Genomes and Genes


Hiroshi Masuya


Affiliation: RIKEN Brain Science Institute
Country: Japan


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    Masuya H, Nishida K, Furuichi T, Toki H, Nishimura G, Kawabata H, et al. A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice. Hum Mol Genet. 2007;16:2366-75 pubmed
    ..This study further highlights a critical role of GDF5 in joint formation and the development of OA, and this mouse should serve as a good model for OA. ..