Hiroshi Ohno


Affiliation: RIKEN Brain Science Institute
Country: Japan


  1. Ong J, Taylor T, Yong C, Khoo B, Sasidharan S, Choi S, et al. Lactobacillus plantarum USM8613 Aids in Wound Healing and Suppresses Staphylococcus aureus Infection at Wound Sites. Probiotics Antimicrob Proteins. 2019;: pubmed publisher
    ..aureus. Taken altogether, our present study illustrates the potential of L. plantarum USM8613 in aiding wound healing, suppressing of S. aureus infection at wound sites and promoting host innate immunity. ..
  2. Ohno H. Intestinal M cells. J Biochem. 2016;159:151-60 pubmed publisher
    ..I will discuss recent advances in our understanding of the molecular mechanisms of M-cell differentiation and functions. ..
  3. Kanaya T, Sakakibara S, Jinnohara T, Hachisuka M, Tachibana N, Hidano S, et al. Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling. J Exp Med. 2018;215:501-519 pubmed publisher
    ..In addition, the expression of FAE-associated genes is almost silenced in TRAF6-deficient mice. This study thus demonstrates the crucial role of TRAF6-mediated NF-κB signaling in the development of M cells and FAE. ..
  4. Jinnohara T, Kanaya T, Hase K, Sakakibara S, Kato T, Tachibana N, et al. IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake. J Exp Med. 2017;214:1607-1618 pubmed publisher
    ..Our present study thus demonstrates that IL-22BP promotes bacterial uptake into PPs by influencing FAE gene expression and function. ..
  5. Shimokawa C, Kanaya T, Hachisuka M, Ishiwata K, Hisaeda H, Kurashima Y, et al. Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. Immunity. 2017;46:863-874.e4 pubmed publisher
  6. Lye H, Kato T, Low W, Taylor T, Prakash T, Lew L, et al. Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration of gut microbiota. J Biotechnol. 2017;262:75-83 pubmed publisher
    ..Overall, we demonstrated that FTDC 8312 exerted a cholesterol lowering effect that may be attributed to gut microbiota modulation. ..