axons in sensory neurons. ..
  44. ncbi request reprint N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites
    Ichiro Masai
    Masai Initiative Research Unit, The Institute of Physical and Chemical Research RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Development 130:2479-94. 2003
    ..Although in vitro studies have implicated Fgf receptors in modulating the axon outgrowth promoting properties of Ncad, most aspects of the Ncad mutant phenotype are not phenocopied by treatments that block Fgf receptor function...
  45. ncbi request reprint Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues
    Jörg Zeller
    RIKEN Brain Science Institute, Saitama, Japan
    Dev Biol 252:241-56. 2002
    ..In summary, we provide compelling evidence that myotomal cells produce multiple signals to initiate and control the migration of spinal nerve axons into the somites...
  46. ncbi request reprint Zebrafish research in Japan and the National BioResource Project
    Hitoshi Okamoto
    RIKEN Brain Science Institute, Wako, Saitama, Japan
    Exp Anim 59:9-12. 2010
    ..Due to these circumstances, a system to collect, preserve, and provide zebrafish strains was established as part of the National BioResource Project useful model vertebrates in Japan and to the world...
  47. doi request reprint Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53
    Masahiro Yamaguchi
    Developmental Neurobiology Unit, Initial Research Project, Okinawa Institute of Science and Technology Promotion Corporation, 12 2 Suzaki, Uruma shi, Okinawa 904 2234, Japan
    Development 135:1247-57. 2008
    ..These data suggest that the surveillance system of genome integrity strongly influences the cell fate decision between differentiation and apoptosis during retinal neurogenesis in zebrafish...
  48. ncbi request reprint Chemokine signaling guides axons within the retina in zebrafish
    Qin Li
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109 1048, USA
    J Neurosci 25:1711-7. 2005
    ..These data suggest that chemokine signaling is both necessary and sufficient for directing retinal growth cones within the retina...
  49. ncbi request reprint The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling
    Atsushi Kawakami
    Department of Biological Science, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Curr Biol 15:480-8. 2005
    ..We further show that Bmp activity can be attenuated by the coexpression of Scube2. Our data support the idea that Scube2 can modulate the long-range action of Bmp-dependent signaling in the neural tube and somites...
  50. ncbi request reprint Role of Bone morphogenetic protein 4 in zebrafish semicircular canal development
    Yasuhiro Omata
    Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Seiryou machi 4 1, Sendai 980 8575, Japan
    Dev Growth Differ 49:711-9. 2007
    ..Furthermore, the protrusions in gallery treated with Noggin were partially rescued. These data indicate that BMP4 plays an important role in the development of protrusions to form semicircular canals...
  51. ncbi request reprint Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish
    Yumi Emoto
    Department of Biological Information, Tokyo Institute of Technology, Yokohama 226 8501, Japan
    Dev Biol 278:415-27. 2005
    ..We propose a model in which Cyp26a1 attenuates RA signaling in the prospective rostral spinal cord to limit the expression of hox genes and to determine the hindbrain-spinal cord boundary...
  52. ncbi request reprint [Development of a new technology to manipulate gene activity by photo-illumination using a new DNA/RNA caging compound, Bhc-diazo]
    Hideki Ando
    Tanpakushitsu Kakusan Koso 47:125-32. 2002
  53. pmc The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons
    Stephanie Bingham
    Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211, USA
    Dev Biol 242:149-60. 2002
    ..We conclude that trilobite function is specifically required for two types of cell migration that occur at different stages of zebrafish development...
  54. ncbi request reprint Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways
    Masahiro Yamaguchi
    Masai Initiative Research Unit, RIKEN The Institute of Physical and Chemical Research
    Development 132:3027-43. 2005
    ..Taken together, these data suggest that Hdac1 functions as a dual switch that suppresses both cell-cycle progression and inhibition of neurogenesis in the zebrafish retina...
  55. ncbi request reprint Two divergent slit1 genes in zebrafish
    Lara D Hutson
    Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah 84132, USA
    Dev Dyn 228:358-69. 2003
    ..Their expression patterns, particularly that of slit1a, suggest that Slit proteins may have roles in tissue morphogenesis in addition to their established roles in axon guidance and cell migration...
  56. ncbi request reprint Structure of the zebrafish fasciclin I-related extracellular matrix protein (betaig-h3) and its characteristic expression during embryogenesis
    Yoshikazu Hirate
    Department of Regulation Biology, Faculty of Science, Saitama University, 338 8570 Saitama, Japan
    Gene Expr Patterns 3:331-6. 2003
    ..In addition, new expression starts in the mesenchyme cells in the head, pharyngeal arches, and pectoral fins. In the embryonic brain, expression is observed along the anterior and postoptic commissures, as well as along the optic nerve...