Affiliation: RIKEN Brain Science Institute
- Micro-optical fiber probe for use in an intravascular Raman endoscopeYuichi Komachi
Probing Technology Laboratory, RIKEN The Institute of Physical and Chemical Research, Hirosawa, Wako Shi, Saitama 351 0198, Japan
Appl Opt 44:4722-32. 2005..Measurement of the Raman spectra of an atherosclerotic lesion of a rabbit artery in vitro demonstrates the excellent performance of the micro-Raman probe...
- Raman probe using a single hollow waveguideYuichi Komachi
Probing Technology Laboratory, RIKEN, The Institute of Physical and Chemical Research, Hirosawa, Wako Shi 351 0198, Japan
Opt Lett 30:2942-4. 2005..In addition, the measured Raman spectra showed better signal-to-noise ratios than a conventional Raman fiber probe. The HW's suitability as a Raman fiber probe was also demonstrated...
- Intravascular Raman spectroscopic catheter for molecular diagnosis of atherosclerotic coronary diseaseYuichi Komachi
Tashiro Probing Technology Laboratory, RIKEN The Institute of Physical and Chemical Research, Hirosawa, Wako Shi, Saitama, Japan
Appl Opt 45:7938-43. 2006..Results obtained demonstrate the possibility of using the spectroscopic catheter for molecular diagnosis of coronary lesions...
- In vivo Raman study of the living rat esophagus and stomach using a micro-Raman probe under an endoscopeYusuke Hattori
Optical Biopsy Development Research Unit, The Institute of Physical and Chemical Research RIKEN, 2 1 Hirosawa, Wako Shi, 351 0198, Japan
Appl Spectrosc 61:579-84. 2007..After the experiments, rats recover without any aftereffects. It is verified that the Raman measurement using the present system is safe and noninvasive for rats...
- Fluorescence-suppressed Raman technique for quantitative analysis of protein solution using a micro-Raman probe, the shifted excitation method, and partial least squares regression analysisYusuke Oshima
Tashiro Probing Technology Laboratory, RIKEN (The Institute of Physical and Chemical Research, Hirosawa, Wako-shi, Saitama 351-0198, Japan
Appl Spectrosc 60:964-70. 2006..The present study demonstrates that the technique is effective for extracting quantitative information concealed behind a fluorescent background that is more than 200 times stronger than the Raman signal...
- Detection of ER stress in vivo by Raman spectroscopyAkira Hosoda
Iwawaki Initiative Research Unit, Advanced Science Institute, RIKEN, Wako, Saitama, Japan
Biochem Biophys Res Commun 405:37-41. 2011..This suggests that Raman spectroscopy could be a useful tool to detect ER stress in vivo without transgenic technology...