Research Topics
Genomes and Genes | Raj K LadherSummaryAffiliation: RIKEN Brain Science Institute Country: Japan Publications
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Detail Information
Publications
From shared lineage to distinct functions: the development of the inner ear and epibranchial placodesRaj K Ladher
RIKEN Center for Developmental Biology, Chuoku, Kobe 650 0047, Japan
Development 137:1777-85. 2010..This review summarises recent studies into the induction, morphogenesis and innervation of these systems and discusses lineage restriction and cell specification in the context of their common origin...
FGF8 initiates inner ear induction in chick and mouseRaj K Ladher
Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe 650 0047, Japan
Genes Dev 19:603-13. 2005..Thus, Fgf8 plays a critical upstream role in an FGF signaling cascade required for otic induction in chick and mouse...
Induction of the chick columella and its integration with the inner earYihui Zou
RIKEN Center for Developmental Biology, Kobe, Japan
Dev Dyn 241:1104-10. 2012..The independent lineages of the two suggest that some mechanism must exist that ensures the connectivity between the inner ear and the columella; however, the basis of integration is not known...
Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potentialSabine Freter
Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
Development 135:3415-24. 2008..This interplay of signalling factors ensures the correct and ordered differentiation of both inner ear and epibranchial systems...
Pax2 modulates proliferation during specification of the otic and epibranchial placodesSabine Freter
Laboratory for Sensory Development, RIKEN Center for Developmental Biology, Kobe, Japan
Dev Dyn 241:1716-28. 2012..One role of Pax2 is to maintain proper cell cycle proliferation in the PPA. Developmental Dynamics 241:1716-1728, 2012. © 2012 Wiley Periodicals, Inc...
The amniote paratympanic organ develops from a previously undiscovered sensory placodePaul O'Neill
Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
Nat Commun 3:1041. 2012..We hypothesize that the paratympanic organ/spiracular organ represents an ancient head ectoderm module, developmentally and evolutionarily independent of both lateral line and epibranchial placodes...
FGF signaling regulates cytoskeletal remodeling during epithelial morphogenesisXiaorei Sai
Laboratory for Sensory Development, RIKEN Kobe Institute, Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 640 0047, Japan
Curr Biol 18:976-81. 2008..The iteration of this morphogenetic signaling system suggests that it is a more generally applicable mechanism in other epithelial tissues undergoing shape change...
Rostral paraxial mesoderm regulates refinement of the eye field through the bone morphogenetic protein (BMP) pathwayMichael E Teraoka
Laboratory for Sensory Development, RIKEN Kobe Institute Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 650 0047, Japan
Dev Biol 330:389-98. 2009..The rostral paraxial mesoderm expresses members of the bone morphogenetic protein (BMP) family of signalling molecules and manipulation of endogenous BMP signalling resulted in abnormalities of the early optic primordia...
Hair cell differentiation becomes tissue specific by E9.5 in mouse inner earTatsunori Sakamoto
Lab for Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe, Japan
Neuroreport 18:841-4. 2007..0 mice could not. This indicates that the mouse otocyst gains the ability to generate hair cells between E9.0 and E9.5 and that this ability depends on signals from the surrounding mesenchyme and/or the hindbrain...
Comparison of the expression patterns of several fibroblast growth factors during chick gastrulation and neurulationHakan Karabagli
Department of Neurosurgery, Haydarpasa Numune Educational Hospital, Istanbul, Turkey
Anat Embryol (Berl) 205:365-70. 2002..As well as providing a comparison of the expression patterns of those fibroblast growth factors already published, we provide new data on the expression patterns of some of these genes at early stages...
Survey of fibroblast growth factor expression during chick organogenesisHakan Karabagli
Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, USA
Anat Rec 268:1-6. 2002..We show the expression patterns of fgf-2, -3, -4, -8, -10, -12, -13, -14, and -18 in the head, trunk, limbs, heart, and tail of the embryo...
Development of the sensory organsPhilippa H Francis-West
Department of Craniofacial Development, King's College London, London Bridge, SE1 9RT
Sci Prog 85:151-73. 2002..This review highlights the current knowledge of placode development and the future challenges in unravelling the cascades of signalling interactions that control development of these unique structures...
