Raj K Ladher

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. pmc FGF8 initiates inner ear induction in chick and mouse
    Raj K Ladher
    Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe 650 0047, Japan
    Genes Dev 19:603-13. 2005
  2. doi request reprint From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes
    Raj K Ladher
    RIKEN Center for Developmental Biology, Chuoku, Kobe 650 0047, Japan
    Development 137:1777-85. 2010
  3. doi request reprint Pax2 modulates proliferation during specification of the otic and epibranchial placodes
    Sabine Freter
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, Japan
    Dev Dyn 241:1716-28. 2012
  4. pmc The amniote paratympanic organ develops from a previously undiscovered sensory placode
    Paul O'Neill
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Nat Commun 3:1041. 2012
  5. doi request reprint Induction of the chick columella and its integration with the inner ear
    Yihui Zou
    RIKEN Center for Developmental Biology, Kobe, Japan
    Dev Dyn 241:1104-10. 2012
  6. doi request reprint Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential
    Sabine Freter
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Development 135:3415-24. 2008
  7. pmc Retinoic acid regulates olfactory progenitor cell fate and differentiation
    Marie Paschaki
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, Kobe 650 0047, Japan
    Neural Dev 8:13. 2013
  8. doi request reprint Rostral paraxial mesoderm regulates refinement of the eye field through the bone morphogenetic protein (BMP) pathway
    Michael E Teraoka
    Laboratory for Sensory Development, RIKEN Kobe Institute Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 650 0047, Japan
    Dev Biol 330:389-98. 2009
  9. doi request reprint FGF signaling regulates cytoskeletal remodeling during epithelial morphogenesis
    Xiaorei Sai
    Laboratory for Sensory Development, RIKEN Kobe Institute, Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 640 0047, Japan
    Curr Biol 18:976-81. 2008
  10. ncbi request reprint Hair cell differentiation becomes tissue specific by E9.5 in mouse inner ear
    Tatsunori Sakamoto
    Lab for Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe, Japan
    Neuroreport 18:841-4. 2007

Collaborators

Detail Information

Publications13

  1. pmc FGF8 initiates inner ear induction in chick and mouse
    Raj K Ladher
    Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe 650 0047, Japan
    Genes Dev 19:603-13. 2005
    ..Thus, Fgf8 plays a critical upstream role in an FGF signaling cascade required for otic induction in chick and mouse...
  2. doi request reprint From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes
    Raj K Ladher
    RIKEN Center for Developmental Biology, Chuoku, Kobe 650 0047, Japan
    Development 137:1777-85. 2010
    ..This review summarises recent studies into the induction, morphogenesis and innervation of these systems and discusses lineage restriction and cell specification in the context of their common origin...
  3. doi request reprint Pax2 modulates proliferation during specification of the otic and epibranchial placodes
    Sabine Freter
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, Japan
    Dev Dyn 241:1716-28. 2012
    ..Loss-of- and gain-of function studies have defined a role for Pax2 in placodal morphogenesis and later inner ear development, but have not addressed the role Pax2 plays during the formation and maintenance of the PPA...
  4. pmc The amniote paratympanic organ develops from a previously undiscovered sensory placode
    Paul O'Neill
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Nat Commun 3:1041. 2012
    ..We hypothesize that the paratympanic organ/spiracular organ represents an ancient head ectoderm module, developmentally and evolutionarily independent of both lateral line and epibranchial placodes...
  5. doi request reprint Induction of the chick columella and its integration with the inner ear
    Yihui Zou
    RIKEN Center for Developmental Biology, Kobe, Japan
    Dev Dyn 241:1104-10. 2012
    ..The independent lineages of the two suggest that some mechanism must exist that ensures the connectivity between the inner ear and the columella; however, the basis of integration is not known...
  6. doi request reprint Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential
    Sabine Freter
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Development 135:3415-24. 2008
    ..This interplay of signalling factors ensures the correct and ordered differentiation of both inner ear and epibranchial systems...
  7. pmc Retinoic acid regulates olfactory progenitor cell fate and differentiation
    Marie Paschaki
    Laboratory for Sensory Development, RIKEN Center for Developmental Biology, Kobe 650 0047, Japan
    Neural Dev 8:13. 2013
    ....
  8. doi request reprint Rostral paraxial mesoderm regulates refinement of the eye field through the bone morphogenetic protein (BMP) pathway
    Michael E Teraoka
    Laboratory for Sensory Development, RIKEN Kobe Institute Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 650 0047, Japan
    Dev Biol 330:389-98. 2009
    ..The rostral paraxial mesoderm expresses members of the bone morphogenetic protein (BMP) family of signalling molecules and manipulation of endogenous BMP signalling resulted in abnormalities of the early optic primordia...
  9. doi request reprint FGF signaling regulates cytoskeletal remodeling during epithelial morphogenesis
    Xiaorei Sai
    Laboratory for Sensory Development, RIKEN Kobe Institute, Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, 640 0047, Japan
    Curr Biol 18:976-81. 2008
    ..The iteration of this morphogenetic signaling system suggests that it is a more generally applicable mechanism in other epithelial tissues undergoing shape change...
  10. ncbi request reprint Hair cell differentiation becomes tissue specific by E9.5 in mouse inner ear
    Tatsunori Sakamoto
    Lab for Sensory Development, RIKEN Center for Developmental Biology, Chuo Ku, Kobe, Japan
    Neuroreport 18:841-4. 2007
    ..0 mice could not. This indicates that the mouse otocyst gains the ability to generate hair cells between E9.0 and E9.5 and that this ability depends on signals from the surrounding mesenchyme and/or the hindbrain...
  11. ncbi request reprint Comparison of the expression patterns of several fibroblast growth factors during chick gastrulation and neurulation
    Hakan Karabagli
    Department of Neurosurgery, Haydarpasa Numune Educational Hospital, Istanbul, Turkey
    Anat Embryol (Berl) 205:365-70. 2002
    ..As well as providing a comparison of the expression patterns of those fibroblast growth factors already published, we provide new data on the expression patterns of some of these genes at early stages...
  12. ncbi request reprint Survey of fibroblast growth factor expression during chick organogenesis
    Hakan Karabagli
    Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, USA
    Anat Rec 268:1-6. 2002
    ..We show the expression patterns of fgf-2, -3, -4, -8, -10, -12, -13, -14, and -18 in the head, trunk, limbs, heart, and tail of the embryo...
  13. ncbi request reprint Development of the sensory organs
    Philippa H Francis-West
    Department of Craniofacial Development, King s College London, London Bridge, SE1 9RT
    Sci Prog 85:151-73. 2002
    ..This review highlights the current knowledge of placode development and the future challenges in unravelling the cascades of signalling interactions that control development of these unique structures...